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Further evidence of joint time-place control of rats' behavior: results from an 'open hopper' test.

Rats were trained on an interval time-place task. Food was intermittently available on each of four levers for 4 min in a 16-min session. After baseline training the rats received 'open hopper' sessions in which food was available on all levers for all of the 16-min sessions. Despite the absence of any contingencies for doing so, the rats continued to press the levers in the 'correct' sequence, for roughly the 'correct' amount of time. This confirms that the rat behavior was controlled, in part, by a representation of an elapsed interval of time. The rats responding was more variable in 'open hopper' sessions and error increased (in an exponential fashion) as the session proceeded. This finding suggests that the rats may have used shifts in the location of food availability to minimize the accumulation of error throughout baseline sessions.

Journal Article↗

Applying the theory of planned behavior to women's behavioral attitudes on and consumption of soy products.

OBJECTIVE: To identify variables that significantly predict the intention and behavior concerning soy consumption applying the Theory of Planned Behavior and to determine the role of race on women's perspectives and consumption behaviors concerning soy. DESIGN: Cross-sectional survey, with self-administered questionnaires. SETTING: City park service programs, community organizations, black cultural classes, and university offices. PARTICIPANTS: A convenience sample of 205 black (n = 103) and white (n = 102) women. VARIABLES MEASURED: Women's behavioral attitudes, subjective norms, perceived behavioral control, intention, and behavior related to soy consumption. ANALYSIS: Correlation and stepwise regression analysis. RESULTS: All variables in the Theory of Planned Behavior showed significant correlations with behavioral intention, with behavioral attitudes exhibiting the strongest correlation (r = .57, P < .01). Stepwise multiple regression analyses revealed that behavioral attitude toward taste and subjective norms accounted for 47.7% of the variance in behavioral intention. Behavioral attitude toward taste explained 48.6% of the variability in behavior. There was no difference between races for consumption or Theory of Planned Behavior variables. CONCLUSIONS AND IMPLICATIONS: A negative attitude toward the taste of soy was the major predictor for low soy consumption. However, future studies should be undertaken to verify this relationship once more women become aware of and have tasted soy.

Adolescent↗

From psychological need satisfaction to intentional behavior: testing a motivational sequence in two behavioral contexts.

The present study tested a motivational sequence in which global-level psychological need satisfaction from self-determination theory influenced intentions and behavior directly and indirectly through contextual-level motivation and situational-level decision-making constructs from the theory of planned behavior. Two samples of university students (N = 511) completed measures of global-level psychological need satisfaction, contextual-level autonomous motivation, and situational-level attitudes, subjective norms, perceived behavioral control, intentions, and behavior in two behavioral contexts: exercise and dieting. A structural equation model supported the proposed sequence in both samples. The indirect effect was present for exercise behavior, whereas both direct and indirect effects were found for dieting behavior. Findings independently supported the component theories and provided a comprehensive integrated explanation of volitional behavior.

Adult↗

Relations between family structure and students' health-related attitudes and behaviors.

This study examined the relations between family structure and students' health-related behaviors. Participants were 6,130 Greek students, ages 11 to 16 years. They responded to questionnaires based on the Planned Behavior model assessing attitudes, perceived behavioral control, intentions and behavior regarding healthy and unhealthy habits. Students who reported growing up with one or no parent reported more unhealthy lifestyle attitudes and behaviors (smoking, drug use, violence, exercise, nutrition) than students growing up with both parents. The findings suggest that family structure is related to students' healthy or unhealthy lifestyle, indicating that in health education programs all members of the close environment within which the children live should be involved, especially for children who do not live with both parents.

Adolescent↗

Hopelessness in Chinese adolescents in Hong Kong: demographic and family correlates.

Chinese secondary school students (N = 3,017) responded to measures of adolescent hopelessness, perceived parental behavioral control (indexed by parental knowledge, expectation, monitoring, discipline, and demandingness, as well as Chinese parental control attributes), parental psychological control, and parent-child relational qualities (satisfaction with parental control, child's readiness to communicate with the parents and perceived mutual trust). Results showed that roughly one-fifth of Chinese adolescents displayed signs of hopelessness and adolescent hopelessness was related to adolescent age and gender as well as parental education and marital status. Although parental behavioral control was negatively related to adolescent hopelessness, parental psychological control was positively associated with adolescent hopelessness. Participants perceived parent-child relational qualities to be better showed lower levels of hopelessness.

Adolescent↗

[Eating disorders in early adolescence--study from the section on young adolescent nutrition in Jerusalem].

Young adolescents were assessed with regard to cognitive, socio-cultural and behavioral components of eating disturbances. An anonymous questionnaire was administered to 5th-8th grade pupils, 280 girls and 251 boys, to assess eating habits, body image, self-confidence, environmental-cultural influences, risk behaviors and socio-economic state. Girls scored consistently higher on all weight-control behaviors. Discontent with own body, and attitudes and behaviors associated with eating disorders, were reported by under-studied populations such as boys and younger girls. Both frequency and severity of weight-control behaviors were associated with "social age." Highly significant differences between scores of 6th and 7th graders indicate that they may be at a time of increased susceptibility. Measuring the influence of the mass media gave inconsistent results.

Adolescent↗

Genetic correlation between performance on an appetitive-signaled nosepoke task and voluntary ethanol consumption.

The present study used a signaled appetitive nosepoke task as a measure of behavioral control or impulsivity related to reward system function in mice and determined how impulsivity correlated with voluntary ethanol consumption. Thirteen inbred strains were trained to nosepoke for food rewards and eventually trained to nosepoke for reward when an auditory signal was presented. Efficiency in the signaled nosepoke task indicated the ability of the mice to withhold the nosepoke response until the signal to respond for a reward was given and was considered indicative of behavioral control or impulsivity. After completion of the nosepoke task, the mice were tested for ethanol consumption in a three-bottle choice test at 3 and 10% (v/v) ethanol concentrations. Behavioral measures from the nosepoke task and ethanol consumption measures were correlated to determine a genetic relationship. High efficiency, the ability to withhold nosepoking until signaled, was negatively correlated with ethanol consumption. Thus, the strains who were better able to control their behavioral responding (i.e., less impulsive) consumed less ethanol, and strains who were more impulsive consumed more ethanol. This genetic relationship may be a mouse behavioral model for some of the neuropsychological traits demonstrated in human subjects who are family history-positive for alcoholism.

Alcohol Drinking↗

Understanding the determinants of exercise intentions in multiple myeloma cancer survivors: an application of the theory of planned behavior.

The purpose of this study was to examine the demographic, medical, and social cognitive determinants of exercise intentions in a population-based sample of multiple myeloma cancer survivors. Using a cross-sectional survey, 70 multiple myeloma cancer survivors completed a questionnaire that assessed their medical and demographic characteristics, past exercise behavior, and social cognitive exercise beliefs using the theory of planned behavior. Seventy participants provided valuable data. Descriptive statistics indicated that participants had quite positive instrumental attitude, intentions, and subjective norms and moderate levels of perceived behavioral control and affective attitudes for exercise. Forced entry multiple regression showed that the theory of planned behavior explained 43% of the variance in exercise intentions. Instrumental attitude and perceived behavioral control were both independent predictors of exercise intentions. No demographic or medical variable moderated the association between the theory of planned behavior constructs and exercise intentions. The results of the present investigation support the growing body of evidence confirming the utility of the theory of planned behavior to understand the salient determinants of exercise in cancer survivors. Knowledge gained from this study provides important information to oncology practitioners who are responsible for delivering supportive care interventions, including exercise, to patients diagnosed with multiple myeloma.

Adult↗

Modulation of involuntary and voluntary behavior following emotional stimuli in healthy subjects.

INTRODUCTION: Alterations of behavior control are core symptoms of various psychiatric disorders. Patients present with changes in complex behavior patterns and basic motor functions. Little is known about emotional modulation of voluntary behavior. Therefore, a paradigm was developed to study simultaneously influence of emotions on voluntary and involuntary movements. METHOD: Healthy volunteers (n=30) documented aspects of their mood and personality including depression, anxiety, and impulsivity. Individuals were instructed to view color slides of different emotional content and switch off the slide after by pressing a button, which was placed in a standardized distance from the resting point. The startle reflex was elicited while looking at the slides and quantified by EMG. Kinematic measures of hand movements by infrared detection were used to analyze the patterns of voluntary movements. RESULTS: This study confirmed previous findings about the modulation of the startle reflex by emotional stimuli which may reflect activity of the amygdala and subcortical stimulus processing. Voluntary movements, which may result from cortical processing of stimuli, were not influenced by the emotional context. In individuals with higher impulsivity scores, the startle reflex amplitudes were lower and relative time to peak velocity of the movement smaller. CONCLUSION: Voluntary movements were not modulated by emotional stimuli, but time to peak velocity was shorter in individuals with greater impulsivity. The ability to generate adequate behavior as a key function of the brain is relevant for social functioning and activities of daily living. The studied paradigm could be useful to assess impulsivity and behavior control in psychiatric disorders.

Adult↗

Analysis of discriminative control by social behavioral stimuli.

Visual discriminative control of the behavior of one rat by the behavior of another was studied in a two-compartment chamber. Each rat's compartment had a food cup and two response keys arranged vertically next to the clear partition that separated the two rats. Illumination of the leader's key lights signaled a "search" period when a response by the leader on the unsignaled and randomly selected correct key for that trial illuminated the follower's keys. Then, a response by the follower on the corresponding key was reinforced, or a response on the incorrect key terminated the trial without reinforcement. Accuracy of following the leader increased to 85% within 15 sessions. Blocking the view of the leader reduced accuracy but not to chance levels. Apparent control by visual behavioral stimuli was also affected by auditory stimuli and a correction procedure. When white noise eliminated auditory cues, social learning was not acquired as fast nor as completely. A reductionistic position holds that behavioral stimuli are the same as nonsocial stimuli; however, that does not mean that they do not require any separate treatment. Behavioral stimuli are usually more variable than nonsocial stimuli, and further study is required to disentangle behavioral and nonsocial contributions to the stimulus control of social interactions.

Journal Article↗

Cocaine improves inhibitory control in a human model of response conflict.

The present study was designed to test the acute effects of cocaine on behavioral control in the presence and absence of motivational conflict. Adults (N = 14) with a history of stimulant use received oral cocaine hydrogen chloride (0, 100, 200, and 300 mg) and performed a cue-dependent go/no-go task to measure inhibitory and activational mechanisms of behavioral control either with or without motivated conflict between the inhibition and the activation of responses. Cocaine improved response inhibition in both conflict conditions, as evident by a decrease in inhibitory failures following active doses. The current study provides a useful model to investigate the effects of other drugs reported to have performance-enhancing effects.

Administration, Oral↗

Control, compliance, and satisfaction in the family practice encounter.

BACKGROUND AND OBJECTIVES: With the current emphasis on patient-centered interviewing, issues of control behavior have become an important facet for understanding effective physician-patient communication. In this study, we describe how verbal control behaviors are manifested during the clinical encounter and how these control patterns relate to patient satisfaction and compliance. METHODS: Videotaped encounters (n = 50) in a family practice residency clinic were transcribed and analyzed using the Relational Communication Control Coding Scheme. In addition, we surveyed patients to assess levels of compliance and satisfaction. RESULTS: Overall, patients showed assertive control patterns, and physicians manifested patterns of willingness to let patients take control of the conversation. The resulting outcomes showed that when physicians exhibited less control dominance, there was an increase in patient compliance and satisfaction. CONCLUSIONS: The control patterns discovered are consistent with patient-centered viewpoints that encourage the patient's expression of ideas, concerns, and expectations. Increased levels of patient satisfaction and compliance were found when patients more assertively participated in the clinical conversation.

Adolescent↗

The effects of extinction, noncontingent reinforcement and differential reinforcement of other behavior as control procedures.

Several techniques have been used in applied research as controls for the introduction of a reinforcement contingency, including extinction, noncontingent reinforcement (NCR), and differential reinforcement of other behavior (DRO). Little research, however, has examined the relative strengths and limitations of these "reversal" controls. We compared the effects of extinction with those of NCR and DRO in both multi-element and reversal designs, with respect to (a) rate and amount of response decrement, (b) rate of response recovery following reintroduction of reinforcement, and (c) any positive or negative side effects associated with transitions. Results indicated that extinction generally produced the most consistent and rapid reversal effects, with few observed negative side effects.

Adult↗

CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans.

Mutations in the clk-1 gene of the nematode Caenorhabditis elegans result in an average slowing of a variety of developmental and physiological processes, including the cell cycle, embryogenesis, post-embryonic growth, rhythmic behaviors and aging. In yeast, a CLK-1 homologue is absolutely required for ubiquinone biosynthesis and thus respiration. Here we show that CLK-1 is fully active when fused to green fluorescent protein and is found in the mitochondria of all somatic cells. The activity of mutant mitochondria, however, is only very slightly impaired, as measured in vivo by a dye-uptake assay, and in vitro by the activity of succinate cytochrome c reductase. Overexpression of CLK-1 activity in wild-type worms can increase mitochondrial activity, accelerate behavioral rates during aging and shorten life span, indicating that clk-1 regulates and controls these processes. These observations also provide strong genetic evidence that mitochondria are causally involved in aging. Furthermore, the reduced respiration of the long-lived clk-1 mutants suggests that longevity is promoted by the age-dependent decrease in mitochondrial function that is observed in most species.

Aging↗

Regulating managed care: interest group competition for control and behavioral health care.

In this essay I identify how historic patterns of competition among health care interest groups have simultaneously retained their past contours and also changed significantly as a result of the jolt created by the rise of managed care. I explain why it is that I and other executives of for-profit managed behavioral health care organizations, traditionally advocates of market-based approaches to accountability, have begun to support some versions of regulation by the national government in order to restore consumer confidence in the credibility of managed health plans. Key concepts that are addressed include notions of public accountability, control of the purse strings, consumer protections, and provider privileges.

Behavioral Medicine↗

Proteomic identification of brain proteins in the canine model of human aging following a long-term treatment with antioxidants and a program of behavioral enrichment: relevance to Alzheimer's disease.

Aging and age-related disorders such as Alzheimer's disease (AD) are usually accompanied by oxidative stress as one of the main mechanisms contributing to neurodegeneration and cognitive decline. Aging canines develop cognitive dysfunction and neuropathology similar to those seen in humans, and the use of antioxidants results in reductions in oxidative damage and in improvement in cognitive function in this canine model of human aging. In the present study, the effect of a long-term treatment with an antioxidant-fortified diet and a program of behavioral enrichment on oxidative damage was studied in aged canines. To identify the neurobiological mechanisms underlying these treatment effects, the parietal cortex from 23 beagle dogs (8.1-12.4 years) were treated for 2.8 years in one of four treatment groups: i.e., control food-control behavioral enrichment (CC); control food-behavioral enrichment (CE); antioxidant food-control behavioral enrichment (CA); enriched environment-antioxidant-fortified food (EA). We analyzed the levels of the oxidative stress biomarkers, i.e., protein carbonyls, 3-nitrotyrosine (3-NT), and the lipid peroxidation product, 4-hydroxynonenal (HNE), and observed a decrease in their levels on all treatments when compared to control, with the most significant effects found in the combined treatment, EA. Since EA treatment was most effective, we also carried out a comparative proteomics study to identify specific brain proteins that were differentially expressed and used a parallel redox proteomics approach to identify specific brain proteins that were less oxidized following EA. The specific protein carbonyl levels of glutamate dehydrogenase [NAD (P)], glyceraldehyde-3-phosphate dehydrogenase (GAPDH), alpha-enolase, neurofilament triplet L protein, glutathione-S-transferase (GST) and fascin actin bundling protein were significantly reduced in brain of EA-treated dogs compared to control. We also observed significant increases in expression of Cu/Zn superoxide dismutase, fructose-bisphosphate aldolase C, creatine kinase, glutamate dehydrogenase and glyceraldehyde-3-phosphate dehydrogenase. The increased expression of these proteins and in particular Cu/Zn SOD correlated with improved cognitive function. In addition, there was a significant increase in the enzymatic activities of glutathione-S-transferase (GST) and total superoxide dismutase (SOD), and significant increase in the protein levels of heme oxygenase (HO-1) in EA treated dogs compared to control. These findings suggest that the combined treatment reduces the levels of oxidative damage and improves the antioxidant reserve systems in the aging canine brain, and may contribute to improvements in learning and memory. These observations provide insights into a possible neurobiological mechanism underlying the effects of the combined treatment. These results support the combination treatments as a possible therapeutic approach that could be translated to the aging human population who are at risk for age-related neurodegenerative disorders, including Alzheimer's disease.

Aldehydes↗