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At least 685 records · Page 38Linked to original sources
PubMed2000

Costs and returns of camels, cattle and small ruminants in pastoral herds in eastern Ethiopia.

Two questionnaire surveys (2 x 44) were conducted among pastoral households, using three grazing management systems. The average number of Tropical Livestock Units (250 kg) was 4.0 per member of the household. Milk production was the most important source of revenue (66% of the total) followed by sale of livestock (17%) and transport (16%). High mortality rates were recorded for all livestock. About 27% of the milk was sold fresh or as butter. Sedentary and transhumant grazing management systems showed similar levels of income, but nomads had a 2.6-fold higher overall net income. The average total gross income from the entire herd amounted to US$ 6382 per household per year. The calculated costs were 29% of the gross returns. The contribution to the total gross revenues of camels, cattle and small ruminants was 58%, 25% and 17%, respectively.

Animal Husbandry↗
PubMed1998

The gross anatomy of the cranial cervical ganglion and its branches in the Bactrian camel (Camelus bactrianus).

Ten specimens of the head and neck of the Bactrian camel (Camelus bactrianus) were dissected to study the situation, arrangement and branches of the cranial cervical ganglion (ganglion cervicale craniale). The ganglion was a greyish fusiform structure, averaging 15-20 mm in length, 4-6 mm in width and 3 mm in thickness, located on the rostro-lateral surface of the longus capitis and covered by the mandibular gland. The branches of the cranial cervical ganglion included the internal carotid nerve, external carotid nerve, jugular nerve and the branches connecting with the glossopharyngeal, vagus, hypoglossal and first cervical nerves.

Animals↗
PubMed1998

The arterial supply of the metacarpophalangeal joint in the Bactrian camel (Camelus bactrianus).

The arterial supply of the six metacarpophalangeal joints was studied in Bactrian camels. The arterial branches supplying the metacarpophalangeal joints were derived from the metacarpal distal perforating, medial and lateral branches of the palmar metacarpal artery III, medial and lateral branches of the palmar common digital artery III and the abaxial palmar proper digital arteries III and IV. These arterial branches were the proximal dorsoaxial distal metacarpal, distal dorsoaxial distal metacarpal, abaxial distal metacarpal, palmar distal metacarpal, interosseous distal metacarpal, dorsoaxial proximal proximal phalangeal, palmoxial proximal proximal phalangeal, palmoabaxial proximal proximal phalangeal and dorsoabaxial proximal proximal phalangeal branches. They linked with each other around the metacarpophalangeal joint.

Animals↗
PubMed2000

The arterial supply of the cubital joint in the Bactrian camel (Camelus bactrianus).

The arterial supply of the six cubital joints from bactrian camels was studied. There were 15 arterial branches supplying the joint. The branches that arose from the transverse cubital artery were the medial anterior, superior anterior, lateral anterior, middle anterior, inferior anterior, superior lateral, middle lateral, inferior lateral, superior posterior and superior lateral posterior cubital branches. The branches originating from the collateral ulnar artery were the medial, middle posterior, inferior posterior, medial posterior and inferior lateral posterior cubital branches. These arteries united with each other around the cubital joint.

Animals↗
PubMed2001

Preliminary observations on the concentrations of serum luteinizing hormone and follicle-stimulating hormone during gestation in bactrian camels (Camelus bactrianus).

The concentrations of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in the serum of the Bactrian camel (Camelus bactrianus) throughout pregnancy were analysed by radioimmunoassay. The samples were withdrawn at intervals of half a month. The serum LH concentrations varied significantly between 2.2+/-0.9 and 20.3+/-18.8 ng/ml during the pregnancy, with the highest value on the day of artificial insemination, which indicated that a preovulatory LH peak appeared. Thereafter, the LH concentration tended to fall, reaching a fairly constant low level by the eighth month of pregnancy. The serum FSH concentrations varied between 7.0+/-0.2 and 28.9+/-0.4 ng/ml during gestation, with the peak value being reached at 4.5 months, followed by a marked drop to 7.0+/-0.2 ng/ml at 7.5 months.

Animals↗
PubMed2000

The arterial supply of the carpal joint in the Bactrian camel (Camelus bactrianus).

The arterial supply of the six carpal joints was studied in Bactrian camels. The arterial branches supplying the carpal joints were the proximal medial dorsal, middle medial dorsal, distal medial dorsal, proximal lateral dorsal, distal lateral dorsal, proximal medial palmar, distal medial palmar, lateral palmar, proximal palmar and dorsal palmar carpi and the dorsal interosseous antebrachium branches. Some small unnamed branches supplied the diverticulum and the antebrachiocarpal joint capsule. All these arteries arose from the lateral and medial branches of the radial artery.

Animals↗
PubMed2000

Serum lipids and lipoproteins in clinically healthy male Camels (Camelus dromedarius).

Blood samples were collected from the jugular vein of 87 Iranian male dromedary camels of different age groups (<3, 3-5, 5-6 and 6-8 years). Variations in the serum concentrations of cholesterol, triglyceride, total lipid, very low-density lipoprotein (VLDL-cholesterol), low-density lipoprotein (LDL-cholesterol) and high-density lipoprotein (HDL-cholesterol) were investigated. The concentrations of cholesterol, triglyceride, total lipid, HDL-cholesterol, LDL-cholesterol and VLDL-cholesterol in the different age groups were significantly different (p < 0.05). With an increase in the age of the animals, there were highly significant increases in the cholesterol, triglyceride, HDL-cholesterol and VLDL-cholesterol concentrations, whereas the concentration of LDL-cholesterol decreased (p < 0.001).

Age Factors↗
PubMed1998

On the inhibition of camel retina acetylcholinesterase activity by cycloheximide in vitro.

The kinetic parameters of inhibition of camel retinal acetylcholinesterase (AChE) activity by cycloheximide (CH) were investigated. For the control system, the Michaelis-Menten constant (K(m)) for the hydrolysis of acetylthiocholine iodide was found to be 0.076 mmol/L and the Vmax was 0.547 mumol/min per mg protein. In contrast, these parameters were decreased in the CH-treated systems. Dixon and Lineweaver-Burk plots, and their secondary replots, indicated that the inhibition was of the linear mixed type, which seems to be a combination of partial competitive and pure noncompetitive inhibition. The values of K'i(slope) and KI(intercept) were estimated to be 3.50 and 5.68 mmol/L, respectively. Ki was greater than K'i, indicating that CH has a greater binding affinity for the peripheral site than the active site.

Acetylcholine↗
PubMed2001

Purification and characterization of aspartate aminotransferase from developing embryos of the camel tick Hyalomma dromedarii.

Aspartate transaminase (AST) activity in the camel tick Hyalomma dromedarii was followed throughout embryogenesis. During purification of AST to homogeneity, ion exchange chromatography lead to four separate forms (termed I, II, III and IV). AST II with the highest specific activity was pure after chromatography on Sephacryl S-300. The molecular mass of AST II was 52 KDa for the native enzyme, composed of one subunit of 50 KDa. AST II had a Km value of 0.67mM for a-ketoglutarate and 15.1 mM for aspartate. AST II had a pH optimum of 7.5 with heat stability up to 50 degrees C for 15 min. The enzyme was activated by MnCl2, and inhibited by CaCl2, MgCl2. NiCl2, and ZnCl2.

Animals↗
PubMed2001

Isolation and properties of two forms of thrombin inhibitor from the nymphs of the camel tick Hyalomma dromedarii (Acari: Ixodidae).

Two forms of the nymphal thrombin inhibitors (NTI) 3.2 kDa and 14.9 kDa were purified by chromatography on CM-cellulose. Sephacryl S-300 and Sephadex G-50 columns and designated NTI- 1 and NTI-2 respectively. The NTI-2 turned out to be homogenous monomeric protein in both native-PAGE and denatured SDS-PAGE with M(r) value of 14.9 kDa approximately and its pI value ranged from 7.2 to 7.5. The NTI-1 and NTI-2 displayed anticoagulant activity since they prolonged both the activated partial thromboplastin time (APTT) and the prothrombin time (PT) of the camel plasma in a concentration-dependent manner. The potency of NTI-I toward thrombin was 5-fold higher than that toward FXa, while NTI-2 was 3-fold active toward FXa than thrombin. However, both of them did not inhibit any of the other examined proteases. The types of inhibition of thrombin by NTI-1 and NTI-2 were non-competitive and competitive with inhibition constants (Ki) values of 11.7 microM and 211 nM respectively. One binding site was deduced on thrombin for each inhibitor.

Animals↗
PubMed2002

The arterial supply to the eye of the bactrian camel (Camelus bactrianus).

The arterial supply to the eye of the bactrian camel (Camelus bactrianus) was studied by gross dissection. The supply came from the external ophthalmic, external ethmoidal and malar and maxillary tubercular arteries, ophthalmic rete mirabile, and the rostral epidural rete mirabile. The external ophthalmic artery gave rise to branches to supply the dorsal oblique muscle, lacrimal gland, superior and inferior eyelids, and the lateral angle of the eye, and to take part in the formation of the rostral epidural rete and the ophthalmic rete mirabile. The external ethmoidal artery detached off some branches to supply the ventral and medial dorsal rectus oblique muscles, the conjunctiva of the superior eyelid and the fat body of the orbit. The branches of the malar artery supplied the inferior, superior and third eyelids, ventral oblique muscle, and the medial angle of the eye. The ophthalmic rete mirabile gave off many branches to supply the rectus muscles of the eye, dorsal oblique and retractor oculi muscles, levator muscle of the superior eyelid, and the choroid.

Animals↗
PubMed2002

Silica urolithiasis in the dromedary camel in a subtropical climate.

In 1998, two cases of silica urolithiasis occurred in castrated male dromedaries on an intensive camel farm in the Canary Islands. The immediate attributable cause was the ingestion of large amounts of silica in the feed, estimated as 84.44 g/day. An associated cause was the low level of salt in the diet. Daily ingestion of salt from feed and water was estimated to be 21.8 g (8.6 g of sodium). Seventy-six castrated males from the same farm were divided into four groups: group A received 30 g of salt daily; group B received 40 g; group C received 60 g; and group D received no added salt in the diet (control). The animals were maintained on these dietary regimes for 2 years. No animals from groups A, B or C suffered overt urinary retention. One animal from group D had an obstructive urinary retention 10 months after the study commenced. Thus, 52 g of salt daily appears to be sufficient to prevent urinary retention in dromedaries raised in a subtropical climate.

Animal Feed↗
PubMed2004

Pharmacokinetics and pharmacodynamics of dexamethasone after intravenous administration in camels: effect of dose.

The pharmacokinetics and pharmacodynamics of dexamethasone were evaluated in healthy camels after single intravenous bolus doses of 0.05, 0.1 and 0.2 mg/kg body weight. Dexamethasone showed dose-independent pharmacokinetics. The pharmacokinetic parameters of the two-compartment pharmacokinetic model for the lowest intravenous dose (mean+/-SD) were as follows: terminal elimination half-life 8.17 +/- 1.79 h; total body clearance 100.7 +/- 52.1 (ml/h)/kg; volume of distribution at steady state 0.95 +/- 0.23 L/kg; and volume of the central compartment 0.22 +/- 0.07 L/kg. The extent of plasma protein binding was linear over the concentration range 5-100 ng/ml and averaged 75% +/- 2%. Pharmacodynamic effects were evaluated by measuring endogenous plasma cortisol concentrations, numbers of circulating lymphocytes and neutrophils and plasma glucose concentrations and were analysed using indirect pharmacokinetic/pharmacodynamic models. The cumulative systemic effect increased with dose for markers of pharmacodynamic activity. The estimated IC50 of dexamethasone for cortisol and lymphocytes for the lowest dose were 3.74 +/- 2.44 and 5.58 +/- 8.37 ng/ml, respectively and the EC50 values for neutrophils and glucose were 45.8 +/- 36.9 and 1.17 +/- 0.71 ng/ml, respectively.

Animals↗
PubMed1996

Crystal structure of a camel single-domain VH antibody fragment in complex with lysozyme.

The Camelidae is the only taxonomic family known to possess functional heavy-chain antibodies, lacking light chains. We report here the 2.5 A resolution crystal structure of a camel VH in complex with its antigen, lysozyme. Compared to human and mouse VH domains, there are no major backbone rearrangements in the VH framework. However, the architecture of the region of VH that interacts with a VL in a conventional FV is different from any previously seen. Moreover, the CDR1 region, although in sequence homologous to human CDR1, deviates fundamentally from the canonical structure. Additionally, one half of the CDR3 contacts the VH region which in conventional immunoglobulins interacts with a VL whereas the other half protrudes from the antigen binding site and penetrates deeply into the active site of lysozyme.

Amino Acid Sequence↗
PubMed1997

Phenylbutazone pharmacokinetics and bioavailability in the dromedary camel (Camelus dromedarius).

Phenylbutazone was administered intravenously and intramuscularly at a dosage rate of 4.4 mg/kg to a group of 6 female camels in a two-period crossover study. After intravenous (i.v.) administration, disposition was characterised by a two-compartment open model, with a low volume of distribution (0.174 l.kg-1), and distribution and elimination half-lives of 0.43 and 12.51 h, respectively. After intramuscular (i.m.) dosing absorption was relatively rapid with absorption half-time and time of maximal concentration values of 1.14 and 3.95 h, respectively. Plateau concentrations of phenylbutazone in plasma were obtained between 2 and 12 h and mean bioavailability was 97%, although this was subject to wide inter-animal differences. Plasma concentrations of the phenylbutazone metabolite, oxyphenbutazone, were low after iv dosing and generally undetectable after im administration, indicating that it is unlikely to contribute significantly to the pharmacological effects produced by phenylbutazone administration. An indication was obtained that phenylbutazone inhibited the ex vivo synthesis of serum thromboxane B2 (TxB2) for 24h after i.v. dosing, but this finding requires confirmation.

Animals↗
PubMed1998

Pharmacokinetics, bioavailability and dosage regimen of sulphadiazine (SDZ) in camels (Camelus dromedarius).

The pharmacokinetics of sulphadiazine (SDZ) (100 mg/kg, body weight) were investigated in six camels (Camelus dromedarius) after intravenous (i.v.) and oral (p.o.) administration. Following i.v. administration, the overall elimination rate constant (beta) was 0.029 +/- 0.001/h and the half-life (t1/2beta) was 23.14 +/- 1.06 h. The apparent volume of distribution (Vd(area)) was 0.790 +/- 0.075 L/kg and the total body clearance (ClB) was 23.29 +/- 2.50 mL/h/kg. After p.o. administration, SDZ reached a peak plasma concentration (Cmax(cal.)) of 62.93 +/- 2.79 microg/mL at a post injection time of (Tmax(cal.)) 22.98 +/- 0.83 h. The elimination half-life was 19.79 +/- 1.22 h, not significantly different from that obtained by the i.v. route. The mean absorption rate constant (Ka) was 0.056 +/- 0.002 h(-1) and the mean absorption half-life (t1/2Ka) was 12.33 +/- 0.37 h. The mean availability (F) of sulphadiazine was 88.2 +/- 6.2%. To achieve and maintain therapeutically satisfactory plasma SDZ levels of > or = 50 microg/mL, the priming and maintenance doses would be 80 mg/kg and 40 mg/kg intravenously and 90 mg/kg and 45 mg/kg orally, respectively, to be repeated at 24 h intervals.

Animals↗