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PubMed1976

Scleroma of the nose and pharynx.

Scleroma of the respiratory tract was first recognized just over a century ago. The disease is endemic in a number of North African, Central American and Latin American countries. However, it has been only rarely seen in the United States. The progression of scleroma takes place through three stages. The first stage of rhinitis has an early catarrhal phase which progresses to one of atrophic rhinitis. The second stage is seen as a proliferative granulomatous growth which obliterates the nasal fossae. The third cicatricial stage is usually accompanied by pronounced scarring and retraction of the tissues involved. Because of the increased ease of international travel by both sea and air, more cases can be expected to occur in the United States. This paper is presented to alert physicians to suspect scleroma in any case of granulomatous disease of the respiratory tract.

Adolescent↗
PubMed1993

Scleroma in Uganda: a review of 85 cases.

Biopsy and autopsy protocols revealed that between 1972 and 1981, 85 cases of scleroma were diagnosed in Uganda. The disease was found to affect females more than males, and was found to be more common in the middle aged. Scleroma occurred in the nose in 96% of cases and presented commonly at a late stage. The disease was found commonly among the tribes of south western Uganda and Itesot in the east. Possible factors associated with the distribution of this disease in Uganda are discussed.

Adolescent↗
PubMed1977

[Neutrophil damage index (NDI test) and leukocytosis response in the diagnosis of scleroma].

Clinical, bacteriologica and serological study was carried out in 57 patients with various forms of scleroma. In the same patients and also in 35 donors and 10 persons suffering from other ENT diseases a study was made of the allergy test (the NDI test) and the leukocytolysis test. Various microbial preparations were approbated, specificity of phenolen was studied. A possibility of using the mentioned allergy test in the capacity of an auxillary method in laboratory diagnosis of scleroma was demonstrated.

Humans↗