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At least 685 records · Page 38Linked to original sources
PubMed2004

[Clinical and serologic research in toxoplasmic uveitis in children].

PURPOSE: We have done a retrospective study of juvenile toxoplasmic uveitis cases hospitalized between 1993-2002. MATERIAL AND METHOD: 96 juvenile uveitis were available and 21 cases were diagnosed with juvenile toxoplasmic uveitis. RESULTS: In this study we have analyzed the distribution of cases per year, each of them was investigated by functional and objective ocular examinations, laboratory tests and treatment.

Adolescent↗
PubMed2001

[Interest in treatment with subconjunctival clindamycin in toxoplasmic retinochoroiditis].

UNLABELLED: To demonstrate advantages of using subconjunctival injections of clindamycin in the treatment of toxoplasmic retinchoroiditis. METHODS: A prospective study was conducted in 13 patients with unilateral toxoplasmic retinochoroiditis. All cases were treated with subconjunctival injections of clindamycin in association with general corticosteroïds. Mean follow-up was 7.6 months. RESULTS: Subjective improvement of the visual acuity was obtained in 67% during the first week. Cicatrization was obtained in 1.4 months on average. Recurrences were developed in 15% of cases. Clindamycin did not produce any general side effects, however a conjunctival inflammation and keratitis were observed in one case caused by an error in concentration of clindamycin. Subconjunctival injections of clindamycin provide an interesting alternative in the choice of antitoxoplasmic ocular therapy.

Adolescent↗
PubMed1994

Retinochoroiditis in the acquired immune deficiency syndrome. Findings in consecutive post-mortem examinations.

A number of opportunistic agents may cause retinitis or retinochoroiditis in patients with the acquired immunodeficiency syndrome. Minimal consecutive data is available on the histopathologically confirmed prevalence of these ocular infections. A total of 48 consecutive patients with acquired immunodeficiency syndrome-related death underwent autopsy and had their eyes submitted for histopathological examination. Conventional light microscopy combined with immunohistochemistry revealed cytomegalovirus retinitis in 15 patients, toxoplasma gonddi retinochoroiditis in 3 patients and mycobacterial choroiditis in one individual with some infections being coexistent. Clinical examination prior to death was highly accurate in detecting cytomegalovirus retinitis, but failed to determine all non-cytomegalovirus causes of retinochoroiditis. Ten of 15 patients with cytomegalovirus retinitis had associated non-cular cytomegalovirus infections, most often in the brain and adrenals. After clinical detection of cytomegalovirus retinitis the median survival time was 5.5 months, not adversely affected by additional non-ocular cytomegalovirus infection.

AIDS-Related Opportunistic Infections↗
PubMed1979

Posterior segment involvement in selected pediatric infectious diseases.

This paper reviews the ocular manifestations that may be found primarily in the posterior segment of the eye in selected infectious diseases. These diseases largely affect the pediatric population. Each disease is discussed in terms of its etiology, epidemiology, clinical course and manifestations, ocular involvement, and treatment. These diseases are important since their ocular involvement may lead to severe visual impairment.

Child↗
PubMed1999

Ocular disease in AIDS.

Explore the source record for details and available documents.

AIDS-Related Opportunistic Infections↗
PubMedDate not supplied

Toxoplasmic retinochoroiditis and hydrocephalus.

A child presenting with hydrocephalus with extensive inactive retinochoroiditis and his mother with a healed toxoplasmic scar is being discussed. Maternal ocular examination in each case of hydrocephalus is recommended, as uveitis work up of the child is often unrewarding.

Chorioretinitis↗
PubMed1992

Human immunodeficiency virus and opportunistic ocular infections.

Opportunistic ocular infections are a common and important complication of the acquired immunodeficiency syndrome. Cytomegalovirus retinitis is by far the most frequent infection, but other viral, bacterial, and parasitic infections of the posterior segment of the eye may be seen. Infections of the anterior segment are less common but may cause visual loss if not treated. Prompt recognition of these diseases is essential because ocular involvement may be an early sign of systemic dissemination.

AIDS-Related Opportunistic Infections↗
PubMed1983

Retinal disorders of childhood.

Included in this discussion of retinal disorders affecting infants and children are retrolental fibroplasia, diabetic retinopathy, sickle cell retinopathy, retinal detachment, retinal hemorrhages of neonates, macular disease, colobomas, ocular toxocariasis, and TORCH syndrome.

Anemia, Sickle Cell↗
PubMed1971

Effects of an interferon inducer, poly I:C, on acute ocular infection produced by intracameral inoculation of Toxoplasma gondii.

A potent interferon inducer, synthetic polyinosinic acid-polycytidylic acid complex (poly I:C), was used prophylactically and therapeutically in experimental ocular Toxoplasma infections in rabbits. Daily intravenous injections of poly I:C alone or when combined with daily subconjunctival injections of the inducer delayed the appearance of conjunctivitis, corneal opacity, and iritis in Toxoplasma-infected eyes provided that the treatment was started 1 day before the infection. When the treatment was begun at the same time or 1 day after the infection, no delay in the production of the ocular lesions was noted. In no case was the treatment curative or completely suppressive.

Animals↗
PubMed1992

[Ocular complications of AIDS. Diagnostic problems].

Presentation is made of the ocular complications of AIDS which were observed in the ophthalmologic clinic of the University Hospital in Zurich from 1986 to 1991. Besides cotton-wool spots, CMV-retinitis is the most frequent and best known infectious complication. In all other infections, diagnosis is most difficult, because it could never be supported by histological examination. Presentation is made of some cases of acute retinal necrosis, toxoplasmosis, cryptococcosis, candida, and of some cases of uveitis with unknown etiology. Furthermore we present one intraocular non-Hodgkin lymphoma, some suspicions of Kaposi's sarcoma and some neurologic disturbances of central origin.

Acquired Immunodeficiency Syndrome↗
PubMed1990

Unusual ocular lesions in AIDS.

Presentation of 5 patients with acquired immune deficiency syndrome and unusual ocular complications. The first case appears as a non-specific, intermediate uveitis, the others as complications due to various infectious agents.

Acquired Immunodeficiency Syndrome↗
PubMed1975

Cooperative clinical trials. The Second Ticho Memorial Lecture.

As exemplified by the collaborative Diabetic Retinopathy Study, all the appropriate techniques involved in a clinical trial-random assignment of treatment, appropriate controls, and avoidance of investigator bias-should be incorporated during the earliest testing of a new therapy for a chronic disease, for the sake of the patient and for the progress of medical science. This approach to clinical trials in the testing of new ocular therapies can provide the most scientifically sound and rational therapy to the patient.

Aged↗
PubMed1985

Secondary Fuchs's heterochromic cyclitis: a new approach to an old disease.

A study of 17 cases of Fuchs's heterochromia. Among these patients 10 had chorioretinal scar. In 3 cases the disease was seen after chronic cyclitis in a case after traumatism. Fuchs's heterochromia seems be in almost all cases a secondary disease. We do not know how a primary ocular disease can lead to Fuchs's syndrome. it is possible that this mechanism is autoimmune.

Adolescent↗
PubMedDate not supplied

Immunology of chorioretinal disorders.

Because of its uniqueness, the eye has long been a favored site for immunological study. It is a highly active tissue immunologically, with virtually all types of immune reactions present. This article reviews the ocular immune response, chorioretinal diseases with immunologic features, and immunology of ocular tumors. Immunologic data is discussed as it relates to the pathogenesis, clinical features, and therapy of chorioretinal disease.

Animals↗
PubMed1985

Congenital toxoplasmic retinochoroiditis in the mouse--the use of the peroxidase anti-peroxidase method to demonstrate Toxoplasma antigen.

The peroxidase anti-peroxidase immunocytochemical staining method has been used to demonstrate Toxoplasma antigen within paraffin-embedded sections of the eyes of mice congenitally infected with Toxoplasma. Intact Toxoplasma tissue cysts were demonstrated within the retina but in no other ocular structure. No endozoites and no extra-cystic antigens were detected by this technique within any of the eyes examined. The possible implications of these findings in relation to the pathogenesis of toxoplasmic retinochoroiditis are discussed.

Animals↗