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At least 703 records · Page 39Linked to original sources
PubMed1990

Direct observation of sexual competition in Drosophila melanogaster: the mutant white in competition with other genotypes.

When two types of Drosophila are in competition, the frequency dependence of mating success routinely is measured in our laboratory by direct observation of mating pairs in "Elens-Wattiaux" observation chambers. The present experiments concern white mutants (used here as a reference standard) in competition with three other genotypes: wild-type Canton S, "giant" gt wa, and "giant" gt13z/w+ Y/C(1)Dx, y f. From the present observations, the frequency dependence of mating success seems a very common phenomenon: a rare-type sexual advantage exists for females and for males. Sexual activity of male and female white mutants is significantly higher when food is present in the mating chamber. Males of the other strains also are more active in the presence of food. Homogamic matings are more frequent among gt13z/w+ Y/C(1)Dx, y f flies.

Animals↗
PubMed1977

A psychological theory of child abuse.

This paper presents a detailed study of two patients hospitalized in a closed psychiatric unit on which the treatment program emphasized dynamically oriented individual psychotherapy and family therapy. The first patient was hospitalized following physical abuse of her four-year-old daughter, while the second was hospitalized for a postpartum depression eight weeks following the birth of her first child, a girl. Although the presenting pictures in these two patients were markedly different, the psychodynamic patterns were so similar that a detailed comparison of the two cases seems to offer useful insight into some of the psychological causes of child abuse.

Adult↗
PubMed1992

Theory change in immunology. Part I: Extended theories and scientific progress.

This two-part article examines the competition between the clonal selection theory and the instructive theory of the immune response from 1957-1967. In Part I the concept of a temporally 'extended theory' is introduced, which requires attention to the hitherto largely ignored issue of theory individuation. Factors which influence the acceptability of such an extended theory at different temporal points are also embedded in a Bayesian framework, which is shown to provide a rational account of belief change in science. In Part II these factors, as elaborated in the Bayesian framework, are applied to the case of the success of the clonal selection theory and the failure of the instructive theory.

Allergy and Immunology↗
PubMed1983

Coronary heart disease risk factors in bus and truck drivers. A controlled cohort study.

Fifty-two bus and truck drivers and a control group of 52 male industrial workers were studied with regard to risk factors for coronary heart disease (CHD) as well as some psycho-social and occupational indicators. The main results were: higher mean values for serum cholesterol, serum triglycerides and blood pressure in the driver group, indicating a markedly higher risk of CHD in the driver group. The two groups were matched for age, socio-economic status, dietary habits, smoking habits and alcohol consumption. In the study the groups were found to be equal as regards CHD-inheritance, physical activity in leisure time, and relative body weight, W/H2. No CO could be traced in the vehicles. The psycho-social and occupational indicators showed considerable differences. The average score for the exposure factor "tempo/time-limit/urgency in job" was 50% higher, and the number of persons with the characteristic "type-A coronary-prone behaviour" was 30% higher in the driver group than in the control group. The difference in blood lipids and blood pressure increased with age. It is suggested that the higher CHD-risk in the driver group is associated with two factors: (1) greater psychic pressure in the working situation; (2) the selection of more type-A persons to driver occupations. A probable, but not commonly accepted theory, is that these psychosocial indicators may influence the traditional risk factors in a harmful way.

Adult↗
PubMed1990

Competition for sucrose-pellets in triads of male Wistar rats: effects of acute and subchronic chlordiazepoxide.

Within triads of male Wistar rats, some animals almost completely abstain from competition for palatable sucrose pellets (so-called poor-performing rats), whereas other rats consistently win the competition (so-called high-performing rats). Subchronic (5 mg/kg; 5 consecutive days), but not acute (0.1-20 mg/kg), treatment with chlordiazepoxide temporarily helped poor-performing rats to behave more competitively. This finding, considered together with parallel studies (using high-performing rats), suggested that chlordiazepoxide's beneficial effect was only demonstrable when the poor-performing rats had become tolerant to the drug's initial sedative effect.

Animals↗
PubMed1990

8-OH-DPAT specifically enhances feeding behaviour in mice: evidence from behavioural competition.

The behavioural specificity of the hyperphagic effects of 8-OH-DPAT is a controversial issue. The present study addressed this question through the introduction of behavioural competition. Feeding behaviour in male mice was assessed under both basal (free-feeding) and social conflict conditions. Since, in the latter condition, defence and escape are prepotent responses, elicitation of feeding would be indicative of a specific treatment effect on mechanisms controlling food intake. Results showed that 8-OH-DPAT enhanced basal feeding duration (at doses of 0.05-0.50 mg/kg) and also elicited feeding in intruder mice during encounters with aggressive resident conspecifics (at doses of 0.10-0.50 mg/kg). As the 5-HT3 antagonist GR38032F (1.0-2.0 mg/kg) enhanced feeding only under basal conditions, the effect of 8-OH-DPAT cannot readily be attributed to anxiety reduction. Finally, diazepam (1.0-2.0 mg/kg) produced a similar profile to that of 8-OH-DPAT, suggesting that the hyperphagic effects of the 5-HT1A agonist are not pharmacologically specific.

8-Hydroxy-2-(di-n-propylamino)tetralin↗
PubMed1996

Psychiatrists as treatment team leaders: pitfalls and rewards.

The multidisciplinary treatment team has become a conventional component of inpatient psychiatric care delivery. Treatment team dynamics and their implications for the patient, the team members, the organization, and the team leader in particular have been generally understated in the training of psychiatrists, however, as has its value as a model for learning about administration. This article highlights the history and evolution of the multidisciplinary treatment team in psychiatry, the mix of mental health disciplines, philosophies, and roles involved, the characteristics of mental health care professionals, the conflicting manifest and latent work group tasks, and the dynamics and functions of team leadership. While reviewing information on which to base a systematic approach to team leadership, the author advocates for application of universal standards for education in administrative psychiatry including supervised leadership of multidisciplinary treatment teams and discussions of complimentary readings, examples of which are provided.

Competitive Behavior↗
PubMed1995

Childhood hyperactivity scores are highly heritable and show sibling competition effects: twin study evidence.

Hyperactivity has consistently been shown to be familial. Until recently however, due to a lack of systematic twin evidence, it has remained uncertain to what extent familial transmission can be explained by genetic factors. We used a systematically ascertained population-based sample of twin pairs aged between 8 and 16 years old to explore the role of genetic influences on maternally rated hyperactivity scores. Hyperactivity scores were found to be substantially heritable. The data were best explained by a model which incorporated sibling competitive effects as well as additive genetic factors. These findings suggest not only that hyperactivity scores are influenced by genetic factors but that sibling interaction effects are also of importance.

Adolescent↗