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Dacryology in China.

PURPOSE: International Society of Dacryology held the IV International Congress in Stockholm on June 1996. I was warmly invited as a guest of honor beforehand to deliver a lecture on a special topic of "Dacryology in China" there, so that the world might understand the dacryology in China, and thus the international growth of dacryology as a discipline would be promoted. METHODS: In China tear lab research and clinical research of LG are nearly empty except a few papers published. We had studied 3 items on LS for 28 years before 1979, and put our attention mainly on dacryology since 1979 by 3 stages: (1) collecting literatures (1979-81); (2) lab research (1981-84) and (3) clinical research, put DE as the key point by 4 steps: DE diagnosis (1984-86); DE treatment (1987-91); DE Condition Judgement (1989-92) & DE cause & mechanism (1991-95). RESULTS: In the past 44 years, esp. from 1979 on, in a planned way, we have systematically researched the dacryology with main results below: created new word "Leiyexue" in Chinese & its English words, dacryology & lacrimology by adding-ology to dacrya & lacrima; made LS consisted of reflex LG & LP, and basic LG besides; found out the normal & abnormal data of tear and serum LF & its iron bindingcapacity; MDH, LDH & isoenzymes; beta 2 m; MDA & antioxidants; trace elements, prostaglandins, intramuscular gentamicin passing the blood-tear barrier; bacteria, fungi, anaerobe, virus & parasite; Ig, T cell & subsets, Langerhan cell, HLA antigen; in cidence (KCS, 0.3-3%, trancomatous DE 0.003%); the parallel correlations between DE graded by rb, BUT & Slt; and in SS, lymphocytes infiltration in LG; Lab G & conjunctiva; LF (< 100 mg%) & beta 2 m (> 1.7 mg%); and testosterone receptors in LG; negated presence of tear Beta-lysim; set up a series of models for researching & a complete set of measures to diagnose, grade, judge and treat DE, deviced new operations. AT & prescription for DE; proved SS being autoimmune & EB virus, its one cause. CONCLUSIONS: This relatively, overall & systematical research of dacryology already have been widely applied to practice with over 100 papers published. It indicates that LS & its disease as a scientific discipline under the term of dacryology to grow up is entirely possible and extremely needful.

Animals↗

[Surgical treatment of lesions of the lacrimal caruncle].

Each lesion which produces a prolong change of the volume of the caruncle necessitates surgical treatment, removal of the caruncle. Caruncular lesions are uncommon. During 15 years on the Institute for eye diseases in Belgrade authors have treated 121 caruncular lesions. Here they present their way of surgical treatment of the caruncle and point out some problems connect with this procedure.

Humans↗

Histological examination of the lacrimal gland after experimental administration of Cladribine.

The experiment was carried out on female rabbits of New Zealand breed weighing about 3 kg. The rabbits from experimental group I received Cladribine in the dose corresponding to the schema of treatment in the hairy cell leukemia and the animals from the experimental group II the dose corresponding to the experimental treatment in multiple sclerosis. The lacrimal glands were collected for histological examinations in the light microscope. It was observed that administration of Cladribine in the dose corresponding to the therapeutic dose used in the therapy of hairy cell leukemia could have caused morphological changes in the lacrimal gland, but the medicine administered in therapeutic doses in experimental therapy of multiple sclerosis does not cause morphological changes in the structure of the lacrimal gland on the level of the light microscope.

Animals↗

[ Ulcerated adenoid cystic carcinoma of the lacrimal gland--case presentation].

The authors present the case of a 63 years old patient, admitted in the Neurosurgical Department, presenting exulcerated adenoid cystic carcinoma of the right lacrimal gland. The tumor was extended medially to the superolateral part of the posterior orbit and laterally in the temporal fossa. The patient presents one and a half years history of left exophthalmos, the tumor exulcerated in the left temporal region one year ago, meantime the tumor extended in the superior half of the posterior orbit. The tumor was completely removed using superolateral orbital approach, with very good postoperative course. Complete recovery of the visual function and satisfactory aesthetic aspect was obtained, without the risks of a craniotomy. Good outcome without recurrence in the past two years.

Carcinoma, Adenoid Cystic↗

Histopathological classification of 272 primary epithelial tumors of the lacrimal gland.

272 primary epithelial gland tumors were classified pathologically. These tumors were sampled from 70% of 390 lacrimal fossa lesions out of 1530 orbital tumors from one hospital. Benign mixed tumors ranked the first in frequency (52%) to be followed by adenocystic carcinomas (25%) and malignant mixed tumors (9%). From the other less common tumor types, we identified, for the first time 3 polymorphous low-grade adenocarcinomas, 2 spindle celled myoepitheliomas and one carcinosarcoma of the lacrimal gland. The diagnosis and differential diagnosis of polymorphous low-grade adenocarcinoma and spindle cell myoepithelioma were discussed.

Adenocarcinoma↗