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At least 703 records · Page 39Linked to original sources
PubMed1983

[Experience in using the small PMB-6E betatron for the radiation treatment of oncological patients].

The paper is concerned with the first results of treatment of 46 patients with tumors of the skin, oral mucosa and other sites using the Soviet small-size PMB-6E betatron with the energy of fast electrons at 6 MeV. The performance of the unit and different variants of dosimetric therapeutic plans of the fast electron beam are presented. Electron therapy with the energy of 6 MeV was mostly used in patients with head and neck tumors. Intra-oral irradiation with fast electrons was given to 4 patients with cancer of the moving part of the tongue and 5 patients with cancer of the fundic oral mucosa, the soft palate and the buccal mucosa in the form of combined or concomitant therapy. Summary focal doses in irradiation with fast electrons were 45-63 Gy for a combined or radical therapeutic course. A noticeable tumor regression was observed in patients with cancer of the skin, vermilion border and breast cancer recurrences. Though there were very few cases the results of concomitant and combined radiotherapy of cancer of the oral mucosa were promising. The first results of clinical application of the small-size PMB-6E betatron have shown its high efficacy for the treatment of superficial tumors.

Adolescent↗
PubMed1994

Arterial infusion chemotherapy in far advanced cancer.

From 1978 to 1994, more than 2000 advanced cancers were treated by arterial infusion chemotherapy in the Department of Surgery, Kaohsiung Medical College Hospital. During these 16 years there are a lot of improvements in arterial therapy. The catheter changed from external catheter to implantable port catheter system. The infusion pump changed from spring driven pump to more accurate battery operated electric pump. But the principle of the higher the regional tumor drug exposure, the better the treatment result is the same. There are 3 main factors affecting the successful treatment, proper placement of the catheter, suitable selection of the drugs and adequate regional tumor blood supply. The first two factors can be improved by learning and experience. However, we can do little about the third one. The blood supply of the tumor had decided most of the outcome of the treatment. Those tumors over locations with very rich blood supply such as cancers of head, breast, external genitals and hands, always respond better to chemotherapy no matter the drugs were given regionally or systemically. Of course if the anticancer drug was administered by arterial route, very high concentration of anticancer drug can be delivered to the tumor region to induced rapid shrinkage of the tumor within a relative short time.

Adolescent↗
PubMed1993

Techniques for endoscopic and non-endoscopic intracorporeal laser applications.

This article deals with various designs of CO2 and Nd:YAG lasers currently used in surgery. It is discussed how their wavelength and beampath characteristics can be utilized in either the contact or the non-contact method to achieve specific clinical aims. These may concern endoscopic procedures, e.g. palliative tumour destruction or haemangioma or cystic membrane coagulation, or non-endoscopic procedures, as exemplified by two case reports on treatment for a congenital vascular disorder and varicosis, respectively. As there is a certain overlap of laser and high-frequency applications, their respective advantages and drawbacks are compared in detail. The main safety concern in HF surgery is that of errant currents in the patient, whereas in laser applications the main hazard is to the operators' eyes. This hazard can be safely eliminated.

Adult↗
PubMed1976

Ophthalmic manifestations of multiple endocrine neoplasia, type three.

We report the case of a patient with multiple endocrine neoplasia type three, which was first diagnosed by members of the department of Ophthalmology. He was found to have multiple mucosal neuromata and medullary thyroid carcinoma. The ocular components of this syndrome include visible corneal nerves, conjunctival neuromas, thickened lids, anterior displacement of the cilia and a "dry eye" syndrome. The major systemic components are medullary thyroid carcinoma and pheochromocytoma. It is important that the Ophthalmologist recognize the ophthalmic manifestations of this syndrome so that early diagnosis and treatment may be possible.

Adrenal Gland Neoplasms↗
PubMed1998

[Facial epitheliomas: general considerations, surgical techniques and indications].

Carcinoma of the face is the skin disease most frequently encountered by plastic surgeons in everyday practice. Although basal cell carcinomas and squamous cell carcinomas are generally easy to recognize, their treatment remains subject to various schools of thought, or even individual practices, which are often difficult to define. This article defines a general plan of management of these tumours; their histological duality corresponds to a therapeutic duality. Resection of a basal cell carcinoma requires safety margins of 3 to 4 mm, versus at least 5 mm for a squamous cell carcinoma. In a high-risk subject, with a sclerodermiform carcinoma or undifferentiated squamous cell carcinoma, this safety margin may be as much as 10 mm or more. Frozen section examination is preferable in these situations. Six anatomical regions are studied selectively to define the main rules of reconstruction: nasal region, orbitopalpebral region, labial region, malar region, frontal region and auricular region. Each region will be subdivided into several subterritories, each requiring different strategies. The objectives, methods and indications of each reconstruction are selectively defined. The final strategy proposed is based not only on the author's personal experience, but also on the results of the national survey on carcinomas. As a complement to these therapeutic guidelines, the authors raise the problem of incomplete resection, which requires the definition of a peripheral infiltration index predictive of the recurrence rate. Surgery obviously cannot constitute exclusive treatment carcinomas, hence the value of presenting other methods currently available in the therapeutic armamentarium. Surveillance is essential in every case, determined by the patient's risk of recurrence or even metastatic dissemination.

Basal Cell Carcinoma↗
PubMedDate not supplied

Plastic surgery after ablative cancer surgery.

Plastic and reconstructive surgery often is conceptualized either as "cosmetic" or as involving complex operations with massive flaps or time-consuming and difficult microsurgery. A number of personal cases are used to illustrate that reconstruction after cancer surgery, even reconstruction of some large tumors, can be performed with modern modifications of classic local flaps, but that sound knowledge and skill in basic surgical and plastic techniques are inescapable prerequisites.

Breast Neoplasms↗
PubMed1982

The surgical treatment of vascular tumours of the face.

On the basis of 650 vascular tumours of the face treated in the Hospital of Plastic Surgery in Polanica Zdrój, the authors discuss the various methods of surgery evolved during the 30 years of Centre activity. Special attention has been paid to the management of the more difficult lympho- and haemangiomas such as cavernous, hypertrophic and expansive, or progressive forms. Numerous examples of treatment are presented.

Adolescent↗
PubMed1994

Scalpel sculpturing techniques for graft revision and dermatologic surgery.

BACKGROUND: Postoperative scars can be revised by a variety of techniques, including dermabrasion, laser, curettage, razor blade, and scalpel surgery. Most modern methods of scar revision provide good results but at the expense of time and economy. OBJECTIVE: We present our scalpel sculpting technique that uses the #15 scalpel blade to microshave and feather the skin edges to equalize differences in skin elevations caused by uneven healing. The superficial wounds then heal by second intention. METHODS: Sculpting techniques were used to revise side-to-side closures (grafts and flaps), trap-door elevations, standing tricones and hypertrophic scars. In addition, we used the sculpting technique to remove superficial blemishes such as actinic and seborrheic keratoses, skin tags, and other benign lesions. RESULTS: We have used scalpel sculpting techniques to revise scars and remove blemishes for more than 5 years. We have removed thousands of skin imperfections with very gratifying results. CONCLUSION: Scalpel sculpting techniques provide a simple, efficient method of scar revision and removal of superficial skin lesions. The technique reduces operative time and streamlines instrument reprocessing. Because of its simplicity, there is a high degree of patient, nursing, and physician satisfaction.

Aged↗
PubMed1990

Cutaneous malignant fibrous histiocytoma. A rare but serious malignancy.

We report 3 cases of malignant fibrous histiocytoma occurring as primary neoplasms of the skin. The first case developed in a leg ulcer of traumatic origin. The second developed on the lower lip at the site of a squamous cell carcinoma which had been treated by radiotherapy. The third arose on a calf at a site of previous surgery. The literature on this malignancy is reviewed, with emphasis on cutaneous involvement.

Aged↗
PubMed1981

Unusual appearances of cancers in the skin.

Markedly unusual appearances of cutaneous cancers are uncommon, but they deserve comment upon for reasons other than their appearances. Ten unusual cases are illustrated and briefly commented upon.

Aged↗
PubMed1997

Absence of latent Epstein-Barr virus in cutaneous squamoproliferative lesions after solid organ transplantation.

Recent studies implicate Epstein-Barr virus (EBV) in the pathogenesis of an increasing number of lymphoid and epithelial tumors. EBV-related disorders are particularly prevalent in immunosuppressed patients. The most common neoplasms arising in persons receiving long-term immunosuppressive agents after organ transplantation include non-Hodgkin's lymphomas and skin and lip carcinomas. Because EBV plays a major role in the evolution of post-transplantation lymphoproliferative disorders and was recently identified in a squamous cell carcinoma of the lip in a renal transplant recipient, we examined squamoproliferative lesions of the skin and lips for the presence of latent EBV. Twenty-six paraffin-embedded specimens from 23 different squamoproliferative lesions occurring in 9 solid organ transplant recipients were examined for the presence of latent EBV by in situ hybridization for EBV-encoded small RNA (EBER-1). The squamoproliferative lesions included 16 squamous cell carcinomas, 3 re-excisions of squamous cell carcinomas, 5 basal cell carcinomas, and 2 actinic keratoses. Two lesions from a single patient exhibited clusters of positive dermal lymphocytes after in situ hybridization with the EBER-1 probe. This patient is currently without clinical evidence of a lymphoproliferative disorder 2 years after the first biopsy showing this phenomenon. The squamoproliferative lesions were all uniformly negative. EBV does not seem to play a role in the initiation or progression of the majority of cutaneous squamoproliferative lesions arising in immunosuppressed patients who received solid organ transplants.

Adult↗