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PubMed1960

The distribution of 5-hydroxytryptamine and adenosinetriphosphate in cytoplasmic particles of the dog's small intestine.

The distribution of 5-hydroxytryptamine, adenosinetriphosphate, and succinic dehydrogenase in sucrose homogenates of the dog's small intestine has been studied. The adenosinetriphosphate was present in two different layers which could be separated by density gradient centrifugation. The upper layer contained also much succinic dehydrogenase, but no amine; it is probably composed of mitochondria. The lower layer contained not only adenosinetriphosphate but also the major portion of the particle-held 5-hydroxytryptamine. The mean molar ratio, amine: adenosinetriphosphate, in the lower layer was 2.6. The experiments suggest that adenosinetriphosphate in the intestine is of importance in the storage of 5-hydroxytryptamine, resembling the function of adenosinetriphosphate in the storage of the catechol amines of the adrenal medulla.

Adenine Nucleotides↗
PubMed1960

Cytochemical adenosine triphosphatase of vorticellid myonemes.

A highly specific adenosine triphosphatase has been found to be localized in the contractile apparatus of vorticellids. It is most prominent in the cilia as well as in the myonemes which course the latitudes and longitudes of the cell and spiral in the flat peristome. The stalk displays more activity in the spasmoneme sheath than in the spasmoneme itself. The spasmoneme canal appears negative. A delicate fiber coils around the outside of the stalk in a helix. All these structures may be seen in the living protozoan by phasecontrast microscopy.

Adenine Nucleotides↗