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Allergic contact dermatitis to colophony included in the formulation of flexible collodion BP, the vehicle of a salicylic and lactic acid wart paint.

The authors describe two cases of allergic contact dermatitis to colophony included in the formulation of flexible collodion BP, the vehicle of a wart paint. Patch and repeated open application tests confirmed absence of contact allergy to other constituents. The patients were known to be allergic to various adhesive plasters. The use of flexible collodion USP, which does not contain colophony, is highly advisable whenever possible.

Adult↗

[Studies of D-penicillamine (4) : effects on antibody formation (author's transl)].

The value of D-penicillamine (D-PA) in the treatment of rheumatoid arthritis is now well established, however, the mode of action remains obscure. We studied the effects of D-PA on the primary and secondary homocytotropic antibody formation with various doses, timing, quantity of antigen stimuli and stress loading in mice. Homocytotropic antibody was assayed by rat PCA (IgE) or mouse PCA (IgG1), and the effects were compared with those of the other antirheumatic drugs such as aurothiomalate and chloroquine diphosphate and the immunosuppressive agents such as hydrocortisone and cyclophosphamide. The antibody formation was slightly suppressed by D-PA under various conditions induced by different quantities of antigen stimuli, while the effects of the other antirheumatic drugs and the immunosuppressive agents on the primary and secondary responses differed from that of D-PA. Stress loading applied with oral consecutive administration of saline for 3 weeks or by restraint with adhesive plaster from 3 days before the primary immunization reduced the antibody formation. D-PA restored the reduced IgE antibody formation after the secondary immunization and also weight of the spleen. These observations suggest that D-PA acts as an immunomodulating agent as the spleen weight and IgE antibody formation were recovered under conditions of induced stress.

Animals↗

Nerve blocking of the sciatic and femoral nerves. Continual block with vein catheter on 44 patients.

The accessibility of the sciatic nerve from three directions (anterior, lateral and posterior) has prevented many patients from being moved, especially those who would be endangered by a change of position. A vein catheter is introduced in accordance with the approved technique up to the selected point. The stylus is withdrawn, the catheter is fixed on the skin by a suture or adhesive plaster, and by the use of a precisely fitting syringe the chosen local anesthetic solution is perfused. By this technique we can reblock the patient.

Anesthetics, Local↗

Individual skin care during radiation therapy.

BACKGROUND: In many clinical settings, the irradiated patient feels additional discomfort by the inhibition of washing the treatment portals and interruption of his adapted skin care habits. MATERIAL AND METHODS: An analysis of the scientific recommendations as well as an analysis of the skin dose to the irradiated portals has been performed. An individual scheme for skin care under radiation has been developed. RESULTS: A substantial decrease of the skin dose is achieved in many modern radiation techniques. The consequent reduction of severe skin reactions allowed the use of water and mild soaps as has been approved within many radiotherapy departments. This has lead to an individualized concept for skin care under radiation treatment including the allowance of gentle washing. The skin marks may be saved by using highly tolerable adhesive plasters or small tattoo points, if they are not superfluous by using masks or single referee points instead of marks for the field borders. CONCLUSIONS: The individualized concept for skin care during radiation may offer improved life quality to the patient and may decrease the acute reactions of the skin at least in some cases.

Baths↗

Herbal remedies improve the strength of repairing ligament in a rat model.

Herbal remedies have been reported to be effective in controlling inflammation for acute soft tissue injuries. There exist, however, no reports of their effects on collagen production and remodeling; thus mechanical strength studies of the tissues have not been reported. This study tested the effects of a herbal remedy on the strength of healing medial collateral ligaments (MCL) in rats. Sixteen rats receiving surgical transection to their right MCLs and eight receiving sham operation were tested. Eight of the MCL-injured animals were treated with an adhesive herbal plaster application to their right knees, while the other eight in the MCL injured group and the sham group were treated with plain adhesive plaster to their right knees. The MCLs were harvested and tested at either 3 or 6 weeks post-operation. The ultimate tensile strength (UTS) and stiffness normalized to the uninjured side of each animal of the herb and sham groups were significantly larger than those of the control at both 3 and 6 weeks (p = 0.001). No significant difference was found in stiffness between the herb and sham groups (p > 0.05). We concluded that the herbal remedy improves the UTS and stiffness of repairing MCLs at 3 and 6 weeks after injury.

Animals↗

Management and rehabilitation of ligamentous injuries to the ankle.

The management of ligamentous injuries to the ankle is controversial. Neither the methods for classification and diagnosis, or the procedures for treatment are clear cut. Ankle sprains are a common occurrence, with the majority involving the lateral ligament complex. Within this complex, the anterior talofibular ligament is injured most frequently, usually while the foot is in the plantar flexed position. Ankle injuries can be diagnosed through physical exam, including the anterior drawer test and/or a stress exam, or through roentgenographic evaluation. The purpose of the stress roentgenogram is to measure the degree of talar tilt. However, it does not always yield consistent, reliable results. This inconsistency has led to the use of arthrography. There is debate over its use as well, however, Ankle sprains can be classified into three groups, according to functional loss. Treatment for first and second degree sprains is usually non-operative. The best approach to Grade III sprains is debatable. The issues in the treatment of Grade III sprains are first, whether treatment should be operative or non-operative, and second, whether non-operative treatment should emphasise immobilisation or mobilisation. Brostrom's work is cited as noteworthy. He recommended adhesive strapping followed by mobilisation as the treatment of choice, and reserves surgery for cases of chronic instability. Results demonstrated that strapping yielded shorter disability periods, while surgery produced less instability. The prevention of functional instability is a major concern in the treatment of ankle injuries. There is no consensus for treating a lateral ligament rupture. The authors suggest immobilisation followed by a rehabilitative programme. Three methods of immobilisation are plaster casting, adhesive strapping, and the air-stirrup. The physiological mechanism of cryotherapy and thermotherapy are discussed briefly and recommendations for their use are provided. Aspiration is also discussed. Loss of motion is designated as a primary cause of chronic pain and reinjury, and exercises intended to restore range of motion are provided. Exercises aimed at restoring strength and proprioception are also presented. This allows for return to activity and serves to prevent reinjury.

Ankle Injuries↗

Allergic contact dermatitis to a sanitary pad.

A 13-year-old girl presented with a recurring vulval dermatitis that started several days after first using a sanitary pad. The rash settled but recurred with subsequent use of the same sanitary pads. Patch testing revealed a marked sensitivity (3+) to colophony (rosin). She denied previous reactions to adhesive tape/sticking plaster. During patch testing she also developed reactions to a black permanent waterproof marking pen used to mark the site of patch tests. The ink of this pen also contained colophony.

Adolescent↗

Applications of biopolymers and other biotechnological products in building materials.

Bio admixtures are functional molecules used in building products to optimize material properties. They include natural or modified biopolymers, biotechnological and biodegradable products. Concrete and dry-mix mortars (e.g. wall plasters or tile adhesives) represent two major applications for bio admixtures. Examples of bio products used in concrete are lignosulfonate, sodium gluconate, pine root extract, protein hydrolysates and Welan gum; and in dry-mix mortar methyl hydroxypropyl cellulose, hydroxypropyl starch, guar gum, tartaric acid, casein, succinoglycan and Xanthan gum. In a number of applications, bio admixtures compete well with synthetic admixtures. Sometimes, they are indispensable in the formulation of certain building products. Their market share is expected to increase because of technological advances, particularly in the field of microbial biopolymers, and because of the growing trend to use naturally based or biodegradable products in building materials.

Biopolymers↗

Clinical and radiographic appearance of congenital talipes equinovarus after successful nonoperative treatment.

Thirty-one children with 49 feet after successful nonoperative treatment for congenital talipes equinovarus (CTEV) by redressements, hypoallergic adhesive bands, and plaster casts underwent follow-up. At the follow-up, the patients ranged in age from 4.2 years to 12.3 years (average, 8.3 years). The initial type of the deformity was as follows: type I (mild), 18 feet; type II (intermediate), 29 feet; type III (severe), two feet. Mild supination of the forefoot in five feet, isolated excavation in three, and adduction greater than physiological in two feet were the only persistent elements of the deformity. The lack or restriction of the dorsal flexion in the ankle were noted in 22 feet. In only three feet was the Beatson-Pearson index was < 40 degrees. In 17 feet, the radiographs revealed full talonavicular reduction in sagittal and horizontal planes. The average value of the talometatarsal first and tibiocalcaneal angles as in accordance with the standard. The most characteristic osseous disturbances concerned the tarsal navicular (22 feet) and consisted of the decrease of the ossification center, its flattening, fragmentation, cystic-like changes, and wedging.

Casts, Surgical↗