PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “AORTIC STENOSIS”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 73 records · Page 4Linked to original sources
PubMed1991

[A surgical experience of aortoventriculoplasty (Konno's procedure) for aortic stenosis associated with hypoplasia of aortic valve ring progressed after the repair of supravalvular aortic stenosis].

A 14-year-old boy with aortic stenosis associated with hypoplasia of aortic valve ring underwent aortoventriculoplasty (Konno's procedure) successfully nine years after the repair of supravalvular aortic stenosis. His aortic annulus diameter before enlargement was 17 to 18 mm and after the procedure, a 25 mm St. Jude Medical prosthetic valve was implanted. It was adequate size for this large-sized student (173 cm in height, 67 kg in weight). After this operation, mild stenosis of right ventricular outflow tract was presented probably due to insufficient reconstruction of right ventricular outflow for such a dramatic enlargement of aortic annulus. Although this procedure makes possible to implant more than three-size larger prosthetic valve without major complications, we have to be careful about preventing right ventricular outflow tract stenosis in case of requiring enlargement over 40 or 50% of aortic annular circle.

Adolescent↗
PubMed1996

Management of pediatric patients with isolated valvar aortic stenosis by balloon aortic valvuloplasty.

Moderate to severe aortic stenosis in children requires an initial procedure to improve the stenosis and often additional procedures for recurrent stenosis or aortic insufficiency before adulthood. The purpose of this study was to evaluate children who underwent balloon valvuloplasty and were followed with a specific management plan. Twenty-two children with aortic stenosis underwent balloon valvuloplasty and were followed on a regular basis. Repeat valvuloplasty was performed if indicated. The initial gradient was reduced from 63 +/- 9 mmHg to 28 +/- 8 mmHg (P < 0.001). There were no deaths and only one major complication, which had no sequelae. Average follow-up was 61 +/- 23 months. Three patients required valve replacement 39-76 months after valvuloplasty for progressive insufficiency. Seven patients underwent successful repeat valvuloplasty. The overall probability of survival without surgical intervention was 75% at 100 months. Balloon valvuloplasty is an effective intermediate palliation for aortic stenosis and is an acceptable alternative to surgical valvotomy. Repeat valvuloplasty is successful without additional risk. In a subgroup of patients, aortic insufficiency is progressive and will require surgical intervention.

Adolescent↗
PubMed1988

Pivotal role of aortic valve area calculation by the continuity equation for Doppler assessment of aortic stenosis in patients with combined aortic stenosis and regurgitation.

Aortic regurgitation (AR) may result in overestimation of the aortic pressure gradient by continuous wave Doppler in patients with mixed aortic valve disease. However, few data are available regarding the effect of AR on noninvasive estimates of aortic valve area by the continuity equation. Therefore, 25 patients with angiographically documented severe AR and peak systolic aortic velocities of greater than 2.5 m/s were studied by continuous wave Doppler to determine the accuracy of pressure gradient and aortic valve area calculations in assessing the severity of aortic stenosis (AS) in this patient population. Peak instantaneous pressure gradient showed a general correlation to but was overestimated by Doppler (r = 0.78, Doppler = 0.70 catheter + 19.9) and did not predict aortic valve area. Mean pressure gradient by Doppler correlated more closely with catheter mean gradient (r = 0.86, Doppler = 0.79 catheter + 6.1) but was a poor predictor of the severity of AS. In contrast, the continuity equation accurately predicted the aortic valve area by catheterization (r = 0.92, Doppler = 0.89 catheter -0.08). Thus, the continuity equation provides a reliable estimate of aortic valve area in patients with severe AR and should be used to evaluate the extent of AS in such patients when high systolic aortic velocities are present.

Aortic Valve↗
PubMed1988

Prediction of the severity of aortic stenosis by Doppler aortic valve area determination: prospective Doppler-catheterization correlation in 100 patients.

Two-dimensional and Doppler echocardiography was performed prospectively in 100 patients with aortic stenosis who were undergoing clinically indicated cardiac catheterization. The purpose of this study procedure was to determine various Doppler variables predictive of the severity of aortic stenosis and to compare Doppler- and catheterization-derived aortic valve areas. Doppler-derived mean gradient correlated well with corresponding gradient by catheterization (r = 0.86). Peak Doppler aortic flow velocity greater than or equal to 4.5 m/s and Doppler-derived mean aortic gradient greater than or equal to 50 mm Hg were specific (93 and 94%, respectively) for severe aortic stenosis (defined as catheterization-derived aortic valve area less than or equal to 0.75 cm2) but were not sensitive (44 and 48%, respectively). Doppler-derived aortic valve area calculated by the continuity equation correlated well with catheterization-derived aortic valve area calculated by the Gorlin equation when either the time-velocity integral ratio (r = 0.83) or the peak flow velocity ratio (r = 0.80) between the left ventricular outflow tract and the aortic valve was used in the continuity equation. A velocity ratio of less than or equal to 0.25 alone was sensitive (92%) in detecting severe aortic stenosis. Therefore, use of various Doppler-derived values allows reliable noninvasive estimation of the severity of aortic stenosis.

Aged↗
PubMed1975

Reversal of dominance of the coronary arterial system in isolated aortic stenosis and bicuspid aortic valve.

The dominance of the coronary arterial system was determined angiographically in 75 adult patients with isolated aortic stenosis with or without insufficiency, 25 adult patients with pure aortic insufficiency, 51 adult patients with combined aortic stenosis and mitral valve disease, and 44 children with bicuspid aortic valves. There was an unusually high incidence of left dominance in adults with isolated aortic stenosis (36%) and in children with bicuspid aortic valves (56.8%). These findings suggest the existence of a variant developmental complex consisting of a bicuspid aortic valve and reversal of dominance of the coronary arterial system. Furthermore, it adds support to the concept that progressive stenosis of a bicuspid aortic valve is frequently the etiology of isolated aortic stenosis in adults.

Adult↗
PubMed2006

[Apicoaortic conduit insertion for elderly patients with acquired aortic stenosis and small aortic annulus].

BACKGROUND: Patients with critical aortic stenosis, a heavily calcified aorta, and a small aortic annulus are at an increasing risk of complications during a conventional aortic valve replacement (AVR) procedure. Insertion of an apicoaortic conduit (AAC) can be an alternative to AVR in such situations. This study is a review of our experiences with AAC in elderly patients with acquired aortic stenosis. METHOD: From 2001 to 2005, 7 elderly patients (mean age of 81 : range 74 to 87) underwent an AAC insertion for severe symptomatic aortic stenosis with a small aortic annulus (mean annulus size 17.9 mm). Preoperatively, all were symptomatic, with 4 rated as New York Heart Association (NYHA) functional class IV, 2 as class III, and 1 as class II. In addition, 3 patients had severe congestive heart failure with mechanical ventilation and received a high dose administration of catecholamine, and 1 had undergone coronary artery bypass grafting (CABG) previously. RESULT: The AAC insertions were performed under a cardiopulmonary bypass through a left thoracotomy in 6 patients, while 1 patient underwent the procedure without a cardiopulmonary bypass. Distal anastomoses were performed in the descending thoracic aorta with a partial occluding clamp. A composite woven Dacron conduit with a stented biological valve was used in 2 cases, and a woven Dacron conduit with a stentless bioprosthesis was used in 5. Two patients underwent a concomitant CABG. There was 1 hospital death due to obstructive ileus 4 months after the operation. One patient who had been in a shock state preoperatively had hypoxic encephalopathy due to inoperative severe hypotension. Postoperative echocardiography showed relief of the left ventricle-aortic gradient in all patients. After a mean follow-up period of 22 months, there was no late death, while 3 patients were readmitted due to congestive heart failure. Further, 1 of the patients was rated as NYHA class I, 1 as class II, and 2 as class III. CONCLUSION: An AAC procedure was found to be an acceptable alternative for elderly patients who had a high-risk of complications with the standard procedure.

Aged↗