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Inequality in quality: addressing socioeconomic, racial, and ethnic disparities in health care.

Socioeconomic and racial/ethnic disparities in health care quality have been extensively documented. Recently, the elimination of disparities in health care has become the focus of a national initiative. Yet, there is little effort to monitor and address disparities in health care through organizational quality improvement. After reviewing literature on disparities in health care, we discuss the limitations in existing quality assessment for identifying and addressing these disparities. We propose 5 principles to address these disparities through modifications in quality performance measures: disparities represent a significant quality problem; current data collection efforts are inadequate to identify and address disparities; clinical performance measures should be stratified by race/ethnicity and socioeconomic position for public reporting; population-wide monitoring should incorporate adjustment for race/ethnicity and socioeconomic position; and strategies to adjust payment for race/ethnicity and socioeconomic position should be considered to reflect the known effects of both on morbidity. JAMA. 2000;283:2579-2584

Empirical Research↗

Use of participatory ergonomics teams to address musculoskeletal hazards in the red meat packing industry.

Participatory ergonomics teams from two departments of a pork slaughtering plant analyzed musculoskeletal hazards and proposed ergonomics solutions for several jobs in the plant. The jobs were targeted based on association with a large number of injuries, one or more particularly severe injuries, high workers' compensation expenses, and/or high turnover plus absence of obvious solutions to abate the hazards. The teams used a structured problem-solving method that was generally derived from principles associated with quality improvement processes. Workers performing the targeted jobs were involved in the problem-solving process, even if they were not members of the team. The effectiveness of each team was assessed and compared in terms of the number of problem jobs addressed and feedback from team members. One team addressed all nine of its targeted jobs; the other team addressed eight of 12 targeted jobs. Feedback from team members regarding their teams' methods and performance was generally favorable. The major obstacle to effective team functioning in this project was the scheduling of meetings. There were also some obstacles related to team leadership. Overall, this project demonstrated that the use of participatory ergonomics teams that rely on structured problem-solving methods are able to work effectively to address musculoskeletal hazards, especially related to the upper extremities, in the red meat packing industry.

Animals↗

The interaction of highly helical structural mutants with the NOP receptor discloses the role of the address domain of nociceptin/orphanin FQ.

Nociceptin is a heptadecapeptide whose sequence is similar to that of Dynorphin A, sharing a message domain characterized by two glycines and two aromatic residues, and a highly basic C-terminal address domain but, in spite of these similarities, displays no opioid activity. Establishing the relative importance of the message and address domains of nociceptin has so far been hampered by its extreme conformational flexibility. Here we show that mutants of this peptide, designed to increase the helical content in the address domain, can be employed to explain the mode of interaction with the NOP receptor. Nociceptin analogues in which Ala residues are substituted with aminoisobutyric acid (Aib) show a substantial increment of activity in their interaction with the NOP receptor. The increment of biological activity was attributed to the well-documented ability of Aib to induce helicity. Here we have verified this working hypothesis by a conformational investigation extended to new analogues in which the role of Aib is taken up by Leu. The NMR conformational analysis confirms that all Ala/Aib peptides as well as [Leu(7,11)]-N/OFQ-amide and [Leu(11,15)]-N/OFQ-amide mutants (N/OFQ=nociceptin/orphanin FQ) have comparable helix content in helix-promoting media. We show that the helical address domain of nociceptin can place key basic residues at an optimal distance from complementary acidic groups of the EL(2) loop of the receptor. Our structural data are used to rationalize pharmacological data which show that although [Leu(11,15)]-N/OFQ-amide has an activity comparable to those of Ala/Aib peptides, [Leu(7,11)]-N/OFQ-amide is less active than N/OFQ-amide. We hypothesize that bulky residues cannot be hosted in or near the hinge region (Thr(5)-Gly(6)-Ala(7)) without severe steric clash with the receptor. This hypothesis is also consistent with previous data on this hinge region obtained by systematic substitution of Thr, Gly, and Ala with Pro.

Models, Molecular↗

Resiliency among individuals with childhood sexual abuse and HIV: perspectives on addressing sexual trauma.

This study examined how resiliency (represented by optimism, social support, religiosity, and finding growth and meaning), within the context of perceived impact of sexual trauma and HIV-related stress, was linked to perspectives on addressing trauma among individuals (N=266) with HIV and childhood sexual abuse (CSA). Structural equation modeling analyses indicated that lower resiliency and greater HIV-related stress were related to negative feelings about addressing trauma, whereas greater resiliency and higher perceived impact of sexual trauma were associated with positive feelings about addressing trauma. Findings suggest that multiple factors influence perspectives on addressing trauma among individuals with HIV and CSA, and that resiliency might influence these attitudes.

Adaptation, Psychological↗

Addressing alcohol use among primary care patients: differences between family medicine and internal medicine residents.

OBJECTIVES: To determine whether rates of addressing alcohol use differed between family medicine and internal medicine residents, and to determine whether attitudes, confidence, and perceptions affected these relationships. SETTING: Two university outpatient clinics, one staffed by family medicine and the other by primary care and categorical internal medicine residents. DESIGN: Cross-sectional study of consecutive patients who had been followed by second- and third-year residents for at least one year. MEASUREMENTS: Alcohol abuse was determined using the Michigan Alcoholism Screening Test (MAST), with a score > or = 5 considered positive. Rates of addressing alcohol use in the preceding year were determined by patient report and chart review. Attitudes were assessed using the Substance Abuse Attitude Survey (SAAS). RESULTS: 334 patients of 49 residents completed the MAST. Rates of alcoholism among the patient groups were: family medicine, 8.3%; primary care, 29.1%; and categorical medicine, 18.0% (p < 0.001). Screening behavior varied by type of residency: 47% of the family medicine, 71% of the primary care, and 65% of the categorical residents' patients reported being asked about alcohol use in the preceding year (p < 0.001); chart documentation was present for 15% of the family medicine, 38% of the primary care, and 24% of the categorical residents' patients (p < 0.001). Perceived prevalence of alcohol abuse, confidence in intervening, and several scales on the SAAS were related to residency type and to addressing alcohol use, but controlling for these variables did not affect the association between residency type and either patient report or chart documentation of screening. CONCLUSION: Rates of addressing alcohol use differed for internal medicine and family medicine residents, but were not due to differences in resident perceptions and attitudes.

Alcoholism↗

Cognitive ergonomics of a mail order filling company: Part 2--influence of shelf coding and address information on acquisition time.

This is the second part of a study on a mail order picking task. In the first part of the study, recognition time was addressed by varying colour, position and highlighting cues in a computer-simulated version of the picking task. This study addresses the product acquisition time. Shelf coding and continuous presentation of the address information were varied in a factorial experiment in which 14 subjects (seven experts and seven novices) had participated. Experts were slower but more accurate than the novices. Continuous display of address information appears to be a good training aid for implementing new shelf coding systems, and for new operators. Shelf coding effect appears to disappear with practice. A summary of the recommendations is given.

Journal Article↗

An investigation of the accuracy of the home address given by patients in an urban community in South India.

Studies were undertaken in three tuberculosis clinics in Madras, a large Indian city with a good civic organization, to assess the accuracy of address recorded routinely by registry clerks at the patient's first clinic attendance. The accuracy was poor, with 20% to 30% of the letters posted not reaching the patients. It was appreciably improved, by 10% to 20%, by supplementing the clerk's efforts with questioning by a motivated, experienced health visitor. An address card, a card on which the patient's address was recorded by the local postman or a literate neighbour, relative or friend, was returned by 90% to 94% of the patients, and the accuracy of addresses was found to be at least as good as that obtained with the health visitor. Even when all three sources of information were considered, the patient's home could not be traced in 3% of cases and was found with difficulty in 4%.

Community Health Nursing↗

Addressing global warming and biodiversity through forest restoration and coastal wetlands creation

The Climate Challenge is a partnership between the Department of Energy and the electric utility industry to reduce, avoid, and sequester greenhouse gases. A portion of the initiative, the sequestration of greenhouse gases, is the focus of this presentation. Over 4 million acres of bottomland hardwood forests were cleared for agriculture in the Mississippi River Valley in the 1970s. Reestablishing these forests would improve depleted wildlife habitats, serve as wildlife corridors, increase biodiversity, and decrease soil erosion. Louisiana is losing coastal wetlands at a rate of approximately 25 square miles/year. This coastal erosion is due to a number of factors and many efforts are currently underway to address the matter. One such effort is the use of material generated in the dredging of navigational canals; however, this material is low in nutrient value, making the regeneration of marsh grasses more difficult. In addition, bottomland hardwood forests and coastal wetland grasses are excellent 'carbon sinks' because they take carbon dioxide out of the atmosphere and store it in living plant tissue. Entergy Services, Inc. is an electric utility with a service territory that comprises portions of both the Lower Mississippi River Valley and the Gulf of Mexico coastline. This provides an opportunity to positively address both habitat losses noted above while at the same time addressing global warming, forest fragmentation, and biodiversity. Entergy, through its affiliation with the UtiliTree Carbon Company, is participating in projects that will investigate the feasibility of using bottomland hardwood reforestation on cleared marginal farmlands now managed by the Louisiana Department of Wildlife and Fisheries and the US Fish and Wildlife Service. Entergy has also begun a research project with the Environmental Protection Agency and the State of Louisiana. The research is a compost demonstration project that will utilize wood waste generated through our tree-trimming program as a compost material that will be mixed with low nutrient dredge material to create new coastal wetlands. Taken together, Entergy's initiatives will be able to address global warming through carbon sequestration, restore fragmented forest habitats, reduce coastal erosion and improve the quality of a vital coastal aquatic nursery habitat. Efforts will be made to manage the created habitats for biodiversity. Pulling all these ideas together creates an effect in which the whole is greater than the sum of the parts. In such a synergy of ideas, there are no losers and the winners are both industry participants and the environment.

Journal Article↗

[Authors' affiliations and addresses in published articles. Lack of care penalizes French universities in international rankings].

OBJECTIVE: To assess, through the example of the université Claude Bernard Lyon 1, whether the poor international visibility of French universities may be due in part to a lack of care by researchers in listing their affiliations and address on their scientific publications. METHOD: Querying the heading "address" of Medline, Embase.com and Pascal Biomed for 2003 in searches for publications from Université Claude Bernard Lyon 1. RESULTS: In 300 bibliographic entries studied, we found 44 different forms of the university's name. Only 15% of the addresses were correct, and 44% did not mention the author's affiliation with the university. DISCUSSION: Authors' lack of care in listing their affiliations and address and the absence of a standardized official name for the university may explain the poor visibility of French universities. Recommendations about this topic might help to promote the reputation and work of French researchers internationally.

Attitude↗

Diazonium-protein adducts for graphite electrode microarrays modification: direct and addressed electrochemical immobilization.

Diazonium cation electrodeposition was investigated for the direct and electro-addressed immobilization of proteins. For the first time, this reaction was triggered directly onto diazonium-modified proteins. Screen-printed (SP) graphite electrode microarrays were studied as active support for this immobilization. A 10-microelectrode (eight working electrodes, 0.2 mm2 each; one reference; and one auxiliary) setup was used to study the addressing possibilities of the method. These electrode microarrays were shown to be able to covalently graft diazonium cations through electrochemical reduction. Cyclic voltammetry and X-ray photoelectron spectroscopy were used to characterize the electrochemical grafting onto our SP graphite surface and suggested that a diazonium monolayer was deposited. Rabbit and human immunoglobulins (IgGs) were then chemically coupled to an aniline derivative (4-carboxymethylaniline), followed by diazotation to form an aryl diazonium function available for the electrodeposition. These modified proteins were both successfully electro-addressed at the surface of the graphite electrodes without cross-talk or interference. The immuno-biochip obtained using this novel approach enabled the specific detection of anti-rabbit IgG antibodies with a detection limit of 50 fmol of protein. A promising strategy to immobilize markedly different biological entities was then presented, providing an excellent spatial specificity of the electro-addressing.

Animals↗

Role of spacer and address components in peptidomimetic delta opioid receptor antagonists related to naltrindole.

A series of heterocyclic analogues 2-5 related to naltrindole (1) (NTI) and 6-arylnaltrexone derivatives 6-8 were synthesized in order to determine the role of the spacer and the address moieties in conferring delta opioid receptor antagonist activity. The benzofuran (NTB), quinoxaline, and quinoline analogues (2, 3, and 4, respectively) were delta-selective opioid antagonists in vitro and bound selectively to delta receptors. The tetrahydroindole derivative 5, while delta-selective, was considerably less potent than its indole analogue 13. The data for 2-4 indicate that heterocycles other than pyrrole can serve as a spacer for the delta address moiety. Moreover, the lower delta antagonist potency of 5 illustrates the importance of the aromatic address component. Molecular dynamics simulations of enkephalin using a zipper binding model are consistent with a delta address subsite that may accommodate the benzene moiety of NTI or the Phe4 phenyl group of leucine enkephalin. The considerably lower delta opioid receptor antagonist potencies of the 6-aryl derivatives 6-8 are consistent with the conformational mobility of the aryl group and its location in the molecule.

Animals↗

The 'Collaborative Care' curriculum: an educational model addressing key ACGME core competencies in primary care residency training.

AIM: The 'Collaborative Care' curriculum is a 12-month senior resident class project in which one evidence-based clinical guideline is designed, implemented and evaluated in our residency practice. This curriculum specifically addresses three of the six Accreditation Council for Graduate Medical Education (ACGME) core competencies: Practice-Based Learning and Improvement, Interpersonal and Communication Skills and System-Based Practices. Additionally, the project enhances the quality of patient care within the model family practice centre in a family practice residency. METHODS: During the project, the third-year residency class selects the disease, develops the clinical guideline, leads its implementation and guides the evaluation process. Select faculty members serve as mentors and coach the resident class through each phase of the project. Specific educational objectives are developed for each content area: evidence-based medicine, clinical guideline development, continuous quality improvement and team leadership. A series of seminars are presented during the project year to provide 'just-in-time' learning for the key content and skills required for each step in the project. By working together to develop the practice guideline, then working with nurses and allied health staff to implement the guideline and review its effectiveness, the resident team gains competence in the areas of practice-based learning and improvement, interpersonal and communication skills and system-based practices. RESULTS: The self-reported level of resident confidence in skill acquisition for each content area was measured for each resident at the time of graduation from the residency programme. Results from the first 2 years of this curriculum are reported (resident n = 12), and demonstrate a high level of physician confidence in the skills addressed and their utility for future practice. CONCLUSIONS: The senior resident seminar and team project model reported here creates learning experiences that appear to address at least three of the ACGME general competency expectations: practice-based learning and improvement, interpersonal communication skills, and systems-based practice. From the initial resident feedback, this educational model seems to establish a high level of physician confidence in the skills addressed and their utility for future practice.

Clinical Competence↗

Psychiatric patients: views on psychiatrists' dress and address.

Dress styles and forms of address vary among psychiatrists according to personal preferences. Gledhill et al. (Br J Psychiatry 1997;171;228-32) asked the patients in a London psychiatric hospital about their views on their psychiatrists' dress and address. To survey the preferences of our patients and reproduce the study of Gledhill et al., we interviewed Norwegian psychiatric inpatients and outpatients to identify preferences for dress styles and terms of address. Our patients preferred fairly smart attire. Most patients wanted to be called by their first name; about half wanted to address their doctors by their first name and half by surname. Results were somewhat different from the London survey, but the conclusion is similar: paying more attention to the way psychiatrists interact and present themselves may facilitate the therapeutic alliance with their patients.

Adult↗

Patients voice issues of dress and address.

Establishing a positive patient care environment is one of the most basic concepts of health care professional practice. Dress and personal address are aspects of this environment that are influenced by culture and express mutual respect within the patient-provider relationship. The Patient Sensitivity Questionnaire was administered to determine how 76 Israeli inpatients perceived forms of address and dress in their health care environment. Patients preferred that their health care providers wear formal dress and be addressed by their formal titles. Respondents did not object to being addressed by their first names. Based on these results, it would seem that this Israeli sample preferred to retain the traditional provider-patient environment.

Adolescent↗

Geocoding addresses from a large population-based study: lessons learned.

BACKGROUND: Geographic information systems (GIS) and spatial statistics are useful for exploring the relation between geographic location and health. The ultimate usefulness of GIS depends on both completeness and accuracy of geocoding (the process of assigning study participants' residences latitude/longitude coordinates that closely approximate their true locations, also known as address matching). The goal of this project was to develop an iterative geocoding process that would achieve a high match rate in a large population-based health study. METHODS: Data were from a study conducted in Wisconsin using mailing addresses of participants who were interviewed by telephone from 1988 to 1995. We standardized the addresses according to US Postal Service guidelines, used desktop GIS geocoding software and two versions of the Topologically Integrated Geographic Encoding and Referencing street maps, accessed Internet mapping engines for problematic addresses, and recontacted a small number of study participants' households. We also tabulated the project's cost, time commitment, software requirements, and brief notes for each step and their alternatives. RESULTS: Of the 14,804 participants, 97% were ultimately assigned latitude/longitude coordinates corresponding to their respective residences. The remaining 3% were geocoded to their zip code centroid. CONCLUSION: The multiple methods described in this work provide practical information for investigators who are considering the use of GIS in their population health research.

Data Collection↗

Erectile dysfunctions in patient-physician communication: optimized strategies for addressing sexual issues and the benefit of using a patient questionnaire.

INTRODUCTION: Erectile dysfunctions are prevalent but underdiagnosed and undertreated health problems. Communication barriers between patients and physicians are one of the main reasons for this and responsible for a low report rate of sexual dysfunction. AIM: The main aim of the study was to investigate which phrasing and communication strategies gained the highest acceptance from physicians and their patients and were considered the most effective. MAIN OUTCOME MEASURES: A documentation form on which each consultation was rated by the participating physicians. METHODS: A large group of physicians was asked to hand out a short patient questionnaire to all male patients over 30 years. The physician was instructed to discuss the questionnaire with the patient and to ask him about sexual problems. A total of 1,191 physicians took part in the study that documented a total of 10,622 consultations with an average duration of 15 minutes. RESULTS: The main results were: (i) the patient questionnaire found a high level of acceptance and 54% of discussions of sexual health were prompted by it; (ii) the patients' reaction to physicians addressing sexual health was positive in more than two-thirds of the sample and characterized by openness, willingness to communicate, and relief that their sexual problems had been addressed; (iii) from the physicians' perspective, the most favored communication strategies were a clear signaling of a willingness to talk, and addressing treatment possibilities or signaling that help was available; and (iv) the resulting discussion led to further diagnostic measures in 25% of patients and to further therapeutic measures in 60% of patients. CONCLUSIONS: There are good grounds for concluding that: (i) addressing a patient's sexual health as part of a physician's everyday routine is feasible in terms of duration and content; and (ii) a short patient questionnaire is an excellent aid for patients and physicians for initiating communication on the topic.

Adult↗

Addressing organizational issues into the evaluation of medical systems.

New system design and evaluation methodologies are being developed to address social, organizational, political, and other non-technological issues in medical informatics. This paper describes a social interactionist framework for researching these kinds of organizational issues, based on research within medical informatics and other disciplines over the past 20 years. It discusses how effective evaluation strategies may be undertaken to address organizational issues concerning computer information systems in medicine and health care. The paper begins with a theoretical framework for evaluation. It then describes the 4Cs of evaluation: communication, care, control, and context. Five methodological guidelines are given for conducting comprehensive evaluations that address these 4Cs. An example of an evaluation research design that fits the guidelines and was used in an evaluation of an on-line clinical imaging system is discussed. Results of the evaluation study illustrate how this approach addresses organizational concerns and the 4Cs.

Communication↗

Preparation of name and address data for record linkage using hidden Markov models.

BACKGROUND: Record linkage refers to the process of joining records that relate to the same entity or event in one or more data collections. In the absence of a shared, unique key, record linkage involves the comparison of ensembles of partially-identifying, non-unique data items between pairs of records. Data items with variable formats, such as names and addresses, need to be transformed and normalised in order to validly carry out these comparisons. Traditionally, deterministic rule-based data processing systems have been used to carry out this pre-processing, which is commonly referred to as "standardisation". This paper describes an alternative approach to standardisation, using a combination of lexicon-based tokenisation and probabilistic hidden Markov models (HMMs). METHODS: HMMs were trained to standardise typical Australian name and address data drawn from a range of health data collections. The accuracy of the results was compared to that produced by rule-based systems. RESULTS: Training of HMMs was found to be quick and did not require any specialised skills. For addresses, HMMs produced equal or better standardisation accuracy than a widely-used rule-based system. However, accuracy was worse when used with simpler name data. Possible reasons for this poorer performance are discussed. CONCLUSION: Lexicon-based tokenisation and HMMs provide a viable and effort-effective alternative to rule-based systems for pre-processing more complex variably formatted data such as addresses. Further work is required to improve the performance of this approach with simpler data such as names. Software which implements the methods described in this paper is freely available under an open source license for other researchers to use and improve.

Data Collection↗