[Cytology of urinary sediments in the diagnosis of renal, extrarenal and bladder diseases].
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A population of workers exposed to bladder carcinogens has been studied by comparing their immunoreactivity against bladder cancer cells and against a control cancer cell with that found in normal individuals and in patients with bladder cancer. Data are presented which indicate equivalent increases in specific reactivity against bladder cancer cells in clinically normal carcinogen-exposed workers and in patients with bladder cancer. Increases in reactivity are related to degree of exposure and also to early malignant changes in the urothelium. This indicates that immune recognition of tumour antigens does occur before development of overt malignancy.
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The laboratory diagnostic spectre in diseases of the kidneys and the urinary bladder is demonstrated in form of a 3-step-programme. The concentration of suitable investigation methods in complexes allows a rational and economical diagnostics for patient and physician. A standardisation of the diagnostics in out-patient department and clinic essentially contributes to the reduction of excessive work in overcharged laboratories as well as to the shortening of the patient's stay in the hospital.
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