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At least 73 records · Page 4Linked to original sources
PubMed1980

Increasing hand efficiency at cold temperatures by training hand vasodilation with a classical conditioning-biofeedback overlap design.

The prolonged exposure of hands to cold environments leads to substantial cold pain and severe deterioration of manual dexterity, finger dexterity, hand strength, and tactile sensitivity. This study taught volunteers to warm their hands at -14 degrees Celsius and measured the hand efficiency effects. The subjects were six male and female nonsmoking volunteers. All research was conducted in a cold chamber during the warm summer months to eliminate seasonal factors. A combined multiple-baseline/ABA single-subject design with multiple replications was used. Each subject's hand performance was obtained for both hands in warm and in cold conditions. One hand was trained and both hands were retested in the cold. The second hand was trained and both hands were retested in the cold. Finally, the subject inhibited warming while in the cold (treatment removal) and both hands were tested again. The treatment itself used biofeedback instrumentation to extend and enlarge previously classically conditioned vasodilative episodes. The procedure was found to be effective for bringing about temperature changes in the cold. Large treatment effects were found on all hand efficiency measures. The results suggest wide implications for the workplace, for theory, and for future research.

Acclimatization↗
PubMed2006

The daily incidence of acute heart failure is correlated with low minimal night temperature: cold immersion pulmonary edema revisited?

BACKGROUND: Previous studies suggested a higher incidence of acute heart failure (AHF) during cold months in regions with cold climate. We examined the daily incidence of AHF by same-day trough temperature and humidity in a warmer region. METHODS AND RESULTS: All admissions for AHF (340 patients) to a city hospital, providing the sole emergency medical care to a geographical region of approximately 500,000 people were recorded. Patients were followed through admission and for 6 months after discharge. Low minimal trough temperature was associated with an increase in the same-day AHF incidence. Lowest tercile trough night temperatures were associated with higher AHF incidence (3.5 +/- 2.1 versus 2.4 +/- 1.6, events/24 hours, P = .012). This association was mainly from increased AHF events in nights with the predetermined trough temperature of <7 degrees C (4 +/- 2.1 versus 2.5 +/- 1.7, events/24 hours, P = .0013). This association persisted even after excluding the coldest consecutive 30 days from the analysis. Humidity was not associated with increased AHF event rate. In a post-hoc analysis we have observed doubling of 6-month mortality in patients admitted with AHF during days with lower trough night temperature, despite no apparent worse baseline characteristics or disease severity at admission. CONCLUSIONS: AHF rate is increased during days with lower trough night temperature. If confirmed, these results may have implications on issues related to climate control in houses of the elderly or patients susceptible to heart failure.

Acute Disease↗
PubMed1984

Differences in temperature dependence of muscle contractile properties and myofibrillar ATPase activity in a cold-temperature fish.

Single muscle fibres were isolated from the fast myotomal muscle of the teleost Myoxocephalus scorpius L. and chemically skinned with 1% Brij. Maximum Ca2+-activated force (P0) increased from 14.5 +/- 1.1 N cm-2 at 2 degrees C to 19.1 +/- 1.8 N cm-2 at 15 degrees C (mean +/- S.E.). Maximum contraction velocity was determined by Hill's slack-test method (V0) and by extrapolation from force-velocity (P-V) relationships (Vmax). There was a linear relation between log10 V0 and temperature below 15 degrees C (Q10 = 1.9, P less than 0.01). The force-velocity characteristics of the fibres were determined at 2 degrees C and 20 degrees C. Points below 0.6 P0 on the P-V curve could be fitted by a linear form of Hill's equation. Extrapolated Vmax values were 0.55 muscle lengths s-1 (L0 s-1) at 2 degrees C and 1.54 L0 s-1 at 20 degrees C. Curvature of the P-V relationship was independent of temperature. The Mg2+, Ca2+-ATPase activity of Triton-X 100 extracted myofibrils was determined under similar ionic conditions to those used in skinned fibre experiments. (Ionic strength 0.16 mmol l-1, pMgATP 2.5). A linear relationship between log10 ATPase and temperature was only obtained below 15 degrees C (P less than 0.001). Above 15 degrees C, the Q10 for ATPase decreased significantly. The Q10(0-15 degrees C) for ATPase activity (3.9) was significantly higher than for unloaded contraction velocity. Supercontraction of isolated myofibrils to very short sarcomere lengths and differences in the mechanical constraints for crossbridge cycling between the preparations probably account for the lack of proportionality between these two parameters.

Adenosine Triphosphatases↗
PubMed2005

Growth and survival of Escherichia coli O157:H7 in fresh tropical fruit juices at ambient and cold temperatures.

The survival of Escherichia coli O157:H7 in acidic foods and its enhanced survival in refrigerated acid foods are well documented. This prompted the present study to evaluate the growth potential of E. coli O157:H7 in fresh tropical fruit juices. The pH of the various juices ranged between 3.57 (pineapple) and 6.2 (avocado). Samples were separately inoculated with a mixture of four E. coli O157:H7 strains at initial levels of approximately 10(3) cfu/ml, and stored at refrigeration (4 degrees C) and ambient (20-25 degrees C) temperatures for 120 h. In pineapple juice, some decline in count was noted during ambient temperature storage but complete inhibition was not observed. At refrigeration temperature, the test strains survived without a noticeable decline in number. The pH remained unchanged throughout the experiment at both incubation temperatures. In papaya and avocado juices, counts of the test strains increased at varying rates at both storage temperatures. A decrease in pH was also noted in the stored juice. This study demonstrated that E. coli O157:H7 can survive well in acidic pineapple juice at both incubation temperatures and could also grow luxuriously in fruit juices with relatively higher pH values (>5.7) when stored at ambient and refrigeration temperatures.

Ananas↗
PubMed2005

An evaluation of disinfectants for the sanitation of porcine reproductive and respiratory syndrome virus-contaminated transport vehicles at cold temperatures.

The objective of this study was to evaluate the efficacy of commercially available disinfectants to sanitize porcine reproductive and respiratory syndrome virus (PRRSV) contaminated trailer models in cold climates (-20 degrees C and 4 degrees C). Disinfectants evaluated included Synergize, Aseptol 2000, Biophene, Sentramax, Virkon, Tek Trol, and DC&R. All products were applied to trailers via fumigation at 4 degrees C. Following experimental contamination of model trailers with PRRSV MN 30-100 (5 x 10(5) TCID50), models were tested for the presence or absence of PRRSV-RNA by polymerase chain reaction (PCR) on swabs collected 0, 30, and 60 min after treatment. Treatments included washing only, washing plus disinfectant fumigation, washing plus fumigation, and washing plus overnight drying. The PRRSV-RNA detected across trailers ranged from 0/12 replicates in trailers treated with Synergize or allowed to dry for 8 h. These trailers were also negative for the presence of infectious PRRSV, based on the lack of sentinel pig infection (0/4 replicates). In contrast, the detection of PRRSV-positive swabs by PCR ranged from 3/12 (Aseptol) to 10/12 (Biophene). Based on these results, the efficacy of Synergize was evaluated at -20 degrees C. In an attempt to reduce the impact of freezing on disinfectant activity, 30 mL of disinfectant was added to a 3840 mL of a 40% methanol solution, a 10% propylene glycol (PG) solution, or water alone. The PRRSV-contaminated trailers were treated with 1 of 3 disinfectant mixtures via fumigation, stored for 8 h at -20 degrees C, allowed to thaw, and sampled as described. Trailers treated with 40% methanol or 10% PG did not freeze and were negative for PRRSV-RNA and infectious virus following thawing. In contrast, trailers treated with disinfectant and water were frozen within 60 min at -20 degrees C, and decontamination was not successful.

Animals↗
PubMed2003

ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures.

Mammals detect temperature with specialized neurons in the peripheral nervous system. Four TRPV-class channels have been implicated in sensing heat, and one TRPM-class channel in sensing cold. The combined range of temperatures that activate these channels covers a majority of the relevant physiological spectrum sensed by most mammals, with a significant gap in the noxious cold range. Here, we describe the characterization of ANKTM1, a cold-activated channel with a lower activation temperature compared to the cold and menthol receptor, TRPM8. ANKTM1 is a distant family member of TRP channels with very little amino acid similarity to TRPM8. It is found in a subset of nociceptive sensory neurons where it is coexpressed with TRPV1/VR1 (the capsaicin/heat receptor) but not TRPM8. Consistent with the expression of ANKTM1, we identify noxious cold-sensitive sensory neurons that also respond to capsaicin but not to menthol.

Amino Acid Sequence↗
PubMed1976

The effect of cold temperature mixing on the properties of zinc phosphate cement.

A series of proprietary zinc phosphate cements were evaluated after mixing on glass slabs at three different temperatures, 23 degrees, 6 degrees and -10 degrees C. Working time, setting time, diametral tensile strength, compressive strength and solubility were investigated. From the results of the tests the following conclusions were made: 1) As the temperature of the mixing slab was decreased, the amount of powder required to maintain a constatnt viscosity increased. 2) Compressive, tensile, and solubility values remained constant as the temperature of the mixing slab was decreased provided a consistent viscosity was maintained. 3) Mixing zinc phosphate cement substantially below the dew point is an acceptable practice provided the powder/liquid ratio is modified accordingly. 4) Although the setting time of zinc phosphate cement generally remained constant at temperatures below 6 degrees C, the working time continued to increase at -10 degrees C. 5) Mixing zinc phosphate cemment on a cold mixing slab increases the working time on the glass slab and decreases the setting time in an oral environment. Both of these alterations are clinically beneficial to the orthodontist.

Cold Temperature↗