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Spontaneous resolution of colonic strictures caused by necrotizing enterocolitis: therapeutic implications.

Colonic strictures are now a well recognized complication in infants surviving necrotizing enterocolitis. We describe the clinical course of seven infants with colonic strictures after necrotizing enterocolitis. Only two demonstrated the finding of fixed fibrotic stricture described in the literature, while the remaining five showed atypical radiographic and pathologic features. Two of the five showed partial or spontaneous resolution of post-necrotizing enterocolitis colonic stenoses on follow-up barium enema studies. In three of four patients with colonic resections, the histopathologic examination revealed a surprising absence of irreversible fibrosis or cicatrix formation. Current surgical practice dictates elective resection of these narrowed colonic segments. The radiologic and pathologic findings in our series of patients suggest surgical resection may be unnecessary in selected cases.

Colon

Transrectal ultrasonography in disorders of the seminal vesicles and ejaculatory ducts.

Ultrasonography is an inexpensive, noninvasive, and reliable means of evaluating the integrity of the distal seminal tract. A variety of rare congenital anomalies can be demonstrated by ultrasound applied either transabdominally or by the transrectal route. Ultrasonography provides a unique insight into the function and pathology of ejaculation that may affect fertility and may well produce new diagnostic criteria to explain some of the more unusual symptoms encountered by urologists in general practice.

Constriction, Pathologic

[Repeated operations on the extrahepatic bile ducts].

Experience in repeated operations on the biliary tract in 51 patients is analysed. Endoscopic retrograde cholangiopancreatography is one of the informative methods. The choice of the method of operative treatment must be individualized according to the nature of the pathological process in the biliary system. An endoscopic intervention may be an alternative to surgical operations in many cases.

Adult

Endomyocardial fibrosis with calcification of the myocardium.

A case of endomyocardial fibrosis with intramyocardial calcification was characterized by symptoms of restrictive cardiomyopathy resembling constrictive pericarditis. Pathological findings were typical of those found in classical Davies' disease, originally encountered and described in Uganda.

Calcinosis

Deep venous thrombosis after shoulder arthroscopy.

Deep venous thrombosis after shoulder arthroscopy is so unusual that its occurrence should arouse the suspicion of (a) a hypercoagulable state, or (b) a pathologic extrinsic mass causing venous occlusion. This case of deep venous thrombosis after shoulder arthroscopy led to the discovery of previously asymptomatic Hodgkin's lymphoma that was compressing the innominate vein.

Adult

[Doppler and duplex sonography of the vertebral arteries].

In a prospective study 451 patients were examined with extracranial CW-Doppler sonography (mastoidal slope), suboccipital transcranial Doppler sonography and colour-coded duplex sonography to evaluate unusual vertebral arteries (hypoplasia, stenosis and occlusion). Colour duplex sonography was used as reference method. CW-Doppler sonography had a sensitivity of 100% and a specificity of 27% for the detection of an unusual vertebral artery. For transcranial Doppler sonography these values are 38% and 58%. Our study showed that CW-Doppler is a useful screening examination for identifying pathological findings of vertebral arteries. In case of abnormalities in CW-Doppler, duplex sonography, especially colour-coded duplex sonography, should be added.

Adult

[Hydrodynamic and radiologic examination of the common bile duct].

The operative study of the common bile duct was carried out with the hydrodynamics methods (flow and resting pressure) in 433 patients and with the operative cholangiography in 383 patients. The hydrodynamics explorations pointed-out a margin of mistake due to falses positives and negatives of the 2.7% and the operative cholangiographies of the 8.6%. The association of both methods, hydrodynamics and radiologycs, allowed us to estimate that the diagnostic mistake is reduced to 0%. It is established in this work the necessity of carring out the flow, the measure of the resting pressure and the cholangiographies; in all the patients that are operated on the biliary tract because the diagnostic accuracy is the 100%. It is discussed the value of the diameter of the common bile duct for affirming the eventual existence of obstruction of the lower part of the common bile duct and the values are correlated, measured in mm., with pathological founds. It is considered the value of the hydrodynamics methods in the diagnostic of the stenosis of the sphincter of Oddi.

Adolescent

[Post-stenotic aneurysm following incarceration of the popliteal artery. Description of a case].

The paper reports a case of post-stenotic aneurysm following an Inshua type II incarceration of the popliteal artery which was treated surgically, and associated with concomitant popliteal venous thrombosis, with complete remission of all clinical symptoms. The paper underlines the rarity of this pathology and the even rarer association with homolateral thrombosis of the popliteal vein. Anomalies which may occur following the incarceration of the popliteal artery are discussed, as are the causes for dilatory degeneration.

Aged

[Results of endoscopic treatment of choledochal calculosis and cicatricial stenosis of the papilla].

The results obtained with endoscopic papillo-sphincterotomy in the treatment of gallstones and cicatricial stenosis of the papilla are reported. The treatment proved effective in 91.3% of patients with papillary stenosis and the incidence of side-effects (cholangitis, pancreatitis, bleeding, perforation) was 7.5%. Endoscopic PST hitherto restricted to cases judge inoperable due to serious concomitant pathologies may be a valid alternative to surgery wherever total sphincter dysfunction can be ascertained.

Aged

Aqueductal stenosis as isolated localization involving the central nervous system in children affected by von Recklinghausen disease.

The Authors report three cases of non tumoral aqueductal stenosis associated with von Recklinghausen disease in children. Moreover, 16 similar cases collected from the literature are illustrated. The clinical features are evaluated in light of literature's data. Among all 19 cases, the median age was 19 years (range 6-46 years) and 9 patients were under the age of 13 years. In this latter group, the most represented clinical symptoms were headache and gait disturbances. As regards the neuroradiological procedures, CT scan represented the best tool in the evaluation of the ventricular size. Our own three cases underwent to ventriculo-atrial shunt procedures, followed by clinical recovery (follow-up: 3 months-5 years). In conclusion it is felt that, among all the pathological events usually described in patients affected by neurofibromatosis, aqueductal stenosis seems to belong to the natural history of this disease.

Brain Diseases

Delayed filling of retinal and ciliary circulation after central retinal artery occlusion.

The filling times of the retinal and choroidal circulation were evaluated in 17 patients with central retinal artery occlusion by means of fluorescein angiography. A correlation between the filling times of the two circulations was found. However, two filling patterns were seen: first, both fillings delayed; second, both fillings normal. It is probable that in the former case an obstructive disease of the carotid arteries exists, while in the latter case an important pathology of the carotid arteries is lacking, favouring a rapid restoration of the retinal circulation. This hypothesis seems to be confirmed by the results of the Doppler velocimetry of the carotid arteries.

Aged

Nontumoral aqueductal stenosis in children affected by von Recklinghausen's disease.

The authors report three cases of primary nontumoral aqueductal stenosis associated with von Recklinghausen's disease in children. Moreover, 16 similar cases collected from the literature are presented. The clinical features are evaluated in light of data from the literature. Among all 19 cases, the median age was 19 years (range 6-46 years), and nine patients were under the age of 13 years. Our own patients underwent ventriculoatrial shunt procedures, followed by clinical recovery (follow-up 2-5 years). In one patient, computed tomography scanning performed 20 months after the operation showed a chronic calcified subdural hematoma in the right frontoparietal area. In conclusion, it is felt that, among all the pathological events usually described in patients affected by neurofibromatosis, primary aqueductal stenosis seems to be part of the natural history of this neurological syndrome.

Cerebral Aqueduct

Intermittent axillary vein obstruction in a competitive canoeist.

The case is reported of a competitive canoeist with intermittent axillary vein obstruction secondary to shoulder girdle muscle hypertrophy. The anatomy of the axilla, pathology of the axillary vein, and reported cases of sports injuries involving the axillary vein are discussed. This would appear to be the first report of such an occurrence in a canoeist.

Adult

[Stenosis of the celiac tripod due to extrinsic compression. A case report].

The Authors, starting from the observation of a case of stenosis of the celiac tripod, caused by compression "ab estrinseco", examine the physiopathological, clinical, aetiopathogenetic and therapeutical aspects of the pathology in question. In accordance with medical literature interpretative nosological doubts are also raised which, not with standing the improved research techniques, make it extremely difficult to suggest an accurate surgical procedure.

Abdominal Pain

Is ERCP manometry useful in the choice of treatment of stones of the common bile duct?

To verify the appropriateness of sphincterotomy as the treatment of choice of choledocholithiasis, since 1980 we have been using endoscopic retrograde cholangiopancreatographic (ERCP) manometry of the sphincter of Oddi (SO). This method allows direct investigation of SO motor activity and provides useful information regarding the presence of benign papillary stenosis (BPS). Thirty-four patients were investigated because the radiological examination indicated BPS might be present. Of these, 20 had common bile duct (CBD) stones, while the remaining 14 presented with biliarylike pain and one or more of the following: CBD dilation (larger than 12 mm); emptying of the ERCP contrast medium took longer than 45 min; abnormal liver function tests. Moreover, 8 healthy volunteers served as controls. Our results show that the incidence of SO motor anomalies is very low in the presence of choledocholithiasis, while it is substantial in patients with suspected SO dysfunction. These observations would suggest that, unlike the traditional view, BPS is rarely secondary to biliary lithiasis. Therefore, most of the sphincterotomies performed that are based on the assumption of underlying SO pathology should be considered unnecessary. Under these circumstances, the physiological role of a functioning SO has induced us to advocate sphincterotomy, surgical or endoscopic, in selected cases only.

Adult

Late death after arterial switch operation for transposition of the great arteries.

Fifty-nine patients survived for more than 1 month after an arterial switch operation (ASO). Diagnoses in these patients included transposition of the great arteries in 27, transposition of the great arteries with ventricular septal defect in 28, and double-outlet right ventricle in four. There were six late deaths (10%) during the follow-up period, and all of them occurred suddenly and unexpectedly. Four of the six late deaths were in patients who had undergone ASO in the neonatal period. Late deaths occurred from 40 days to 10 months after the operation. Autopsies were performed in all six patients. The cause of these late deaths was acute myocardial infarction. Five patients died of subendocardial infarction resulting from stenosis of the left main coronary artery. On pathologic examination, a fibrocellular intimal thickening was noted at the proximal region of the right and left coronary arteries, which resulted in 80% stenosis on average.

Abnormalities, Multiple

Intrahepatic bile duct strictures after human orthotopic liver transplantation. Recurrence of primary sclerosing cholangitis or unusual presentation of allograft rejection?

One of 55 patients transplanted for sclerosing cholangitis during the cyclosporin-steroid era (March 1980-June 1986) developed intrahepatic biliary strictures in the absence of allograft rejection within the 1st year posttransplantation. Although many causes underlie biliary pathology in the postoperative period (i.e., arterial injury, ischemia, chronic rejection, cholangitis), recurrent disease remains a possibility.

Adult