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PubMed1958

SEBORRHOEA.

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Dermatitis↗
PubMed1991

[Lectin histochemistry in psoriasis, lichen planus and keratosis seborrheica].

Using 14 different biotinyl lectins and avidin horseradish peroxidase, we studied the lectin binding patterns in the epidermis of the lesions in 37 cases of psoriasis, 9 cases of lichen planus and 18 cases of keratosis seborrheica. In comparison with normal human skin, epidermal lectin binding patterns in these diseases showed considerable qualitative and quantitative abnormalities, among which some were characteristic. These findings revealed significant changes in keratinocytic glycoconjugates in these diseases, providing clues to their pathogeneses. The detected changes suggest that the maturation pathway of the keratinocytes in psoriasis differs qualitatively from the normal cases and is not merely a result of rapid transit of the cells.

Dermatitis, Seborrheic↗
PubMed1980

[Focal acantholytic dyskeratosis in verruca seborrheica].

One case of seborrhoeic keratosis with extensive acantholysis and moderate dyskeratosis is reported. The histological features ressembled those of Darier and Hailey-Hailey diseases. Another seborrhoeic wart simultaneously removed had no microscopic abnormalities. The dermatoses in which focal acantholytic dyskeratosis has been observed are reviewed and similarities and possible relationships to epidermolytic hyperkeratosis are discussed. The relative lack of specificity of these changes is emphasised as well as the occasional coexistence of both types and the variability of histological patterns observed on Grover's transient acantholytic dermatosis. These facts suggest a close relationship between the above mentioned histopathological patterns concerning the mechanisms of its production.

Acantholysis↗