Icelanders opt out of genetic database.
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Structural genomics projects aim to provide an experimental or computational three-dimensional model structure for all of the tractable macromolecules that are encoded by complete genomes. To this end, pilot centres worldwide are now exploring the feasibility of large-scale structure determination. Their experimental structures and computational models are expected to yield insight into the molecular function and mechanism of thousands of proteins. The pervasiveness of this information is likely to change the use of structure in molecular biology and biochemistry.
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Unexpectedly rapid progress towards the sequencing and listing of the genes in the human genome has caused a flurry of excitement (and injured pride) in the genome community which is likely to surface in Washington next week.
Opposition to the patenting of genomic inventions threatens to erode the foundation of intellectual property rights needed to convert innovative research into new drugs, vaccines and diagnostic tests.
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Principles of access to public and private databases are often contentious, and a proposal in this issue will no doubt spark more debate. Meanwhile, Nature is taking a small step towards a database for taxonomists.
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