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Results for “GANGLIA, SPINAL”

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At least 73 records · Page 4Linked to original sources
PubMed2001

Lumbar spinal ganglia enhancement after gadolinium chelate administration: a radio-histological correlation.

The aim of the present study was to assess the frequency of enhancement of lumbar spinal ganglia after Gadolinium chelate injection in patients without radiculopathy, and to correlate the enhancement with histology. This study is based on the analysis of MR lumbar examinations conducted on 18 patients without radicular symptoms, or previous surgery of the lumbar spine, or disease of the nervous system. The patients were imaged with a 1.5 T unit. Sagittal images were first obtained with a T1-weighted turbo spin-echo. Axial and sagittal images were then obtained with a T1-weighted turbo spin-echo, fat-saturated sequence after Gadolinium intravenous injection from the T12/L1 to the L5/S1 level. All 180 spinal ganglia demonstrated an important and homogeneous enhancement after Gadolinium injection. Four spinal ganglia obtained by dissection from four different fresh cadavers were studied by light microscopy to determine the potential relationship between contrast enhancement and presence and topography of vessels within the spinal ganglia. Vessels were particularly abundant at the peripheral zone of the spinal ganglia. The post-contrast enhancement of the spinal ganglia after Gadolinium administration has to be known and may be explained by the microvasculature pattern.

Adult↗
PubMed1985

Spinal ganglia and peripheral nerves from a patent with Tay-Sachs disease. Morphological and ganglioside studies.

We examined the spinal ganglia and peripheral nerves from a patient with Tay-Sachs disease, comparing the other nervous tissues morphologically and lipid-biochemically. The spinal ganglia and peripheral nerves showed numerous membranous cytoplasmic inclusion bodies (MCBs), which are characteristic of GM2-ganglioside storage in the neuronal cell bodies of the patient brains. In spinal ganglia, all neurons and satellite cells around the neurons contained membrane-bound lipid materials. In peripheral nerves, Schwann cells and myelinated axons except for enlarged axons were devoid of MCBs. Major ganglioside stored in both spinal ganglia and peripheral nerve was also GM2-ganglioside. The contents of ganglioside in the spinal ganglia and peripheral nerves were 50 and 10 times more than those from normal tissues, respectively. The spinal cord contained a slightly higher amount of gangliosides than the normal control. The cerebral white matter totally demyelinated in this patient accumulated a much higher amount of gangliosides than the cerebral gray matter. The retinal tissue showed GM2-ganglioside as the major one also.

Cerebral Cortex↗
PubMedDate not supplied

Pseudo-intracellular collagen tangles in human spinal ganglia.

A new structure was found in the spinal ganglia of 6 out of 215 human autopsy cases with various disorders. It was composed of ballooned cells fully packed with fibrillar structures showing the same staining properties as collagen. Ultrastructurally the fibrillar structures were bundles of collagen fibres with a striation of about 70nm periodicity, and they were enclosed by the cell membrane invaginated in a very complex manner into the cytoplasm. This structure, which we named 'pseudo-intracellular collagen tangle', was considered to result from a disturbance in the releasing process of collagen fibre from fibroblasts. The aetiology of the structure is unknown, but it might represent one of regressive or senile changes in human spinal ganglia.

Aged↗
PubMed1975

Quantitative relationships between nerve and satellite cells in spinal ganglia: an electron microscopical study. II. Reptiles.

In the spinal ganglia of two species of reptiles (gecko and lizard) the volume of the perikaryal satellite cell sheath was found directly proportional both to the volume and surface area of the related neuronal body. This result agrees with that obtained in a previous research on two species of mammals (cat and rabbit). A quantitative balance between neuronal bodies and their associated glial tissue therefore exists also in the spinal ganglia of zoological species phylogenetically quite distant from mammals. The quantitative relationship between glial and nerve tissue was found to be lower in the gecko and lizard than in the cat and rabbit. This difference could have a phylogenetic significance, and/or it could be explained by the lower metabolic rate in the nervous system of the poikilotherms in respect to mammals.

Animals↗
PubMed1975

Uptake of tritium labelled chloroquine into organized cultures of rat spinal ganglia. An electron microscope autoradiographic study.

Cultured spinal ganglia of the rat treated with 3-3H-chloroquine led to the formation of numerous multilamellated bodies (MLB) in the perikarya of neurons, satellite cells, and fibroblasts. Electron microscope autoradiography showed label over and near a considerable proportion of MLB. The action of chloroquine in MLB is discussed with regard to its effect upon lysosomes.

Animals↗
PubMed1976

Cytochemical investigations of proteins and RNA in spinal motoneurons and neurons of spinal ganglia of the rat after space flight.

The content of RNA and cytoplasmic protein was assayed by methods of quantitative cytochemistry in motoneurons of anterior horns of the spinal cord and neurons of spinal ganglia of rats flown for 22 d. It was shown that the 22-d space flight did not change the RNA content in motoneurons of anterior horns of the spinal cord and reduced the RNA content in large neurons of spinal ganglia. The protein content in the cytoplasm of motoneurons and neurons of spinal ganglia was significantly lowered as compared with the control. The RNA content 27 d postflight in motoneurons of anterior horns of the spinal cord was significantly reduced and in neurons of spinal ganglia it did not differ from the control. On the 27th postflight day the protein content in the cytoplasm of motoneurons returned to the preflight level and in the cytoplasm of large neurons of spinal ganglia remained lowered.

Animals↗
PubMed1984

[Morphometric observations on the number of neurons in spinal ganglia].

Nerve cell number has been determined in the thoracic spinal ganglia XVII to XXII of chick embryos of 14-18 days of incubation. It is shown that these ganglia constitute a statistically homogeneous population in respect of the number of their constituent nerve cells. The statistical frequency distribution of the thoracic spinal ganglia according to the number of their neurons is unimodal, but markedly asymmetrical with a distinct positive skewness; the distribution differs significantly (P less than 0.05) from a normal (Gaussian) distribution.

Animals↗
PubMed1978

Quantitative histomorphological studies on the spinal ganglia of the Indian buffalo (Bubalus bubalis).

Spinal ganglia of C3, C7, T5, T12, L2 and L5 spinal dorsal roots were studied. These ganglia vary in their size. Their greatest cross-sectional area was at C7 (2.12 cm2) in the cervical region and at L5 (1.39 cm2) in the lumbar region. The neurons were either spherical or oval in contour. The smallest neurons (mean size 68.50 X 55.64 micrometer) were located in the T5 ganglion, while some of the largest neurons (mean size 79.17 X 63.34 micrometer) were noticed in the C3 ganglion. As for their cross-sectional area, the ganglionic neurons at the L5 level were the largest (3,713.16 micrometer2), while the least value (2,994.60 micrometer2) was noted in T5 ganglionic cells. The amphicytes (satellite cells) were clearly defined. The neuronal cytoplasm revealed finely granular Nissl material. The neurons exhibit a pale-staining, centrally located vesicular nucleus with a prominent nucleolus. Few multipolar cells with eccentric nuclei were noted in the L5 ganglion.

Animals↗
PubMed1989

Postischaemic changes in the satellite cells of dog spinal ganglia.

Changes in the satellite cells of the spinal ganglia were studied in dogs after ischaemia induced by repeated 40 min ligation of the abdominal aorta, followed by 1-6 days' survival. The nuclei of the satellite cells were hypertrophic, with a tendency to lobulation, and contained conspicuous nucleoli. The mitochondria were enlarged and denser, but their internal structure remained intact. The Golgi complex displayed signs of hyperplasia and an increase in the vesicular component. An increase in the number of filaments and free ribosomes could be seen in the cytoplasm of the satellite cells. There was also a remarkable increase in the endoplasmic reticulum, especially after six days' survival. The qualitative and quantitative changes testify to stimulation of the metabolic activity of the satellite cells in the postischaemic period.

Animals↗
PubMed1989

[Influence of electroacupuncture on ACh content and AChE activity in the spinal ganglia of rat].

The spinal ganglion a cell body storage of somatic primary-sensory neurons, is considered as an important region for neurochemical research of primary afferent nerves. The present experiment aims at the observation on the Ach content and its changes in the ganglia of 128 rats by means of biochemical methods under the effect of administration of Neostigmini and application of electroacupuncture. It is found that there are evidence of existence of Ach in the ganglia and when the AchE activity in the periphery nerve system is inhibited, the Ach content of ganglia rose. In addition, during acupuncture (applied at acupoint "Huantiao") analgesia, no apparent changes of Ach content can be visualized in spinal ganglia, however, the level of AchE activity goes up evidently. The foregoing results indicate that in the somatic primary-sensory neuron Ach is one of important neurotransmitters which may influence and take part in the transmission of sensory information through primary afferent nerves.

Acetylcholine↗