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PubMed1992

Glossodynia--psychodynamic basis and results of psychopathometric investigations.

Between 1985 and 1988, 131 patients suffering from glossodynia were submitted to a careful examination that included a neurological work-up, a detailed psychiatric interview and a number of psychological tests. Particular attention was paid to psychosomatic and psychopathologic disorders. The average age of the patients was 55 yr, and 73% of them were female. In 40% of patients, the psychiatric interview revealed no psychopathological findings, while in most of them, a psychiatrically relevant disorder, usually depression, was found. All patients had an unremarkable neurological status, and the EEG's showed no pathological changes. Psychodynamic considerations in conjunction with the elevated scores for depressive mood, anxiety and tension suggest that glossodynia is an expression of a psychosomatic disorder.

Adult↗
PubMed1977

Glossopyrosis due to adenoid cystic carcinoma.

Glossopyrosis and glossodynia may occur from local or systemic factors or from any irritation along the course of the lingual nerve. Although cylindroma is relatively rare, it must be considered along with other malignant lesions when neurologic symptoms of burning and pain of the tongue persist. Examination of the lesion is best carried out as multiple needle biopsies rather than as open biopsy, in order to avoid seeding of the skin and lymphatics of the neck. Recurrences are frequent and, because of the slow growth, there must be a long follow-up period. Metastases to the lung and brain, although late, occur in large numbers of patients. Best results are obtained by a combination of radiation therapy and operation because the infiltration is so extensive that operation alone may not eliminate the tumor completely.

Carcinoma, Adenoid Cystic↗
PubMed1988

Glossodynia, iron deficiency anemia, and gastrointestinal malignancy. Report of a case.

A postmenopausal woman was referred by a medical specialist for the evaluation of xerostomia and glossodynia. An ensuing oral diagnostic workup showed that the patient was suffering from iron deficiency anemia secondary to blood loss caused by a tumor in the large intestine. The original oral symptoms resolved after a right hemicolectomy.

Adenocarcinoma, Mucinous↗
PubMed2004

Treatment of glossodynia with olanzapine.

A 73-year-old white male with a 6-month history of glossodynia, unresponsive to clotrimazole troches, cevimeline, triamcinolone dental paste, paroxetine, and lorazepam presented to the dermatology clinic for consultation. Work-up revealed no oral abnormalities and no underlying systemic disorder. He denied symptoms consistent with a psychiatric disorder. A detailed free amnestic assessment by a board certified Geriatric Psychiatrist (John S. Kennedy, MD) found that the patient was oppressed by the pain. He did not meet the criteria for major depression nor did he have any anxiety disorder or delusions. Because of the presence of dysphoria and anticipatory anxiety secondary to glossodynia, the patient was started on olanzapine. Improvement of pain symptoms were noted within 3 days with full resolution of symptoms at 1- and 3-month follow-ups. Dysphoria and anticipatory anxiety remitted fully upon pain relief.

Aged↗
PubMed2004

Initial diagnosis of anemia from sore mouth and improved classification of anemias by MCV and RDW in 30 patients.

Thirty patients with a wide range of sore mouth that led to the diagnosis of iron deficiency in 12 patients, pernicious anemia in 8 patients, combined deficiency of iron and vitamin B12 in 2 patients, and anemia of chronic disease in 8 patients were investigated. The oral signs and symptoms included glossitis, glossodynia, angular cheilitis, recurrent oral ulcer, oral candidosis, diffuse erythematous mucositis, and pale oral mucosa. The values of hemoglobin in 30 patients varied from normal to severe life-threatening levels, but none had developed generalized symptoms sufficiently advanced to arouse suspicions of anemia before they visited the Oral Medicine Clinic. The aim of this paper is to describe a retrospective study of 30 patients with oral changes as the initial manifestation of nutritional deficiency or anemia of chronic diseases. Improved diagnosis and classification of anemia based on the mean and heterogeneity of red cell size will be discussed.

Adult↗
PubMed1999

Medically unexplained chronic orofacial pain. Temporomandibular pain and dysfunction syndrome, orofacial phantom pain, burning mouth syndrome, and trigeminal neuralgia.

Orofacial pain syndromes pose a dilemma for physicians. Even when the patient is referred, quality medical care requires that the physician be acquainted with current evidence-based practice. Such practice may be radically different from the traditional view. This article reviews the differential diagnosis and treatment of the most common medically unexplained orofacial syndromes.

Chronic Disease↗
PubMedDate not supplied

A psychiatric appraisal of "glossodynia".

"Glossodynia" is a diagnostic rubric that includes patients enduring pain or a burning sensation in the tongue without any oral pathology or systemic disease. Psychiatric profiles of 50 women patients with "glossodynia" were compared with those of control subjects. The patients scored significantly lower on the Extraversion Scale of the Eysenck Personality Questionnaire and higher on the Toronto Alexithymia Scale than the control subjects, whereas there was no significant difference in the mean General Health Questionnaire score. The psychopathology of "glossodynia" may be more markedly associated with personality trait characteristics than with neurotic or depressive symptoms.

Adult↗
PubMed1976

Relation between idiopathic glossodynia and salivary flow rate and content.

From a series of 50 patients complaining of sore tongue, 13 were found to be suffering from idiopathic glossodynia. All were women in the postmenopausal stage. The salivary flow rate, protein, phosphate, and electrolyte content (Na, K, Ca, Mg) were measured in unstimulated saliva of these patients. Protein, potassium and phosphate concentrations were significantly higher than in the control group. The results indicate that hormonal disbalance might be a factor in the etiology of this type of sore tongue.

Aged↗
PubMed1987

Dilemma in treatment of patients suffering from orofacial dysaesthesia.

A retrospective study of 64 patients with orofacial dysaesthesia is presented. Special emphasis is placed on the patients' symptoms and on the manipulative treatments they received before they were referred for psychiatric consultation. The patients had suffered from chronic orofacial pain or feelings of discomfort for periods ranging from 6 months up to 25 years. The patients had visited several specialists and had received numerous manipulative or medical treatments, the most common of which were repeated medication (drug treatment), TMJ dysfunction treatment, endodontic or exodontic treatment, and surgical explorations. However, the success of all these clinical efforts was very limited because of the apparent psychosomatic origin of the complaints. This study clearly shows that psychiatric consultations are still too seldom made in patients with chronic orofacial dysaesthesia, that many patients have a mental disorder, and that most chronic psychosomatic pain disorders are treated as acute specific pain.

Adult↗
PubMed1998

Methodologic considerations for research in traditional (alternative) medicine.

The widepsread use, in the United States and other western countries, of alternative medical practices often derived from traditional systems of health has intensified the need to evaluate their safety and effectiveness. These practices tend to generate polarized attitudes of either acceptance or rejections. Opponents reject them because, they claim, good scientific research has not supported their use. Proponents insist that current scientific methodologies are not appropriate to evaluate these practices. This article briefly examines these issue, suggesting that the answer lies between these 2 extreme positions. Various methodologic issues are considered, and suggestions are made to adapt scientific methodology, where appropriate, to respect the particularities of alternative medicine.

Clinical Trials as Topic↗
PubMed1998

Effectiveness of kampo medicine (sai-boku-to) in treatment of patients with glossodynia.

OBJECTIVE: The purpose of this study was to evaluate the usefulness of a Kampo medicine (Sai-boku-to) for treatment of patients with glossodynia. STUDY DESIGN: Sai-boku-to or an antianxiety drug (diazepam) with vitamin B complex was administered orally for 3 months to each of 200 patients with glossodynia. Clinical examination evaluated the following subjective symptoms: pain, burning sensation, and discomfort. Effectiveness was evaluated as follows: "markedly effective," all 3 symptoms disappeared; "effective," pain improved; "ineffective," no improvement in pain. RESULTS: The effective rates were 70% after 1 month, 85% after 2 months, and 92% after 3 months of administration of Sai-boku-to (the Kampo group) and 74% after 1 month, 71% after 2 months, and 69% after 3 months of administration of the antianxiety drug with vitamin B complex (the control group). No significant side effect was noted in the Kampo group, but sleepiness was recorded in 33 cases in the control group. CONCLUSIONS: The results indicate that Sai-boku-to may be a clinically useful medicine for the long-term treatment of patients with glossodynia.

Adult↗