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Geographic distribution of calcium pyrophosphate (CPPD) deposition disease in pre-Columbian North America: independent validation of CPPD criteria.

Calcium pyrophosphate deposition disease (CPPD), a form of crystalline arthritis, has a unique distribution in the Early to Middle Archaic Periods (3000 to 8000 years before the present) of North America, contrasting with the generalized geographic distribution of osteoarthritis. Incursion of CPPD into specific regions suggests possible migration patterns. The disparate geographic distribution of CPPD and osteoarthritis provide independent verification of the validity of diagnostic criteria utilized for the identification of CPPD.

Arthritis↗

A study about geographical distribution of root lesion nematode (Pratylenchus loosi, Loof 1960) in tea gardens at Guilan Province, Iran.

Root lesion nematode of tea (Pratylenchus loosi) is one of the most dangerous and distractive pests in all over areas in the world where tea grows. In Iran, this species was one of the quarantine pests that for first time it were separated from the Japan imported tea slips and reported by Maafi (1993). Nowadays it has been distributed in some tea growth areas of Guilan and Mazandaran provinces (North of Iran). In this study, geographical distribution of this pest is reported on some tea growth areas of Guilan province. In order to, 147 samples from root and soil around them were investigated. These samples were gathered from various gardens of Guilan province. They were transferred to nematology lab with suitable temperature and moisture conditions and were stored at 5-10 degrees C until extraction time. Centrifugal methods for nematode extraction from soil (Jenkins, 1964) and from root (Coolen & D'Herde, 1972) were used. The nematode was identified by Handoo & Golden (1989) and Frederick & Tarjan (1989) diagnostic keys. According to this study different infested areas and geographical distribution were detected in Guilan province. Results indicated that many important tea growth areas in Guilan were infested by this nematode. In addition, it seems that it has been distributed during short time.

Animals↗

Geographic distribution of physician manpower: the GMENAC (Graduate Medical Education National Advisory Committee) legacy.

The Graduate Medical Education National Advisory Committee (GMENAC) projected the need for and supply of physicians and other providers, recommended time and access standards for health care services, and developed guidelines for the geographic distribution of physicians. Since this study, analysts have given scant attention to national problems of physician geographic distribution. The issue deserves additional scrutiny in light of the current continuing problems of underservice in rural areas. The emergence of geographic information systems offers a unique opportunity to acquire data on provider distribution and provide a framework for developing and testing redistribution policy.

Catchment Area, Health↗

Similar geographical distribution of multiple sclerosis and cancer of the colon.

A search was made of all diseases listed in the Annual Statistics of the World Health Organization to determine if any disease had the peculiar geographical distribution of multiple sclerosis. Of the approximately 83 diseases listed, only cancer of the colon was similar in geographical distribution and in the slight preponderance of females dying with the disease. The epidemiology of both diseases is reviewed, particularly with regard to their appearance in certain migrant populations.

Adult↗

Geographical distribution of cutaneous melanoma in Queensland.

Queensland has the highest incidence of cutaneous melanoma in the world, and the reported incidence has more than doubled in the last 15 years. The general geographical distribution of melanoma patients correlates negatively with latitude on a world scale. This suggests that exposure to solar ultraviolet rays is aetiologically important. The geographical distribution of melanoma patients in Queensland was examined by reviewing the residential addresses of all incident cases in a 12-month period from July 1, 1979, and no association with latitude was found. Rather there was a significantly increased incidence of melanoma in coastal, compared to inland, regions. When the distribution of doses of erythemal solar ultraviolet radiation in Queensland is examined, taking into account the effects of cloud cover, surface reflectance, and human behaviour, the observed regional differences in incidence may yet be explained by the variation in actual exposure to ultraviolet radiation received by the population.

Australia↗

The geographical distribution of psychiatrists in Canada: unmet needs and remedial strategies.

Many efforts are underway to rationalize the process of manpower planning in psychiatry. A wide variation in the geographic distribution of psychiatrists remains. A multidimensional assessment of the needs of a population is recommended, based on the epidemiology of mental disorders, professional and institutional needs, consumer estimates, and the requirements of subgroups. Counting the number of vacant positions for psychiatrists can be misleading. Professional norms for the optimal access of a population to psychiatric services and standards for the quantity and/or quality of services provided need to be developed. Potential outcome measures are suggested, along with a three-tiered system of estimating geographic needs. Deterrent factors to an optimal geographic distribution of most professionals are reviewed, along with factors specific to our residency training programs. In the short term, the benefits and limitations of recruiting foreign-trained psychiatrists are compared with those of recruiting Canadian specialists. Complementary long term strategies include the provision of financial incentives, optimal working conditions, relevant training and maintenance of competence issues, and community support.

Canada↗

Geographical distribution of dental operators in South Africa over the period 1972-1992.

Using data available on dentists for 1972, 1982 and 1992 and on dental therapists for 1992 the geographical distribution of dental operators (dentists/dental therapists) in South Africa was determined and the dental operator to population ratios were calculated. Over a period of 20 years the number of dentists in South Africa has increased by 135,6 per cent while the total population of the area has increased by 59,8 per cent. The lowest operator to population ratio was 1:4517 found in the PWV region, and the highest ratio was 1:48730, recorded in the Northern Transvaal. The greatest decrease in dental operator to population ratios occurred in Natal and Transvaal. The study shows that there is an imbalance in the geographic distribution of dental operators favouring large urban areas.

Dentists↗

Geographic distribution and origin of CFTR mutations in Germany.

The geographic distribution and origin of CFTR mutations in Germany was evaluated in 658 three-generation families with cystic fibrosis (CF). Fifty different mutations were detected on 1305 parental CF chromosomes from 22 European countries and overseas. The major mutation. delta F508 was identified on 71.5% of all CF chromosomes, followed by R553X (1.8%), N1303K (1.3%), G542X (1.1%), G551D (0.8%) and R347P (0.8%). According to the grandparents' birthplace, 74% of CF chromosomes had their origin in Germany; the delta F508 percentage was 77%, 75%, 70% and 62% in northern, southern, western and eastern Germany, respectively. Ten or more mutant alleles in the investigated CF gene pool originated from Austria, the Czech Republic, Poland, Russia, Turkey and the Ukraine. This widespread geographic origin of CFTR mutations in today's Germany reflects the many demographic changes and migrations in Central Europe during the 20th century.

Cystic Fibrosis↗

Geographical distribution and density of Ixodes dammini (Acari: Ixodidae) and relationship to Lyme disease transmission in New Jersey.

As part of continuing studies of Lyme disease, deer were surveyed during three hunting seasons in 1981 to obtain information on geographic distribution and density of I. dammini in New Jersey. I. dammini occurred throughout central and southern New Jersey. Four deer management zones (DMZs) were shown to have high tick densities. Geographical distribution and density data were independently regressed against 25 environmental and physical factors. Elevation was shown to be the most important factor in explaining the variability in both I. dammini distribution and density. Lyme disease cases were closely associated with the distribution of I. dammini and 57.3 percent of 117 Lyme disease cases occurred in the four DMZs previously identified as having the highest tick density.

Animals↗

Determinants of dentists' geographic distribution.

Practice location may have greater economic importance today for dental students and dentists who are considering relocation and/or expansion to new sites than in the past. Yet, a literature review easily leads to the inference that practice location decisions are far too complicated and individualistic for there to be any systematic pattern of dentists' geographic distribution. This paper specifies and estimates an economic model that attempts to explain the distribution of dentists in particular market areas in the state of Connecticut and to test the hypothesis that the distribution, rather than exhibiting randomness, adheres to the prediction of theory. The findings show that the geographic distribution of dentists is significantly related to a few key variables. Given these results, and because this model can be applied to other areas and uses data that are readily available for any market area, it may be useful for educators involved in helping dental students with their practice location decisions.

Capital Financing↗

Geographical distribution of certain cancers in South Africa, 1968-1972.

The geographical distributions of six major causes of cancer mortality in South Africa have been analysed for three population groups: White, Coloured and Asian. Because of the lack of comparable data, the majority Black population is not included. Geographical patterns are compared and discussed in the light of findings from other countries. In several cases the potential for aetiological follow-up is demonstrated.

Age Factors↗

Geographical distribution and age related prevalence of antibody to Hantaan-like virus in rat populations of Baltimore, Maryland, USA.

Recent studies indicate that domestic rats (Rattus norvegicus) from harbor-side areas within port cities of the United States are infected with a Hantaan-like virus. The geographical distribution of seropositive rats may be extremely localized within these urban environments. We surveyed four widely separated residential sites distant from the harbor within Baltimore, Maryland, USA, to determine the geographical distribution and prevalence of antibody to Hantaan-like virus in rats from urban areas of high human population density. Captured rats were weighed and examined for sexual maturity to allow some estimation of age, and their sera were examined by indirect immunofluorescent antibody assay for antibody to Hantaan virus. Seropositive rats were found at all four sites within Baltimore. Increasing antibody prevalence and high titers were associated with increasing rat weight and sexual maturity. Our results show that infection of rats by a Hantaan-like virus is widespread in Baltimore. Antibody in rats may be due to infections acquired during maturation or the delayed seroconversion of rats infected prior to weaning.

Age Factors↗

Geographic distribution of constipation in the United States.

OBJECTIVE: Despite its frequent occurrence, the etiology of constipation has remained poorly understood. The influence of widely accepted risk factors such as inadequate dietary fiber intake, immobility, insufficient fluid intake, and poor muscle tone is unclear. This study examined the geographic distribution of constipation among Medicare beneficiaries to identify potential environmental risk factors. METHODS: All Medicare beneficiaries with a diagnosis of constipation were extracted from the total Health Care Financing Administration data file of 1987 and stratified by sex, race, and state of residence. The population of each state by sex, race, and age >65 yr served as the denominator to calculate sex- and race-specific morbidity rates. RESULTS: A distinct geographic distribution was observed. When stratified by individual states, hospital discharges for constipation were more common in rural as compared with urban states. Constipation also appeared to be more common in northern and in poorer states. CONCLUSION: The distinct geographic pattern of constipation suggests the influence of three global environmental factors: rural living, colder temperature, and lower socioeconomic status.

Aged↗

Mycetomas in Mali: causative agents and geographic distribution.

Although Mali is situated in the African zone endemic for mycetomas, no report has been published on the characteristics of the disease in this country. We report a series of 54 cases observed in Bamako. The causative agents were Madurella mycetomatis in 20 patients, Leptosphaeria sp. in one patients, Actinomadura madurae in 12 patients, A. pelletieri in 15 patients, and Streptomyces somaliensis in three patients. In this series, the observed geographic distribution of the causative agents was in agreement with data on the causative agents and their geographic distribution in neighboring countries, and with those suggesting a relationship between the type of infectious agent and the annual rainfall.

Adult↗

The geographic distribution of foreigners in West Germany.

A review of the geographic distribution of the 5 million foreigners resident primarily in the urban areas of the Federal Republic of Germany is presented. "Economic trend surface and mixed space-time interaction models were chosen to analyse the changing distribution from 1964 to 1981." The results suggest that the settlement of foreigners in the 1960s was primarily influenced by job opportunities, whereas immigrants in the 1970s were more spatially diffused down the urban hierarchy. In 1981, "first-order spatial and temporal interaction or contagion effects are significant in determining the settlement pattern. The general south to north latitudinal settlement trend is weakening over time as migration responds less to distance (intervening opportunity) and more to local economic factors, immigration legislation, family reunification, and local contagion effects." (summary in FRE, GER)

Culture↗

[The geographical distribution of genetic variants of the tick-borne encephalitis virus].

Geographic distribution of 185 tick-borne encephalitis (TBE) virus strains isolated in 8 physico-geographic areas and classified into six genetic variants was analysed. The strains of genetic variant I homologous to the Sophyin prototype strain were found to occur predominantly in the Far East and also frequently found in Western and North-Western parts of the East European plain. The vast territories from lake Baikal in the East to Ukraine in the West harbor mostly the strains significantly different from the Far-Eastern Sophyin strain. Hybridization experiments with oligonucleotide probes specific for the Neudorffle strain showed that the strains genetically similar to the virus of central European encephalitis occurred also in Eastern Europe and Western Siberia. It is concluded that a relationship exists between genetic types of TBE virus and their geographic origin.

Animals↗

[Projected supply and geographic distribution of dentists in Taiwan for the year 2000].

Using the data from the Dentist Masterfile of the Department of Health, Executive Yuan, and the reports from all Colleges of Medicine in Taiwan and the Ministry of Defense, this study projected the future supply of dentists as well as their geographic distribution. The components of projection included studying current supply, future increment and loss. The results of this study showed that there would be 7897 active dentists in Taiwan by the year 2000, or 36 dentists per 100,000 population. It also showed the poor geographical distribution of dentists will not substantially ameliorate in response the rapidly increasing supply of dentists. The 14 to 1 ratio of the highest to the lowest (Taipei city V.S. Penghu county) in terms of dentist-population will remain in the coming decade. Finally, this study discussed the projection process as well as the implications for dentist manpower policy in Taiwan.

Adult↗

Analysis of the geographical distribution of anesthesia manpower in the United States.

The 1970 geographical distributions of total anesthesia manpower, anesthesiologists, and nurse anesthetists by state were analyzed by multiple regression to account for their unevenness. Independent variables included factors relating to prior professional contact in the state, professional satisfaction, practice income, demand for services, and environment. The distribution of training programs accounted for 41 per cent of the variance in the distribution of total manpower, but 55 per cent was explained by the number of operations, location of nurse anesthesia schools, and proportion of total state employment in service occupations (a proxy for the availability of consumer services). Location of training programs and the absence of the other type of personnel were good predictors for the manpower subgroups. The distribution of nurse anesthesia schools, anesthesiologists, number of surgical operations, and the relative value schedule conversion factor together accounted for 60 per cent of the variance in the nurses' distribution. The location of residency programs (or positions) was a better predictor for the anesthesiologists' location than medical schools or factors characterizing the demand for services. The distribution of nurse anesthetists, hospital cost per day (considered a proxy for a satisfying professional life and for regionalization of services), and residency programs explained 81 per cent of the variance in the anesthesiologists' distribution. Although the regression predicts that increasing the number of residency programs in an underserved state should be associated with an increase the number of anesthesiologists, such a policy may be infeasible dur to pending federal health manpower legislation unless matched by decreasing a greater number of programs in relatively oversupplied states.

Anesthesiology↗