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PubMed1956

The insecticides; their hazard in industry and in the home.

Chemical, pharmacologic and toxicologic properties of the chlorinated hydrocarbon and organic phosphate insecticides have been reviewed. The chlorinated group present problems if there is either acute or chronic exposure, whereas the problems associated with the organic phosphates develop only in event of acute exposure. Chlorinated hydrocarbon insecticides accumulate in body fat depots and cause both liver and kidney damage while being metabolized and excreted. Organic phosphates destroy cholinesterase and produce effects related to overstimulation of the cholinergic branch of the autonomic nervous system. Barbiturates control the convulsions produced by the chlorinated hydrocarbon insecticides. Atropine blocks most of the effects of the organic phosphate insecticides. These compounds may be grouped in the following order of decreasing toxicity: TEPP, HETP, parathion, OMPA, ENP, aldrin, chlorophenothane, toxaphene, gamma benzene hexachloride, malathon and chlordane.

Aldrin↗
PubMed1956

The insecticides; their hazard in industry and in the home.

Within the past decade the chemist has evolved a new group of insecticides having a greater range of toxicity to insects-and to man. Since their use is ubiquitous, it is imperative that information be widely disseminated regarding proper cautionary measures as well as the early signs and symptoms of toxicity.

Humans↗