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At least 73 records · Page 4Linked to original sources
PubMed1976

Laryngeal neoplasm mortality in Oklahoma: 1950-1970.

A survey of death certificates of victims with laryngeal cancer in Oklahoma for the period 1950 to 1970 attempts to corroborate findings of the current literature. Sex-race specific death rates per 100,000 for white, nonwhite, and American Indian populaces displayed a distinct sex and racial pattern: respectively, 38.52, 28.11, and 12.52 for males; 5.25, 1.23, and 0 for females. Age-adjusted death rates per 100,000 for white males for the four consecutive five-year periods were 19.00, 21.64, 20.91, and 26.81; these rates show constant mortality for laryngeal cancer for the period between 1950 and 1965, followed by an increase of approximately 30% in the 1966 to 1970 interval. Similar analysis of the white females, nonwhite males, and nonwhite females did not reveal such a clear secular pattern, although the adjustment for age did preserve the sex and racial pattern indicated above. Age-adjusted laryngeal cancer death rates of 42.34, 46.14, and 48.51 for the rural, nonmetropolitan, and metropolitan counties, respectively, indicated a direct association between mortality and degree of urbanization. All findings appeared to be in concordance with those given in the recent literature.

Adult↗
PubMed2000

[Usefulness of chromosome alteration analysis in cell lines derived from laryngeal tumors for evaluation of laryngeal neoplasms].

A classical cytogenetic analysis was applied to analyse karyotypes of 9 cell lines derived from laryngeal cancer. The most frequent aberration was a deletion of the whole sex chromosome Y. An abundance of somatic chromosome alterations was further analysed to find correlation with tumour staging and grading. A conventional cytogenetic analysis seems to be not sufficient to recognize chromosome alterations specific for a given tumor stage. On the other hand, an analysis in respect to histologic grading has indicated for an association between rearrangement of 9 chromosome and a high tumor aggressiveness. It seems that a combination of conventional cytogenetics with molecular methods (FISH, CGH) would be helpful in diagnosing of laryngeal cancer.

Cell Line↗
PubMed2000

[The effect of selected factors on the course of wound healing after surgery for laryngeal neoplasms].

Finding of the a etiologic factors and participation of bacteria flora in wound healing in laryngeal cancer treatment was the purpose of our study. Investigations were performed in 27 patients. Swabs were taken from the postoperative wounds. Detailed identifications of the bacteria flora and antibiotic susceptibility of bacteria were performed. Wound healing was estimated according to extension of the carcinoma, applied antibiotics, state of the oral cavity, the kind of bacteriological flora isolated after surgical treatment from postoperative wounds. It was found that wound healing depended on the extension of carcinoma, as well as, type of isolated bacteria and antibiotic therapy used. The proper healing of postoperative wounds was not dependent on the state of the oral cavity and the dentition. The main cause of postoperative complication of wounds was methicillin-resistant Staphylococcus aureus (MRSA).

Aged↗
PubMedDate not supplied

[Contact laser microsurgery in laryngeal neoplasms].

Basing on the results obtained in 129 patients with benign and 135 ones with malignant laryngeal tumors the author provides theoretical and practical grounds for introduction of high-energy YAG laser under contact regimen in endolaryngeal microsurgery of relevant tumors. Advantages of the method, indications and contraindications to its application are considered in detail.

Adolescent↗
PubMed1995

[The prognostic value of modified quantitative classification and expression of monoclonal antibodies against PCNA in laryngeal neoplasm (introduction)].

In clinical practice there are no sufficient histopathological and immunohistochemical parameters to predicting progression of laryngeal cancer. We applied the new quantitative Anertoha, Blatsakisa and Luny cancer classification and expression of PCNA (proliferating cell nuclear antigen) to clinical findings to appreciate prognosis in laryngeal cancer.

Biomarkers, Tumor↗