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[Repetitive skin testing in patients with lower leg eczema and leg ulcer].

16 patients with lower leg dermatitis and venous ulcers had been subject to patch-testing during 1974 to 1977. When retested in 1982, the number of positive reactions per patient increased from 3.82 to 5.87 on an average. 54% of the positive epicutaneous test reactions could be reproduced in the repeated patch test. Meanwhile, 9 of 16 of patients were free of lower leg dermatitis and 8 of them were free of venous ulcers. This paper deals with the problematic nature as well as the likely causes of the apparent inconsistency of epicutaneous test reactions in patients with lower leg dermatitis and venous ulcers.

Allergens↗

[Cutaneous expansion at the level of the lower limbs. Surgical technique, indications and complications].

Skin expansion in the lowers limbs has been described for a long time. The authors report their experience in this site. The operating technique is described in such a way as to limit complications to a minimum. The indications for this technique are recalled with particular emphasy on the use of expansion in preparation for a subsequent procedure. Lastly, the most frequent complications are discussed together with the methods of their prevention.

Adult↗

[Pretibial epidermolysis bullosa. A rare form of epidermolysis bullosa simplex].

INTRODUCTION: Pretibial epidermolysis bullosa had been classified as a rare localized form of autosomal dominant dystrophic epidermolysis bullosa. OBSERVATION: We report a sporadic case of a patient suffering from bullous lesions induced by minor trauma on pretibial skin. The lesions healed with atrophic scars. No milia formation was observed. The mapping of dermoepidermal junction by LH 7:2 and GB3 monoclonal antibodies was normal. By electron microscopy, numerous perinuclear vacuoles were observed and the cleavage occurred within the basal keratinocytes. DISCUSSION: This patient had clinical features in accordance with a diagnosis of pretibial epidermolysis bullosa. However, in contrast to previous case reports, the ultrastructural pattern was this of an epidermolysis bullosa of simplex type.

Adult↗