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Taiei Miura and Franco-Japanese friendship in psychiatry.

Japanese medicine enthusiastically adopted many aspects of Western medicine, especially German, during and after Japan's modernization. After the war, the policy giving priority to German medicine changed greatly, and American medicine replaced German medicine in postwar days. Some people, however, question whether it is proper to get medical information one-sidedly from a single country. Faced with the situation of whether German or American medicine should occupy the dominant position in Japan, some doctors chose to establish ties with French medicine. Professor Taiei Miura (1901-1995) re-established an intimate relationship, broken off during the war, in the medical field between Japan and France. Much information was to be learned from French medicine, particularly in clinical neurology and psychiatry. In this essay, we relate the details of how Miura became interested in French medicine, went to study in France, then contributed greatly to Franco-Japanese friendship.

France↗

Non-prescription medicines: prescribing legislation.

This article discusses developments in prescribing legislation in relation to non-prescription medicines. The three supply categories are outlined: prescription only, general sale list, and pharmacy medicines. Changes in legislation towards increased availability of medicines that do not require prescription are covered and the implications for at-risk groups are discussed. A table of minor ailments and their principal treatments is provided.

Complementary Therapies↗

Connecting healthcare providers. An effective computer network can create durable relationships.

Physician networks are computerized systems that link primary care physicians and specialists to one another and to hospitals and other providers. The networks have four key components: communication, practice management, practice marketing, and diagnostic testing capabilities. Advantages of physician networks for hospitals include increased physician loyalty and increased market share through additional admissions and outpatient registrations. From physicians' perspective, networks can help them expand their patient bases and increase revenue, provide additional services for existing patients, automate their offices, and improve their administrative efficiency. Networks also affect the way physicians practice medicine. Changes in practice patterns improve patient care, speed test results, and improve physicians' relationships with each other and their patients. They also save time for physicians and their staff. In deciding whether to develop a network, executives must examine the architectural framework and components they need, their commitment to physician relations, how reliant they are on primary care referrals, the competitive environment, the resources they are willing to commit, legal issues, and the physicians' role in planning.

Catholicism↗

Efficiently-run practices--ways to keep costs in line.

Containment of health care costs is a serious concern today for everyone, including the local, state and federal governments, industry and the private sector. Physicians are looked at as the "bad guys" in the cost containment battle as publicity focuses on the high cost of office visits, procedures, tests and hospital charges. When you add to that the additional image of the "rich doctor," it is easy to understand why so much attention is paid to the doctor as the perceived reason for the high costs of care. Medical practices are also guilty of fostering that image as patients perceive an inefficient approach about the business side of medicine. And, as an inefficient office usually adds to a practice's overhead, someone must be expected to cover that extra cost. That someone, unfortunately, is the patient--either by a direct payment of increased fees or by the added cost of the insurance premium. What follows are some basic items of good business management that should help cut your practice expenses, whether you are solo or part of a group practice. The streamlining of your practice should enable you to keep your costs--and your fees--in line. And, as medicine changes with health maintenance organizations and preferred provider organizations becoming more of a factor, it will be essential for your practice to be cost efficient to compete.

Cost Control↗

[Telemedicine collaboration between the Rikshospitalet and the Ulleval hospital].

BACKGROUND: During the last two years the Intervention Centre at the Nation Hospital of Norway and Ullevål Hospital have pursued a research programme in telemedicine aimed at exploring the potential of inter-hospital collaboration. MATERIAL AND METHODS: Both hospitals established a communication network between operating rooms and lecture halls. Sound and video from minimally invasive surgical and radiology procedures were transmitted on a wide bandwidth ATM network (34 Mbits/s) to gain experience with the use of telemedicine for educational purposes and the treatment of patients. RESULTS: Evaluations of technical off-line and clinical line transmissions have given us helpful information about the potential of telemedicine and what it will take to utilise this potential. With the MPEG2 standard, a wide bandwidth network yields sufficient sound and image quality for educational and clinical collaboration. However, multimedia communication requires changes in the organisation to secure quality of service in relation to technical management and telemedical production. INTERPRETATION: Inter-hospital collaboration on telemedicine may be a resource in clinical practice, facilitating professional enhancements, particularly in surgery, radiology and internal medicine. Changes in the organisation are needed, but they are feasible.

Computer Communication Networks↗

[Present state and future of the self-test in preventive medicine].

The preventive medicine changes from secondary prevention of early detection and early treatment to primary prevention of the avoidance of pathopoiesis and health-Crisis. In present state, there is no a clinical laboratory which should respond to this proposition of the fact with the convention at all. As well as clinical laboratory in the hospital, the clinical laboratory in preventive medicine has also been centralized to the Health screening facilities. The immediacy of The clinical laboratory which can be measured, when it wants to measure it, Is required in order to grasp "bio-information" for avoiding the crisis of the disease. It become important that simultaneously, some relating inspection items are measured a case in which it wants to attempt. It waits for the possibility of a disease state grasp from the self measuring device that it is convenient and that the accuracy is high for health-crisis and pathopoiesis avoidance as a primary prevention in order to rapidly improve the accuracy of the weather forecast by the launch of the meteorological satellite.

Clinical Laboratory Techniques↗

Zagreb University School of Medicine: students grades during war.

AIM: To investigate whether examination grades of the students at the Zagreb University School of Medicine changed during the 1991-1995 war in Croatia. METHODS: The retrospective descriptive study included examination grades from 5 major courses in the first 5 years of the medical studies: Anatomy (first year), Physiology (second year), Pathology (third year), Internal Medicine (fourth year), and Surgery (fifth year). We compared the war-period (1991-1995) with two control periods: before (1989-1990) and after the war (1996-2000). The passing grades at the Zagreb University range from 2 to 5, with 2 as the lowest and 5 as the highest grade. There were a total of 17,682 examinations from the 5 courses in the studied periods. RESULTS: Grades were higher in the pre-war and post-war periods than in the war period (p<0.001 for both comparisons). Grades in the individual courses followed the general trend, except for the surgery course, where grades during the war were better than in the control periods, and the physiology course, where continual worsening, irrespective of the war, was observed. CONCLUSION: Medical students obtained significantly lower grades in 5 major courses during the war than before or after it. Thus, it is reasonable to assume that different factors, some related and some unrelated to war, could have adversely influenced students performance.

Croatia↗

[Fundamental curriculum in University Education of Medical Technologists: special practice for clinical medicine and biotechnology].

This is the summary of my talk about the new concept of education for medical technologists. In Osaka University, the course for laboratory medicine changed from a 3-year to a 4-year training course, and our faculty started a new curriculum of special practice in clinical medicine and biotechnology for first-year undergraduate students from 1997. This special practice in clinical medicine consists of three parts, encompassing learning in the essential divisions of the hospital, bedside learning, and presentation in case conferences. Students visit from time to time to seven divisions, outpatients' clinic, surgical operation room, laboratory for radiological examination, rehabilitation rooms, pharmacy, central storage room for medical records, and the department of medical informatics. The aim of this round practice is to broaden their review of clinical medicine. They also go to the bed side of one patient in the ward for 4 weeks especially for learning about values of laboratory data. They follow up the laboratory data and go with the patient to clinical physiological examinations. Finally, they present their case to all their teachers and class mates in a semi-congress style and are evaluated with scores by the staffs.

Biotechnology↗

[Investigation on interactions of rutin and chloramphenicol with beta-cyclodextrin using capillary electrophoresis].

The interactions of two medicines of rutin and chloramphenicol with beta-cyclodextrin were investigated using mobility shift method by capillary electrophoresis. The size of the capillary column was 37 cm x 50 microm i.d. with an effective length of 30 cm. The running buffer was a mixture of 25 mmol/L sodium borate and 100 mmol/L boric acid (pH 8.6). Effective mobilities of the two medicines changed with altering the concentration of beta-cyclodextrin. By nonlinear least square fitting curve, the inclusion constants of 98.5 and 1 204 L/mol for rutin and chloramphenicol were obtained at 25 degrees C, respectively. The inclusion constants at different temperatures were determined, from which a series of thermodynamic parameters were derived. Experimental results show that an obvious relationship of mutual compensation between enthalpy and entropy existed in these inclusion reactions. The most stable configurations of the inclusions were calculated using MM2 force field, and the results were well in agreement with the experimental results.

Chloramphenicol↗

The build-up of clinical science.

In the years 1720-1820 medicine changed from an art into a science. The slow construction of clinical science, a process still to be completed, has many founding fathers. Here the transition is analyzed through the biographic studies of John Hunter (1728-1793), Domenico Cotugno (1736-1824) and Pierre Joseph Desault (1738-1795) who respectively taught in London, Naples and Paris. Because of their scientific stature they were able to plan, build and foresee the impact of these changes.

Education, Medical↗

Traditional and evolving concepts in medical ethics.

Modern developments in science, technology and medicine have resulted in an unprecedented interest in ethical and moral issues in the practice of medicine. Changes threaten to erode the traditional ethos of practice and to transform medicine into a marketable commodity. The challenge of a new medical ethic and suggestions for a future course are discussed.

Africa, Southern↗

[What did hormonal contraception change for women?].

A major date and a major change for our society, hormonal contraception had to battle against law and against medicine. Changing women's status, it gave them a new freedom. But what of the traditional role models, man and woman's relationship to each other, what of their approach to love and sexuality? That is the question...

Contraceptives, Oral, Hormonal↗

[Bibliometric repercussions of adopting English as the sole language for publication].

OBJECTIVE: To determine the effect that the change from French to English had on the impact of the Annales de l' Institut Pasteur. THEORETICAL REFERENCE: The Pasteur Institute journals have a prestige of over 100 years of existence and eight Nobel Prize winners in Physiology and Medicine. Changes through time on the impact of these journals can be monitored as they are included in databases of the ISI (Institute for Scientific Information). METHODS: A year by year analysis from 1974 to 1992 was done using simple regression between percentage of articles published in English and: a) their impact factor; b) their ranking among journals of the same field. RESULTS: The determination coefficient (r2) between the percentage in English and the impact factor was 0.108, and that between percentage in English and the journal's rank in similar publications was 0.178 for the Ann Microbiol, 0.045 for the Ann Immunol and 0.122 for the Ann Virol. CONCLUSIONS: The change of language did not increase the impact factor of the French journals.

Academies and Institutes↗

[Long-term administration study of propiverine hydrochloride (BUP-4 tablets) in pollakiuria and urinary incontinence].

The safety and efficacy of one-year administration of propiverine hydrochloride (BUP-4 tablets) were assessed in facilities affiliated with the Department of Urology of Yokohama City University School of Medicine. Changes in subjective symptoms showed significant improvement in mean frequency of urination in the daytime from 10.3 +/- 4.0 times before administration to 7.1 +/- 2.9 times 1 year after the start of administration, in mean frequency of voiding at night from 4.2 +/- 1.7 times to 2.1 +/- 1.1 times and in mean incidence of urinary incontinence from 2.9 +/- 2.1 times to 0.7 +/- 1.0 times. The final degree of overall improvement rate was 82.0% (41/50 cases). Adverse effects were observed 26 times in 22 patients, the incidence being 15.6% (22/141 cases). They consisted of digestive symptoms in 9.9% (6 events of dry mouth, 4 of constipation, 2 of abdominal discomfort, 2 of diarrhea and 1 of gastritis), urinary tract symptoms in 3.5% (4 of dysuria and 1 of residual urine), abnormal laboratory findings in 1.4% (increase in glutamic-oxaloacetic transaminase, glutamic-pyruvic transaminase or lactate dehydrogenase levels) and others (1.4%). These results provide further evidence of the safety and efficacy of propiverine hydrochloride (BUP-4 tablets) even when administered for a long-term in the treatment of patients with pollakiuria and urinary incontinence.

Administration, Oral↗

Acoustic ejection mass spectrometry: the potential for personalized medicine.

INTRODUCTION: The emergence of personalized medicine (PM) has shifted the focus of healthcare from the traditional 'one-size-fits-all' approach to strategies tailored to individual patients, accounting for genetic, environmental, and lifestyle factors. Acoustic ejection mass spectrometry (AEMS) is a novel technology that offers a robust and scalable platform for high-throughput MS readout. AEMS achieves analytical speeds of one sample per second while maintaining high data quality, broad compound coverage, and minimal sample preparation, making it an invaluable tool for PM. AREAS COVERED: This article explores the potential of AEMS in critical PM applications, including therapeutic drug monitoring (TDM), proteomics, metabolomics, and mass spectrometry imaging. AEMS simplifies conventional workflows by minimizing sample preparation, enhancing automation compatibility, and enabling direct analysis of complex biological matrices. EXPERT OPINION: Integrating AEMS with orthogonal separation techniques such as differential mobility spectrometry (DMS) further addresses challenges in isomer discrimination, expanding the platform's analytical capabilities. Additionally, the development of high-throughput data processing tools could further enable AEMS to accelerate the development of personalized medicine.

Humans↗

Probable future funding priorities in maternal and child health: a modified Delphi National Survey.

Recent enactment of program consolidation block grants proposed by the Reagan administration has left many observers of public health services wondering about the impact of such a change on categorical programs in maternal and child health (MCH). This study first presents predictions about the future of 23 specific MCH services, derived from a modified Delphi Survey of MCH experts, and then examines the implications of these predictions for future public health.

Adult↗