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At least 73 records · Page 4Linked to original sources

PubMed2000

Effect of a water extract of Moringa oleifera seeds on the hydrolytic microbial species diversity of a UASB reactor treating domestic wastewater.

The effect of a continuous supply of a water extract of Moringa oleifera seeds (WEMOS) on the hydrolytic microbial population of biomass grown in mesophilic upflow anaerobic sludge blanket reactors treating domestic wastewater was investigated. The WEMOS-treated sludge had seemingly a wider diversity, with enterobacter and klebsiella as dominant hydrolytic bacteria, compared with the control sludge. Additional tests indicated that various hydrolytic bacteria could degrade WEMOS. It appeared that a continuous supply of WEMOS to an anaerobic digester, treating domestic wastewater, increased the diversity of hydrolytic bacteria and therefore enhanced the biological start-up of the reactor.

Bacteria↗

PubMed1999

Amplified fragment length polymorphism (AFLP) analysis of genetic variation in Moringa oleifera Lam

Moringa oleifera is an important multipurpose tree introduced to Africa from India at the turn of this century. Despite limited knowledge of the levels of genetic diversity and relatedness of introduced populations, their utilization as a source of seed for planting is widespread. In order to facilitate reasoned scientific decisions on its management and conservation and prepare for a selective breeding programme, genetic analysis of seven populations was performed using amplified fragment length polymorphism (AFLP) markers. The four pairs of AFLP primers (PstI/MseI) generated a total of 236 amplification products of which 157 (66.5%) were polymorphic between or within populations. Analysis of molecular variance (AMOVA) revealed significant differences between regions and populations, even though outcrossing perennial plants are expected to maintain most variation within populations. A phenetic tree illustrating relationships between populations suggested at least two sources of germplasm introductions of Kenya. The high levels of population differentiation detected suggest that provenance source is an important factor in the conservation and exploitation of M. oleifera genetic resources.

Journal Article↗

PubMed1998

Niaziminin, a thiocarbamate from the leaves of Moringa oleifera, holds a strict structural requirement for inhibition of tumor-promoter-induced Epstein-Barr virus activation.

Three known thiocarbamate (TC)- and isothiocyanate (ITC)-related compounds have been isolated from the leaves of Moringa oleifera, a traditional herb in southeast Asia, as inhibitors of tumor promoter teleocidin B-4-induced Epstein-Barr virus (EBV) activation in Raji cells. Interestingly, only niaziminin among 10 TCs including 8 synthetic ones showed considerable inhibition against EBV activation. The structure-activity relationships indicated that the presence of an acetoxy group at the 4'-position of niaziminin is important and indispensable for inhibition. On the other hand, among the ITC-related compounds, naturally occurring 4-[(4'-O-acetyl-alpha-L-rhamnosyloxy)benzyl]ITC and commercially available allyl- and benzyl-ITC significantly inhibited activation, suggesting that the isothiocyano group is a critical structural factor for activity.

Cell Line↗

PubMed1989

Structure of a mutagen from roasted seeds of Moringa oleifera.

A mutagenic compound was isolated from roasted seeds of Moringa oleifera Lam. Its structure has been elucidated by spectral analysis as 4(alpha-L-rhamnosyloxy)phenylacetonitrile. The results of the Micronucleus Test, an in vivo method, showed that the number of micronucleated polychromatic erythrocytes (PCE)/1000 PCE for this compound is higher than that of the solvent control, dimethylsulfoxide, and approximates that of the positive control, tetracycline. This indicates that 4(alpha-L-rhamnosyloxy)phenylacetonitrile is a genotoxic compound.

Acetonitriles↗

PubMed1987

Effect of water coagulation by seeds of Moringa oleifera on bacterial concentrations.

The effects of a Sudanese water purification method traditionally used in Sudan to treat turbid waters were studied with respect to turbidity reduction and removal of faecal indicator bacteria as well as selected enteric bacterial pathogens. Water treatment was performed at 30 degrees C with Moringa oleifera seed material as a coagulant, and the technique employed corresponded closely to that used to clarify turbid water in Sudanese villages. A turbidity reduction of 80.0-99.5% paralleled by a primary bacterial reduction of 1-4 log units (90.00-99.99%) was obtained within the first 1 to 2 h of treatment, the bacteria being concentrated in the coagulated sediment. During the 24 h observation period a secondary bacterial increase due to regrowth in the supernatant water was consistently observed for Salmonella typhimurium and Shigella sonnei, in some cases for Escherichia coli, but not for Vibrio cholerae, Streptococcus faecalis and Clostridium perfringens. The potential of the method when compared with some alternative for the improvement of rural drinking water supplies is discussed.

Disinfection↗

PubMedDate not supplied

Uterine histoarchitecture during pre and post-implantation periods of rats treated with aqueous extract of Moringa oleifera Lam.

The effect of aqueous extract of Moringa oleifera Lam. (roots) has been studied on histoarchitecture of the uterus during pre and post-implantation stages in rats so as to elucidate its antifertility mode of action. The histoarchitecture of the uterus of control pregnant rat had revealed a clear-cut close apposition of the uterine endometrium with reduced lumen and loose stroma. There was a prominent appearance of deciduoma and the uterine glands were enlarged. Glandular cells showed hypertrophy and in the endometrium the leucocytic infiltration was increased. When the aqueous extract of M. oleifera Lam. was administered, no deciduoma was observed on day 5th of pregnancy and the luminal epithelium remained unstimulated. The lumen was enlarged and the uterus was non-oedematous. It has been concluded that the administration of aqueous extract of M. oleifera Lam. to pregnant rats could not stimulate the uterus which remained non-receptive throughout the period of treatment, therefore, the fertilized eggs may not be welcomed by the unprepared uterus.

Abortifacient Agents↗

PubMed1957