Chemotherapy in skeletal tuberculosis.
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The results of a computerized study of 652 cases of bone and joint tuberculosis were presented. The cases were studied according to a program of 76 variables. From the various results of such a study, the following data were found. A high rate of tuberculous osteomyelitis (19%) and of tuberculosis of the upper limb joints (14%) were found. The reliability of a new x-ray classification based on the degree of destruction of the joint should be emphasized along with the reliability of biological examinations. All patients were treated according to the same principles; chemotherapy against tuberculosis, and surgical measures against musculoskeletal destruction. The results were excellent for tuberculosis. A favorable response to chemotherapy was found in 98% with only 3% of the cases relapsing. Anatomical results were surprisingly good and excellent in 56% of the cases, in spite of the low rate of surgery performed. Fair anatomical results often gave good functional results if no deformity persisted.
Localisation of tuberculosis in the hand is a rare entity. We report here on 45 cases representing 7% of 650 cases of tuberculosis of the musculoskeletal system treated in our clinic during the past 16 years. Localisation in a joint or tendon sheath is classic but some others such as osteitis (8 cases) or soft tissue lesions (3 cases) have been seen, so the diagnosis must be proved bacteriologically by demonstrating the presence of the tubercle bacillus or, more often, histologically. A prolonged clinical course before the patient seeks medical advice is common and the clinical manifestations are numerous. Some patients were treated with a classical one year regimen. More recent cases have been treated with a short six month regiment. A comparison of the effectiveness of the two regimes is made.
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OBJECTIVE: To identify the most common health issues diagnosed by general practitioners in newly arrived African refugees. DESIGN: Descriptive study based on a purposive sample of six GPs to collate data from medical records of patients from African countries who had attended their clinics for the first time between 1 January and 30 June 2005. SETTING: Two community health centres and two private general practices in metropolitan Melbourne. PARTICIPANTS: African refugee patients who arrived in Australia after 1 June 2004 and were seen by the six participating GPs between 1 January and 30 June 2005. MAIN OUTCOME MEASURES: Demographic characteristics, laboratory test results and final diagnoses. RESULTS: Data were collected from 258 patient files. Most patients were from Sudan (57%) or Liberia (17%). Half were aged under 15 years. The most common health problems identified were inadequate vaccinations, nutritional deficiencies (vitamin D and iron), infectious diseases (gastrointestinal infections, schistosomiasis, and latent tuberculosis) and dental disease. Musculoskeletal, psychological and social problems were common in adults. 37% of patients were tested for latent tuberculosis, and 25% of these tested positive. CONCLUSIONS: African refugees require comprehensive health assessments for undiagnosed and untreated health problems. While most of the common diseases identified are non-communicable, if left untreated they will affect the long-term health and productivity of new settlers.
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