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At least 73 records · Page 4Linked to original sources
PubMed1989

Pseudocyst or cystic neoplasm? Differential diagnosis and initial management of cystic pancreatic lesions.

Owing to advances in pancreatic imaging, cystic lesions of the pancreas are being recognized with increasing frequency. A presumptive diagnosis of "pseudocyst", based upon CT appearance alone, will prove to be in error in as many as one-third of patients. Neoplastic cysts of the pancreas are particularly susceptible to this misdiagnosis, which can result in inappropriate drainage rather than resection. Using a combination of historical features and computed tomography, the differential diagnosis between pseudocyst and cystic neoplasm can usually be made. In borderline patients transcutaneous aspiration for cytology, and analysis of the cyst fluid for neoplastic markers may prove helpful. Final resolution of doubtful cases is achieved by biopsy of the cyst wall.

Adenocarcinoma↗
PubMed1998

[The use of computed and magnetic resonance tomography in the diagnosis of neoplasms of the pelvic bones and sacrum].

The experience of the computed tomography (CT) application in the pelvic bones and sacrum tumors diagnosis in 46 patients was summarized. The data obtained were defined more precisely using magnet-resonance tomography (MRT). MRT in contradistinction to permits to differentiate the soft tissues and reveal the tumoral invasion of dura mater and the spinal cord substance, the spinal cord nerves affection. Using CT it is possible to estimate more accurately the bone structure and tumoral elements, containing calcium.

Bone Neoplasms↗
PubMedDate not supplied

Thin needle biopsy as a routine method for rapid diagnosis of neoplasms.

The present communication demonstrates the possibility of applying the "thin needle biopsy" as a routine method for rapid cytologic diagnosis of neoplasms. Systematically used in the examination of pulmonary, mammary, and thyroid tumors, the "thin needle biopsy" offers the following advantages: 1) decreased occurrence of so-called "false negative diagnoses"; 2) psychological relief for the patient; 3) decreased cost.

Biopsy, Needle↗
PubMedDate not supplied

Fine needle aspiration cytologic findings of breast mucinous neoplasms: differential diagnosis between mucocelelike tumor and mucinous carcinoma.

OBJECTIVE: To report the cytologic findings of mucocelelike tumor and mucinous carcinoma. STUDY DESIGN: All mucinous neoplasms diagnosed by fine needle aspiration and confirmed by histologic examination were reviewed to detect the cytologic findings helpful for the differentiation. The cytologic findings were correlated with the histologic findings. RESULTS: Cytologically, mucinous carcinomas were highly cellular and showed many single epithelial cells and variably formed epithelial cell clusters in abundant extracellular mucin. Malignant cells exhibited round, atypical nuclei; granular chromatin; and small nucleoli. Mucocele like tumor showed low cellularity with scanty, monolayered, small sheets of epithelial cells and abundant, extracellular mucin. Myoepithelial cells were present within the epithelial cell sheets. Tumor cells were usually small, with uniform, round nuclei; fine chromatin; and absence of nucleoli. CONCLUSION: Cytologic findings of mucocelelike tumor and mucinous carcinoma were different in cellularity, shape of cell clusters and nuclear features, although mucocelelike tumors having a carcinoma component were similar to mucinous carcinoma. Awareness of the cytologic findings of breast mucinous neoplasms is important to make a specific diagnosis.

Adenocarcinoma, Mucinous↗
PubMed1991

[Significance of electron microscopy in differential diagnosis of small cell neoplasms].

The diagnosis of small cell anaplastic neoplasms is one of the difficult problems in routine pathology. In some cases, it is almost impossible by light microscopy (LM) to arrive at a correct diagnosis. Electron microscopy (EM) may contribute greatly in solving this problem. However, it is impractical to make EM examination as a routine in every difficult neoplasm. Therefore, we have reviewed, by EM specimens of 21 cases (9 cases of small cell carcinoma and 12 cases of lymphoma, previously diagnosed by LM in this hospital), and compared the light and ultrastructural features of these tumors. We found that the most important light microscopic feature to differentiate lymphoma from small cell carcinoma is the nuclear structure of tumor cells. According to the characteristics such as the shape of nuclei, the distribution of chromatin, the stereoscopic impression of nuclear section plane while focusing, the appearance of nucleoli, it is often possible to arrive at a correct diagnosis of lymphoma or small cell carcinoma by LM.

Adolescent↗
PubMed1997

Percutaneous needle biopsy diagnosis of benign neurogenic neoplasms.

Preoperative diagnosis of benign neurogenic neoplasms (BNNs) provides useful information in guiding management. To assess the effectiveness of fine-needle aspiration (FNA) and needle core biopsy (NCB) in diagnosing schwannomas and neurofibromas, 40 percutaneous biopsies interpreted as BNNs or obtained from lesions subsequently shown by excision to be BNNs were reviewed. The 13 aspirates diagnostic of BNN revealed spindle cells arranged haphazardly in irregular tissue fragments and in parallel as elongated ropy fascicles, with a myxoid to fibrillary background. The nuclei were buckled, often with intranuclear cytoplasmic inclusions. Four lesions showed nuclear pleomorphism without mitoses. Of 19 schwannomas evaluated by FNA, four (21%) were diagnosed as schwannomas and seven (37%) as BNNs. Ten neurofibromas were aspirated, revealing two (20%) BNNs. Of seven nondiagnostic FNAs accompanied by NCB, three (43%) indicated a BNN. The sensitivities of FNA, NCB, and both modalities in diagnosing BNNs were 43,60, and 71%, respectively. For the 16 FNAs showing features of BNNs, subsequent excisions revealed 11 schwannomas, two neurofibromas, one neurogenic sarcoma, one fibromyxoid neoplasm of uncertain malignant potential, and one unclassified low-grade myxoid sarcoma. FNA can be effective in diagnosing BNNs. If collagenous or myxoid lesions yield paucicellular nondiagnostic aspirates, NCB is helpful. Lowgrade sarcoma and neurofibromatous areas of neurogenic sarcoma may be misinterpreted as BNNs by percutaneous biopsy. BNNs may show nuclear pleomorphism without mitotic activity, and should not be mistaken for sarcoma.

Adolescent↗