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At least 73 records · Page 4Linked to original sources
PubMed1986

Carcinoma of the tongue and tonsil (oropharynx).

In this article, the multidisciplinary approach to the management of carcinomas of the tongue and oropharynx has been emphasized. The decision for the primary mode of therapy will depend on the multiple factors discussed herein. However, a surgeon skilled in the management of head and neck tumors, including major reconstructive techniques, should lead the team. Most patients with head and neck carcinoma present with lesions that are relatively far advanced, and the combination of surgical excision and radiation therapy has proved to be the best method of controlling this disease. Even when cure is unlikely, the palliation of the patient by proper resection and immediate reconstruction, followed by adequate radiation therapy, can provide significant palliation and, it is hoped, avoid the horribly painful and agonizing death that ensues from massive local recurrence in the head and neck. Modern reconstructive techniques allow for reasonable aesthetic and functional restoration, which can be performed in a single stage at the time of the ablation of the tumor. Healing with these well-vascularized flaps is predictable and allows the patient to get to the radiation therapist within the early postoperative period. A full tumoricidal dose of radiation therapy can then be instituted with the expectation that the reconstruction with the vascularized tissue will withstand the irradiation well. This avoids the increased complication rates associated with operating in irradiated fields and gives the radiation therapist a better chance for effective therapy with a markedly reduced tumor load. These tumors remain one of the most obstinate problems that surgeons face today. However, an aggressive approach to control local disease remains the best therapy and offers the patient the only chance for cure. These are difficult patients to manage from many aspects. I believe that the statement made by Dr. Charles Mayo in 1905 remains timely: "A large part of abdominal work is recreational as compared with the work of what might be called the heavy surgery of the neck."

Carcinoma, Squamous Cell↗
PubMed2004

Carcinoma of the oral pharynx: an analysis of subsite treatment heterogeneity.

The data indicate that SCC of the various subsites of the oropharynx can be treated successfully with acceptable locoregional control and survival rates by using either surgery or primary radiotherapy for TI or T2 primary lesions. Treatment success data for late-stage disease (T3 and T4) are less encouraging. regardless of which modality is used or which treatment center is administering treatment. This finding may suggest an intrinsic property of these lesions or the patient that may be going unnoticed.One problem is that the diversity of approaches to these lesions hinders any meaningful comparisons between series from different treatment centers. There exists heterogeneity in patient populations and approaches to staging and characterization of these diseases. This situation has ensured the same heterogeneity in treatment philosophy, which is largely institutionally based.

Carcinoma, Squamous Cell↗
PubMed1989

Parapharyngeal mass presenting with sleep apnoea.

A 60-year-old man presented with a history of progressive sleep disturbance due to an intraoral parapharyngeal salivary gland tumour. The sleep study performed post-operatively showed rapid resolution of nocturnal hypoxic episodes. This appears to be the first recorded case of a parapharyngeal mass causing sleep apnoea and we review the current literature on obstructive sleep apnoea.

Humans↗
PubMed2001

Intracranial metastases from oral squamous cell carcinoma.

We present two cases of histologically confirmed intracerebral metastases from oral squamous cell carcinoma (SCC). This site of distant spread has not to our knowledge previously been reported. The only common feature in all these cases was the long period over which the patients had untreated primary disease (12--24 months). Both patients developed symptoms from their cerebral deposit within a short time of diagnosis and treatment of the primary disease. They died rapidly of their cerebral metastases despite extensive and effective treatment of the primary site and regional lymph nodes. We recommend that a magnetic resonance (MR) scan of the brain is considered for patients who present with long-standing untreated primary oral SCC.

Brain Neoplasms↗
PubMedDate not supplied

[Analysis of epidermoid carcinomas using panoramic radiography and computerized tomography].

The purpose of this work was to compare radiographic findings, such as localization and extension of tumors toward the bone and soft tissues, in panoramic radiography and computed tomography (CT). Four radiologists assessed the radiographic findings of 48 patients with the histopathological diagnosis of squamous cell carcinoma in different sites of the maxillofacial region. Panoramic radiographs and computed tomographs were obtained at the University of Iowa Hospitals and Clinics, at FUNDECTO-USP and at the hospital of the University of São Paulo (USP). We observed a considerable limitation of the panoramic radiography in determining the localization and extension of tumors, since it revealed unclear delimitations. Regarding CT, better results were obtained: it was possible to observe the invasion of the tumor toward adjacent soft tissues, as well as the extension of bone destruction and the depth of the lesion, which were confirmed by surgical findings. We concluded that computed tomography demonstrated to be a sensitive radiographic technique for the detection of the involvement of bone and soft tissues, contributing for a more precise diagnosis, surgical planning and intervention. On the other hand, panoramic radiography was considered less sensitive and less efficient than CT, since it shows only unclear borders of the lesions and is not able to assess the involvement of soft tissues.

Carcinoma, Squamous Cell↗
PubMedDate not supplied

THE HARD palate.

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Humans↗