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Atrophic rhinitis in New Zealand white rabbits infected with Pasteurella multocida.

Atrophic rhinitis was detected in New Zealand White rabbits when upper respiratory tract disease was evaluated during a vaccine field trial for the prevention of pasteurellosis. Of 52 adult rabbits euthanatized and necropsied, 26 (50%) had evidence of turbinate atrophy. Atrophy was detected in 77% of rabbits with Pasteurella multocida infection only, 71% of rabbits with concurrent P multocida and Bordetella bronchiseptica infections, and 6% of rabbits with B bronchiseptica infection only. Grossly, turbinate atrophy was characterized by a mild to severe loss or diminution in the maxilloturbinates. Histologically, turbinate bones were small and irregular in thickness and had numerous osteoclasts and osteoblasts. A neutrophilic exudate filled the nasal passages, and infiltrates of neutrophils and lymphocytes were detected in the mucosa and submucosa of the nasal turbinates. Rhinitis was significantly (P less than 0.001) associated with turbinate atrophy. Isolates of P multocida from rabbits with turbinate atrophy were serotype A:12.

Animals↗

Pasteurella multocida infection involving cranial air spaces in White Leghorn chickens.

Seven 18-wk-old pullets from a commercial layer flock experiencing increased mortality associated with neurologic and respiratory symptoms were submitted to the California Veterinary Diagnostic Laboratory System at the Turlock Branch for necropsy. Clinical signs included depression, torticollis, swollen eyelids, conjunctivitis, and sinusitis. Meningoencephalitis and suppurative inflammation of the cranial air spaces were found on histopathology. The brain, sinuses, and air spaces of the cranium were infected with Pasteurella multocida. Complicating the condition was Mycoplasma gallisepticum infecting the sinus and paramyxovirus-I affecting the trachea.

Animals↗

An interesting case of failed renal transplant complicated by a lymphocele infected with Pasteurella multocida and a review of the literature.

Lymphoceles are a well-known complication of renal transplant surgery and can be asymptomatic or present with a variety of symptoms and complications. We describe a patient who presented with a Pasteurella multocida infection of a lymphocele which occurred 3 weeks after a course of penicillin for a cat bite and 10 months after a renal transplant nephrectomy. We also will review the incidence, predisposing factors, origin, symptomatology, diagnosis, complications, and treatments of post-renal transplant lymphoceles.

Adult↗

[Aerogenous immunostimulation of weaner swine against experimentally induced respiratory infections with Pasteurella multocida].

The clearance of Pasteurella, Bordetella and Haemophilus from the lung of weaners was increased by aerogenous immunostimulations using a lysate mixture consisting of 12 strains of 8 bacterial species, as well as live and inactivated temperature sensitive mutants of Pasteurella multocida. The severity of experimental pneumonias caused by Pasteurella has also been decreased by this treatment. The effect of the lysate was shown to be unspecific and short, as antibody production against Pasteurella was not induced and no booster effect of subsequent aerogenous immunizations with Pasteurella antigens could be detected.

Animals↗

[Studies on respiratory infection with Pasteurella multocida].

A questionnaire style survey on Pasteurella multocida infection was conducted at on 528 laboratories of hospitals. The questionnaire included the detection of Pasteurella multocida from sputum, the age distribution, underlying disease etc. of the patients. In Japan, infectious diseases caused by Pasteurella multocida were found in 179 cases in 67 (26.0%) of the 258 hospitals. The incidence of the infections tends to increase, 18 cases in 1989, 25 cases in 1990, 18 cases in 1991 (Jan.-Jul.). These 179 cases were broken down into 44 males (from 1 year old to 85 years old, mean 58.9 years old), 45 females (from 18 years old to 85 years old, mean 60.2 years old), and 90 patients whose sex was unknown. Underlying diseases were recognized in 72 cases. Diseases related to the respiratory organ were 61 (84.7%) cases. The cases of hemo-sputum had to be differentiated from malignant tumors Recurrent Pasteuralla multocida infections were recognized in 4 males and 4 females. And the 4 cases had been handling animals. There were only 26 cases who had contact with animals, the others were unknown. This result suggested that contact with animals may cause these infections. Recently, the detection of Pasteurella multocida from the sputum tends to increase. The elderly patient with chronic pulmonary disease, who is handling animals must be educated on hygiene and zoonosis.

Adolescent↗

Natural history of infection with Pasteurella multocida in rabbits.

Monitoring of rabbits at a commercial rabbitry for Pasteurella multocida infection revealed that the nares of 10 litters of New Zealand White rabbits were not colonized before weaning at 8 weeks of age, regardless of whether or not the does were infected. The earliest nasal infection was detected at 12 weeks of age, and by 22 weeks of age, 23% had P multocida infection. Rhinitis developed 2 or more weeks after infection was detected in most rabbits. A survey of 76 adult rabbits in the breeding colony revealed that 72% had P multocida infection. In 31 rabbits with rhinitis, 90% were infected, whereas in 55 rabbits with P multocida infection, only 50% had rhinitis. During the period of surveillance, there was an epizootic of rhinitis caused by P multocida. All age groups except preweanlings were affected. Serotyping of 29 isolates of P multocida revealed that 93% were somatic type 12. Surveillance of rabbits for pasteurellosis at a laboratory animal facility revealed that the following clinical syndromes developed in decreasing order of magnitude: rhinitis, conjunctivitis, abscesses, and otitis media.

Abscess↗