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[Mortality among workers in a cigarette factory in Lucca (Tuscany)].

Aim of the present cohort study was to evaluate the mortality pattern among workers in a cigar and cigarette factory in Lucca, Italy. The study followed 2341 workers (1585 women and 756 men) registered in the company payrolls and employed for at least six months from 1 January 1960 through 1 January 1994. Follow-up was between the start of employment in the factory and 1 June 2002 (totally 74363,5 person-years). For both sexes, all-causes mortality was lower than expected (men: SMR= 0.8; CI95% 0.7-0.9; 158 deaths; women: SMR= 0.9; CI95% 0.8-1.0; 584 deaths) and no excess of mortality was reported for all malignant neoplasms. Among female workers, the frequency of deaths from pleural cancer was elevated at a statistically significant level (SMR= 6.0; CI95% 2.4-12.6; 5 deaths). One death for pleural cancer also occurred among men versus 0.4 expected. All women deceased from pleural cancer had been working in tobacco manufacturing for at least 30 years. The excess of pleural neoplasms reported in this study suggests the opportunity to evaluate the risk due to asbestos use in many manifacturing industries, especially where steam was used for extractive or warming purpose.

Adolescent↗

Pulmonary neoplasms simulating interlobar pleural effusions.

Loculated pleural effusions simulating neoplasms are a well known pitfall. The reverse is less well recognized. We describe three cases where tumours were initially diagnosed as loculated effusions. The differentiation of these two entities is discussed.

Diagnosis, Differential↗

[T lymphocytes in the circulating blood and pleural fluid of patients with tuberculosis or cancer].

Inflammatory pleurisies in the adult are particularly rich in CD4 lymphocytes, capable of inducing and facilitating the immune reaction. The aim of this study was to determine the percentage of CD4 and CD8 lymphocytes in pleural fluid and blood in 13 patients with tuberculous pleurisy and 12 patients with pleural neoplasms, to establish the diagnostic value of this analysis. Independent of the etiology of the effusion there is a concentration of CD4 T lymphocytes in the pleural fluid compared to the blood (49.52 +/- 12.36% and 39.28 +/- 6.74%, respectively, p value less than 0.001). However, there was a similar concentration for the two types of disorders studied with 59.92 +/- 7.26% for tuberculous pleurisies and 45.83 +/- 6.26% for neoplastic effusions, thus this technique does not make the diagnostic orientation any clearer.

Adult↗