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[Age and sex characteristics of the level of thyroid hormone synthesis in the Camborough hybrid].

Investigations were carried out with 320 pigs of the Camborough hybrid, differentiated by sex at the age of one, two, three, and four months. The dynamic was followed up of T-3, T-4, and FT-4 in dependence on the age and sex. Some quantitative discrepancies were established in the level of these indices for both males and females and the ages under study. The physiologic parameters of thyroid hormone synthesis were determined along with the age- and sex-associated differential ranges of T-3, T-4, and FT-4.

Aging↗

[Age of menarche. Secondary sex characteristics. Interrelation. Secular trend].

Our purpose was to determine the mean age of menarche in young females of our population. To relate menarche with maturation stages of secondary sex character. To observe if the secular trend persist after the first observation. Consistently two temporal observations spaciated for 10 years were performed. Two hundred and eighty three healthy women who belonged to a higher middle-level and attending a high school from Cordoba National University were studied. Such women were in an age range between 11.0 to 18.0 years. Anthropometric and biological maturation examination were undertaken (Tanner). The mean age of onset of secondary sex characters was determined in a longitudinal follow-up group (54 girls). The mean age of menarche in the overall sample was determined by the retrospective method and in the subsample of 54 girls longitudinally followed in the 70-80 decade was determined by the prospective method in which the menarche was correlated with stages of mamary development (B) an pubic hair (PH). The mean age of menarche in 146 young females with a follow-up from 1.981 through 1.990 was determined. In the overall sample the mean of age of menarche was of 12.59 years +/- 1.17; in the subsample (54 girls) of 12.75 years +/- 1.03. In this subsample 70.37% of them has the menses in the B3 stage, 22.22% in B4, 5,5% in B2 and 1.85% in B5. 74.07% PH3, 18.51% in PH4, 0.52% in PH2 and none in PH5. In the sample of 146 young females with a follow-up between 1981 and 1990 the mean age of menarche was 12.36 years. If this result is compared with that of the 54 girls longitudinally followed in the prior decade and with the overall sample, a difference of 0.39 years and 0.23 years respectively is proved. This difference favoring an earlier age of menarche would show: 1 degree) That in our environment the secular trend is maintained, the age advances 4 months every 10 years and 2 degree) That the longitudinal prospective method is more reliable than the retrospective one.

Adolescent↗

Secondary sex characteristics of boys 12 to 17 years of age: the U.S. Health Examination Survey.

Data from the United States Health Examination Survey, Cycle III, were used to describe secondary sexual characteristics and their relationship to skeletal age in a representative sample of adolescent males aged 12 to 17 years. This survey utilized a national probability sample of youths selected to represent the U.S. population with respect to age, race, sex, geographic region, and socioeconomic status. Good concordance was found between Tanner stages for pubic hair and for genitalia. Sexual characteristics developed similarly for white and black boys, and socioeconomic status did not influence this development. Skeletal age and serum urate levels were closely related to development of pubic hair and genitalia. These data permit the physician to compare the development of individual patients with a representative sample of contemporaneous U.S. boys.

Adolescent↗

Complete development of secondary sex characteristics in a case of 46,XY pure gonadal dysgenesis.

Although pubertal development is unusual in 46,XY gonadal dysgenesis, it may occur in association with gonadal tumors. The authors report a case of 46,XY gonadal dysgenesis in a 17-year-old girl remarkable for H-Y+ phenotype and bilateral gonadoblastomas accompanied by dysgerminomatous change and nearly complete female secondary sex development. Endocrinologic activity of the gonads was indicated by marked decrease in sex steroid production after gonadectomy. Occurrence of gonadal neoplasia in this case is consistent with the observation that neoplastic transformation is likely in H-Y+ cases of 46,XY gonadal dysgenesis.

Adolescent↗