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Long term outcome after poliomyelitis in different health and social conditions.

OBJECTIVE: To examine and compare the long term outcome after polio in an east European and a west European country with different access to rehabilitation and with different medical and social conditions. DESIGN AND SETTING: The patients who were acutely hospitalised for polio 1950-54 in the University Hospital in Bergen, Norway and 1958 in the University Hospital in Tartu, Estonia received the mailed questionnaire in the period between January 1998 and December 1998. PATIENTS: Patient files concerning 334 patients hospitalised in Tartu and 243 patients hospitalised in Bergen were obtained; of these 128 Estonian and 148 Norwegian patients were re-examined. MAIN RESULTS: Despite more pronounced disability in the acute stage, significantly more Norwegian patients were working full time and part time in 1998 (p<0.0001) and also through the period 1958-1998. In both countries, 30% of patients had manual work and 18% changed profession during their career. Low income (below 50% of national average) was reported by 73% of Estonian and 35% of Norwegian patients (p<0.0001). Except for the odds ratio for muscular pain of 1.89 (95%CI =1.14 to 3.14) for Norwegian patients, new symptoms indicating late progression did not differ. Norwegian patients were more independent with significantly less need for assistance in housekeeping (p=0.02), whereas the use of orthopaedic devices did not differ. CONCLUSIONS: The long term outcome after polio is different in eastern and western Europe. Access to continuous rehabilitation seems to maintain physical independence in polio patients, improves their ability to earn their own income, and lessens the need for disability pensions.

Activities of Daily Living↗

Free choice ethanol intake of laboratory rats under different social conditions.

To study the effects of different kinds of social deprivation on voluntary ethanol (ETOH) intake male Wistar rats were housed by (a) individual caging, (b) "contact" caging (partial social deprivation), and (c) group caging (four individuals per cage). In the latter condition the individuals were separated once a week from each other for 24 h. The rats simultaneously received water 5%, 10% and 20% ETOH for a period of 14 weeks. Additional control animals received water. Isolated individuals drank significantly more alcohol than group-housed or contact-caged rats. After a few days they preferred the 20% solution. Circadian measures revealed a discontinuous intake of high doses (greater than 0.5 g/kg/h) during short time periods. Contact-caged rats consumed much less ETOH, but both the preference for 20% ETOH and the circadian course of intake were similar to those occurring after isolation. ETOH intake of group-housed individuals was low. These individuals preferred the 5% solution and continuously consumed small ETOH doses. During the period of short-term isolation they drank even more ETOH than long-term isolated individuals. In contrast to the latter, the enhancement of intake decreased after some weeks. It is suggested that the differences between the housing groups not only reflect different degrees of isolation stress, but may also be explained by a contribution of different reinforcing or aversive psychotropic effects of ETOH. Reduction of isolation stress is probably most important in the situation of short term separation, whereas dose-dependent reinforcement via social stimulation or sedation may affect the drug taking behavior under the other social conditions.

Alcohol Drinking↗

Vulvovaginal conditions: social, psychological, and sexual considerations.

Women experiencing vulvovaginal conditions are affected socially, psychologically, and sexually. Although vulvovaginitis is a common women's health problem, these considerations are overlooked in the literature and, unfortunately, often in practice, as well. This article presents a discussion of the social, psychological, and sexual issues to be considered when treating women with vulvovaginal conditions, including implications for practice.

Adaptation, Psychological↗

[The course after amputation of upper extremities with special reference to the use of prostheses and social conditions].

Sixty-six patients with upper limb amputations were followed-up in their homes. The object of this article was to assess the course as regards the prosthesis, the extent to which this was employed, and to investigate the factors which influence the type of prosthesis and the social conditions of the patient. The amputees were divided into four groups. Twenty-six employed an active prosthesis for more than eight hours daily, six for less than eight hours daily, 16 employed passive prostheses and 18 did not employ prostheses. 65% of the amputations were performed on account of accidents. A group of six were submitted to amputation as part of the treatment of irreversible brachial plexus lesion. The investigation demonstrated the significant importance of the year of amputation. This is explained by late development of the prosthesis supply and the possibilities for rehabilitation and the legislative conditions. Great differences were observed between the prosthetic conditions at the primary equipment and at follow-up investigation. The type of prosthesis employed depended on loss of the dominant arm, prostheses available and the general condition of the individual patient. There were differences in the mental reactions for patients with planned and traumatic amputations. It is recommended that this patient group should be ensured rapid fitting with prostheses by an experienced prosthesis and adequate rehabilitation within a geographically manageable district. This patient group requires team therapy and this functions best when the relevant staff are experienced with this type of patient.

Adolescent↗

Social conditions as fundamental causes of disease.

Over the last several decades, epidemiological studies have been enormously successful in identifying risk factors for major diseases. However, most of this research has focused attention on risk factors that are relatively proximal causes of disease such as diet, cholesterol level, exercise and the like. We question the emphasis on such individually-based risk factors and argue that greater attention must be paid to basic social conditions if health reform is to have its maximum effect in the time ahead. There are two reasons for this claim. First we argue that individually-based risk factors must be contextualized, by examining what puts people at risk of risks, if we are to craft effective interventions and improve the nation's health. Second, we argue that social factors such as socioeconomic status and social support are likely "fundamental causes" of disease that, because they embody access to important resources, affect multiple disease outcomes through multiple mechanisms, and consequently maintain an association with disease even when intervening mechanisms change. Without careful attention to these possibilities, we run the risk of imposing individually-based intervention strategies that are ineffective and of missing opportunities to adopt broad-based societal interventions that could produce substantial health benefits for our citizens.

Disease↗

The role of the social condition of women in the decline of maternal and female mortality.

The objective of this article is to study the changes that have occurred in the mortality pattern of women of fertile age in Spain throughout the 20th century, the significance of maternal mortality in the development of this pattern, and the other causes of death that have contributed most to such changes. Female mortality has most often been approached from the perspective of the genetic differences from males--particularly from the sexual-biological, basically reproductive, aspect--without considering other possible (social) differences. We have studied the female mortality pattern from the double incline of date of death (period) and of date of birth (cohort). Using the mortality theory of competing risks as our basis, we excluded in turn maternal mortality and mortality due to tuberculosis from overall mortality, and analyzed the transformations produced in the mortality pattern. Our results show that maternal mortality alone cannot be held responsible for the excess female mortality of the 1910s and 1920s, or for the mortality pattern among women of fertile age during the first half of this century. We suggest that the social discrimination against females from infancy has been responsible for most of the differences observed in mortality patterns.

Adolescent↗

The social conditions for nanomedicine: disruption, systems, and lock-in.

Here we consider two ways that nanomedicine might be disruptive. First, low-end disruptions that are intrinsically unpredictable but limited in scope, and second, high end disruptions that involve broader societal issues but can be anticipated, allowing opportunity for ethical reflection.

Health Care Sector↗

Photoperiod and parturition period in isolated or paired rats: influence of sight deprivation and social conditions.

Time of delivery was studied in normal (N) or enucleated (E) rats. Isolated (1/cage) at mating (day 1 of gestation), they were all anaesthetized on day 8 and some of them were then blinded. After anaesthesia, they were kept either alone (N and E) or in homogeneous (NN and EE) and heterogeneous (NE) pairs either under a 12L-12D or a 2L-22D light-dark (LD) cycle. Activity, monitored throughout the rest of pregnancy in 2 homogeneous (NN and EE) and heterogeneous (NE) pairs of rats, kept a marked circadian rhythm under each light regimen. Birth distributions differed according to LD cycle in normal (N or NN) but not in enucleated (E and EE) rats. Under the 12L-12D regimen, parturitions of N and E rats were divided into 2 parts, the majority occurred on the afternoon of day 22 before 21:00 h, the remainder were observed after 6:00 h on day 23. Under the 2L-22D regimen, N rats gave birth over one period, mainly on day 23, whereas E rats had the same birth distribution as those subjected to the 12L-12D LD cycle. In heterogeneous pairs of rats (NE), birth times were affected by photoperiod; under the 2L-22D regimen it was intermediate between those of homogeneous pairs (NN and EE). These results indicate that the eyes were the first link of the nervous chain by which photoperiod influenced birth time. Social conditions may also modulate the photodependent mechanism in ways which remain to be determined.

Animals↗

Migrant farm workers: social conditions, adaptive belief systems, and psychiatric care.

Two migrant farm labor camps were observed during two summer harvesting seasons. A part of the observations consisted of interviews with 104 farm laborers, with 16 of them being interviewed intensively. Migrant farm workers were exploited by the crew boss and the farm owner, and they in turn exploited each other. Consequently, many workers left farm work. Those who remained in the camps adapted their attitudes and their views to the conditions. Though they had a begrudging respect for the crew boss, they showed an overriding concern with exploitation. They conveyed a numbness about life, themselves, and their place in society; this numbness was combined with self criticism and an attempt to maintain some self-respect. They expressed distrust for and suspicion of others, and though they could not articulate it very well, they felt great fear and anxiety. In order to diagnose and treat disorder in migrant farm workers, psychiatrists must understand the exploitive social setting of migrant farm work and the adaptations of workers to that setting.

Adaptation, Psychological↗

Social conditions and distress in elderly persons: findings from the MacArthur Studies of Successful Aging.

The purpose of this study was to determine separate and joint associations of race/ethnicity and socioeconomic status (SES) with psychological distress among older high-functioning adults and to examine 2 psychosocial resources that may explain these associations. Participants were 70-79-year-old individuals (n = 1,189) participating in the MacArthur Studies of Successful Aging program, a 3-site study of community-dwelling men and women. Participants represented the top third of their peers in terms of functional ability in 1988. Additive and interactive models were used to examine cross-sectional associations among race/ethnicity, SES, and distress. Although decreases in distress generally occur with aging, findings suggest that social structural factors can influence distress even among elderly people. Blacks were less distressed than Whites when SES was controlled. There was a gradient between education and distress among Whites but not among Blacks. Measures of social support and control did not mediate effects of race/ethnicity on distress. These results differ from those of previous studies and indicate that age and functional status should be considered in examinations of relationships among race/ethnicity, SES, and distress.

Activities of Daily Living↗

Improving diabetic control in adverse social conditions. A home blood glucose monitoring study in Soweto, South Africa.

In order to explore the feasibility of home blood glucose monitoring (HBGM) in Type 1 diabetics in developing countries, we introduced the technique to Type 1 patients below the age of 30 yr attending the Diabetic Clinic serving Soweto in South Africa. Despite initial problems, HBGM with visually-read strips was applied to 45 of the 64 young Type 1 diabetics identified ("HBGM group"). The remaining 19 were continued on urine glucose monitoring only ("HUGM group"), usually because of attendance and compliance problems. After 4 months' follow-up, glycosylated haemoglobin (HbA1) fell from 10.5 +/- 2.6% (mean +/- SD) to 9.0 +/- 1.7 (p less than 0.001) in the HBGM group, but was unchanged (10.1 +/- 2.1 vs 9.9 +/- 1.9, pn.s.) in HUGM patients. HBGM can thus be introduced in adverse social conditions, and may be associated with improved diabetic control. Costs, in terms of finance and medical time, were not excessive. Unfortunately, a significant minority were excluded by attendance and other problems, and analysis of diabetic complication rates (before the programme began) showed that these patients had significantly more complications than those deemed suitable for HBGM (42.1% vs 15.5%, p less than 0.05).

Adult↗