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Sus scrofa domestica endoparasitic resistance in the Amazonas.

The domestic pig (Sus scrofa domestica L.) has been wild breeding in the Varzea Amazonian Estuary area. Without dietary supplement or medical prevention, the pigs survive, bringing economic benefits to local peasants. Endoparasitic diseases generate economic losses because of neonatal death and clinical disease. We assessed the nematoda (O. Nematoda) and coccidia (O. Eucoccidia) parasitic level and tolerance in 75 pigs (0-18 months) from 35 families using the following methods: (i) larvae culture, (ii) Hoffman, (iii) Willis-Mollay (Hoffman 1987) and (iv) postmortem examinations. We identified Eimeria species Strongyloidea and S. ransomi present in 60% of the cases, giving a mean of 336 and 520 EPG (eggs per gram of feces), respectively. Culturing the larvae showed S. ransomi in 47% and Oseophagostomum sp. in 17% of the cases. We found Stephanurus dentatus and Macracanthorhynchus hirudinaceus adults in 77% and 23% of the postmortem tests, respectively. Pig resistance was demonstrated by lack of mortality and no clinical disease symptoms, in the presence of that high endoparasitic load.

Animals↗

Helminthic pseudotumours of the bowel: thirty-four cases of helminthoma.

Human infestation with nematode worms of the superfamily Strongyloidea has been recorded from time to time to give rise to serious surgical complications. Worms of the genus Oesophagostomum are most frequently responsible. These are common parasites of ruminants, monkeys, and apes in which their histotropic phase is confined to the bowel wall and sometimes results in multiple inflammatory nodules. Man is an accidental host and it seems an abnormal one. The worm fails to return to the bowel lumen, migrates further and persists in the tissues. The commonest manifestation is a solitary tumour-like inflammatory mass or abscess (;helminthoma') in the ileocaecal region. The ileum, transverse and sigmoid colons are affected less commonly and the lesions are occasionally multiple. Patients may also present with abscesses of the abdominal wall. The clinical diagnosis is difficult, even at laparotomy. Carcinoma, appendicitis, ileocaecal tuberculosis are frequently simulated and unnecessary radical surgery is often the result, particularly in expatriate Europeans. In this communication 34 cases from Uganda are reviewed with emphasis on histopathology as responsibility for the correct diagnosis is likely to fall on pathologists. Three characteristic appearances are described and related to phases in the natural history of the disease. Current knowledge on parasitology is reviewed. The disease affects Africans as well as Europeans and it is anticipated that cases will be seen in those returning from the tropics.

Abdominal Muscles↗

Demonstration of shared carbohydrate epitopes in intestinal proteins of some bovine gastrointestinal nematodes.

The presence of shared carbohydrate intestinal epitopes in bovine gastrointestinal nematodes was demonstrated. Proteins were extracted from the intestinal tissue of a laboratory strain of adult Haemonchus placei and used to produce monoclonal antibodies (mAb). Analysis of this detergent extract by sodium dodecyl sulfate-polyacrylamide gel electrophoresis revealed 7-9 bands ranging from approximately 39 to 298 kDa. The mAbs reacted with periodate-sensitive epitopes and, in western blots, recognized high molecular weight protein bands (approximately 111-298 kDa). Immunohistochemical studies with the mAbs verified the intestinal location of the epitope(s) in the laboratory strain as well as in a recent field isolate of H. placei. Epitope(s) were conserved among species examined within the Trichostrongyloidea (Ostertagia ostertagi, Cooperia punctata, Haemonchus placei, and Haemonchus contortus), semiconserved among species within the Strongyloidea (present in Oesophagostomum radiatum, absent in Oesophagostomum venulosum), and absent in the only species examined in the Ancylostomatoidea (Bunostomum phlebotomum).

Animals↗