SEARCH · PubMed Health

Results for “stratification”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 73 records · Page 4Linked to original sources

PubMed2004

Hydrochemical stratification in flooded underground mines: an overlooked pitfall.

The fact that flooded underground mines are commonly hydrochemically stratified is often not appreciated. Water samples taken from the water surface in partly flooded shafts are often wrongly assumed to represent the water quality existing throughout the entire water column. In some cases, treatment systems have been designed on the basis of these often misleading water surface samples. Stratification can build up within a slowly recovering system where there are few lateral inflows and outflows to the system. Less mineralised, shallow-sourced water enters at the top of the water column and more heavily mineralised water tends to remain at the base of the water column. This water has a high dissolved solids content due to dissolution of increasing amounts of pyrite oxidation salts and other minerals as the water level rises through the old workings. However, such stratification can easily be lost following hydraulic disturbance of the system (either by pumping or by natural decant when the water level reaches an outflow pathway from the mine system, such as an old adit or shaft collar) and often results in surface discharges of poor water quality. Test pumping of one such stratified system (Frances Colliery, Scotland) has provided useful information about how stratified systems develop, and how they can behave when disturbed. The water quality observed after stratification was disturbed by pumping was worse than would have been anticipated on the basis of water samples taken from the surface of the water column prior to pumping (with concentrations of contaminants such as iron and zinc being around two orders of magnitude greater than in water surface samples). Taken together with other information from the literature, the experience at Frances Colliery supports the proposal of criteria for recognising when stratification of mine water quality might be anticipated, thus facilitating the timely deployment of measures required for its detection at an early stage.

Disasters↗

PubMed2003

Practical applications in stress echocardiography: risk stratification and prognosis in patients with known or suspected ischemic heart disease.

OBJECTIVES: The purpose of this study was to define appropriate parameters for risk stratification and prognosis in patients undergoing stress echocardiography. BACKGROUND: Stress echocardiography is an established technique for the diagnosis of coronary artery disease. However, current data on risk stratification of patients undergoing stress echocardiography are limited. METHODS: We evaluated 1,500 patients (59 +/- 13 years old; 51% male) undergoing stress echocardiography (34% with treadmill exercise and 66% with dobutamine). Resting left ventricular ejection fraction (EF) and regional wall motion were assessed by the consensus of two echocardiographers. Follow-up (mean 2.7 +/- 1.0 years) for confirmed non-fatal myocardial infarction (n = 31) and cardiac death (n = 44) were performed. RESULTS: By univariate analysis, both the peak wall motion score index (WMSI) (p < 0.0001) and EF (p < 0.0001) were significant predictors of cardiac events. Peak WMSI effectively risk stratified patients into low (0.9%/year), intermediate (3.1%/year), and high (5.2%/year) risk groups (p < 0.0001). A threshold of 45% EF provided further risk stratification of all WMSI groups. By multivariate logistic regression analysis, peak WMSI (relative risk [RR] 2.1, 95% confidence interval [CI] 1.0 to 4.4; p = 0.04) and EF (RR 1.0, 95% CI 0.9 to 1.0; p = 0.01) were both predictors of cardiac events. CONCLUSIONS: Stress echocardiography yields prognostic information for risk stratification of patients with known or suspected ischemic heart disease. A normal stress echocardiographic study (peak WMSI = 1.0) confers a benign prognosis (0.9%/year cardiac event rate). Peak WMSI >1.7 and EF < or =45% are independent markers of patients at high risk of an adverse clinical outcome.

Echocardiography, Stress↗

PubMed2003

Prevalence of left ventricular hypertrophy in patients with mild hypertension in primary care: impact of echocardiography on cardiovascular risk stratification.

BACKGROUND: Left ventricular hypertrophy (LVH) is an important predictor of cardiovascular risk, and its detection contributes to risk stratification. The aims of the present study were to estimate the prevalence of echocardiographic LVH and to evaluate the influence of echocardiography (ECHO) on cardiovascular risk stratification in hypertensive patients presenting in primary care. METHODS: In this cross-sectional study, 250 patients recently diagnosed with mild hypertension underwent clinical evaluation including electrocardiography (ECG), microalbuminuria measurement, 24-h blood pressure monitoring and ECHO. Level of cardiovascular risk was stratified, initially using routine procedures including ECG to assess target organ damage and then again after detection of LVH by ECHO. RESULTS: The frequency of echocardiographic LVH was 32%, substantially higher than that detected by ECG (9%). Initial cardiovascular risk stratification yielded the following results: 30% low risk, 49% medium risk, 16% high risk, and 5% very high risk subjects. The detection of LVH by ECHO provoked a significant change in the risk strata distribution, particularly in those patients initially classified as being at medium risk. In this group, 40% of subjects were reclassified as high risk subjects according to ECHO information. The new classification was as follows: 23% low risk, 30% medium risk, 42% high risk, and 5% very high risk subjects. CONCLUSIONS: A substantial proportion of mildly hypertensive patients presenting in primary care have LVH determined by ECHO. Our results suggest that this procedure could significantly improve cardiovascular risk stratification in those patients with multiple risk factors, but no evidence of target organ damage by routine investigations.

Albuminuria↗

PubMedDate not supplied

Organization of the inner retina following early elimination of the retinal ganglion cell population: effects on cell numbers and stratification patterns.

The present study has examined the effects of early ganglion cell elimination upon the organization of the inner retina in the ferret. The population of retinal ganglion cells was removed by optic nerve transection on the second postnatal day, and retinas were subsequently studied in adulthood. Numbers of amacrine and bipolar cells were compared in the nerve-transected and nerve-intact retinas of operated ferrets, while stratification patterns within the inner plexiform layer were compared in these and in normal ferret retinas. Early ganglion cell elimination was found to produce a 25% reduction in the population of glycine transporter-immunoreactive amacrine cells, and 18 and 15% reductions in the populations of parvalbumin and calbindin-immunoreactive amacrine cells, respectively. GABAergic amacrine cells were also reduced by 34%. The number of calbindin-immunoreactive displaced amacrine cells, by contrast, had increased in the ganglion cell-depleted retina, being three times their normal number. Other amacrine and bipolar cell types were unaffected. Despite these changes, the stratification patterns associated with these cell types remained largely intact within the inner plexiform layer. The present results demonstrate a class-specific dependency of inner retinal neurons upon the ganglion cell population in early postnatal life, but the ganglion cells do not appear to provide any critical signals for stratification within the inner plexiform layer, at least not after birth. Since they themselves do not produce stratified dendritic arbors until well after birth, the signals for stratification of the bipolar and amacrine cell processes should arise from other sources.

Amino Acid Transport Systems, Neutral↗

PubMed2004

Polar ocean stratification in a cold climate.

The low-latitude ocean is strongly stratified by the warmth of its surface water. As a result, the great volume of the deep ocean has easiest access to the atmosphere through the polar surface ocean. In the modern polar ocean during the winter, the vertical distribution of temperature promotes overturning, with colder water over warmer, while the salinity distribution typically promotes stratification, with fresher water over saltier. However, the sensitivity of seawater density to temperature is reduced as temperature approaches the freezing point, with potential consequences for global ocean circulation under cold climates. Here we present deep-sea records of biogenic opal accumulation and sedimentary nitrogen isotopic composition from the Subarctic North Pacific Ocean and the Southern Ocean. These records indicate that vertical stratification increased in both northern and southern high latitudes 2.7 million years ago, when Northern Hemisphere glaciation intensified in association with global cooling during the late Pliocene epoch. We propose that the cooling caused this increased stratification by weakening the role of temperature in polar ocean density structure so as to reduce its opposition to the stratifying effect of the vertical salinity distribution. The shift towards stratification in the polar ocean 2.7 million years ago may have increased the quantity of carbon dioxide trapped in the abyss, amplifying the global cooling.

Animals↗

PubMed2001

Influence of different echocardiographic criteria for detection of left ventricular hypertrophy on cardiovascular risk stratification in recently diagnosed essential hypertensives.

BACKGROUND: Hypertensive patients with left ventricular hypertrophy (LVH) need a prompter and more intensive pharmacological treatment than subjects without evidence of cardiac involvement. So the detection of LVH plays an important role for decision-making in hypertensives. OBJECTIVE: To evaluate the impact of different echocardiographic criteria to define LVH in a more precise stratification of absolute cardiovascular risk in hypertensives without target organ damage (TOD) as assessed by routine investigations. METHODS: A total of 100 never treated patients with grade 1 and 2 essential hypertension (53 men, 47 women, age 44 +/- 12 years) referred for the first time to our outpatient clinic were included in the study. They underwent the following procedures: (1) family and personal medical history, (2) clinic blood pressure (BP) measurement, (3) routine blood chemistry and urine analysis, (4) electrocardiogram, (5) echocardiogram. Risk was stratified according to the criteria suggested by the 1999 WHO-ISH guidelines. TOD was initially evaluated by routine procedures only, and subsequently reassessed by using six different echocardiographic criteria to recognise LVH: (a) left ventricular mass index (LVMI) >120 g/m(2) in men and 100 g/m(2) in women; (b) 125 g/m(2) in men and 110 g/m(2) in women; (c) 134 g/m(2) in men and 110 g/m(2) in women; (d) 125 g/m(2) in men and 125 g/m(2) in women; (e) 51 g/m(2.7) in men and 47 g/m(2.7) in women; (f) 126 g/m in men and 105 g/m in women. RESULTS: According to the first classification based on routine investigations, 46% were low risk and 54% were medium risk patients. Significant changes in risk stratification were obtained when LVH was assessed by echocardiography. A percentage of patients, ranging from 9 (f) to 25% (d), were found to having LVH according to different criteria, and consequently moved from low and medium risk strata to high risk stratum. CONCLUSIONS: The detection of LVH by echocardiography allowed a much more accurate identification of high risk patients. In particular our results suggest that: (1) cardiovascular risk stratification only based on a simple routine work-up can often underestimate overall risk; (2) a better standardisation in defining LVH is needed, considering that the impact of cardiac hypertrophy on risk stratification is markedly dependent on the echocardiographic criteria used to diagnose it.

Adult↗

PubMed2003

Risk stratification and management of sudden cardiac death: a new paradigm.

Risk Stratification and Management of SCD. Management of SCD is undergoing radical change in direction. It is becoming increasingly appreciated that besides depressed left ventricular systolic function and the conventional risk stratification tools, new markers for plaque vulnerability, enhanced thrombogenesis, specific genetic alterations of the autonomic nervous system, cardiac sarcolemmal and contractile proteins, and familial clustering may better segregate patients with atherosclerotic coronary artery disease who are at high risk for SCD from those who may suffer from nonfatal ischemic events. Better understanding of pathophysiologic processes, such as postmyocardial infarction remodeling, the transition from compensated hypertrophy to heart failure, and the increased cardiovascular risk of coronary artery disease in the presence of diabetes or even a prediabetic state will help to improve both risk stratification and management. The rapidly developing fields of microchips technology and proteomics may allow rapid and cost-effective mass screening of multiple risk factors for SCD. The ultimate goal is to identify novel methods for risk stratification, risk modification, and prevention of SCD that could be applied to the general public at large.

Coronary Artery Disease↗

PubMed2003

Usefulness of risk stratification for future cardiac events in infarct survivors with severely depressed versus near-normal left ventricular function: results from a prospective long-term follow-up study.

BACKGROUND: Although primary preventive therapy with implantable cardioverter defibrillators has recently been shown to be effective in patients with coronary artery disease and left ventricular dysfunction, further identification of patients at particularly high risk for arrhythmic death would improve the cost effectiveness of device therapy. The value of risk stratification in postinfarction patients with versus those without left ventricular dysfunction has not been investigated in detail in infarct survivors treated according to contemporary therapeutic guidelines. METHODS: Patients with acute myocardial infarction underwent coronary angiography including left ventricular angiography in an attempt to restore antegrade flow of the infarct-related artery. Additionally, patients underwent noninvasive autonomic risk stratification by means of heart rate variability (HRV) and baroreflex sensitivity (BRS) measurements prior to hospital discharge. RESULTS: A total of 411 patients were prospectively included in the study. The primary study endpoint of cardiac death and arrhythmic events was significantly more common in patients with LVEF < or = 35% as compared to those with preserved LV function (27% vs 4%; P < 0.0001). In patients with LV dysfunction, HRV and BRS were significant risk predictors on univariate (P < 0.01 for BRS; P = 0.04 for HRV) and multivariate (P = 0.028 for BRS; P = 0.053 for HRV) analyses. In contrast, in patients with preserved LV function, only patency of the infarct artery but not autonomic markers was significantly predictive of cardiac death and arrhythmic events. CONCLUSION: The present study demonstrates that autonomic testing does not yield predictive power in infarct survivors with preserved left ventricular function. Accordingly, cost effectiveness of risk stratification and subsequent preventive therapy may be improved by restricting risk stratification to patients with impaired LV function.

Aged↗

PubMed1999

Does the new TNM classification (1997) improve prognostic stratification in gastric cancer submitted to R0 surgery?

AIMS: To determine the eventual advantage of the new 1997 TNM as prognosis predictor for gastric cancer patients submitted to an R0 resection and to compare it with two other lymph-node involvement classifications, the 1990 TNM and the Okusa system. METHODS: From January 1980 to December 1995, an R0 resection was performed as primary therapy in 275 cases of gastric cancer. These operations consisted of a total or sub-total gastrectomy and of a D2 type lymph-node dissection. Tumour classification was performed according to 1990 and 1997 TNM systems, and to the Okusa lymph node classification. The statistical methods used to evaluate prognostic value were: Kaplan-Meier survival estimates; the log-rank test for univariate analysis; and Cox's model for multivariate analysis. RESULTS: The 1990 TNM showed the best stratification power in univariate analysis. In multivariate analysis, the Okusa classification was identified as the best prognostic index (P<0.01). The 1997 TNM showed worse stratification capability than the two other systems. CONCLUSIONS: In the present series, the new TNM (1997) did not improve the prognostic stratification of lymph-node involvement. An adequate and universal system for lymph-node stratification is necessary and further validation of these classifications is needed.

Aged↗

PubMed1984

The effects of illumination level and retinal size on the depth stratification of subjective contour figures.

The apparent stratification in depth of subjective contour figures over their backgrounds was investigated as a function of illumination level, figure size, and viewing distance. Magnitude estimation, with a real contour figure serving as the modulus, was used to measure the stratification in depth of a subjective contour figure over its background. Illumination level and retinal size both had significant effects on the depth stratification of the subjective contour figures. The greatest apparent depth differences were obtained for figures of small retinal size under low levels of illumination. These results paralleled previous findings for judgments of subjective contour strength. Consequently, both contour clarity and depth stratification of subjective contour figures are affected in similar ways by illumination level, figure size, and viewing distance. The implications of this response coupling are discussed in terms of current theories of subjective contours.

Adult↗

PubMed2001

The material and the symbolic in theorizing social stratification: issues of gender, ethnicity and class.

Within most approaches to stratification gender and ethnicity are seen to pertain primarily to the symbolic or cultural realms, whilst class is regarded as pertaining to material inequality. This constructs gender and ethnic positioning as entailing honour, deference, worth, value and differential treatment (sometimes expressed through the notion of 'status'), but the social relations around these are themselves not seen as constitutive of social stratification. In this paper I will rethink social stratification away from the polarity between the material and the symbolic, and argue that material inequality, as a set of outcomes relating to life conditions, life chances and solidary processes, is informed by claims and struggles over resources of different types, undertaken in terms of gender, ethnicity/race and class. This formulation allows us to include these categorial formations, alongside class, as important elements of social stratification i.e. as determining the allocation of socially valued resources and social places/locations.

Ethnicity↗

PubMed2004

Cardiovascular risk stratification according to the 2003 ESH-ESC guidelines in uncomplicated patients with essential hypertension: comparison with the 1999 WHO/ISH guidelines criteria.

BACKGROUND: The 2003 European Society of Hypertension/European Society of Cardiology (ESH-ESC) guidelines have recently proposed a new risk stratification scheme for estimating absolute risk for cardiovascular disease. At variance from the previous 1999 World Health Organization-International Society of Hypertension (WHO/ISH) guidelines, the new criteria include some additional risk factors such as obesity, abnormal high-density (HDL) or low-density lipoprotein (LDL) cholesterol levels and define a slight increase in creatinine and microalbuminuria as signs of target organ damage (TOD). OBJECTIVE: The aim of the study was to assess overall cardiovascular risk in uncomplicated hypertensives according to the 2003 ESH-ESC guidelines comparing this approach with the stratification scheme of the 1999 WHO/ISH guidelines. METHODS: Four hundred and twenty-five never-treated grade 1 and 2 essential hypertensive patients, referred for the first time to our outpatient clinic without diabetes mellitus, were included in the study. They underwent the following procedures: (i) repeated clinical blood pressure measurements; (ii) routine blood chemistry and urine analysis; (iii) electrocardiogram; (iv) 24-h urine collection for microalbuminuria; (v) echocardiogram; and (vi) carotid ultrasonogram. Risk was assessed according to both stratification schemes suggested by the 2003 ESH-ESC and 1999 WHO/ISH guidelines. RESULTS: According to the 2003 ESH-ESC guidelines, 15.5% of the 425 patients were considered at low added risk, 47.8% at medium added risk and 36.7% at high added risk; 146 patients (34.3%) were classified in the high-risk stratum because of at least one manifestation of TOD and 5.6% having three or more risk factors. The accuracy in detecting TOD of the combined approach with ultrasound procedures and microalbuminuria was approximately 10-fold higher than that provided by routine investigation. As a result of the 1999 WHO/ISH stratification scheme, 34.5% were low-risk, 34.4% medium-risk and 31.1% high-risk patients. CONCLUSIONS: Our findings show that: (i) more than one-third of uncomplicated grade 1 and 2 hypertensives seen in a outpatient hypertension hospital clinic have a high added risk according to the ESH-ESC scheme; (ii) classification of the patients in the high stratum is mainly influenced by the presence of TOD; (iii) the routine diagnostic work-up is a highly insensitive approach for the detection of TOD; (iv) the 2003 ESH-ESC guidelines stratify a higher proportion of hypertensive patients in the medium and high-risk groups than do the 1999 WHO/ISH guidelines.

Adult↗

PubMedDate not supplied

Gender and cultural differences in the association between family roles, social stratification, and alcohol use: a European cross-cultural analysis.

AIMS: First, this paper investigates (i) gender differences in associations of social stratification, family roles, and heavy drinking, and (ii) country differences in these associations. Second, it seeks to explain country differences in the associations of social stratification and family roles with alcohol consumption by societal level variables. METHODS: Survey data of 25 to 49-years-old from eight European countries were used. Logistic regressions were used to analyse gender differences in the association between family roles (marriage, having children), social stratification (education, employment), and heavy drinking (>20 g/day for women; 30 g/day for men). Gender differences were tested by means of interactions between gender and social stratification/family roles. Structural measures of work desirability, social welfare, and gender equity were used to explain differences in associations across countries. RESULTS: The associations between social stratification, family roles, and heavy drinking varied across gender and countries. A country's social welfare system was associated with heavy drinking only among women. Women in countries with a strong social welfare system, such as Nordic countries, tended to drink more heavily if employed, having lower formal education, and a non-traditional family role. In countries with weak social welfare systems or work desirability, heavy drinking was associated with high education, while effects of family roles and employment were small. CONCLUSIONS: It appeared that the social welfare system and gender equity of a country determines to a large extent how education, employment, and family roles are associated with heavy drinking.

Adult↗

PubMed1983

A reconceptualization of age stratification in China.

Using the concepts of age stratification theory--age effect, cohort effect, and subcohort differences--this paper provides a new perspective on age stratification in China. Currently, the literature suggests that the status of elderly people declined after the Communist Revolution and will further decline with modernization. We discuss the problems with this perspective and argue, instead, that the status of elderly adults did not decline for the majority of the aged during the Maoist years. Rather, the most important change in the age stratification system during the Maoist years was the change in the criterion of age stratification--from age differences to cohort and subcohort differences. Furthermore, the subcohort of elderly adults who suffered the most status decline during the Maoist years--the bourgeoisie--may actually enjoy an increase in status with the recent modernization impetus. Research suggestions from this new perspective are discussed.

Adolescent↗

PubMed2003

The associations of social class and social stratification with patterns of general and mental health in a Spanish population.

BACKGROUND: Social class, as a theoretical framework, represents a complementary approach to social stratification by introducing social relations of ownership and control over productive assets to the analysis of inequalities in economic, political, and cultural resources. In this study we examined whether measures of social class were able to explain and predict self-reported general and mental health over and above measures of social stratification. METHODS: We tested this using the Barcelona Health Interview Survey, a cross-sectional survey of 10 000 residents of the city's non-institutionalized population in 2000. We used Erik Olin Wright's indicators of social class position, based on ownership and control over productive assets. As measures of social stratification we used the Spanish version of the British Registrar General (BRG) classification, and education. Health-related variables included self-perceived health and mental health as measured by Goldberg's questionnaire. RESULTS: Among men, high level managers and supervisors reported better health than all other classes, including small business owners. Low-level supervisors reported worse mental health than high-level managers and non-managerial workers, giving support to Wright's contradictory class location hypothesis with regard to mental health. Social class indicators were less useful correlates of health and mental health among women. CONCLUSIONS: Our findings highlight the potential health consequences of social class positions defined by power relations within the labour process. They also confirm that social class taps into parts of the social variation in health that are not captured by conventional measures of social stratification and education.

Adolescent↗

PubMed2006

Risk stratification in acute coronary syndromes--does the TIMI risk score work in unselected cases?

BACKGROUND: Management of patients with an acute coronary syndrome (ACS) requires accurate risk stratification to guide appropriate therapy. AIM: To assess the utility of the TIMI risk score in stratifying patients with possible ACS in routine clinical practice. DESIGN: Prospective observational study. METHODS: We recruited 869 consecutive patients with a diagnosis of possible ACS attending the acute medical receiving unit of a district general hospital. The main outcome measures were recurrent myocardial infarction, urgent revascularization, and all-cause mortality. TIMI risk score was calculated for each patient, and each was also assigned a risk group based on electrocardiogram (ECG) changes and troponin levels only. After follow-up, Cox univariate and multivariate regression was used to evaluate the influence of potential risk factors on duration of event-free survival, and likelihood ratio tests to assess the fit of the models. RESULTS: Increasing TIMI risk score was associated with increased risk of events (p<0.001), as was higher risk group from ECG plus troponin stratification (p<0.001). The likelihood ratio comparison favoured the TIMI risk score (difference 13.910, 5 degrees of freedom, p = 0.016). DISCUSSION: The TIMI risk score is a valid tool for risk stratification in unselected cases with possible acute coronary syndrome. It is superior to ECG changes and troponin alone, although this simpler method also achieves good risk stratification.

Adolescent↗

PubMedDate not supplied

Risk stratification for exercise training in cardiac patients: do the proposed guidelines work?

PURPOSE: Four authoritative organizations (American Association of Cardiovascular and Pulmonary Rehabilitation [AACVPR], the American College of Cardiology [ACC], the American College of Physicians [ACP], and the American Heart Association [AHA]) have risk stratification guidelines for supervised exercise in patients with cardiovascular disease. The ability of the guidelines to predict exercise complications is untested. METHODS: A prospective sample was evaluated that included 239 patients enrolled for a total of 5720 patient exercise hours in a phase II supervised outpatient cardiac rehabilitation exercise program between December 1, 1992, and June 16, 1995, who had had preprogram stress testing and/or left ventricular ejection fraction determination. Complications during supervised exercise were measured. RESULTS: Overall, 12 patients experienced complications during supervised exercise. None of the guidelines was predictive of complications (positive predictive values, 3-7%). Regression analyses demonstrated that current cigarette smoking was the only predictor of complications. There was reasonable correlation of patient risk stratification among the four guidelines (r = 0.19-0.47; P < 0.0001). CONCLUSIONS: Currently proposed exercise risk stratification guidelines are not predictive of complications during supervised exercise. Further work is needed before exercise risk stratification guidelines are used to adjudicate use of supervised services.

Aged↗

PubMed2004

Evaluation of stratification factors and score-scales in clinical trials of treatment of clinical mastitis in dairy cows.

There is often a need to reduce sample size in clinical trials due to practical limitations and ethical considerations. Better comparability between treatment groups by use of stratification in the design, and use of continuous outcome variables in the evaluation of treatment results, are two methods that can be used in order to achieve this. In this paper the choice of stratification factors in trials of clinical mastitis in dairy cows is investigated, and two score-scales for evaluation of clinical mastitis are introduced. The outcome in 57 dairy cows suffering from clinical mastitis and included in a clinical trial comparing homeopathic treatment, placebo and a standard antibiotic treatment is investigated. The strata of various stratification factors are compared across treatments to determine which other factors influence outcome. The two score scales, measuring acute and chronic mastitis symptoms, respectively, are evaluated on their ability to differentiate between patients classified from clinical criteria as responders or non-responders to treatment. Differences were found between the strata of the factors severity of mastitis, lactation number, previous mastitis this lactation and bacteriological findings. These factors influence outcome of treatment and appear relevant as stratification factors in mastitis trials. Both score scales differentiated between responders and non-responders to treatment and were found useful for evaluation of mastitis and mastitis treatment.

Animals↗