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At least 721 records · Page 40Linked to original sources
PubMed1997

Trail Making Test in assessing children with reading disabilities: a test of executive functions or content information.

The speed of performance on Part A, Part B, and on an experimental version containing alphabetical series (Part A Alphabetic) of the Trail Making Test was studied with 19 children with reading disabilities and 34 controls from Grades 4 to 6. When the test was used in discriminant profile fashion, children with reading disabilities showed a deficit compared with control children on Part B relative to part A but did not relative to the new Part A Alphabetic. The results indicate that the performance of the children with reading disabilities on Part B is likely to be affected by their slowness on the alphabetical series. Based on these results we recommend that the speed of following the alphabetical series be assessed when using Part B of the Trail Making Test.

Child↗
PubMed2003

Personality and executive functioning as risk factors in recidivists.

The classification of an inmate population at a maximum security jail in Canada was undertaken to study factors correlated with recidivism. A total of 12 recidivists and 12 nonrecidivists were classified according to their index offenses, and a Criminal Record search was completed to verify their statements. A total of 15 non-offenders who had also undergone a criminal record check were included as controls. All participants were administered the Minnesota Multiphasic Personality Inventory-168, Violence Risk Scale-Experimental Version, Coopersmith Self-esteem Inventory, and the Wisconsin Card Sorting Task. Statistical analysis showed significant differences between the groups on scores for the Hypochondriasis, Psychopathic Deviate, and Hypomania scales of the MMPI-168. Significant differences were noted for the Wisconsin Card Sorting Task and the Violence Risk Scale. Discriminant analysis of the recidivists and nonrecidivists correctly classified at a 91.3% level.

Adult↗
PubMed2003

Prescription of amiodarone through a computerized template that includes both decision support and executive functions improves the monitoring for toxicities.

The antiarrhythmic drug amiodarone causes severe side effects that warrant active monitoring. In a given patient, monitoring for amiodarone toxicities involves checking past results of five laboratory/imaging tests and reordering four of these tests every 6 to 12 month, a process that is both complex and time-consuming. We hypothesized that a software tool that automated the retrieval and ordering of these tests in a context-sensitive manner would improve the completeness of surveillance for drug toxicities.

Amiodarone↗
PubMedDate not supplied

[Intraoperative assessment of cognitive and executive functions in patients with brain tumors].

BACKGROUND AND PURPOSE: The aim of this paper was to evaluate the usefulness of selected methods of intraoperative neuropsychological assessment. In order to investigate the influence of the direct cortical stimulation and tumor resection on the patients' intraoperative performance, we examined selected areas of cerebral cortex involved in cognitive activity in patients undergoing awake craniotomy for brain tumors. MATERIAL AND METHODS: The analyzed group consisted of 21 patients (11 men, 10 women) with tumors located in eloquent areas of the left hemisphere. All patients had intact understanding of speech and relatively minor neurological deficits. We applied both experimental methods as well as certain standardized tests (WAIS-R, AVLT) for the investigation of verbal and nonverbal functions. The tests were performed during direct cortical stimulation and tumor resection, and also before and one week after the operation. RESULTS: Verbal areas were identified in 10 patients, sensorimotor strip in 3, whereas both of them in 3. Even though in 5 out of 21 subjects we were unable to identify the eloquent cortex, there was no difference between pre- and postoperative assessment in these patients. Similarly, there was no statistically significant difference in pre- and postoperative tests among patients with successful cortical mapping. CONCLUSIONS: We showed that the presented methods of intraoperative assessment of cognitive activity were useful and appropriate for the identification of the eloquent areas of the brain.

Adolescent↗
PubMedDate not supplied

Flexible adaptation to changing task demands in severe closed head injury patients: a driving simulator study.

The assessment of fitness to drive in patients with closed head injury (CHI) does not usually include executive functioning. Executive functions may be particularly important for the tactical (e.g. anticipatory adaptation of speed) and strategical (e.g. choice of route and time) aspects of driving. The literature lacks evidence on the tactical aspects, which are critical in the assessment of actual driving. Executive functioning was therefore assessed in a task context relevant to tactical decision making in driving. Twenty very severe chronic CHI patients and 20 healthy control subjects were tested with a driving simulator test and an extended neuropsychological test battery. In the driving simulator test, executive function was operationally defined as the flexible adaptation to changing task demands. A specific feature of the test was the experimental control for slow information processing, a persistent sequel of severe CHI. Given this control for slow information processing, it was found that patients were unimpaired in their flexible adaptations. Similar findings were obtained with a neuropsychological test battery. Patients were consistently slower, but planning and flexibility were found to be unimpaired.

Journal Article↗
PubMed2002

Cognitive deficits among methamphetamine users with attention deficit hyperactivity disorder symptomatology.

Understanding the association between attention deficit hyperactivity disorder (ADHD) and substance abuse, specifically methamphetamine (MA) abuse, is challenging, partly because little is known about the specific constellation of cognitive impairments produced by MA. The present investigation serves to address this relationship by comparing the cognitive performance of MA abusers with ADHD symptomatology (n = 28) and MA abusers without ADHD symptomatology (n = 41) on tests of attention, memory and general intellectual functioning, executive functioning, problem solving, verbal fluency, and abstract thinking. Both MA samples had deficiencies in measures of memory and learning function, psychomotor speed and abstract thinking when compared to a control group (n = 40). Additional deficits were noted on tasks involving executive functioning, attention, and general intellectual functioning in MA abusers with ADHD symptomatology. The preliminary data suggests that executive function deficits and some of the symptoms associated with long-term MA use may be due to the fact that a large proportion of MA addicts had ADHD symptomatology as children.

Adult↗