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Verbal self-regulation over time in preschool children at risk for attention and behavior problems.

This study is a prospective, longitudinal attempt to explore behavioral self-regulation, private speech, and speech-action coordination in a sample of behaviorally at-risk preschool children. Preschoolers (N = 72) were classified at age 3 years into a behaviorally at-risk group or a comparison group on the basis of preschool teacher behavioral ratings. Children were videotaped on four different occasions across the span of almost 2 years as they completed problem-solving tasks, and private speech, task performance, executive functioning, and speech-action coordination were analyzed. Children identified 2 years earlier as being hard to manage were at risk for continued behavior problems at elementary school entry. Behaviorally at-risk children consistently used more spontaneous private speech than comparison children across all observations. Both groups of children demonstrated a pattern of increasing silence with task success over time. No group differences were observed in children's speech-action coordination at age 5 years. Intraindividual developmental changes in private speech for both groups were associated with task performance, speech-action coordination, and executive functioning at age 5, but not with teacher- and parent-reported problem behavior.

Attention↗

Biofeedback, cognitive training and relaxation techniques as multimodal adjunct therapy for hospitalized adolescents: a pilot study.

Modifications and adjuncts to traditional therapy techniques appear to be necessary for successfully treating hospitalized adolescents with impaired social and verbal skills, and a history of acting-out behavior. Modified therapy groups were combined with a structured biofeedback and cognitive training program to help these adolescents control anger and modify their behavior. Used in conjunction with training and practice in relaxation techniques, this multimodal treatment approach appeared to be helpful in both reducing incidents of acting out on residential units, and in reaching individualized therapeutic goals. The present paper describes use of this multimodal approach within selected residential settings, and outlines the structured materials developed by the authors.

Acting Out↗

Is violent method of suicide a behavioral marker of lifetime aggression?

OBJECTIVE: The main purpose of this study was to investigate whether the method of suicide is a valid behavioral marker of a lifetime history of aggression. METHOD: The authors applied the psychological autopsy method to investigate 310 individuals who committed suicide. They used structured clinical assessments and personality trait scales in interviews with family members of the deceased. RESULTS: Violent method was associated with a higher level of lifetime aggression and a higher level of impulsivity. In addition, violent method was associated with lifetime substance abuse or dependence and psychotic disorders. Controlling for age, sex, substance disorders, and other major psychopathology, the authors found that lifetime aggression and the interaction between impulsivity and aggressive behavior remained associated with violent method. CONCLUSIONS: These results support the use of violent method of suicide as a behavioral marker of a higher level of lifetime impulsive-aggressive behaviors.

Adult↗

The measurement of suicidality, aggressivity and impulsivity.

1. From an evolutionary point of view aggressive behavior increases the chances of individual survival as well as inclusive fitness. 2. There are brain structures and biochemical systems that are involved in the regulation of aggressive behavior. 3. Genetic studies have revealed genetic contributions to aggressive as well as impulsive behaviors. 4. Research has demonstrated correlations between measures of suicidality, violence and impulsivity. 5. A two-step model of countervailing forces has been developed that identifies amplifiers and attenuators of the aggressive impulse. This model has enabled us to determine a set of variables that influence suicide but not violence and another set that influences violence but not suicide.

Aggression↗

The control of deliberate waiting strategies in a stop-signal task.

To inhibit an ongoing flow of thoughts or actions has been largely considered to be a crucial executive function, and the stop-signal paradigm makes inhibitory control measurable. Stop-signal tasks usually combine two concurrent tasks, i.e., manual responses to a primary task (go-task) are occasionally countermanded by a stimulus which signals participants to inhibit their response in that trial (stop-task). Participants are always instructed not to wait for the stop-signal, since waiting strategies cause the response times to be unstable, invalidating the data. The aim of the present study was to experimentally control the strategies of waiting deliberately for the stop-signal in a stop-task by means of an algorithm that measured the variation in the reaction times to go-stimuli on-line, and displayed a warning legend urging participants to be faster when their reaction times were more than two standard deviations of the mean. Thirty-four university students performed a stop-task with go- and stop-stimuli, both of which were delivered in the visual modality and were lateralized within the visual field. The participants were divided into two groups (group A, without the algorithm, vs group B, with the algorithm). Group B exhibited lower variability of reaction times to go-stimuli, whereas no significant between-group differences were found in any of the measures of inhibitory control, showing that the algorithm succeeded in controlling the deliberate waiting strategies. Differences between deliberate and unintentional waiting strategies, and anxiety as a probable factor responsible for individual differences in deliberate waiting behavior, are discussed.

Adolescent↗

Impulsivity and the self-defeating behavior of narcissists.

Currently prominent models of narcissism (e.g., Morf and Rhodewalt, 2001) primarily explain narcissists' self-defeating behaviors in terms of conscious cognitive and affective processes. We propose that the disposition of impulsivity may also play an important role. We offer 2 forms of evidence. First, we present a meta-analysis demonstrating a strong positive relationship between narcissism and impulsivity. Second, we review and reinterpret the literature on 3 hallmarks of narcissism: self-enhancement, aggression, and negative long-term outcomes. Our reinterpretation argues that impulsivity provides a more parsimonious explanation for at least some of narcissists' self-defeating behavior than do existing models. These 2 sources of evidence suggest that narcissists' quest for the status and recognition they so intensely desire is thwarted, in part, by their lack of the self-control necessary to achieve those goals.

Affect↗

Is prenatal smoking associated with a developmental pattern of conduct problems in young boys?

OBJECTIVE: Prenatal smoking is robustly associated with increased risk of conduct problems in offspring. Observational studies that provide detailed phenotypic description are critical for generating testable hypotheses about underlying processes through which the effects of prenatal smoking may operate. To this end, we use a developmental framework to examine the association of exposure with (1) oppositional defiant disorder and attention-deficit/hyperactivity disorder in young boys and (2) the pattern of delinquent behavior at adolescence. METHOD: Using diagnostic measures and repeated measures of delinquency, we compare exposed and nonexposed boys from the youngest cohort of the Pittsburgh Youth Study (N = 448). RESULTS: Exposed boys were significantly more likely to (1) develop oppositional defiant disorder and comorbid oppositional defiant disorder-attention-deficit/hyperactivity disorder but not attention-deficit/hyperactivity disorder alone and (2) to have an earlier onset of significant delinquent behavior. CONCLUSIONS: The early emergence and developmental coherence of exposure-related conduct problems is striking and is consistent with a behavioral teratological model. Phenotypically, exposure-related conduct problems appear to be characterized by socially resistant and impulsively aggressive behavior. Whether prenatal smoking plays an etiological role in or is a risk marker for the development of conduct problems, exposed offspring are at increased risk of an early-starter pathway to conduct problems.

Adolescent↗

Childhood antecedents of schizophrenia: developmental sequencing and specificity of problem behavior.

Childhood antecedents of schizophrenia were explored for 148 boys seen in child guidance clinics prior to the onset of adolescent or adult disorders. Those most disturbed in childhood were more likely to be preschizophrenic, and their disturbed behavior was relatively specific to that grouping. Childhood problems with motor coordination and attention were associated with impulsive, inappropriate behavior which led to peer rejection followed by increasing seclusiveness. Clinical grouping of the most disturbed boys produced composite descriptions for four groups.

Adolescent↗

Lack of association between the functional variant of the catechol-o-methyltransferase (COMT) gene and early-onset alcoholism associated with severe antisocial behavior.

Addictive drugs, including ethanol, increase the brain's dopaminergic transmission, and catechol-o-methyltransferase (COMT) enzyme has a crucial role in dopamine inactivation. A common functional polymorphism in the COMT gene results in a three- to four-fold variation in enzyme activity. In a previous study, we found an association between type 1 (with late-onset but without prominent antisocial behavior) alcoholism and the low activity allele of the COMT gene. In this work we analyzed whether the COMT polymorphism has any effect on the development of type 2 (with early-onset and habitual impulsive violent behavior) alcoholism. The COMT genotype was determined in 62 impulsive violent recidivist offenders with early-onset (type 2) alcoholism, 123 late-onset nonviolent (type 1) alcoholics, and 267 race and gender-matched controls. The allele and genotype frequencies of these groups were compared with each other and also with previously published data from 3,140 Finnish blood donors. The type 2 alcoholics did not differ from either the blood donors or the controls. The low activity (L) allele frequency was higher among type 1 alcoholics (chi(2) = 4.98, P = 0.026) when compared with type 2 cases. The odds ratio for type 1 alcoholism as compared with type 2 alcoholism for those subjects with the LL genotype versus the HH genotype was 3.0 (95% confidence interval 1.1-8.4, P = 0.017). The results suggest that COMT genotype has no major role in the development of early-onset alcoholism with severe antisocial behavior.

Adult↗

Impulsivity as an underlying factor in the relationship between disordered eating and sexual behavior.

OBJECTIVE: Previous research has reported associations between bulimia nervosa (BN), increased sexual activity, and impulsivity. However, most studies have examined these topics separately and have not examined the role of impulsivity in associations between bulimic and sexual behaviors. The current study sought to examine relationships between disordered eating, sexual behaviors, and impulsivity, as well as to investigate impulsivity as a third variable in these relationships. METHOD: The participants were 500 female undergraduate students from a large midwestern university who completed self-report questionnaires of binge eating, the use of compensatory behavior, sexual behavior, and impulsivity. RESULTS: Compensatory behavior, but not binge eating, was significantly correlated with sexual experiences. Partial correlations indicated that impulsivity is a third variable that partially underlies this relationship. CONCLUSION: Compensatory behaviors and increased sexual activity likely represent risky behaviors that are influenced by impulsivity levels.

Adolescent↗

Mean genes and the biology of aggression: a critical review of recent animal and human research.

Recent genetic work has suggested that abnormalities in serotonin biochemistry are directly causally linked to aggressive behavior, and there appears to be a consensus in the psychiatric literature that low levels of the serotonin metabolite 5-hydroxyindoleacetic acid (5-HIAA) in cerebrospinal fluid are specifically associated with impulsive violent behavior. We review the limitations of the genetic studies and conduct a meta-analysis of 39 studies linking 5-HIAA to aggression in humans. No differences in mean 5-HIAA levels were found between groups of violent impulsive psychiatric patients and groups of subjects diagnosed with other psychiatric or medical conditions not considered to involve violence once these levels had been corrected for three nonpsychiatric sources of variation (age, sex and height). However, mean 5-HIAA levels in both of these groups were lower than the mean corrected level in groups of normal healthy volunteers. The results confirm an association between low 5-HIAA levels and psychiatric disorders, but fail to support any specific relationship between low 5-HIAA levels and impulsive aggression or criminality. It is premature and misleading to speak of "mean genes" (Hen 1996) or a specific neurochemistry of aggressive behavior.

Aggression↗

An operant counting scale for children: A preliminary methodological psychoactive-drug case study.

This pilot study is the first attempt at objective measurement of well-defined molecular behaviors through covert field observation. Though the main thrust is the development of a methodology for the clinical investigation of drug effects on children, a method that minimizes or overcomes many of the special problems that have plagued child drug research in the past, some preliminary data on the behavioral effects of haloperidol and imipramine were obtained. The technique developed is called an operant counting scale, and it promises to be useful in future full-drug studies.

Adolescent↗