[Complement activity of blood serum and the agglutinin titer after ultraviolet irradiation].
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BACKGROUND: Vitiligo is an acquired pigmentary skin disorder that affects 0.5-2% of the population. Many patients contact their physician and alternative therapists for help. This review article presents an update of knowledge about vitiligo and is aimed at physicians that treat this patient group. METHOD: The article is based on literature identified on PubMed, textbooks in Dermatology and supplemented by clinical experience. RESULTS AND INTERPRETATION: Vitiligo is characterized by the absence of melanocytes in skin and hair follicles. The pathogenesis is complex with genetic, autoimmune and toxic contributors. Clinically well-defined milk-white maculae are seen in the skin, with a wide variety of spread and distribution. The debut of vitiligo is often in childhood and adolescence. Investigations indicate that vitiligo affects quality in life for both children and adults. Treatment of vitiligo is a challenge. Phototherapy with narrowband UVB or topical therapy with tacrolimus ointment or potent steroids may be indicated in some cases, but the effect is not well documented.
The results of sparing operations of 576 children with benign tumors and tumor-like bone affections have been analysed. There have been revealed the advantages of the complex method of treatment, envisaging the sparing approach to the damaged segment, thermal treatment of the residual osseous walls by means of CO2--laser and recipient-like plasty of the operational defect (UV--irradiated autologous bone marrow+allomaterial): absence of recurrencies, complete restoration of the bone structure in 9-12 months after the operation.
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Association between baths with the thermal water of Comano Springs and selective photo-therapy UVB (bath-photo-therapy) has proved to be effective in 94% of psoriatic patients with non-extensive disease. Therefore bath-photo therapy represents a valid alternative to traditional topical treatments and can be used as a adjuvant in the interval periods of the aggressive modern therapy.
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