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At least 739 records · Page 41Linked to original sources
PubMed2003

Changes in the expression of tyrosine hydroxylase (TH), dopamine beta-hydroxylase (DBH), galanin (GAL), vasoactive intestinal polypeptide (VIP) and substance P (SP) in the uterine cervix-projecting neurons located in the lumbar paravertebral ganglia of the pig.

The uterine cervix-projecting neurons located in the lumbar paravertebral ganglia were identified by retrograde tracing. These contained immunoreactivity to TH and DBH. No immunoreactivity to GAL, VIP and SP was found in the neurons. Extirpation of the uterus reduced the expression of TH and induced the expression of GAL in the neurons. Expression of other substances studied was unchanged.

Animals↗
PubMed2003

Differences in the chemical coding of nerve fibres supplying major populations of neurons between the caudal mesenteric ganglion and anterior pelvic ganglion in the male pig.

The present study was designed to investigate and to compare the chemical coding of nerve fibres supplying major populations of neurons in the caudal mesenteric (CaMG) and anterior pelvic (APG) ganglion in juvenile male pigs (n=5) using double-labelling immunofluorescence. The co-existence patterns of some biologically active substances including tyrosine hydroxylase (TH) and vesicular acetylcholine transporter (VAChT) as well as vasoactive intestinal polypeptide (VIP), substance P (SP), calcitonin gene-related peptide (CGRP), Leu5-enkephalin (LENK) and serotonin (5-HT) were analysed under a confocal laser scanning microscope. Profound differences in the neurochemical features of the nerve terminals between the ganglia were observed. Moreover, there were also distinct differences in the chemical coding of nerve fibres associated with the particular populations and subpopulations of neurons within the ganglia. In both ganglia, nearly all adrenergic and cholinergic neurons were supplied with VAChT-positive nerve fibres (putative preganglionic fibres). However, in the CaMG, they were more numerous and, in contrast to the APG, many of them also stained for VIP. In the APG, a great number of nerve terminals expressed immunoreactivity to SP and CGRP (putative collaterals of sensory neurons). Interestingly, they densely supplied almost exclusively adrenergic neurons. SP-positive nerve fibres were moderate in number in the CaMG, but, in addition to VAChT-IR nerve terminals, the most numerous populations of nerve fibres in this ganglion were those expressing highly colocalized immunoreactivities to CGRP and LENK, and those which stained for 5-HT (putative processes of enteric neurons). However, these fibres supplied almost exclusively larger, intensely stained for TH and clustered adrenergic neurons. This diversity of the nerve terminals reflects the complexity of nerve circuits involved in the innervation of structures supplied by neurons in the porcine CaMG and APG. It also demonstrates the importance of nerve inputs for the proper function of autonomic neurons and thus their target tissues.

Animals↗
PubMedDate not supplied

Usefulness of bipolar scissors for rectal cancer surgery with autonomic nerve preservation.

BACKGROUND/AIMS: Pelvic autonomic nerve preservation for rectal cancer has become more common in recent years. Therefore, we evaluated the usefulness of bipolar scissors for this procedure. METHODOLOGY: This study included 30 consecutive patients with lower rectal cancer who underwent pelvic autonomic nerve preservation at our hospital between April 1998 and August 2001. The bipolar scissors group comprised 10 patients who received the procedure using bipolar scissors, while the conventional group included 20 patients who received the procedure without the use of bipolar scissors. The two groups were compared in terms of operating time, blood loss, postoperative urinary and sexual function. RESULTS: Blood loss in the bipolar scissors group was 394.4 +/- 201.8mL, which was a significantly lower volume than that in the conventional group (881.8 +/- 582.9ml) (p=0.0049). All the patients in the bipolar scissors group (10/10=100%) and 19 cases in the conventional group (19/20=95.0%) answered that they were satisfied with the results of their voiding function. In the bipolar scissors group, 100% were capable of erection (5/5) and 80.0% preserved ejaculation (4/5). In the conventional group, 100.0% (10/10) and 77.8% (7/9) preserved erection and ejaculation, respectively. CONCLUSIONS: The use of bipolar scissors is quite beneficial when patients with rectal cancer receive pelvic autonomic nerve preservation.

Aged↗
PubMed2004

Development of the myelin sheath of the hypogastric nerves in a human foetus aged 23 weeks.

The formation of the myelin sheath of the human hypogastric nerves was studied by electron microscopy in a foetus of 23 weeks of postovulatory age (220 mm C-R length). In the investigated foetus the hypogastric nerves were mainly composed of bundles of unmyelinated fibres. The myelinated fibres were seen to be at different stages of myelination. Well myelinated fibres had thick compact laminated myelin. The number of myelin lamellae on a single fibre was 22.

Fetus↗
PubMed2004

[Ilioinguinal/iliohypogastric nerve block for pediatric inguinal herniorrhaphy; evaluation of the dose of ropivacaine].

BACKGROUND: The aim of this study was to investigate the appropriate dose of ropivacaine in efficacy and safety when administered for ilioinguinal/iliohypogastric nerve block in children undergoing inguinal herniorrhaphy. METHODS: Forty six children (aged 1-8 yr, classified ASA I-II) undergoing ambulatory surgery for inguinal herniotomy were randomly assigned to one of the three groups, according to the dosage of ropivacaine: group I (n = 15), group II (n = 16) and III (n = 15) received 1.875, 0.9375 and 0.5625 mg x kg(-1) of ropivacaine, respectively. Intraoperative hemodynamics and modified CHEOPS score at 1, 3 and 5 hours after operation were recorded. RESULTS: There were no significant differences among the three groups in the intraoperative hemodynamics, whereas postoperative modified CHEOPS scores were significantly higher in group III than the other groups. Trivial femoral nerve palsy occurred in one patient of the group II, and no other adverse effects were seen in any groups. CONCLUSIONS: These results suggest that more than 0.9375 mg x kg(-1) of ropivacaine might be recommended to obtain sufficient postoperative analgesia for the ilioinguinal/iliohypogastric nerve block in children undergoing inguinal herniorrhaphy.

Amides↗
PubMed2005

Surgical management of 33 ilioinguinal and iliohypogastric neuralgias at Louisiana State University Health Sciences Center.

OBJECTIVE: This is a retrospective review of 33 charts of patients with ilioinguinal and iliohypogastric neuralgias who underwent a neurectomy at Louisiana State University Health Sciences Center between 1967 and 2000. Operations associated with neuralgias and postoperative pain outcomes were analyzed. METHODS: There were 23 ilioinguinal and 10 combined ilioinguinal-iliohypogastric neuralgias, and the side of the lesion and sex of the patient were found to be evenly distributed in this group. Nerve blocks must have resulted in a complete or substantial decrease in pain before a neurectomy was recommended. Twenty-nine (88%) of 33 neuralgia patients had injuries from iatrogenic causes, and 4 (12%) injuries were caused by blunt trauma. In the 23 isolated ilioinguinal neuralgias, the operation associated with neuralgias in 13 (57%) of 23 patients was a herniorrhaphy. This was followed by 4 (17%) neuralgias after an appendectomy and 3 (13%) after a hysterectomy. Three (13%) patients had neuralgias resulting from blunt trauma. Nine (90%) of 10 ilioinguinal-iliohypogastric lesions were caused by iatrogenic causes, and 1 (10%) neuralgia resulted from blunt trauma. A neurectomy was performed in all patients. RESULTS: The neurectomy resulted in considerable pain relief in 21 (91%) of 23 patients with ilioinguinal lesions and 9 (90%) of 10 patients with ilioinguinal-iliohypogastric lesions. Postoperative side effects were persistent numbness below the resected nerve and loss of the cremasteric reflex. Minor postoperative complications consisted of two superficial skin infections. CONCLUSION: Ilioinguinal and ilioinguinal-iliohypogastric neuralgias are infrequent conditions; however, 33 patients from the Louisiana State University Health Sciences Center were accrued and analyzed in this study, and most had significant pain relief after neurectomy.

Female↗
PubMed2004

Use of chronic sacral nerve stimulation in neurological voiding disorders.

AIM: Neurogenic low urinary tract dysfunctions unresponsive to medical and conservative therapy are difficult to manage. Nowadays they can be treated with Sacral Nerve Stimulation (SNS), even if clinical experiences reported in literature are still limited. METHODS: We performed SNS in 6 patients with neurogenic bladder: 3 patients had incontinence-urgency (1 myelitis, 1 multiple sclerosis, 1 autonomic polineuropathy) and 3 patients had urinary retention (1 incomplete spinal cord lesion, 1 operation for discal hernia T5-T6, 1 hysterectomy). RESULTS: Among cases with incontinence-urgency we achieved complete control of the bladder in 2 patients while in 1 patient the number of urinary losses was reduced of the 80%. In 2 patients with urinary retention we obtained complete recovery of the bladder function, while in 1 patient the number of cateterisms/die reduced of 50%, the urinary volume for micturion increased and residual urinary volume decreased. Results were unchanged during the follow-up (maximum 26 months), except for 1 patient in which a partial loss of effectiveness occurred. CONCLUSIONS: Chronic electric stimulation of S3 sacral roots via an implanted neuroprotesis is therefore an effectiveness, save and promising therapeutic option in treatment of neurogenic bladder dysfunctions.

Electric Stimulation Therapy↗
PubMed2005

Nerve cells and synapses in the human foetal hypogastric nerves.

The hypogastric nerves of a human foetus of 220 mm C-R length (23(rd) week) were investigated with an electron microscope. These nerves were composed mainly of bundles of unmyelinated fibres and single myelinated fibres. Small ganglia and single ganglion cells were observed in the hypogastric nerves. Light and dark cells were found among the nerve cells. The two types of cell differed in the number of ribosomes and the amount rough endoplasmic reticulum. In the period of development investigated protosynapses and mature synapses were observed in the hypogastric nerves.

Endoplasmic Reticulum, Rough↗
PubMed2006

[Extended radical resection with nerve-preservation for rectal cancer].

OBJECTIVE: To investigate the clinical value of extended radical resection with nerve- preservation for rectal cancer. METHOD: Ninety-eight patients with rectal cancer received extended radical resection with nerve- preservation in our hospital. The questionnaire were used to collect the data of the patients urination and sexual function. The survival was analyzed retrospectively. RESULTS: 62.3% (61/98) of the patients could erect normally and 57.1% (56/98) of the patients had normal sexual function. The average time of catheterization in 57 patients was 60 hours, the residual urine volume (RUV) was 28 ml and the max-micturition-desire urine volume was 400 ml. The 5-year survival rate of those who underwent extended radical resection with nerve-preservation was 61.2%. CONCLUSION: Extended radical resection with nerve-preservation,which could decrease the incidences of post-operative urination and sexual dysfunction, and have not affect the survival, was the most optimal operation for rectal cancer.

Adult↗
PubMed1991

[Anesthesiology problems in Takayasu's syndrome].

Takayasu's disease is a rare form of nonspecific obliterative panarteritis of unknown origin, mainly located at supraaortic, renal, and pulmonary arteries and resulting in multiple stenoses and occlusion of major arteries. Predominantly young women in the first three decades of life are affected. Absence of arm pulses, vascular bruits, and retinopathy are classic symptoms. Another symptom is hypertension of the lower extremities and hypotension of the upper extremities, thus potentially impairing cerebral perfusion. A 25-year-old female patient with a 2-year history of Takayasu's disease presented for therapeutic abortion on the grounds of her medical condition. There were significant stenoses of the left common carotid artery and the internal carotid artery. The left subclavian artery was totally obliterated. The arterial blood supply to the left arm was accomplished by the left vertebral artery via a subclavian steal syndrome. Brachial and radial pulses were absent in both arms. General, spinal or epidural anesthesia can produce arterial hypotension. Blood pressure assessment at the lower extremities does not allow conclusions about perfusion of supraaortic arteries and cerebral perfusion pressure. Thus, a paracervical block was performed; sedation and analgesia were achieved with small doses of midazolam and alfentanil. We planned that if general anesthesia became necessary we would induce anesthesia with etomidate and alfentanil and maintain anesthesia by mask ventilation with nitrous oxide in oxygen and supplementary doses of alfentanil. Invasive monitoring such as arterial or Swan Ganz catheterization, was contraindicated because of the possibility that inflamed vessels would become irritated. Therefore, we only monitored ECG, blood pressure at the leg, ventilation parameters, and oxygen saturation at the ear lobe by pulse oximetry.(ABSTRACT TRUNCATED AT 250 WORDS)

Abortion, Therapeutic↗
PubMed1991

Preservation of ejaculation in stage I non-seminomatous testicular tumours.

The loss of ejaculation is the most serious postoperative complication of patients having stage I non-seminomatous testicular tumours. In order to preserve the capability for ejaculation even after retroperitoneal lymphadenectomy (RPA) the preservation of paravertebral sympathetic ganglia but that of the sympathetic nerves in the territory of aortic bifurcation and common iliac arteries to be ulcessary.

Aorta↗