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[Health status, social networks and support systems of elderly men and women in a large city and in former coal-mining areas--a population-based comparative study of 70-year-old residents of Sapporo and Yubari].

In order to analyze the different features of the social network, social support system and health status of elderly people, a survey was performed of the social environment and health related issues among 70 year-old men and women in Sapporo, a large city, and Yubari, a small city which has experienced coal mine closures, both in Hokkaido prefecture. The results were as follows: 1. In Yubari, the health status of the elderly living alone was better than those with other familial categories such as living with their spouse, or with the families of their children. In contrast, the status of the elderly living alone in Sapporo was worse than the others. The mean numbers of out-patient visits and hospital admissions during the previous one year were higher among elderly people living alone in both areas. 2. There were large differences in social support and social network in the two areas and among the living status of the elderly. In particular, persons living alone in Sapporo had statistically significantly lower amount of support than others. Elderly people in Sapporo had fewer contacts with their neighbors and only a small number of them participated in community-based social associations compared with the same age groups in the city of Yubari. 3. An extremely small number of the elderly were provided formal support from official personnel such as public health nurses, district welfare commissioners and so on. The results of this study suggest the need for more formal and informal networks to provide for social support for those elderly men and women living alone in large cities.

Aged↗

Social and geographic distance in HIV risk.

OBJECTIVE: The objective of this study was to examine the relationship between social distance (measured as the geodesic, or shortest distance, between 2 people in a connected network) and geographic distance (measured as the actual distance between them in kilometers [km]). STUDY: We used data from a study of 595 persons at risk for HIV and their sexual and drug-using partners (total N = 8920 unique individuals) conducted in Colorado Springs, Colorado, from 1988 to 1992--a longitudinal cohort study that ascertained sociodemographic, clinical, behavioral, and network information about participants. We used place of residence as the geographic marker and calculated distance between people grouped by various characteristics of interest. RESULTS: Fifty-two percent of all dyads were separated by a distance of 4 km or less. The closest pairs were persons who both shared needles and had sexual contact (mean = 3.2 km), and HIV-positive persons and their contacts (mean = 2.9). The most distant pairs were prostitutes and their paying partners (mean = 6.1 km). In a connected subset of 348 respondents, almost half the persons were between 3 and 6 steps from each other in the social network and were separated by a distance of 2 to 8 km. Using block group centroids, the mean distance between all persons in Colorado Springs was 12.4 km compared with a mean distance of 5.4 km between all dyads in this study (P <0.0001). The subgroup of HIV-positive people and their contacts was drawn in real space on a map of Colorado Springs and revealed tight clustering of this group in the downtown area. CONCLUSION: The association of social and geographic distance in an urban group of people at risk for HIV provides demonstration of the importance of geographic clustering in the potential transmission of HIV. The proximity of persons connected within a network, but not necessarily known to each other, suggests that a high probability of partner selection from within the group may be an important factor in maintenance of HIV endemicity.

Cluster Analysis↗

Architecture of an image capable, Web-based, electronic medical record.

With each medical center department creating and maintaining its own patient care-related data, nursing and house staff may find it confusing to log into all the information systems necessary to achieve a global perspective of the patient's state. The Medical Information Network Database application provides a logically centralized Worldwide Web viewing application for the physically distributed data. In addition to coordinating data displays for histories, laboratories, pathology, radiology, and discharge summaries, the application can be configured to apply rule sets to the data and remind caregivers of follow-up tests or of possible reactions to treatment protocols. The viewing client runs on any HTML 2.0-compliant browser, although certain applet enhancements (notably for viewing radiological images) require a browser with Java abilities. With this "thin client" approach, the application can be configured to coexist with other applications (such as a PACS viewer), thus centralizing information and reducing the overall number of computers in the medical center.

Computer Systems↗

Reinventing vital statistics. The impact of changes in information technology, welfare policy, and health care.

Vital statistics offers a case study in the potential of new information technology and reengineering to achieve better public sector performance. New technology--notably the shift from a paper to an electronic process for recording vital events and transmitting the data to public agencies--is creating opportunities to produce more timely, accurate, and useful information. The furthest advanced innovation is the electronic birth certificate. At the same time, changes in welfare policy and health care--including efforts to establish paternity at the time of birth and to improve health care outcomes--are creating pressures for more policy-relevant data about vital events. In addition, the rise of integrated health plans and health information networks is radically altering the organizational context of vital statistics. On the basis of a State-by-State survey of vital statistics officials, the authors estimate that at the end of 1994, 58 percent of all births in the United States were being recorded on an electronic birth certificate and communicated to a public agency electronically. Nearly all respondents reported that the electronic birth certificate brought improvements in both timeliness and accuracy of data. Achieving the full promise of the new technology, however, will require more fundamental changes in institutions and policies and a reconceptualization of the birth certificate as part of a broader perinatal information system.

Birth Certificates↗

[The most frequent allergens in allergic contact dermatitis].

BACKGROUND AND OBJECTIVE: The prevalence of allergic contact dermatitis is high. Patch testing is the standard procedure to detect contact sensitivity. More than 3000 allergens are known, today. On the basis of the data of this study the top allergens are presented. PATIENTS AND METHODS: The retrospective analysis is based on the patch test results collected by the Information Network of Departments of Dermatology in 2004. Data of 9948 patients (6175 female und 3773 male) referred for the evaluation of suspected contact allergy were analysed to determine the frequency of sensitization to the 10 most common contact allergens. RESULTS: The top ten allergens were nickel sulphate (frequency of sensitization standardized for sex and age 17.2 %), fragrance mix (7.2 %), balsam of Peru (6.7 %), cobalt chloride (6.5 %), potassium dichromate (5.3 %), colophony (4.6 %), lanolin alcohol (4.3 %), p-phenylenediamine (4.2 %), ammoniated mercury (3.5 %) und methyldibromoglutaronitrile/phenoxyethanol (3.4 %) in 2004. CONCLUSIONS: Even after healing of the skin lesions of allergic contact dermatitis, it must be considered that sensitization persists indefinitely. Therefore, patients have to be informed exactly about their relevant contact allergens to ensure complete avoidance. To do so, physicians need a detailed knowledge of the most common contact allergens which are discussed in this paper.

Adult↗

A multi-agent softbot to retrieve medical information on Internet.

World-Wide Web is a media where information is unstructured, distributed, multimedia and multilingual. Many tools have been developed to help users search for information: subject hierarchies, general search engines, browsers and search assistants. Although helpful, they show serious limitations, mainly in terms of precision, multilingual indexing and distribution. The M.A.R.V.I.N. project (Multi Agent Retrieval Vagabond on Information Networks) proposes solutions with a distribution of the indexing task in agents specialized in a given domain. M.A.R.V.I.N. has been successfully applied to the medical domain. The medical index and its associated search engine MedHunt (Medical Hunter) demonstrate the interest of such an approach with currently 50,000 indexed medical sites and more than 100,000 accesses each month.

Abstracting and Indexing↗

[Structure of communication between physicians and patients from the viewpoint of community health].

Understanding the structure and problems of communication between physicians and patients should be achieved before introducing a medical information network system for community health. To this end a questionnaire survey was performed on 2,362 patients who saw physicians in medical facilities in a certain district of Hiroshima city. As a result, it was revealed that 'explanations given by doctors' and 'explanatory ability of patients' were mutually closely related and formed a basis for other aspects of communication and patient behavior. Satisfaction with the explanation given by physicians declined with examination time of less than 5 minutes and examination in hospitals rather than in clinics. Explanatory ability of patients decreased as age of patients increased and showed a remarkable decrease in patients of more than 80 years old. This suggested the existence of risk that information necessary for safe examinations may not be transmitted to physicians. These results pointed out the importance of a supporting system of communication especially for the elderly patient.

Communication↗

A Multi-Source Information System via the Internet for End-Stage Renal Disease: Scalability and Data Quality.

A Multi-Source Information System (MSIS), has been designed for the Renal Epidemiology and Information Network (REIN) dedicated to End-Stage Renal Disease (ESRD). MSIS aims at providing reliable follow-up data for ESRD patients. It is based on an n-tier architecture, made out of a universal client, a dynamic Web server connected to a production database and to a data warehouse. MSIS is operational since 2002 and progressively deployed in 9 regions in France. It includes 11,500 patients. MSIS facilitates documenting medical events which occur during the course of ESRD patient' health care and provides means to control the quality of each patient's record and reconstruct the patient trajectory of care. Consolidated data are made available to a data warehouse and to a geographic information system for analysis and data representation in support of public-health decision making.

Data Accuracy↗

RCoxNet: A Deep Learning Framework Integrating Random Walk with Restart, Mutation, and Clinical Data for Cancer Survival Prediction.

Accurate survival prediction in cancer remains challenging due to the sparsity of somatic mutation profiles and the failure of existing models to capture higher-order gene-gene dependencies. Network diffusion methods such as Random Walk with Restart (RWR) can propagate mutation signals across protein-protein interaction (PPI) networks to address sparsity, yet their integration within a deep learning Cox survival framework has not been comprehensively benchmarked across multiple cancer cohorts. We present RCoxNet, a deep learning framework that maps somatic mutation profiles onto a ConsensusPathDB-derived PPI network via RWR, selects prognostic genes by log-rank filtering, and processes network-informed mutation scores through three fully connected hidden layers feeding into a Cox proportional hazards output. RCoxNet was evaluated on The Cancer Genome Atlas (TCGA) cohorts for four cancer types (breast invasive carcinoma [BRCA], lung adenocarcinoma [LUNG], glioblastoma multiforme [GBM], and ovarian serous cystadenocarcinoma [OV]) using 20 independent random splits. The model achieved mean C-index values of 0.807 &#xb1; 0.044 (BRCA), 0.750 &#xb1; 0.039 (LUNG), 0.704 &#xb1; 0.041 (GBM), and 0.668 &#xb1; 0.036 (OV), consistently outperforming DeepSurv, Cox-nnet, SurvivalNet, Cox Elastic-Net (Cox-EN), and DeepHit, with statistically significant gains over Cox-EN, Cox-nnet, SurvivalNet, and DeepHit across the majority of cohorts. RCoxNet demonstrates that embedding sparse mutation profiles into a PPI network context substantially improves cancer survival prediction and yields biologically interpretable prognostic features relevant to precision oncology.

cancer survival prediction↗

Identifying indicators of laboratory management performance: a multiple constituency approach.

The challenges for laboratory management posed by cost control, managed care, organizational restructuring, information networking and health system integration call for new measures to evaluate how effectively laboratories manage emerging performance expectations. This study identifies the Delphi panel method in achieving consensus on measures of effectiveness and considers a specific application, the identification of indicators of laboratory performance, from the perspective of key constituencies.

Attitude of Health Personnel↗

Databases, websites, and the Internet.

By the end of the year 2000, an estimated 100 to 500 million computers may be linked to the Internet, representing an enormous level of information exchange. Even today, a broad Internet search of a term such as "breast cancer" can produce an overwhelming list of web pages, most of which will not be of interest to the typical Internet user. A more sophisticated user such as the oncology professional will more likely refine the search by adding other terms, producing a more manageable and useful list of websites. Information on cancer can be readily accessed from thousands of websites developed by the government, medical organizations, other institutions, medical journals, patient support groups, and pharmaceutical companies, as well as through medical web directories. The Cancer Information Network (CIN), an independent website geared to the oncology community, provides access to Medline, PDQ, and hundreds of cancer-related resources on the World Wide Web. CIN also offers the complete NCCN conference proceedings and practice guidelines; full text of several medical journals, textbooks, and handbooks; a daily oncology news service; a clinically oriented drug reference guide; and an extensive calendar of medical meetings and CME courses.

Databases as Topic↗

Social-psychological factors affecting help-seeking for emotional problems.

Predictors of the attitudinal measure of orientation toward help-seeking for emotional problems have been shown to include demographic, network, and personality variables. This research determined whether these same variables predict the behavioral outcome measure of help-seeking, both in general and from professional services in particular. Help-seeking in response to emotional problems was studied in a sample of Australian adolescents. General help-seeking was predicted by more symptoms of psychological distress, being female, availability of social support, knowing someone who had sought professional help, and the personality characteristics of high private self-consciousness and willingness to disclose mental health. When only those with evident emotional distress were considered, only gender and willingness to disclose remained significant predictors. These same variables did not account for those who sought professional help rather than relying upon their informal network. Level of psychological distress was the only significant predictor of professional consultation. Psychological symptoms and gender were shown to be more relevant predictors of the behavioral measure of help-seeking than network or personality characteristics.

Adolescent↗

Project document drafted to revitalize population education.

In the pipeline is the recently developed draft project document aimed at revitalizing and strengthening the population education in the country. It is now under review and approval. To reactivate the population education program, the project calls for the issuance of an Executive Order by the Department of Education, Culture and Sports to create a national Population Education Center and the establishment of 15 Regional Population Education Offices and 133 population education desks at the divisional level. This institutional network will ensure the nationwide implementation of population education program. It will also update and revise some existing curricula and develop new teaching/learning materials for kindergarten, elementary and university level as well as packages for learners and fieldworkers of nonformal education. The first baseline activities to accomplish this are to review the existing curricula for population education messages from kindergarten to grade 11 and university level as well as a survey to determine population learning needs of pupils and teachers from kindergarten to university level. The project will also go into training and re-training of project staff, trainers at national and regional levels, 2000 new teachers and 1000 formerly trained teachers and 17 documentation/library assistants. Strengthening of its Documentation Center and setting up to an information network will also be undertaken. Thus, by the end of the project, it is envisaged that about half a million students and 2500 educators would have increased their knowledge and developed positive attitudes towards population-related concepts.

Asia↗

Sex offender community notification: examining the importance of neighborhood meetings.

Within the last decade, federal and state laws have been passed authorizing or requiring the notification of local residents that a convicted sex offender will be released and living in their neighborhood. The community meeting method of notifying neighborhood residents, although the subject of extensive news media attention, has been largely overlooked by empirical researchers. This study focuses on the experience of residents who attend such meetings and how that experience factors into a collective response on the part of the community. Data are derived from attendee surveys and recorded observations taken at all community notification meetings held throughout Wisconsin during a nine month period. The findings suggest that community notification meetings, if properly conducted, can perform an important role in managing the behavior of known sex offenders in the community. However the decision to notify and involve the public in an informal network of neighborhood surveillance may come at the cost of increased community anxiety. This anxiety is related to how the attendees were notified of the meeting, how clearly the purpose of the meeting was conveyed, and how organized the meeting appeared to the audience. Suggestions on how to more effectively utilize the community meeting method of notification are presented.

Adult↗

Use of patient education and monitoring software in community pharmacies.

OBJECTIVE: To determine the level of use of health education and monitoring software programs in independent community pharmacies in rural locales. DESIGN: The use of seven software programs that deliver patient education and provide blood pressure monitoring was assessed at five sites of the Nebraska Drug Information Network (NDIN) for one month. Direct Access, a Windows-based software program, documented which programs were accessed and for what time period. RESULTS: During a one-month period, 326 accesses were logged representing 44 hours of computer time. Extrapolated to all 30 sites of NDIN, this represents 264 hours and 1,956 accesses monthly. On average, each pharmacy logged 8.8 hours within 65 accesses each month. Each access averaged 8 minutes. DynaPulse (167 accesses; 16.4 hours) was the most frequently used product, followed by Home Medical Advisor Pro (54 accesses; 8.9 hours) and Mayo Clinic The Family Pharmacist (35 accesses; 8.3 hours). The least amount of time was spent with BodyWorks (0.6 hours) but Wellness Checkpoint had fewest accesses (7 accesses). CONCLUSION: Applied medical informatics is assuming a larger role in daily clinical practice as pharmacy practitioners strive to better inform their patients. This is congruent with the finding that a better informed public can be a healthier public. This study demonstrates that computer systems are readily used by patients and pharmacists in rural communities.

Adult↗

How much does social capital add to individual health? A survey study of Russians.

Some Russians are healthier than others. To what extent does their health vary with involvement or exclusion from social capital networks? The first section reviews alternative theories: human capital as the primary determinant; social capital, whether generic, situation-specific or simply a new label for old measures of social integration; or a composite theory--both human and social capital are major determinants of health. The evidence to test hypotheses consists of individual-level data about self-assessed physical and emotional health from the special-purpose social capital questionnaire used in the 1998 New Russia Barometer survey, a nationwide representative sample of the adult Russian population. Multiple regression analysis shows that on their own human capital and social capital each account for a notable amount of variance in health. When both forms of capital are combined in a composite model, each retains major influence, demonstrating that social capital does make an independent contribution to health. Significant social capital influences include involvement or exclusion from formal and informal networks; friends to rely on when ill; control over one's own life; and trust. Significant human capital influences besides age include subjective social status, gender and income. Regression-based estimates of impact show that social capital increases physical and emotional health more than human capital; together they can easily raise an individual's self-reported health from just below average on a five-point scale to approaching good health.

Adolescent↗

Contact sensitizations in metalworkers with occupational dermatitis exposed to water-based metalworking fluids: results of the research project "FaSt".

BACKGROUND: The composition of water-based metalworking fluids (wb MWF) is complex, and various admixtures may be added before or during usage. Wb MWF may cause irritant as well as allergic contact dermatitis. While several current case reports point towards allergens particularly related to wb MWF, systematic studies have not been performed for several years. From 1999 to 2001, a study on contact allergies among patients with occupational dermatitis (OD) called "Fruhzeitige Erkennung allergener Stoffe bei beruflicher und nicht-beruflicher Exposition" (German acronym: FaSt) was conducted by the Information Network of Departments of Dermatology (IVDK), funded by the employers' liability insurances in Germany (HVBG). OBJECTIVE: The objective of FaSt was to detect sensitization patterns related to particular occupational exposures. METHODS: Anamnestic and clinical data were gathered using a standardised questionnaire. Patch test results were recorded by computer within the IVDK routine procedure. In addition to descriptive statistical analyses, logistic regression analysis was performed to control the effect of potential confounders. RESULTS: Among the 1842 OD patients in the FaSt study, there were 160 metalworkers exposed to wb MWF, whose data is presented in this paper. A specific allergen pattern of these patients can be described: most frequently, sensitizations to monoethanolamine (MEA), colophony/abietic acid, and fragrance mix were observed. Additionally, cobalt, formaldehyde, formaldehyde releasers and other biocides are important allergens in these patients. CONCLUSIONS: Preventive measures and aimed in-depth research may be based on these results. The special MWF test series have to be kept up to date based on exposure information from the MWF industry and on continuous surveillance of the target group.

Adult↗

UMIN--key information infrastructure for the Japanese medical community.

University hospital Medical Information Network (UMIN) was established in 1989 as a collaborative project of national university hospitals in Japan funded by the Ministry of Education, Science, Sports, and Culture, and it started its Internet-based service for medical professionals in 1995. Since then, many services including those for academic societies and research groups have been added. Currently, due to batch registration of the members of large academic societies, the number of registered users and Web accesses are rapidly increasing (about 87,000 registered users and 4,500,000 page views in November, 2000). More than one hundred homepages of academic societies and research groups (including forty- two member-only ones) and one thousand mailing lists are operated. More than one hundred thirty academic societies collect abstracts using the UMIN server. All the Internet-based clinical and epidemiological research projects in Japan are now under way using UMIN. The characteristics of UMIN are its large variety of services and large number of user accounts of medical professionals, which are beneficial to both users and information service providers. UMIN is now important for some medical specialties and will be so for further ones in the future. UMIN is, in fact, evolving into a collaborative project of the Japanese medical community and is considered as its key information infrastructure.

Hospitals, University↗