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Barriers to osteoporosis identification and treatment among primary care physicians and orthopedic surgeons.

OBJECTIVE: To understand better the barriers among orthopedic surgeons and primary care physicians in identifying and treating possible osteoporosis in patients hospitalized with a fragility fracture sustained spontaneously or from a fall no greater than standing height. METHODS: A 1-page, 7-question survey was sent to 35 admitting orthopedic surgeons and 75 primary care physicians at a midwestern managed care organization in March 2001. Returned surveys were collected until 30 days had passed since the mailing. Primary care physicians were board-certified family practitioners and internal medicine physicians. All orthopedists were admitting surgeons in the hospital system. Responders were anonymous, and posted surveys were returned to the Orthopaedic Collaborative Practice office. The surveys were color-coded to separate responses from orthopedic surgeons and primary care physicians. RESULTS: Thirty-one surveys were returned: 23 (31%) from primary care physicians and 8 (23%) from orthopedic surgeons. Survey respondents agreed that the responsibility for postfracture attention to nutritional needs, including calcium and vitamin D, rested with the primary care provider. When asked about barriers to recommending bone mineral density testing with dual energy x-ray absorptiometry, 9 primary care physicians (39%) thought this type of testing was unnecessary for treatment, and 4 primary care physicians (17%) thought a barrier was caused by patient frailty. Primary care physicians indicated that potential adverse effects of medication (n=14 [61%]) and cost of therapy (n=13 [57%]) were the main factors limiting treatment. When asked to identify the single most important barrier in treatment, 14 physicians (61%) indicated cost was the greatest deterrent. Twenty-one primary care physicians (91%) reported they would be more likely to treat a patient with osteoporosis if a safe medication with proven fracture risk reduction were available. Primary care physicians indicated they were more likely to treat independently living adults (n=12 [52%]) and women compared with men (n=15 [65%]). All orthopedic surgeons (n=8) were willing for all patients to be evaluated in consultation with a nurse practitioner. Primary care respondents were less apt to agree with a nurse practitioner referral (n=5 [22%]). Both primary care physicians (n=16 [70%]) and orthopedic surgeons (n=4 [50%]) agreed that there is a need for increased primary care education about managing osteoporosis in patients hospitalized with low-impact fracture. CONCLUSIONS: Orthopedic surgeons were consistent in their opinion that postfracture attention to osteoporosis should rest with the primary care physician. Primary care physicians agree but report that cost and possible adverse effects of medication are major barriers to this care. Despite therapies for high-risk postfracture patients showing relative safety and proven efficacy in reducing future fractures, deterrents to this care are focused on cost and potential adverse effects. Further education is needed to promote a standard of care for the postfracture patient that is directed toward the prevention of a subsequent fracture.

Aged↗

[An infant with diffuse axonal injury].

Development of MRI enabled accurate and rapid diagnosis of head traumas which had been impossible with the conventional CT. The diagnosis of posttraumatic diffuse axonal injury (DAI) is a typical example. Most of the reported cases of DAI in childhood are of relatively older age, and DAI is rare in infancy. We report here a 1-year-9-month-old infant with DAI. After falling from two meters in height, he presented consciousness disturbance and a seizure that necessitated artificial respiration for half a day. He recovered completely without sequelae. Brain CT on arrival to the ER department was unremarkable, but MRI scans shortly thereafter showed typical findings of DAI. In childhood, DAI tends to be milder than in adult-hood, which may be explained by the age-dependent frequency of traffic accidents, and by anatomical and functional factors of a infant's brain. A large number of infantile cases should be accumulated to draw a more clearcut conclusion.

Brain↗

A review of paediatric maxillofacial injuries--a hospital-based study.

This study describes the patient profile with maxillofacial injuries attending a trauma unit at a children's hospital. A retrospective record-based analysis was carried out of children (less than 13 years of age) presenting with maxillofacial injuries from January 1991 to December 2001. Of the almost 90,000 trauma records, 13% of children presented with maxillofacial injuries. 60% were boys, with a quarter less than 3 years of age. Most presented with superficial lacerations and abrasions. The face (other than the facial bones) and the mouth/oropharnyx were most often injured. Injuries were mainly caused by falls from a variety of heights and transport-related injuries. Almost 60% of traffic-related injuries involved children as pedestrians being struck by a motor vehicle and 20% were cycle-related. Almost 70% of injuries occurred in or around their own home. Maxillofacial injuries in children are a significant cause of morbidity and its prevention especially in the home and streets needs urgent attention.

Age Distribution↗

[Injuries of the pelvis associated with injuries to other organs].

In polytraumatized patients with fracture of the pelvis and injury to the other organs, the clinical picture is dominated by a hypovolemic shock, which is difficult to control. Surgical intervention must be quick in cases of external or internal bleeding. The importance of reaching a quick diagnosis cannot be emphasized enough, upon which the life of the patient is greatly dependent. During the seven year period 23 patients with injury to the pelvis were treated. 10 had injuries to the surrounding organs (brain commotion, injury to the urethra and vagina, as well as the lower extremities). The causes were: automobile accidents (8), falling during play (6), from height (5), during sports (4). Two injured girls are individually described (2 1/2 and 8 years old), who were surgically treated successfully. There was no mortality.

Child↗

[Effect of the sympatholytic pirroxan on catecholamine excretion in experimental tetanus].

Excretion of catecholamines and vanilylmandelic acid was studied in rabbits with tetanic intoxication. It was found that catecholamine excretion increases up to 173% in the initial stages of the disease and falls to 51% at the height of the disease whereas excretion of vanilylmandelic acid progressively decreases down to 40% against normal. Pirroxan (10 mg/kg a day) reduces excretion of catecholamines and vanilylmandelic acid by three times, concurrently producing a definite cholinolytic effect.

Animals↗

Pediatric window-cord strangulations in the United States, 1981-1995.

OBJECTIVE: To document the prevalence of pediatric asphyxial death from window-covering cords in the United States and identify associated risk factors. DESIGN: Retrospective analysis of existing death certificate and incident files compiled by the US Consumer Product Safety Commission. SETTING: United States, 1981 through 1995. PATIENTS: Children aged 1 month to 8 years suffering unintentional traumatic asphyxiation from a window-covering cord. RESULTS: A total of 183 fatal window-cord strangulations were reported for the years 1981 through 1995, representing a mortality rate of 0.14 (95% confidence interval [CI], 0.10-0.18) per 100000 persons (< or =3 years old) per year in the United States. Ninety-three percent of victims were 3 years of age or younger. Pull cords on venetian-type horizontal window coverings accounted for 86% of documented injuries. Infant victims were more likely to become entangled while put down for a nap and toddlers were more likely to be suspended by the cord after falling or jumping from a height (P=.002). Window coverings remained anchored and did not undrape when substantial weight was suspended in the draw-cord loop. CONCLUSIONS: Window-covering cords represent a substantial strangulation hazard compared with other potentially harmful household products that were modified based on voluntary standards to mitigate the risk of injury. Product design modifications and parental education will be necessary to avert this type of fatal home injury.

Accidents, Home↗

Predictors for falls and fractures in the Longitudinal Aging Study Amsterdam.

The objective of this study was to identify easily measurable predictors for falls, recurrent falls, and fractures using a population-based prospective cohort study of 1469 elderly, born before 1931, in three regions of the Netherlands. The baseline at-home interview was in 1992. In 1995, falls experienced in the preceding year and fractures over the preceding 38-month period were registered. In a period of 1 year, 32% of the participants fell at least once, and 15% fell two or more times. The rate of recurrent falls was similar in men and women up until the age of 75 years. The total number of fractures was 85, including 23 wrist fractures, 12 hip fractures, and 9 humerus fractures. The incidence density per 1000 person-years for any fracture was 25.1 (95% confidence interval [CI], 18.9-31.4) for women and 8.2 (95% CI, 4.5-12.0) for men, respectively. Multiple logistic regression identified urinary incontinence, impaired mobility, use of analgetics, and use of antiepileptic drugs as the predictors most strongly associated with recurrent falls. Female gender, living alone, past fractures, inactivity, body height, and use of analgetics proved to be the predictors most strongly associated with fractures. The probabilities of recurrent falls were 4.7% (95% CI, 2.9-7.5%) to 59. 2% (95% CI, 24.1-86.9%) with zero to four predictors, respectively. The probability of fractures ranged from 0.0% (95% CI, 0.0-0.4%) without any of the identified predictors to 12.9% (95% CI, 4.4-32. 2%) with all six predictors present. Our study shows that the risk of recurrent falls and of fractures can be predicted using up to, respectively, four and six easily measurable predictors. This study emphasizes the importance of impaired mobility and inactivity as predictors for falls and fractures.

Accidental Falls↗

Weight-for-height standards in adulthood.

Although there are some Swedish studies giving reference values for height and weight in adulthood, no values of weight for height (W/H) are available. W/H is an essential measurement, as it permits comparison of weight independent of the height of an individual. We here present a method of constructing W/H standards, illustrated by a material sample of 4438 healthy individuals, 20-80 years of age, living in the Uppsala County during the period 1964-1971. In setting standards of W/H, the 'normal' increase in weight during adulthood and the distribution skewness of weight are both shown to be important. This weight gain starts at about 40 years of age, and is completed at approximately 55 years of age. It can be regarded as a 'normal' pattern, but not necessarily the optimum healthy one. Using ordinary growth charts for weight and height, a simple means of expressing W/H in standard deviation scores is outlined. It is difficult to find a representative Swedish sample, owing to geographical and psychosocial differences, and also to the secular trend phenomenon. However, the mean values for weight and height obtained in the present study fall between the mean values of two other recently conducted Swedish studies.

Adult↗

The effects of release height on center of pressure and trunk muscle response following sudden release of stoop lifting tasks.

BACKGROUND AND OBJECTIVES: Sudden release of load during lifting threatens postural stability and is countered by trunk muscle response, which can generate high loads on the spine, and may be a cause of tissue injury. The postural threat following sudden release and the consequent muscular response are likely to depend on the posture at the time of release. This study investigates the effects of sudden release of load at two release heights of one- and three-quarters of the knee to shoulder distance during stoop lifting. METHODS: Ten normal southern Chinese male volunteers were subject to sudden release of 20, 40, 60 and 80 N loads during stoop lifting trials. The release was randomly selected to be on the third, fourth or fifth cycle of a trial and was triggered at heights of one- and three-quarters of the total knee to shoulder lifting distance. The subjects stood on a force platform to allow the postural disturbance to be recorded by monitoring the center of pressure (COP), and electromyographic (EMG) data were collected from the rectus abdominus, internal oblique, external oblique, erector spinae and latissimus dorsi muscle groups. RESULTS: The COP excursion moved closer to the posterior limit of stability with increasing release load, and this effect was significantly more marked for release from the lower of the two heights. The minimum posterior COP separation from the posterior limit of stability was significantly less for the lower release height at all loads (p<0.001 in all cases). EMG data showed that the agonist-antagonist co-contraction durations were higher for the lower release height, and unlike sudden release from the higher level, showed a significant increase with increasing load. CONCLUSIONS: Sudden release at lower release height during stoop lifting results in significantly greater postural disturbance and spinal loading. The mean load predicted to result in fall or stumble at the lower release height (133 N) is significantly less than that predicted at the higher of the two release heights (245 N). A more marked effect of release load is also seen in the postural disturbance and trunk muscle co-contraction time for the lower release height, and particular care should therefore be taken when handling potentially unstable loads under these conditions. If the security of the load cannot be guaranteed, storage at a higher level may reduce the risk of injury due to sudden release of the load.

Adult↗

Growth performance of Bangladeshi affluent school children (5-14 years).

A cross sectional anthropometric survey of 2045 healthy children (5-14 years) of affluent society of Dhaka City was done with the aim to compare their growth with the National Centre for Health Statistics (NCHS) standard. It was found that both weight and height of boys and girls of the studied children fall between 25th to 50th percentile of NCHS standard. In case of boys, body weight deviates below 25th percentile after 12 years whereas mean height is nearly parallel to 50th percentile up to 14 years. In case of girls, the pattern of growth is same except the fall below 25th percentile at the age of 8 and 9 years and the height remains above 25th percentile up to 12 years. It can be concluded that mean growth of affluent Bangladeshi school children is comparable to NCHS standard with minor variations.

Adolescent↗

Gait characteristics as risk factors for falling from trips induced in older adults.

BACKGROUND: Falls are a significant source of morbidity and mortality in older adults, with up to 53% of these falls due to tripping. To aid in preventing trip-related falls, the factors that increase an individual's risk of falling following a trip must be identified. This study investigated whether an older adult's gait influences their risk of failing following a trip. METHODS: Trips were induced during gait in 79 healthy, safety-harnessed, community-dwelling older adults using a concealed, mechanical obstacle. Associations between selected gait kinematic characteristics, recorded during normal walking, and the likelihood of falling following the trip were determined using logistic regression. RESULTS: Older adults who walked faster, took more rapid steps, or took longer steps relative to their body height had a significantly increased likelihood of falling following the trip. Step width, average trunk flexion during gait, and the phase of gait in which the trip occurred did not affect the likelihood of falling. A multivariable logistic regression model correctly classified 89.8% of trip outcomes based on two gait characteristics: step time and step length. As predicted from their gait characteristics, the subjects, as a group, had a low likelihood of falling following a trip, but selected individuals had a high likelihood of falling. CONCLUSIONS: The incidence of trip-related falls in healthy older adults is determined primarily by the frequency of tripping and not the ability to recover from a trip. Older adults can reduce their likelihood of falling following a trip by not hurrying while walking.

Accidental Falls↗

Cues to the perception of Taiwanese tones.

A labeling test with synthetic speech stimuli was carried out to determine to what extent the two dimensions of fundamental frequency (F0), height and movement, and syllable duration provide cues to tonal distinctions in Taiwanese. The data show that the high level vs. mid level tones and the high falling vs. mid falling tones can be reliably distinguished by F0 height alone, whereas the distinction between tones with dissimilar contours, such as the high falling and low rising tones, is predominantly cued by F0 movement. However, the other dimension of F0 may collaborate with the dominant one in cueing a tonal contrast, depending on the extent to which the two tones differ along that dimension. Syllable duration has a small additional effect on the perception of the distinction between falling and nonfalling tones. These results are consistent with previous findings in tone languages other than Taiwanese in that they suggest that tones are mainly cued by F0. While the primacy of F0 dimensions as cues to tonal contrasts depends on the contrast to be distinguished, the present findings show that tones which nominally differ only in register (e.g., high falling vs. mid falling) may exhibit perceptually relevant contour differences, and vice versa.

Communication Devices for People with Disabilities↗

[Effects of dihydrodinoreburnameninol on the electrical discharge of Torpedo marmorata under normal conditions and during hypoxia and anoxia. I].

The electric discharge of Torpedo M. can be considered as an index of the metabolic activity of the electric lobe of C.N.S. in groups of 10 torpedo the electric discharge was measured: the mechanical stimulus was obtained by the falling of different weights from a determinate height. Other 10 animals, to which the substance was administered, showed an increase of the electric discharge. The experiment was then repeated in conditions of hypoxia: a fall of the values of the electric discharge was observed. Finally the experiment was carried out considering the time: after 14 hours the condition of anoxia occurred.

Animals↗

Spontaneous growth in German children and adolescents with genetically confirmed Prader-Willi syndrome.

UNLABELLED: Height and weight in children with Prader-Willi syndrome, diagnosed by standard clinical criteria, follow a specific developmental pattern resulting in early childhood obesity, absent pubertal growth spurt and adolescent short stature. New molecular techniques (methylation analysis, fluorescence in situ hybridization) now allow the unequivocal diagnosis of Prader-Willi syndrome (PWS). We investigated the possibility of a bias in syndrome-specific growth standards based on clinically diagnosed patients by comparing these standards with new standards derived from 100 German patients with molecularly confirmed PWS, none of whom had received a growth-promoting therapy. Height centile curves of the German patients fall in the tall range of standards derived from American patients. This is mainly due to an elevation of the lower centile ranges in both sexes. When the height standards derived from German patients are compared to those of a large multinational cohort of patients, 78% of whom were not confirmed by genetic testing, only minor differences in the height centiles become apparent. The population background therefore does not appear to play a major role for the observed differences. In a marked proportion of patients a decreased sitting height/height ratio is found. This was usually associated with scoliosis. Weight standards from our study group show that after 14 y of age German girls with PWS are heavier than their American counterparts. Standards for the body mass index of German patients of both sexes are increased over normal reference standards (p < 0.0001) and do increase with age (boys: p = 0.0038; girls: p = 0.0004). PWS genotypes or sex had no apparent influence on SDS for height, weight and body mass index. CONCLUSIONS: Because of the observed differences to other growth standards, use of the newly constructed centile curves is advocated in German patients with molecularly confirmed PWS to avoid delay in the diagnosis of additional growth-compromising conditions.

Adolescent↗

Biomechanical properties of shoes and risk of falls in older adults.

OBJECTIVES: To determine the relationships between the biomechanical properties of shoes worn in a cohort of healthy older adults and the risk of falling. DESIGN: Nested case-control study, comparing biomechanical measurements of shoes worn by those who reported a fall with measurements of shoes worn by age- and sex-matched nonfallers engaged in broadly similar activities. SETTING: On-site measurements where falls occurred. PARTICIPANTS: A cohort of 1,371 older adults, of whom 327 reported a fall and 327 served as age- and sex-matched controls. MEASUREMENTS: Shoe measurements related to lateral stability (heel height and width, critical tipping angle), foot position sense (heel-collar height, sole thickness, and sole flexibility), and the shoe/surface interface (foresole material, shoe-to-ground coefficient of friction, sole contact area). RESULTS: Greater heel height was associated with increased risk of a fall (P for trend=.03), whereas greater sole contact area was associated with reduced risk (P for trend=.005). Shoe characteristics related to foot position sense bore little apparent relation to fall risk. Coefficients of friction of 0.5 or greater were observed in 93% of shoes measured, indicating that very few were excessively slippery. CONCLUSION: Certain measurable properties of shoes were found to be significantly related to risk of falls in older adults. Wearing shoes with low heels and large contact area may help older adults reduce the risk of a fall in everyday settings and activities.

Accidental Falls↗

Specificity of learning: why infants fall over a veritable cliff.

Nine-month-old infants were tested at the precipice of safe and risky gaps in the surface of support. Their reaching and avoidance responses were compared in two postures, an experienced sitting posture and a less familiar crawling posture. The babies avoided reaching over risky gaps in the sitting posture but fell into risky gaps while attempting to reach in the crawling posture. This dissociation between developmental changes in posture suggests that (a) each postural milestone represents a different, modularly organized control system and (b) infants' adaptive avoidance responses are based on information about their postural stability relative to the gap size. Moreover, the results belie previous accounts suggesting that avoidance of a disparity in depth of the ground surface depends on general knowledge such as fear of heights, associations between depth information and falling, or knowledge that the body cannot be supported in empty space.

Avoidance Learning↗

Fall arrest strategy affects peak hand impact force in a forward fall.

We measured the peak hand impact force involved in bimanually arresting a forward fall to the ground from a 1-m shoulder height in five healthy young males. The effects of three different subject instruction sets: "arrest the fall naturally"; "keep the head as far from the ground as possible"; and "minimize the peak hand forces" were studied by measuring body segment kinematics, ground reaction forces, and upper-extremity myoelectric activity. The hypotheses were tested that the (a) arrest strategy did not influence peak impact force, (b) arm configuration, impact velocity and upper-extremity electromyography (EMG) levels correlate to the peak impact force (c) and impacting the ground with one hand leading the other does not increase the impact force over that obtained with simultaneous hand use. The results show that these subjects were able to volitionally decrease the peak impact force at the wrist by an average of 27% compared with a "natural landing" (p=0.014) and 40% compared with a "stiff-arm landing" (p<0.0005). The magnitude of the peak unilateral wrist force varied from 0.65 to 1.7 body weight for these moderate falls onto a padded surface. Peak force correlated with the elbow angle at impact, wrist velocity at impact and with pre-EMG triceps activity. The force was not significantly higher for non-simultaneous hand impacts. We conclude that fall arrest strategy can substantially alter the peak impact forces applied to the distal forearm during a fall arrest. Therefore, the fall arrest strategy likely influences wrist injury risk independent of bone strength.

Accidental Falls↗

Evidence for a non-associative model of the acquisition of a fear of heights.

Theories that fear results from previous traumatic experience (i.e. conditioning theories) have enjoyed widespread support for over half a century. Recent research, however, has cast doubt on the validity of these models in some specific phobias. Two studies on the etiology of height phobia have obtained findings consistent with a non-associative, evolutionary explanation of fear acquisition (Menzies and Clarke, 1993a, Behaviour Research and Therapy, 31, 355-365; Menzies and Clarke, 1995a, Behaviour Research and Therapy, 33, 795-805). Unfortunately, the retrospective nature of these studies limits the conclusions that can be drawn from these data. Like all retrospective research, these studies depend on adult subjects imperfect ability to recall conditioning events that may have occurred many years earlier. The present investigation overcomes these methodological shortcomings by examining the relationship between putative conditioning events before the age of 9 yr and the presence of height fear at ages 11 and 18 yr in a large birth cohort studied longitudinally. To our knowledge this is the first study that has prospectively examined the relationship between relevant traumatic events early in life and the onset of height fear in late adolescence. No positive relationship was found between a history of falls resulting in injury (i.e. fracture, dislocation, intracranial injury or laceration) before the age of 9 and fear of heights at age 11 or 18. Interestingly, falls resulting in injury between the ages of 5 and 9 occurred more frequently in those without a fear of heights at 18 (P < 0.01)--a finding in the opposite direction to that predicted by conditioning theory but consistent with non-associative theories of fear acquisition. In general, the results provide strong support for non-associative models of fear and are difficult to reconcile with conditioning theories.

Accidental Falls↗