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At least 757 records · Page 42Linked to original sources

PubMed1985

Cysticercosis--review of 230 patients.

Two hundred thirty patients with cysticercosis were reviewed. Investigation with CT scan has led to a more detailed understanding of the natural history of human infestation which is essential to the evaluation of new pharmacological and neurosurgical treatments. In contrast to reports emphasizing the need to extirpate all intraventricular cysts, many of our patients needed only ventricular shunt implantation. The ability to evaluate and reevaluate hydrocephalus by CT scan permitted comfortable use of ventricular shunt insertion as the only treatment. Nevertheless, cysts in the fourth ventricle should nearly always be extirpated, because these cysts, by their mass effect, may cause herniation even after shunt implantation. Serious morbidity and death occur chiefly in patients who develop hydrocephalus from intraventricular and basilar infestation. It is unlikely that praziquantel will be effective in patients who present with symptoms of hydrocephalus.

Adult↗

PubMedDate not supplied

[2 cases of cysticercosis observed in Cameroon].

The authors report two observations of cysticercosis in two pigs breeders living in the western part of Cameroon. Microscopic observation of several pieces demonstrated the presence of cysticercs larvae of Taenia solium. Treatment by praziquantel (Biltricide) was followed by an increase of antibodies rate, but it was not possible to appreciate the effectiveness of this therapy.

Adult↗

PubMedDate not supplied

[Cerebral cysticercosis. Apropos of a case treated with praziquantel].

The authors report a case of cerebral cysticercosis in a 17 year-old adolescent. Partial seizures and moderate functional signs of intracranial hypertension were the presenting symptoms. Treatment with Praziquantel under corticosteroid therapy was successful with almost complete disappearance of radiologic abnormalities on the computerised tomographic examination performed 7 months after the end of treatment.

Adolescent↗

PubMed1985

Immunodiagnosis of cysticercosis: standardization of ELISA and its application to field conditions.

A standardization procedure for the enzyme-linked immunosorbent assay (ELISA) is described. Results were expressed as antibody units (ABU) which represent a multiple of absorbance of the negative control. The method was applied to immunodiagnosis of cysticercosis by IgG antibody determination. Different incubation temperatures had no substantial effect on results. There was a fair correlation between results obtained under field conditions in Cajamarca/Peru and results obtained under optimal laboratory conditions in Hamburg/FRG. Activity of antigen that had been lyophilized and stored under vacuum at ambient temperature was similar to the activity of antigen that had been stored frozen. There was a considerable loss of activity when antigen had been adsorbed to microtitre plates which were then stored in evacuated plastic bags at room temperature. Reproducible results were obtained both under optimal laboratory conditions and in the field.

Adsorption↗

PubMed1979

Intravitreal and intracameral cysticercosis.

A 49-year-old Mexican male presented with a free-floating cyst in the vitreous. The cyst was removed at the time of cataract surgery and on the first postoperative day a second cyst was found in the anterior chamber. The second cyst was excised by cryoextraction 6 weeks after the initial surgery, but the eye developed an inoperable retinal detachment and phthisis bulbi. Although the diagnosis of cysticercosis was made clinically, initially, the only laboratory evidence for parasitic infection was a peripheral blood eosinophilia. The patient later developed an enlarged liver which was consistent with parasitic infection based on a liver scan. The morphology and life cycle of the parasite is described as well as suggestions for surgical removal.

Anterior Chamber↗

PubMed1977

Observations on the application of counterimmunoelectrophoresis for the seroepidemiology of human cysticercosis.

An immunoepidemiological survey for cysticercosis was carried out in an endemic focus of Irian Jaya by use of a counterimmunoelectrophoresis (CIEP) technique. All individuals with palpable subcutaneous cysticerci were serologically positive by this technique as were 77.3% of the individuals giving a history of epileptiform seizures and 22.5% with no clinical complaints. The possible application of CIEP for epidemiological surveillance is discussed.

Adolescent↗

PubMed1977

An investigation on taeniasis and cysticercosis in Bali.

A survey was carried out in 3 villages in Bali to determine the prevalence of taeniasis in humans and cysticercosis in pigs. A total of 548 people were examined and Taenia sp. eggs were found in the faeces of 11. Four individuals passed proglottids; two T. solium and two T. saginata and three of these people also passed eggs in the faeces. A total of 12 or 2.2% were infected. Three pigs from a slaughterhouse were found heavily infected with Cysticercus cellulosae. Socio-ecological data indicate infections to be more common in people who eat raw meat dishes than those who eat fish. Poor sanitary conditions and the easy access of pigs to human faeces perpetuate the infection.

Adult↗

PubMed1983

[Late epilepsy in cerebral cysticercosis. 2 cases confirmed by tomodensitometry].

Invasion of the central nervous system by the larvae of Tenia Solium classically leads to severe illness. In some instances, however, the course is protracted and benign. The authors report on two patients with cysticercosis cerebri, revealed by delayed seizures without cerebral hypertension or any other manifestation. Computerized tomography established the diagnosis by demonstrating calcifications disseminated throughout the cerebral parenchyma. Such calcifications result from encapsulation of dead larvae. The possible diversity of the anatomic lesions caused directly or indirectly by the parasite explains why clinical manifestations are polymorphic. Diagnostic procedures are discussed.

Adult↗

PubMed1983

Cysticercosis of the nervous system.

In most Western countries cysticercosis is a rare disease and may at times cause serious diagnostic difficulties, but in South Africa, parts of India, Eastern Europe and South America it is fairly common and frequently features in differential diagnosis in its varying clinical forms. With the advent of computed tomography, diagnosis of the disease, particularly the asymptomatic forms, has become more frequent. As in other parts of the world, the true incidence of this disease in South Africa is unknown, as many more cases are encountered than are recorded and asymptomatic infestation is common. There is great regional variation, depending on pig-breeding, local customs and public health measures.

Cysticercosis↗

PubMed1984

Cysticercosis update.

Already the most common brain parasite disease, cysticercosis has been increasingly seen throughout the American Southwest. Symptoms arise from infection with larvae of Taenia solium, the pork tapeworm. Seizures, hydrocephalus, focal deficits and chronic meningitis most commonly result. Cerebrospinal fluid eosinophilia, serology by indirect hemagglutination and computed tomography are helpful adjuncts to diagnosis. New evidence suggests that selective immunosuppression is important for the parasites' survival and that cyst death permits renewed host immunity, which may actually precipitate an acute neurologic presentation. New larvicides, including praziquantel, are being tested in humans; caution is indicated in assessing these drugs because of the acute worsening associated with cyst death. Conventional therapy includes anticonvulsants, steroids or ventricular drainage as needed. Prevention remains the best management. Person-to-person transmission within the United States has recently been documented and merits public health scrutiny.

Anticonvulsants↗

PubMed1984

[Computed tomography in the diagnosis of cerebral cysticercosis].

Cerebral cysticercosis was diagnosed in 16 patients by CT, both before and after contrast injection. In six patients the findings were confirmed at operation and histologically. In ten patients, the diagnosis was supported by typical findings on conventional radiographs of the thighs, calves and skull. The CT findings permitted classification of the patients into three types of disease.

Adolescent↗

PubMed1978

[Cysticercosis of the brain].

Cysticercosis, a chronic helminthic disease rarely diagnosed during the patients' life is found in the practice of pathoanatomists. The paper presents two observations in one of which cystic and branching forms of the disease were combined.

Adult↗

PubMed1984

[Pure spinal cysticercosis. Note on the cerebrospinal fluid].

A patient from Benin experienced bilateral sciatic pain, followed by a progressive sensori-motor defect of the lower limbs. Five years after, he displayed symptoms and signs of a thoracic spinal cord compression, but no definite level could be determined. Myelography showed numerous intrathecal cysts from the cauda equina to the cervical cord. The diagnosis of cysticercosis was made by examination of the cysts removed after lumbar laminectomy. The search for another localisation of the parasite was negative. Repeated examination of cerebrospinal fluid (CSF) showed the presence of eosinophils, a high protein concentration, and a local synthesis of immunoglobulin G with an oligoclonal profile on electrophoresis. An accidental cyst punction revealed a fluid with protein migration in the alpha, beta and gamma ranges and a local synthesis of immunoglobulin A. Treatment with Praziquantel was uneffective.

Cysticercosis↗

PubMed1983

Uncommon manifestation of human cysticercosis with muscular pseudohypertrophy.

A case of human cysticercosis presenting with symmetric painless enlargement of muscles and seizures is presented. The patient had multiple subcutaneous nodules but no features of raised intracranial pressure. Muscle biopsy revealed densely packed cysticerci in calf muscles. Subcutaneous nodule biopsy was also confirmatory. So far sixteen cases have been described in the world literature and only one from outside India.

Adult↗

PubMed1983

[Cerebral cysticercosis in the computer tomogram].

Cysticercosis cerebralis can occur as a parenchymatous, subarachnoidal, ventricular or mixed type. One further form can be identified besides these clearly defined types. X-ray morphology in the computer tomogram, as well as the histopathological findings, suggest that this special form may be designated as "vasculitis cysticercotica" or "encephalopathia inflammatorica cysticercotia". Our own results indicate that this disease is widespread among the populations in developing and threshold countries; in our own patient material (Northern Mexico), the rate of incidence was more than 9%.

Brain Diseases↗

PubMed1983

Pathology of CNS cysticercosis.

The pathology of CNS cysticercosis is dependent upon the route of infection, the larval form, its predilection for certain anatomic sites, and the host reaction. Clinicopathologic correlates are illustrated.

Central Nervous System↗

PubMed1984

[Cerebral cysticercosis. A report on the treatment with praziquantel].

In the course of cerebral cysticercosis our patient suffered from severe headaches due to cerebral pressure raise and focal seizures. Diagnosis was assessed by computed tomography only. Serological confirmation followed later. By treatment with praziquantel there was an essential improvement of seizure frequency and headaches. A CT-control after treatment showed a reduction of cyst volume. These findings are discussed as to their clinical significance.

Antibodies↗

PubMed1981

[Diagnosis of experimental bovine cysticercosis using the ELISA test].

Seven calves of the Bohemian Spotted and Black-Pied Lowland breeds, aged two to three months and a half, were experimentally invaded per os with 5 000, 10 000, 25 000, 70 000, 95 000, 113 000 and 120 000 eggs of Taenia saginata. In the calf invaded with 70 000 eggs, antibodies were detected by the ELISA method already a week from invasion and in the remaining calves two to three weeks from invasion. The increase in the content of antibodies in the blood serum of the invaded animals was statistically significant from the fourth to the tenth week from invasion when the titre was 1 : 160 to 1 : 320 and when the measured extinction values ranged from 0.53 to 0.58. The antibody level remained significant and positive for seven months and a half to nine months. Clinical symptoms were observed in the calves invaded with 25 000 to 120 000 eggs for a period of 7 to 20 days from the 10th to 11th or 19th day after invasion. In the remaining calves the clinical symptoms were not significant. The post-mortal examination of four calves showed 2.1 to 3.9% of cysticerci from the applied eggs. The ELISA enzymatically immunological method, which was used for the first time in the Czech Socialist Republic in the case of cysticercosis, is suitable for detecting antibodies to the parasite Cysticercus bovis in the blood serum of calves experimentally invaded with the eggs of the tapeworm Taenia saginata.

Animals↗