Autism caused by dental amalgam?
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The mercury concentrations in blood (HgB) and urine (HgU) samples, and in exhaled air (HgAir) were measured in 147 individuals from an urban Norwegian population, using cold vapour atomic absorption spectrometry. The study aimed to estimate the mercury exposure from the dental restorations, by correlating the data to the presence of amalgam restorations. Mean values were HgB = 24.8 nmol/l, HgU = 17.5 nmol/l and HgAir = 0.8 micrograms/m3. HgU correlated with HgAir, and both HgU and HgAir with the number of amalgam restorations, amalgam restored surfaces and amalgam restored occlusal surfaces. HgB showed poor correlation to HgU and HgAir and the presence of amalgam restorations. A differentiation of the mercury absorption due to exposure from dental amalgams and from the dietary intake, necessitates measurements of both organic and inorganic mercury in the plasma, and in the erythrocytes. The results suggest that individuals with many amalgam restorations, i.e., more than 36 restored surfaces, absorb 10-12 micrograms Hg/day.
OBJECTIVE: To study the association between allergic diseases (eczema, allergic rhino-conjunctivitis, and asthma) and different types of dental restorative materials (amalgam, composite, and glass ionomer) in Swedish schoolchildren. DESIGN: Cross-sectional survey with a questionnaire asking for symptoms of allergic disease during the previous year. This information was combined with current dental status (number and type of filled tooth surfaces). SETTING: Primary care and a school in the centre of a middle-sized Swedish town (approx. 80,000 inhabitants). PARTICIPANTS: 348 pupils of both sexes 13-15 years old. OUTCOME MEASURES: The occurrence of allergic disease in pupils with and without dental fillings of different types. The mean number and type of filled tooth surfaces in diseased and healthy pupils. RESULTS: 44% of the pupils had no amalgam fillings. This group of children reported significantly more often asthmatic symptoms than the group with amalgam (P = 0.02). The asthmatic children had a lower mean number of amalgam surfaces than the other pupils (P = 0.002) and also a lower mean number of filled tooth surfaces of all types. CONCLUSION: The results of this study do not support the theory that amalgam fillings increase the prevalence of allergic diseases or allergic reactivity as such in schoolchildren. Neither do composite and glass ionomer seem to cause such complications.
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