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Influence of disorders of visual perception in word-to-picture matching tasks in patients with Alzheimer's disease.

Patients affected by early Alzheimer's disease were given word-to-picture matching tasks in which the foils shared lexical-semantic, phonological, or visual-perceptual features with the target. The aim of the study was to evaluate the influence of the visual perceptual deficit in lexical comprehension tasks based on pictorial material. The results demonstrated that perceptual deficits are common in Alzheimer's disease. This finding is in agreement with the hypothesis that multiple modular deficits in Alzheimer's disease contribute to impaired comprehension.

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Visual perception and aging.

A series of studies performed in our laboratory on aging and its effect on perceptual processing and working memory capacity for visual stimuli are reviewed. Specifically, studies on luminance, colour, motion, texture, and symmetry processing are reported. Furthermore, experiments on the capacity to retain size and spatial frequency information are also discussed. The general conclusion is that there are a number of perceptual abilities that diminish with age. However, the extent of these deficits will depend on the complexity of the neural circuitry involved for processing a given task. This is also true for visual working memory where no evidence of loss due to aging is demonstrated for processing low-level visual information, when individual differences in sensory input are compensated for. It is concluded that perceptual processing deficits due to aging (like working memory) will become evident when the computational load reaches a certain level of complexity (larger or more complex network) even if the tasks remain cognitively simple.

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