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[Femoral reconstruction with endosteal bone allografts protected by a metallic mesh in reoperation of total hip prosthesis. 19 cases with an average follow-up of 83 months].

PURPOSE OF THE STUDY: To assess after 83 months of follow-up, the results of 19 femoral revisions carried out according to an original method combining a cemented stem and bone reconstruction by means of impacted-morcelized bone allograft protected by a titanium mesh. MATERIALS: Twenty hips (18 patients mean aged 58 at surgery) were included between 1986 and 1991. Five hips had a least one previous prosthetic revision, one hip was revised because of septic loosening. No patient was lost for follow-up, but two had died during the follow-up period: one patient died one month after surgery was excluded, one other died 7 years after the index procedure and was included with his last hip rating. Loss of femoral bone stock was severe according to the SOFCOT four stage rating system: 2 femurs were grade II, 14 grade III, and 3 grade IV. Femoral stem migration was assessed with landmarks recommended by Walker. All the measurements were performed with a digitizer (OrthoGraphics). METHODS: All the procedures were carried out through a posterolateral approach, augmented by 4 trochanteric osteotomies and 5 distal femoral windows. After prosthesis and cement removal, a bone plug was placed into the medullary canal. Then, cancelous bone morcelized allografts were impacted in the femoral defects through the medullary canal. A titanium mesh cylinder was placed into the femur to separate the graft from the cement introduced later to obtain fixation of the revision stem. The stem was extended about 5 centimeters over the distal edge of the grafts in order to bridge the femoral defects. The mesh was extended only in front of the grafts and was used to protect them from excessive cement penetration. RESULTS: Functional improvement was noticeable since the Merle d'Aubigné Hip score improved from 9.8 to 16.3 at follow-up. The pain score improved from 2.1 to 5.5 and walking score from 2.3 to 5. Adverse effects occurred during the first cases and were related to cement removal: 3 greater trochanter fractures, 5 distal femoral perforations and 2 non displaced femoral shaft fractures. The septic revision had recurrence of infection associated with radiolucent lines > 2 millimeters and the only one graft resorption. One trochanteric non-union was observed but no prosthetic dislocation. Only one femoral stem migration (4.4 millimeters) was detected without any other radiographic features of loosening after 9 years of follow-up. This stem was considered as loosed, but was not revised because of few clinical symptoms. Only 2 radiolucent lines less than 2 millimeters at the bone cement interface in Gruen's zones 3 to 5. Likewise, no radiographic feature of stress-shielding was observed. On follow-up X-rays, 3 hips had corticalisation of the grafts, and 12 hips demonstrated normal cancelous trabeculations in the grafts. CONCLUSION: Satisfactory functional and radiographic results were obtained with this method after 5 to 10 years of follow-up instead of severe preoperative femoral bone stock impairement. Likewise, we observed only one recurrence of loosening diagnosed with the help of digitized X-ray examination. Only one significant (> 3.5 mm) femoral stem migration was detected. Radiographic features of femoral reconstruction were observed but without histologic proof of graft integration. This method uses a longer stem than the "Exeter", but avoids a high rate of femoral stem migration and appears compatible with femoral bone reconstruction.

Adult↗

[Coagulation abnormalities after total hip prosthesis (THP), a rare cause: antibiotic prophylaxis].

A 87-year-old patient developed coagulation abnormality following hip surgery related to the prophylactic use of cefamandole. Cefamandole as others cephalosporins with a methyl-tetrazol-thiol lateral chain interferes with the vitamin K regeneration cycle as do oral anticoagulants. Therefore, the use of others antibiotics or systematic vitamin K1 supplementation or single dose of cefamandole is recommended for patients with renal failure or with malnutrition. Vitamin K1 supplementation is a simple method resulting in complete resolution of the coagulation disorder.

Aged↗

[Mechanisms of the optimization of oxygen metabolism under the effects of mafusol and mildronate during emergency implantation of hip prosthesis].

The results of using antihypoxants Mafusol and Mildronate in the course of emergency endoprosthesis of the hip joint were analyzed in 41 patients at the age of (80.5 +/- 5.6) years with fractures of the proximal part of the femoral bone. The authors noted optimization of the organism oxygen budget under the influence of the drugs, its physiological mechanisms being deciphered. The protective properties of these drugs manifested themselves in lower consumption of oxygen by the tissues with greater possibilities of its release by oxyhemoglobin as well as in the lessening of intrapulmonary shunting and prevention of the development of metabolic acidosis.

Acid-Base Equilibrium↗

[Bilateral total hip prosthesis replacement in a single procedure].

This paper is a case report of a patient with bilateral hip dysplasia, bilateral secondary degenerative changes, adduction contracture and serious walking difficulties. The patient has undergone one-stage bilateral hip replacement. This procedure is advantageous because of fast recovery, fewer complications and rehabilitation easier than in the routine operation of two-stage bilateral total hip replacement.

Adult↗

Relationship of relapsing hip prosthesis infection by Staphylococcus aureus with gamma interferon deficiency.

Infections complicate 0.5 to 1% of surgeries for total hip prostheses. Staphylococcus species are the most common etiological agents. The role of host factors in the persistence of such infections despite appropriate therapy has yet to be determined. We report the defective immune response characterized by oversecretion of tumor necrosis factor and interleukin 10 and by undersecretion of gamma interferon in such a patient. Further study may determine the prevalence of such deficits and the most appropriate therapy for these patients.

Arthroplasty, Replacement, Hip↗

[Change in the CCD angle and the femoral anteversion angle by hip prosthesis implantation].

PURPOSE: The aim of the present study was to measure and interpret the change of the collodiaphyseal (CCD) angle and femoral anteversion after total hip replacement. METHODS: We prospectively examined 52 patients with coxarthrosis, who were treated by total hip replacement. Preoperatively and postoperatively we used a standard X-ray ap view to measure the CCD angle and computerized tomography to determine the femoral anteversion. These projected angles were converted into the real angles by using the method of König and Schult. RESULTS: On average the preoperative real CCD angle was 128 degrees (+/- 8.9 degrees) and the postoperative angle 145 degrees (+/- 4.8 degrees), preoperatively the real femoral anteversion angle was 14.1 degrees (+/- 6.9 degrees) and postoperatively 10.8 degrees (+/- 6.2 degrees). CONCLUSIONS: The effect of the postoperative valgisation can be explained by the given CCD angle of the used femoral stem prosthesis of 140 degrees (cemented Weller II stem) and 145 degrees (cementless CLS classic stem). It is possible that due to the valgisation and the decreased offset of the femoral stem prosthesis compared to the preoperative conditions the gluteal muscles are insufficient and overloaded. It is also known that the change of the femoral anteversion from the physiological conditions causes an increase of the torsional moment. The resulting increased interface load could possibly be a reason for loosening of the femoral stem. The conclusion can be drawn that the CCD angle and the femoral anteversion should more carefully be considered by the surgeon in total hip replacement. This could be reached by an exact implantation technique and the choice of the appropriate stem prosthesis with different CCD angles.

Adult↗

Mechanical consequences of bone ingrowth in a hip prosthesis inserted without cement.

Long-term biomechanical problems associated with the use of sintered porous coating on prosthetic femoral stems inserted without cement include proximal loss of bone and a risk of fatigue fracture of the prosthesis. We sought to identify groups of patients in whom these problems are accentuated and in whom the use of porous coating may thus jeopardize the success of the arthroplasty. We attempted to develop clinical guidelines for the use of sintered porous coating by investigating the long-term biomechanical effects of bone growth into partially (two-thirds) porous-coated anatomic medullary locking hip prostheses that fit well. More specifically, we used a detailed finite element analysis and a composite beam theory to determine the dependence of proximal loading of the bone and maximum stresses on the stem on the development of clinically observed patterns of bone ingrowth and the dependence of the risk of fatigue fracture of the stem on the diameter of the stem, the diameter of the periosteal bone, and the material from which the prosthesis was made. We found that bone ingrowth per se substantially reduced proximal loading of the bone. With typical bone ingrowth, axial and torsional loads acting on the proximal end of the bone were reduced aa much as twofold compared with when there was no ingrowth; bending loads on the proximal end of the bone were also reduced. The risk of fatigue fracture of the stem was insensitive to the development of bone ingrowth. However, the risk of fatigue fracture of the stem increased with decreased diameters of the stem and the periosteal bone and with increased modulus of the stem. The maximum risk of fracture was found in active patients in whom a cobalt-chromium-alloy stem with a small diameter had been implanted in a bone with a small diameter.

Biomechanical Phenomena↗