PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “Pattern Recognition, Visual”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 775 records · Page 43Linked to original sources

Objective measurement of contrast sensitivity using the steady-state visual evoked potential.

Contrast sensitivity functions (CSFs) were determined electrophysiologically with the steady-state visual evoked potential (VEP). Psychophysical CSFs obtained by the method of increasing contrasts were also measured concurrently with the VEP trials. The VEP contrast thresholds were obtained using a rapid recording technique in which the contrast of a counterphase sinewave modulated at a temporal frequency of 7.5 Hz was swept from 0.5% to 40% over a period of 22 s in 39 equal logarithmic steps. For this pattern reversal stimulus, the amplitude and phase of the second harmonic response as a function of contrast were measured using a discrete Fourier transform (DFT). Contrast sensitivities at five spatial frequencies ranging from 0.5 to 14.9 cpd were measured. The VEP contrast thresholds were determined by a linear extrapolation to zero amplitude. The contrast threshold obtained by the two methods correlated at 0.816 for 14 subjects. For all five spatial frequencies there were no significant differences between the contrast sensitivities derived from the two methods.

Adult↗

Retinocortical conduction time in diabetics with abnormal pattern reversal electroretinograms and visual evoked potentials.

Clinically evident retinal vascular disease in patients with diabetes mellitus may be preceded by an increase in visual evoked potential latency in electrophysiologic testing. This increase may indicate either retinal or optic nerve dysfunction. To determine the origin of the latency increase we initiated a cross-sectional study of simultaneous pattern-reversal electroretinograms and visual evoked potentials. We recorded transient (3.8 reversals/second) pattern electroretinograms and visual evoked potentials using both 15' and 60' high-contrast black-white checks. Fifty-five diabetic patients (34 with no retinopathy and 21 with background retinopathy) and 34 age-matched visual normals (controls) were tested. Group data in diabetics showed significant latency increases in both tests, but not significant differences in retinocortical conduction time were noted. These results suggest that the increases in visual evoked potential latency exhibited by diabetic patients with little or no retinopathy usually reflect altered retinal function rather than optic neuropathy. Two patients with background retinopathy exhibited retinocortical conduction times that exceeded the normal mean by more than two standard deviations, suggesting that optic neuropathy may occasionally occur in diabetic patients with background retinopathy.

Adult↗

Accommodation power determined with transient pattern visual evoked cortical potentials in diabetes.

Changes of accommodation power by aging were measured with pattern reversal visual evoked cortical potentials (VECPs) in 45 normal subjects and 32 patients suffering from diabetes mellitus. Transient VECPs were recorded by increasing minus power lenses in front of the eye at one-diopter steps, up to the point where no VECP was recordable. It was found that the amplitude of the P100 component became attenuated linearly with increased accommodation stimulus. The regression line was calculated from the VECP amplitude vs. accommodation stimulus plots (in diopters) and the objective accommodation was determined by extrapolating the line to 0 microV amplitude. The measured accommodation power with pattern VECPs was attenuated significantly in the normal group over 40 years old and in diabetics, and also was found to be larger by approximately 2.5 diopters than that obtained subjectively by the near-point rule.

Accommodation, Ocular↗

The influence of age on the electroretinogram and visual evoked potential.

Changes in the ERG and VEP across the life span were investigated. The dark adapted and scotopic ERGs both showed a progressive increase in the implicit times of the A and B waves and a reduction in the amplitude of the AB configuration. There was also an increase in the implicit times of the oscillatory potentials of the photopic ERG. The flash and pattern onset-offset VEP both showed changes in waveform with age whilst the waveform of the pattern reversal VEP was constant. The amplitudes of the components of the flash and pattern reversal VEP were very high in the teenage group, but once reduced, were constant from the twenties onwards, showing no further consistent age changes. The latencies of the components of the pattern VEPs showed an increase with age which could be accounted for by the reduction in retinal illuminance due to the decrease in pupil diameter with age. However, the increase in the latency of the flash major positive (P2) component was greater than that expected from the decrease in retinal illuminance alone, suggesting that this is due to neural factors.

Adolescent↗

Pattern flash visual evoked potentials in patients with homonymous hemianopia.

Visual evoked potentials from seven horizontally spaced electrodes were recorded from normal subjects and subjects with homonymous hemianopia in response to hemifield pattern flash stimulation. Stimulation produced a large early peak that was positive on the scalp contralateral to the hemifield and negative on the ipsilateral scalp. From computer fitting of the amplitudes versus electrode position, the position of the equivalent source was found to be in the contralateral hemisphere. The horizontal orientation of the dipole source was approximately tangential (parallel) to the occipital scalp surface with negative polarity toward the medial fissure. In normal subjects, visual evoked potential amplitudes at the first peak were positive on the left and negative on the right for right hemifield stimulation. Left hemifield stimulation showed the opposite results. Three patients with homonymous hemianopia showed normal visual evoked potential results from their functional hemifields and nearly flat results from their hemianopic hemifields. The normal visual evoked potentials originated in their intact cortical hemispheres.

Adult↗

The effects of age on steady-state pattern electroretinograms and visual evoked potentials.

Steady-state pattern-reversal electroretinograms and visual evoked potentials were simultaneously recorded in two groups of young and elderly normal volunteers. The young group consisted of 23 subjects (13 women and 10 men) aged 18 to 28 years, and the elderly group consisted of 24 subjects (11 women and 13 men) aged 58 to 77 years. Stimuli were square-wave gratings ranging in spatial frequency from 0.5 to 6 c/deg and phase reversed at a frequency of 4 Hz. Pattern-reversal electroretinograms and visual evoked potentials consisted of a prominent second and a smaller fourth harmonic response. Spatial frequency-amplitude functions of the pattern-reversal electroretinogram second and fourth harmonics were similar for the young and elderly groups. The mean fourth harmonic phase was significantly shifted in elderly subjects compared with young subjects for all spatial frequencies tested. Spatial frequency tuning was observed for amplitude and phase functions of the visual evoked potential second and fourth harmonic responses for both age groups. Age had a significant effect on phase for spatial frequencies above 1.5 c/deg. Amplitude of the fourth harmonic was significantly lower for the elderly group at 1.5-4 c/deg. Phase was significantly different between groups for spatial frequencies below 3 c/deg. Our results suggest that aging influences both retinal and central visual pathways. Aging differentially affected the visual evoked potential second and fourth harmonic responses, suggesting different neuronal origins for these components.

Adolescent↗

Albino-type misrouting of the optic nerve fibers not found in dissociated vertical deviation.

It has been suggested that albinolike misrouting of the visual pathway occurs in patients with dissociated vertical deviation (DVD). We re-examined this contention in ten DVD patients using visually evoked potentials. Full-field monocular pattern-onset checkerboard stimulation was employed. The visually evoked potentials were recorded simultaneously from both occipital lobes. Their differential activity during stimulation of the right eye was compared with that obtained during stimulation of the left. We found no predominance of crossed projection in any of the DVD cases. The results in nine normal subjects were similar. In 13 albino patients, however, there was a relative positivity in the contralateral hemisphere about 100 ms after pattern-onset, which reconfirmed predominance of the crossed projection. Possible artifacts are discussed that may have led to the assumption of misrouting in DVD in two previous reports.

Adolescent↗

Areal influences on complex cells in cat striate cortex: stimulus-specificity of width and length summation.

In single neurones recorded from the striate cortex of cats anaesthetized with N2O/O2/halothane, receptive field dimensions, length specificity and areal extent of drive were assessed for different classes of visual stimuli. Receptive fields were mapped as rectangular minimum response fields (MRFs). Spatial summation along the axis of preferred orientation was assessed: for moving bars whose length was varied (length summation); and for height variation of a square-wave grating patch against a uniform grey background, or a patch of moving texture against a stationary background of similar texture. In complementary tests a moving square-wave grating background was progressively occluded by a uniform grey foreground mask of variable height; or a mask of stationary texture of variable height progressively occluded a background of moving texture. In parallel measurements, the width of grating or textured patches or masks was varied whilst maintaining height constant. Broadly speaking, the areal influence of each class of stimulus was comparable, and distinct from extra-receptive field phenomena in evoking responses from within the receptive field, but not from surrounding areas. The masking paradigm provided the most sensitive measure of receptive field height and width. However, in some neurones length summation, the degree of end-stopping, and the directional bias depended critically on the stimulus configuration used. Length summation tended to be more dramatic for short bars than for gratings. Length summation for texture was significantly more pronounced than for an oriented bar in special and in intermediate complex neurones. By contrast, endstopping was typically less intense for gratings than for bars, and least pronounced for texture. Because of stimulus specificity, complex neurones assigned to particular functional subgroups on the basis of their response to oriented bars may exhibit quite different patterns of behaviour for other classes of stimuli.

Animals↗

Simple methods of identifying the independently generated components of scalp-recorded responses evoked by stationary patterns.

The preceding study of the influence of various stimulus parameters on a single subject's pattern-on-set visual evoked potentials (VEPs) identified several constituent potentials with distinctive stimulus-related (and topographic) response properties. This paper describes related experiments in which an appropriate selection of the stimuli used in the original study, and some additional images of faces and other figures, were used to analyse and compare the composition of the VEPs recorded from 49 subjects. The results showed: (1) that the previously discovered response components were again easily identified: the early negative and late negative potentials, for example, were distinguishable in most subjects, not only by their different latencies and surface distributions, but also by the former's preferential, or more often selective, evocation by patterns of discrete elements compared with gratings, and the latter's selective enhancement by patterns containing monocular depth cues; (2) that there was considerable inter-individual variation in the relative sizes (as well as changes in latencies) of the basic components; (3) all the components were not always discernible in each individual's VEPs, and none was recorded for all 49 subjects; and (4) that because of these component amplitude variations, which were the main cause of variable overall response waveforms, there was no simple relationship between the VEP peaks and underlying components. Some important methodological implications of these findings are discussed.

Adolescent↗

A face-responsive potential recorded from the human scalp.

Evoked potentials were recorded to the separate tachistoscopic presentation of a variety of faces and other simple and complex visual stimuli. A positive potential of 150-200 ms peak latency which responds preferentially, but not exclusively, to faces was identified in 8 out of 9 subjects. This potential, best recorded from midline central and parietal electrodes, was evoked by all face stimuli, including photographs, outline drawings, and fragmentary figures. Changes in stimulus size and other parameters which do not affect the clarity of the face, generally had little effect on the peak amplitude. Stimulus changes such as face inversion, reversing the contrast polarity of photographic images, and selectively removing particular facial features, produced a marked increase in latency but often only slight attenuation of this peak. These response properties correspond well with those reported for face-related single cells in the temporal cortex of the rhesus monkey. The scalp distribution of this face-responsive peak also appears consistent with bilateral sources in the temporal cortex.

Evoked Potentials, Visual↗

The visually evoked potential in humans with amblyopia: pseudorandom modulation of uniform field and sine-wave gratings.

The visually evoked potential was recorded in response to pseudorandom modulation of a uniform field and sine-wave gratings in humans with naturally occurring amblyopia. Analysis in the frequency domain showed similar temporal tuning when the nonamblyopic and amblyopic eye were stimulated with a uniform field and with spatial stimuli. Although most observers showed some reduction in the cortical response to stimulation of the amblyopic eye with uniform field modulation, all observers showed reductions in the response obtained for stimulation of the amblyopic eye with spatial stimuli. This decrease in the cortical response to stimulation of the amblyopic eye for sine-wave gratings was present at either the low and middle temporal frequencies or over the range of temporal frequencies tested, and was greater than that observed in those amblyopes who also showed reductions with uniform field modulation. Latency measures in the time domain showed increases in the response of the early components when the amblyopic eye was stimulated with a uniform field and with sine-wave gratings above 2 c/deg. These electrophysiological results confirm the results obtained psychophysically which suggest that although amblyopia is primarily a spatial anomaly, the response is influenced by the temporal attributes of the stimulus as well.

Adolescent↗

A biologically motivated and analytically soluble model of collective oscillations in the cortex. II. Application to binding and pattern segmentation.

Feature linking and pattern separation are shown to be performed as simultaneous processes by a highly connected auto-associative network of spiking neurons (spike response model). In principle, many (e.g., with nine) patterns can be separated, but with a biological set of parameters the number is limited to four. The patterns have been learned by an asymmetric hebbian rule that can handle a low activity which may vary from pattern to pattern (in a range between 4% and 7%). Spikes are generated by a threshold process and--with some delay--transmitted to postsynaptic neurons. There they evoke an excitatory or inhibitory postsynaptic potential (EPSP or IPSP). Spike emission is followed by an absolute refractory period (1 ms) and activates an inhibitory delay loop that prevents continuous firing. Three different network topologies are discussed, i.e., a structureless fully connected system, a network composed of two 'hemispheres', and finally a hierarchical network with four subsystems that represent different 'functions' and interact via feedforward and feedback connections. Functional feedback turns out to be essential for context-sensitive binding. The coherence between the two hemispheres is dependent on the interhemispheric delays. If these are on average too large, the two hemispheres oscillate coherently by themselves but phase-shifted by half a period with respect to each other.

Animals↗

Considerable deficits in the detection performance of the cat after lesion of the suprasylvian visual cortex.

The ability of two cats to discriminate between two geometrical outline patterns in the presence of superimposed structured background was tested before and after bilateral removal of the lateral suprasylvian visual areas (PMLS, PLLS, AMLS, ALLS, part of area 7). There were mild deficits when patterns and background were kept stationary; these deficits may be due to a partial undercutting of areas 17, 18 and 19. However, there was a severe impairment in performance when the patterns were moving on a stationary background which may be due to loss of the suprasylvian visual areas. Movement of the background relative to the figure resulted in an intermediate detection deficit.

Animals↗

Pseudorandom binary sequence stimulation applied to the visual evoked response. Normative data and a comparative study with pattern and flash stimulation.

The investigation of patients who are unable to fixate the pattern visual stimulus generally requires the use of diffuse flash stimulation to elicit the visual evoked response. However, by comparison with pattern, flash stimulation has proved relatively insensitive in identifying lesions of the visual pathway. We investigated a more complex method of flash stimulation. A pseudorandom binary sequence has been used to generate the diffuse visual evoked response stimulus. The pseudorandom binary sequence, rather than producing a single flash, switches in a pseudorandom fashion between two levels of illumination. The result is a diffuse visual stimulus approximating band-limited white noise. The series is periodic, enabling signal averaging to be performed. By applying the methods of random signal analysis, the impulse or transient response of the visual pathway can be determined. Our normal pseudo-random binary sequence visual evoked response impulse function, derived from 29 normal subjects, had the morphologic characteristics of the conventional flash visual evoked response and a major positive component (P100), whose latency mean and standard deviation closely matched that of our normative pattern visual evoked response. However, the P100 amplitude standard deviation was significantly greater than that produced by conventional pattern and flash stimulation. We investigated 140 patients by means of pattern, flash and pseudorandom binary sequence stimulation. The pseudorandom binary sequence visual evoked response proved to be almost 12 times more effective than flash visual evoked response in detecting lesions of the visual system.

Adolescent↗

Visual responses in the temporal cortex to moving objects with invariant contours.

We were interested in how the visual attributes of motion and shape are integrated in the temporal cortex of monkeys. We recorded neural activity in the middle portion of the superior temporal sulcus (STS) of monkeys during a sequential visual discrimination task while the animals maintained fixation. We used images of objects with invariant outlines rotating in 3D space either clockwise or counterclockwise as visual stimuli. In the sequential discrimination task, after the fixation pattern was presented for 1.0 s, the sample stimulus (S1) appeared at the center of the monitor screen for 0.8 s. After a delay period of 0.5-2.0 s, the same stimulus or a new response stimulus appeared on the screen for 0.8 s. In each block, the response stimulus was either a new direction of rotation or a new shape. Of 425 responding neurons isolated in the STS, 202 (48%) showed significant activity when S1 stimuli were presented. Of these visual neurons, 27 (13%) were categorized as motion and shape selective (MS), 69 (34%) as shape selective (S), and 6 (3%) as motion selective (M). Briefer than for MS or S neurons, the latency of the remaining non-selective neurons was 80 ms. Latencies of visual response (110 ms) of both MS and S neurons were similar. On the other hand, MS neurons started responding later (180 ms) to changes in direction. Our findings show that neurons in the STS, responding selectively to changes in shape, do respond to relatively simple motion and that variable contouring is not essential to elicit motion response. The results may also suggest the functional segregation of selective versus non-selective neurons and the later arrival of directional response to MS neurons in the STS.

Action Potentials↗

Motion adaptation: net duration matters, not continuousness.

Motion processing is strongly adaptable. Adaptation strength generally increases with motion duration. Little is known, though, about the effect of motion onsets and offsets, which might be relevant if adaptation is not based on motion duration per se, but on the recent cumulated activity of motion-processing mechanisms. Thus, we presented intermittent motion with three different onset rates for adaptation. The duty cycle was kept constant at 33% while the rate of motion onsets was either 1.4, 2.8, or 5.6 per second. Stationary stimuli and continuous motion were used as reference conditions. The amplitude of the N2 component of human motion visual evoked potentials was used to quantify adaptation. All three onset rates induced virtually identical amounts of adaptation (occipitally, P=0.71; occipito-temporally, P=0.27), suggesting that the continuousness of the stimulus does not play an important role in motion adaptation. This was confirmed by measuring the motion aftereffect psychophysically.

Adaptation, Physiological↗