Clinical pharmacology services: a pharmacist-based consulting service for the developmentally disabled.
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Parents' and teachers' ratings of social skills and behavioural problems for 89 special education students aged 8 to 15 yr. were measured using the Social Skills Rating System of Gresham and Elliott. The sample was selected in a school for educable mentally retarded children in Shiraz, Iran. The low to moderate correlations between the two sets of ratings suggest that assessment of social skills and behavioural problems should include the use of different rating scales in more than one setting. Sex differences were not significant for parents' and teachers' ratings of these disabled children. The scores showed high internal consistency.
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Individual and maternal characteristics as potential risk factors for having severe mental retardation (SMR) occurring with and without cerebral palsy (CP), epilepsy, or a pervasive developmental disorder (PDD) were explored among a cohort of 119,404 children without Down syndrome born in the California Central Valley in 1992 and 1993. Unadjusted and adjusted relative risks (RRs) and their 95% confidence intervals (CIs) based on the Poisson distribution were used to estimate the risks associated with each individual and maternal factor studied for each SMR diagnostic category. The most notable increased risks for SMR occurring in isolation or with CP or epilepsy was for children born low-birth-weight or preterm who were at a substantially increased risk (RRs 2.6-9.9). In contrast, the risk of SMR occurring with a PDD was the greatest among males compared to females (RR = 3.4, 95% CI 1.5, 7.9), Blacks compared to Whites (RR = 5.1, 95% CI 1.7, 15.5), and Asians compared to Whites (RR = 3.9, 95% CI 1.3, 12.0). Etiologic heterogeneity when SMR occurs with a PDD was suggested.
This study compared behavioral presentation of toddlers with autistic spectrum disorders (ASD) and toddlers with global developmental delay (DD) or developmental language disorder (DLD) who display some characteristics of ASD using the diagnostic algorithm items from the Autism Diagnostic Observation Schedule, Generic (ADOS), the Childhood Autism Rating Scale (CARS), and Modified Checklist for Autism in Toddlers (M-CHAT). To date, 195 children have failed the M-CHAT and have been diagnosed with ASD, DD or DLD. Children with ASD had prominent and consistent impairments in socialization skills, especially joint attention skills and were more impaired in some aspects of communication, play, and sensory processing. Children with ASD and children with DD/DLD shared common features, but certain behavioral markers differentiated the two groups.
OBJECTIVE: We hypothesized that the Infant/Child Monitoring Questionnaire (ICMQ) could be used to identify at-risk infants eligible for developmental interventional services. STUDY DESIGN: Of this cross-sectional observational study, group A (n = 108) included a retrospective review of moderate risk infants scheduled for developmental assessment clinic (DAC) visits. Group B (n = 108) included moderate-risk infants whose parents completed the ICMQ. Group C (n = 67) included high-risk infants who were seen in the DAC and whose parents completed the ICMQ. RESULTS: For group A infants, 43.5% were seen in the DAC; 10.6% of these visits resulted in an intervention. For group B infants, 56.5% of parents completed the ICMQ; 66.7% of subsequent visits resulted in an intervention. For group C infants, comparison of ICMQ and DAC visits showed moderate agreement (kappa = 0.50). CONCLUSION: The ICMQ is a useful tool to identify moderate-risk infants requiring further intervention, but caution must be used when applied to high-risk infants.
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