[Delayed hypersensitivity reaction to capsular polysaccharides of Klebsiella pneumonia].
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Synovitis was produced in the rabbit knee by repeated intraarticular injection of a preparation of mediators of cellular immunity. The mediators were prepared by incubation of KLH with lymph node cells of animals previously immunized with KLH in Freund's adjuvant. Following three intraarticular injections, a chronic synovitis resulted in which hyperplasia of the lining layer and infiltration of the sublining layer occurred. The cell types in the sublining layer were predominantly histiocytes and fibroblasts. These experiments demonstrate that mediators of cellular immunity may produce a chronic inflammatory reaction when injected repeatedly into normal joints. They indicate that the cellular immune response may play a role in the development of the synovitis of immunologically induced arthritides.
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OBJECTIVES: The aim of this work was to assess cellular immunity using the multitest CMI and relate its results with lymphocyte CD4 counts, and the risk to developed active tuberculosis if the multi-test's tuberculosis pápula was positive. METHODS: Prospective longitudinal follow-up of 342 IDU patients, 210 infected with HIV-1 and seronegative 132 patients. The cohort study was 165 IDU HIV-1 positive patients (128 men, 37 female). Ages was 18 to 45 years. Study time were 25 months (8-25). Tuberculin skin tests and multitest IMC were performed at baseline and each three months, and screening from active tuberculosis were performed all study when necessary was considered. RESULTS: Actived tuberculosis developed in 9.25 cases per one hundred persons and year from follow-up in the ranges with better immunologic status (Score from PHR > 10 mm). There are an significative correlation between tuberculosis skin test diameter and PHR tuberculin fraction papula. CONCLUSIONS: PHR performed with Multitest IMC is an useful test to evaluate cellular immune system, and HIV-1 positive patients with energy in this test or positive tuberculine fraction must be considered to isoniazid (9 months) prophylaxis.
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Buccal mucosal allergies are rare because the conditions for sensitization are less favourable in the buccal environment. Clinical presentation is dominated by subjective manifestations (hardening, hypersialorrhea, "burning mouth" syndrome). Extradental etiologies are linked with cosmetic and medicinal topics, as well as dental etiologies caused by metals, alloys of mercury and resins.
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