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At least 793 records · Page 44Linked to original sources
PubMed1955

SUPPURATIVE lymphadenitis following intradermal BCG vaccination of preschool children.

Regional lymph-node abscesses often occur among infants and young children following BCG vaccination, and the purpose of this study was to find ways to avoid glandular complications, or at least minimize their frequency, without jeopardizing the success of vaccination.Over 1,700 children ranging in age from 6 months to 7 years were vaccinated by one of nine different procedures obtained by various combinations of two strengths of vaccine, two depths of injection, and three volumes of vaccine, in an attempt to reproduce, experimentally, some of the kinds of variation that may occur in practical programmes. Follow-up examinations were made at 10 weeks and at one year, the local and glandular responses being observed and measured and the degree of tuberculin sensitivity assessed by an intradermal 10 TU test.BOTH THE DOSE OF VACCINE AND THE AGE OF THE CHILD WERE FOUND TO HAVE A STRIKING EFFECT ON THE FREQUENCY AND SEVERITY OF LYMPHADENITIS: the larger the dose and the younger the child, the higher the frequency of enlarged or perforated axillary lymph nodes. Furthermore, there was a close association between the findings at the two follow-up periods: with only one exception, children with negligible enlargement of the nodes at the 10-week examination had negligible findings at one year, whereas all the children with enlarged and adherent nodes at 10 weeks had evidence of perforation at one year.THE SIZE OF THE VACCINAL LESION WAS ALSO AFFECTED BY VACCINE DOSE AND BY AGE OF CHILD: the lesion was larger in the younger children and with the stronger doses. The degree of tuberculin sensitivity was affected only slightly by the variations in dose and still less by the age of the child.The size of the wheal raised by intradermal injection of vaccine was found to vary with the age of the child and with the depth of injection as much as it varied with the volume of vaccine injected. There can be no doubt that gauging the dose by the size of the wheal, rather than by the calibrations on a non-leaking syringe, is a very inaccurate procedure. When the dose of vaccine can be accurately measured, a stronger vaccine can be given (and perhaps a stronger degree of immunity attained) without causing an intolerable frequency of suppurative lymphadenitis.

BCG Vaccine↗
PubMedDate not supplied

[Treatment of suppurative wounds in patients with diabetes mellitus by magnetic field and laser irradiation].

The efficacy of including a magnetic field, low-intensity laser beam, and their combination in the complex of therapeutic measures was studied in 119 patients with suppurative wounds and diabetes mellitus. With the use of magnetic field or laser beam intoxication diminished, the organism's immunological status was stabilized within a shorter time, the wound process followed a quicker course, and treatment took less time. The magnetic-laser effect has advantages over separate use of these factors.

Adult↗
PubMed2004

[Pseudoaneurysm of the left ventricle following suppurative pericarditis and sepsis due to Staphylococcus aureus: a case report].

A 35-year-old diabetic man presented with a left ventricular aneurysm very close to the mitral valve annulus. He had been conservatively treated for suppurative pericarditis and sepsis due to Staphylococcus aureus during the previous 3 weeks. The left ventricular aneurysm rapidly enlarged (6 cm in diameter) and the patient underwent emergent surgery. Cardiopulmonary bypass and cardioplegic arrest were induced, and the left ventricular aneurysm orifice was closed with a double layer of autologous pericardium. Mitral valve function was not impaired. He has been doing well for 4 years. Surgery is indicated as soon as possible after the diagnosis of infective left ventricular aneurysm.

Adult↗
PubMed1992

[Clinical features of acute obstructive suppurative cholangitis (AOSC) in the old age].

Nineteen cases (male 6, female 13) of acute obstructive suppurative cholangitis (AOSC) were divided into 2 groups and were studied, Group A; over 70 yrs old (12), Group B; under 70 yrs old (7). The most frequent etiology of AOSC was choledocholithiasis (Group A 75%, Group B 43%). Urgent biliary drainage was performed in 18 cases, and which were clinically improved. The decreasing rate of bilirubin were fair in both groups and only 2 cases in Group A were dead. Concerning with the laboratory findings on admission, Group A had a higher level of BUN than Group B, and there were no other significant differences. Complications were frequently occurred in Group A (Shock 83%, DIC 83%, Renal failure 42%). The diameter of choledochus at biliary drainage was below 9 mm in 45% of cases in Group A, which implied the rapid progression to AOSC from the onset of biliary obstruction. Early diagnosis and urgent biliary drainage were essential for the management of AOSC in the old age.

Acute Disease↗
PubMed1991

[Disorders of erythrocyte deformability in patients with acute suppurative-septic diseases of the lung and pleura].

In 163 patients with acute suppurations of lungs and pleura a substantial reduction of deformability of erythrocytes was established. The maximum increased rigidity of blood red cells was noted at the peak of the pyo-destructive process and postoperative period as well as in the complicated course of the postoperative period. The curative plasmapheresis, general hyperbaric oxygenation exert positive influence upon plastic properties of erythrocytes.

Acute Disease↗
PubMed2006

[Suppurative bacterial acute parotitis in adults. Clinic and microbiological findings in 10 admitted patients].

We report the clinic and microbiological findings that were obtained in 10 adult patients admitted by our ENT Service with diagnosis of suppurative bacterial acute parotitis. S. aureus and Streptococcus sp were the most isolated organisms. All the patients were treated by hidratation, endovenous antibiotic therapy sometimes modified according to the antibiogram results, analgesics and antiinflammatories with success. In 3 times it was necessary to drain the purulent collection and in one of them there was a retroauricular abscess secondary to sialoadenitis.

Acute Disease↗
PubMed1991

[The bacteriological and immunological assessment of peritoneal-enteral lavage in the treatment of general suppurative peritonitis at the stage of multiple organ failure].

The article shows that peritoneal-enteral lavage reduced the yield of microorganisms from the suppurative focus, the reduced yield after a single lavage might be considered as a favourable prognostic sign. Results of a quantitative bacteriological analysis are thought to be an objective criterion for performing or completing the stage of the peritoneal lavage. The peritoneal-enteral lavage promotes the activation of local defensive reactions in the abdominal cavity.

Adolescent↗
PubMed1991

[Spongy dressings from alginic acid salts in the treatment of suppurative wounds].

Spongy dressing materials made from alginic acid salts, specifically immobilized with terrilitinum (teralginum) were found to reduce the period of wound purification from suppurative and necrotic tissues and to facilitate more rapid, viz. 1.5-fold compared to the control, patient recovery, particularly after preliminary wound treatment with defocussed CO2 laser beam. In the group on teralginum, the cytological study demonstrated more intensive wound purification from microflora, more active growth and differentiation of reparation cells, specifically of fibroblasts, which influences the results of accelerated wound healing.

Alginates↗
PubMedDate not supplied

[Treatment in the rupture of suppurating hepatic echinococcosis into the abdominal cavity].

The rational surgical methods of treatment in 85 patients with suppurative hepatic echinococcosis penetrating into the abdomen cavity are presented. The own author's techniques strictly individualized in each case are described in details. The classification of the variants of the complications and their clinical features are given. The advantage of the presented surgical methods has been proved by a reduction in the period of treatment, the number of intraabdominal complications and mortality rate.

Adult↗
PubMedDate not supplied

[Hemofiltration in the adult respiratory distress syndrome in patients with diffuse suppurative peritonitis].

Hemofiltration (HF) potentials are presented in complex treatment of 12 patients with disseminated suppurative peritonitis in the phase of polyorgan failure with signs of adult respiratory distress syndrome (ARDS). It has been shown that HF reduces the amount of extravascular fluid in the lungs, increases right-to-left pulmonary shunt, eliminates mediators causing higher permeability of pulmonary vessels, and other medium-molecular toxins. Death was recorded in 6 out of 12 patients. In 3 of the dead patients HF had an obvious positive effect, and death was caused by acute hepatorenal failure. Thus, HF seems promising for the treatment of ARDS in patients with peritonitis.

Adolescent↗
PubMedDate not supplied

[Immune shifts and their correction in the extremely severe course of diffuse suppurative peritonitis in children].

Clinical and immunological studies of 65 patients with extremely severe disseminated suppurative peritonitis have revealed profound disturbances in their immune status. A considerable (2.5-3-fold) decrease in phagocytosis and complement activity, a drastic drop in T-, B-lymphocyte and T-helper content and a depression in T-lymphocyte functional activity have been observed. All this was accompanied by the activation of allergic and autoimmune reactions. Single transfusion of extracorporally X-ray-irradiated autoblood (5-7% of circulating blood volume) promoted an earlier normalization of the patients' critical condition and a prompt correction of the immune shifts.

Adolescent↗
PubMed1991

[Effectiveness of dioxidine in a model of Staphylococcal necrotic-suppurative encephalomeningitis (according to electron microscopy data].

Dioxidine efficacy was studied on a model of staphylococcal necrotic suppurative encephalomeningitis. There was a relationship of the development of disease signs to the value of the contaminating dose. Dioxidine was shown to have a therapeutic effect. Purulent inflammation in the brain either undevelop or was more limited. Examination of the changes in the ultrastructure of the nervous tissue also confirmed the efficacy of dioxidine. The treated mice had single inflammation infiltrations in the presence of the intact structure of the nervous tissue, the cell composition of the infiltrations changing in the direction of predominance of the mononuclear phagocytes. The phagocytes were in the state of hyperactivity and phagocytosis was of the completed nature. Secondary phagocytosis of the phagocytes and cell detritus was recorded.

Animals↗
PubMedDate not supplied

[Determination of the level of heparinization necessary to provide cascade filtration exchange plasmapheresis in patients with generalized suppurative peritonitis].

Activated clotting time was determined during cascade filtration exchange plasmapheresis (CFEP) in 24 patients with generalized suppurative peritonitis. A modified method of activated clotting time determination, using a home-made infusorial earth substitute of the type of "Kieselguhr" was used. A gradual decrease in activated clotting time during CFEP has been observed, which required additional heparin administration. By the end of the procedure, when the removed plasma volume reached 1500 ml, activated clotting time values returned practically to baseline.

Adult↗
PubMed1991

[Pars plana vitrectomy in the treatment of exogenous suppurative endophthalmitis].

The authors evaluate the results of pars plana vitrectomy (PPV) in 12 patients with exogenous suppurative endophthalmitis (EHE). EHE developed after operation of cataract in eight patients and after perforating injury of the sclera in four patients. The shape, size and appearance of the eye was preserved in 11 eyes, the function of the eye with a visual acuity of 0.5-1.0 was saved in six eyes (50%), in one eye with bacteriologically confirmed mycotic enophthalmitis and in five eyes where bacterial infection was assumed. Inoperable detachment of the retina characterized the ophthalmoscopic finding in all eyes with loss of function. Close cooperation of ophthalmological departments with vitreoretinal centres and early performance of urgent surgery are the basic prerequisites of better functional results of PPV in EHE.

Adult↗
PubMed1991

[The use of xymedon for wound healing stimulation and prevention of suppuration of surgical wounds].

Xymedon, a new preparation of the pyrimidine series, was studied in experiment and in the clinic. Experiments showed that on the 5th postoperative day the tensile strength of the scar was greater by 57% and the elasticity strength was greater by 21.5% in animals given Xymedon that in the control animals; the tensile strength was 42.4% greater than in animals given methyluracil. Oral administration of Xymedon in the postoperative period in 92 patients with various forms of acute appendicitis allowed earlier removal of the sutures and reduction of the number of wound complications from 13.8 to 3.3%, as a result of which the patients were discharged from the clinic within a shorter period. The authors recommend Xymedon as a stimulator of reparative processes in the wound and for the prevention of postoperative wound suppuration in emergency abdominal surgery.

Animals↗
PubMed1990

[Study of the mucociliary transport rate in evaluating the effectiveness of the treatment of suppurative endobronchitis by CO2 laser].

The rate of mucociliary transport (MCT) in dogs with an experimental pulmonary tuberculosis and concurrent suppurative endobronchitis (SEB) and just with the latter was measured. The treatment effect was achieved by an endobronchial radiation with a CO2-laser unfocused beam of 3.56 and 5.3 w/cm2 power density, and the dogs in the control group were subjected to an endobronchial introduction of furagin. A comparison of the endoscopic picture and MCT rate findings made it possible to believe that the latter index appeared to be more reliable than a visual inspection of the bronchial mucous membrane. An active specific process in the lungs brings about MCT rate inhibition while the concurrent SEB aggravates these changes to a great extent. The radiation of the bronchial mucous membrane with the CO2-laser unfocused beam produces an immediate positive effect on MCT rate normalization. Better results were observed at a power density of 3.56 w/cm2.

Animals↗
PubMedDate not supplied

[Local abdominal hypothermia in the intensive treatment of children with diffuse suppurative peritonitis].

Local abdominal hypothermia in intensive therapy of peritonitis in children checked abdominal inflammation, prevented the onset of hyperthermic reactions, promoted early stabilization of central hemodynamic parameters and early normalization of humoral immunity and led to certain clinical improvement. Taking into consideration the above data as well as possible indications and contraindications one can recommend local abdominal hypothermia for intensive therapy of generalized suppurative peritonitis in children.

Abdominal Muscles↗