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From gavage to oral feedings: just a matter of time.

The ability to safely and efficiently feed by mouth is based on oral-motor competence, neurobehavioral organization, and gastrointestinal maturity. Although most infants successfully make the transition to oral feedings as they approach term gestation, infants who were very immature at birth have historically had the most difficulty achieving this milestone. Postnatal complications (chronic lung disease, intraventricular hemorrhage, seizures, and so on) are also associated with delays in the onset of the first feeding, as well as with delays in achieving full enteral intake. Weaning the infant to breast is a slow and gradual process that may necessitate supplemental gavage or bottle feedings. A variety of measures--such as positioning, containment, reduced milk flow, and imposed rest breaks--may help to facilitate better oral intake, but infants probably benefit most from the passage of time. Frequently, the older the infant is at first feeding, the shorter the time required to make the transition to full oral feedings. Rather than attempting to accelerate the inherent maturational processes that form the basis for oral feeding, efforts might better be spent in providing adequate nutritional support while avoiding unnecessary stress and fatigue.

Age Factors↗

Efficiency of converting nutrient dry matter to milk in Holstein herds.

Production of milk from feed dry matter intakes (DMI), called dairy or feed efficiency, is not commonly measured in dairy herds as is feed conversion to weight gain in swine, beef, and poultry; however, it has relevance to conversion of purchased input to salable product and proportion of dietary nutrients excreted. The purpose of this study was to identify some readily measured factors that affect dairy efficiency. Data were collected from 13 dairy herds visited 34 times over a 14-mo period. Variables measured included cool or warm season (high ambient temperature <21 degrees C or >21 degrees C, respectively), days in milk, DMI, milk yield, milk fat percent, herd size, dietary concentrations (DM basis) and kilograms of crude protein (CP), acid detergent fiber (ADF), neutral detergent fiber (NDF), and forage. Season, days in milk, CP % and forage % of diet DM, and kilograms of dietary CP affected dairy efficiency. When evaluated using a model containing the significant variables, dairy efficiency was lower in the warm season (1.31) than in the cool season (1.40). In terms of simple correlations, dairy efficiency was negatively correlated with days in milk (r = -0.529), DMI (r = -0.316), forage % (r = -0.430), NDF % (r = -0.308), and kilograms of forage (r = -0.516), NDF (r = -0.434), and ADF (r = -0.313), in the diet, respectively. Dairy efficiency was positively correlated with milk yield (r = 0.707). The same relative patterns of significance and correlation were noted for dairy efficiency calculated with 3.5% fat-corrected milk yield. Diets fed by the herds fell within such a small range of variation (mean +/- standard deviation) for CP % (16.3 +/- 0.696), NDF % (33.2 +/- 2.68), and forage % (46.9 +/- 5.56) that these would not be expected to be useful to evaluate the effect of excessive underfeeding or overfeeding of these dietary components. The negative relationships of dairy efficiency with increasing dietary fiber and forage may reflect the effect of decreased diet digestibility. The results of this study suggest that managing herd breeding programs to reduce average days in milk and providing a cooler environment for the cows may help to maximize dairy efficiency. The mechanisms for the effects of the dietary variables on dairy efficiency need to be understood and evaluated over a broader range of diets and conditions before more firm conclusions regarding their impact can be drawn.

Animal Feed↗

Chronic toxicological evaluation of dietary NovaSil clay in Sprague-Dawley rats.

NovaSil (NS) clay, a common anti-caking agent in animal feeds, has been shown to sorb aflatoxins in the GI tract and diminish their bioavailability and adverse effects in short-term animal studies. Based on this evidence, it is hypothesized that clay-based enterosorption of aflatoxins may be a useful strategy for the prevention of aflatoxicosis in human populations. However, the potential toxicity of long-term dietary exposure to NS has not been determined. In this research, 5-6-week-old male and female Sprague-Dawley rats were fed rations containing 0, 0.25, 0.5, 1.0, or 2.0% (w/w) levels of NS for 28 weeks. Analysis of the NS showed negligible levels of dioxin and furan contaminants. Total feed consumption, cumulative feed consumption, body weight, total body weight gain, feed conversion efficiency, cumulative feed conversion efficiency, and relative organ weights were unaffected in either sex at the doses tested. No NS-dependent differences in relative organ weights or gross or histopathological changes were observed. Analysis of hematological parameters, clinical chemistry, and selected vitamin and mineral levels revealed isolated significant differences between some treatments and control groups (mean corpuscular hemoglobin, serum Ca, serum vitamin A, and serum Fe). However, the differences observed in each case were not dose-dependent. These results suggest that dietary inclusion of NS at levels as high as 2.0% (w/w) does not result in overt toxicity. These findings (as well as others) support the use of NS clay for dietary intervention studies in human populations at high risk for aflatoxicosis.

Absorption↗

Effects of fish meal in beef cattle diets on growth performance, carcass characteristics, and fatty acid composition of longissimus muscle.

We investigated the effects of fish meal (FM) in beef cattle diets on growth performance, carcass characteristics, and fatty acid (FA) composition of longissimus muscle in 63 yearling steers (335 +/- 23 kg). High-moisture corn and alfalfa silage diets were supplemented with either a corn gluten/blood meal mixture or FM at 10% of the diet. Fish meal contained (as-is basis) 5.87 g/kg eicosapentaenoic acid (EPA) and 9.84 g/kg docosahexaenoic acid (DHA). Seven strategies were developed to feed either a control diet (no FM) or diets containing 5 or 10% FM with FM fed for either 56, 112, or 168 d before slaughter. Average daily gain and feed efficiency were not affected (P > .10) by FM feeding but DMI decreased. Within FM diets, cattle fed 5% FM consumed more (P < .01) DM and gained more (P < .02) than cattle fed 10% FM. Carcass traits were not affected (P > .05) by feeding strategy except for fatter (P < .05) and lower (P < .06) yielding carcasses in cattle fed 5 vs 10% FM diets. Fish meal feeding increased (P < .01) concentrations of (n-3) FA, including EPA and DHA, and decreased (P < .05) concentrations of arachidonic acid. Increasing the amount of dietary FM further increased (P < .01) concentrations of EPA and DHA and decreased (P < .05) concentrations of (n-6) FA. We estimate that a 114-g steak from cattle fed 10% FM would supply 35 to 90% of the current average daily intake of EPA and DHA in North America. The results indicate that FM may have a role in niche marketing of beef provided that eating quality is not compromised.

Animals↗

Impact of alfalfa maturity and preservation method on milk production by cows in early lactation.

Ninety-six cows in early lactation were used in two experiments to measure the impact of alfalfa maturity (early or midbud vs. early or midbloom) and method of forage preservation (silage vs. hay) on DMI and milk production. Silage diets were fed as TMR, and hay was fed separately from grain. All diets contained 60% alfalfa (dry basis) and were balanced for 19% CP. Maturity had little effect on milk production in either experiment. Adjusted milk production for early cut silage, late cut silage, early cut hay, and late cut hay were 33.6, 33.4, 30.7, and 32.1 kg/d for Experiment 1 and 38.1, 37.0, 35.0 and 35.0 kg/d for Experiment 2. Increased alfalfa maturity tended to reduce DMI. Cows fed the silage diets consumed 1.2 kg more DM and produced an average of 2.1 kg more milk daily in Experiment 1 than those fed the hay diets. All treatment groups consumed similar amounts of DM in Experiment 2; however, cows fed silage produced 2.6 kg/d more milk than those fed hay. Preserving alfalfa as silage and feeding in a TMR to cows in early lactation resulted in greater milk production via increased DMI or improved feed efficiency compared with preserving alfalfa as hay and feeding grain separately.

Animal Feed↗

Supplemental protein sources for steers fed corn-based diets: II. Growth and estimated metabolizable amino acid supply.

Seventy Simmental-cross steers (average initial weight 301 +/- 24 kg) were individually fed in a 175-d completely randomized design experiment to evaluate the effects of source and level of protein in the diet on gain and feed efficiency. Steers were allotted to 1 of 10 treatments (seven steers per treatment) in a 3 x 3 factorial arrangement of treatments plus a urea-supplemented control diet. Main factors were source of supplemental protein (soybean meal [SBM], a high ruminal escape soybean meal [SP; SoyPLUS], or a combination of corn gluten meal and blood meal [CB; 50:50 on a nitrogen basis]) and level of each protein source (20, 30, or 40% of total dietary CP). Based on 18-h in situ ruminal incubation, escape N content of the protein sources was 66.0, 82.5, and 90.8% of total N and metabolizable amino acid (MAA) content was 29.1, 33.4, and 67.8 g/100 g of DM for SBM, SP, and CB respectively. The steers were fed 12.5% CP diets based on cracked corn (70%) on d 0 through 70 and were switched to a common 11.5% CP urea-supplemented cracked corn diet (80%) on d 71. The steers were housed in individual confinement stalls and had ad libitum access to feed. Replacing urea with SBM or SP increased (P < .05) 28- and 70-d ADG and DMI and increased (P < .05) 28-d efficiency (kg of gain/100 kg of feed). Replacing urea with CB did not improve (P > .05) 28- or 70-d ADG or DMI but did increase (P < .05) 28-d efficiency. The growth rate of steers at 28 and 70 d was correlated to a greater degree with ME intake (r2 = .83 and .85, respectively) rather than MAA supply, suggesting that the MAA supply was not first-limiting for growth. The source of supplemental protein fed during d 0 through 70 had no effect (P > .05) on 175-d DMI or efficiency; however, feeding SBM increased (P < .05) 175-d ADG compared with feeding urea, SP, or CB. Increasing supplemental true protein tended to linearly increase ADG and DMI at 28 and 70 d, but overall, ADG, DMI, and efficiency were not affected (P > .05) by treatment. Replacing urea with SBM or CB in the first 70 d decreased (P < .05) carcass quality grade, dressing percentage, and longissimus muscle area.(ABSTRACT TRUNCATED AT 400 WORDS)

Amino Acids↗

Investigation and management of dysphagia.

Dysphagia is a common finding in infants and children with neuromuscular disabilities. Dysphagia may be developmental, as in the preterm infant, transient, chronic, or progressive. The evaluation of dysphagia must take into account the age of the patient and typical development of feeding and swallowing for that age. The typical abilities seen in neonatal, early infancy, later infancy and early childhood periods vary in sensorimotor skills and feeding efficiency. In addition to knowing the substrate of expected skills by age, knowledge of the neurophysiology of feeding and swallowing is essential to diagnosis. Each physiologic phase of deglutition: oral, pharyngeal, and esophageal can present with symptoms of dysphagia that can guide investigation. Common symptoms of dysphagia include generalized feeding difficulty such as poor efficiency, food refusal and failure to thrive. Specific symptoms include tongue thrust, choking, cough, and oxygen desaturation. The possibility of dysphagia can be identified through a thorough feeding history. Examination initially includes the infant's muscle tone and posture in the head, neck and body. Anomalies of structures of the head and neck must be identified and examined for their effect on function. Next, examination of oral structures for reflexes, tongue movements, and symmetry will identify neurologic abnormalities. Observation of feeding is essential and will reveal signs of dysphagia. Aspiration in the infant can present without specific signs. Respiratory abnormalities or Gastroesophageal reflux can be identified during history or examination. Investigation of dysphagia most commonly includes videofluoroscopy, endoscopy, and ultrasonography. The management of dysphagia requires an individualized approach and will include neurologic, respiratory, nutritional and possibly gastrointestinal management. Six broad areas are identified that must be considered in the management of dysphagia in infants and children. They include: normalization of posture and positioning, adaptation of foods and feeding equipment, oromotor therapy, feeding therapy, nutritional support and management of associated disorders. A team of professionals will assist the parent and child in achieving pleasant feedings to foster appropriate growth and development.

Deglutition↗

Histological alterations of intestinal villi in chickens fed dried Bacillus subtilis var. natto.

Two experiments were conducted. In experiment 1, chickens were fed dried Bacillus subtilis var. natto for 3 or 28 days. Growth performance and internal organs were not different from controls, but feed efficiency tended to be improved in the 28-day feeding. In these birds, blood ammonia concentration was decreased (P<0.05). Blood glucose concentration, and amylase and lipase activity in the intestinal content were not significantly different among dietary groups. These results suggest that the B. subtilis natto depressed ammonia concentration. In experiment 2, chickens were fed dietary B. subtilis natto for 28 days. These birds had a tendency to display greater growth performance and intestinal histologies, such as villus height, cell area and cell mitosis, than the controls. Flat cell outline on the duodenal villus surface in controls developed large, protruded cell clusters and cell protuberances after feeding of dietary B. subtilis natto. These results indicate that intestinal function was activated by the depressed blood ammonia concentration in the body of the chicken. The present results may suggest that the B. subtilis natto has the potential to be a beneficial microorganism in chickens.

Amylases↗

Effect of porcine-derived mucosal competitive exclusion culture on antimicrobial resistance in Escherichia coli from growing piglets.

While use of antimicrobial drugs in livestock production has made a significant impact on animal health, welfare, and productivity, interest in suitable alternatives such as pre/probiotics, organic acids, and cultures of normal flora or "competitive exclusion" cultures from young animals has increased significantly in the wake of the antimicrobial resistance issue. The present study was undertaken to determine the effect of porcine-derived mucosal competitive exclusion (PCE) culture on both the antimicrobial susceptibility of commensal E. coli and on growth performance in piglets. Two replicate trials were conducted using growing piglets fed standard antimicrobial-free production diets. Piglets in the treatment group were orally dosed with PCE (10(10) cfu/mL) twice within 24 h of birth, at weaning, and 18-24 h post-weaning; control group piglets were dosed with sterile broth as a placebo. Fecal samples from all piglets were cultured for commensal E. coli at dosing times and when feed type was changed. A significantly higher proportion of E. coli from PCE-treated piglets demonstrated resistance to tetracycline (p < 0.0001), and streptomycin (p < 0.0001) when compared to controls. Resistance to streptomycin resistance in E. coli from piglets treated with PCE culture was variable, returning to baseline levels by day 21 (weaning). Piglets treated with the PCE culture demonstrated improved feed efficiencies when compared to control piglets (p < 0.005) during feeding of the starter and first growth diets. The PCE culture used in the present study had previously been shown to effectively exclude Salmonella in pigs. To the best of the authors' knowledge, this is the first report characterizing the effect of a competitive exclusion culture on antimicrobial resistance of commensal E. coli.

Animals↗

The effect of dietary protein level on threonine dehydrogenase activity in chickens.

An experiment was carried out to determine the effect of dietary protein level on the specific activity of hepatic L-threonine dehydrogenase in young growing chicks. Six replicate pens of seven Leghorn chicks were fed semipurified diets containing 23, 27, or 32% CP with identical relative proportions of amino acids in each protein group. Body weights and feed consumption were measured for 3 d, and hepatic mitochondria were isolated for assay of threonine dehydrogenase (TDH) activity. Weight gains and feed efficiency increased at each level of protein supplementation, but feed consumption was not affected by protein level. The specific activity of threonine dehydrogenase in isolated liver mitochondria was significantly (P < 0.05) higher in the 32% CP group than in the 23% CP group, and the activity in the 27% CP group was intermediate. We conclude that moderate increases in dietary protein level result in elevated hepatic threonine dehydrogenase activity in growing chicks.

Alcohol Oxidoreductases↗

Effects of red chilli (Capsicum frutescens L) on rats.

The effects of red chilli were examined in 12-w-old male Wistar rats fed a commercial diet mixed with ground Capsicum frutescens L fruits at levels of 2% and 10% (w/w) for 8 w. When compared with controls, the general health, body weight gain, feed intake and feed efficiency were not adversely affected on the rats on feed with 2% Capsicum, while the feed intake and growth rate were depressed and exfoliation of the intestinal epithelium into the lumen and cytoplasmic fatty vacuolation and necrosis of the centrilobular hepatocytes occurred in rats at 4 and 8 w on feed with 10% Capsicum. This correlated with changes in hematology, serum enzyme profiles and other serum constituents.

Animals↗

Fasting-refeeding regimes induce compensatory growth and muscle transcriptomic remodeling in juvenile Qihe gibel carp (Carassius gibelio var. Qihe).

Compensatory growth, an important adaptive response in fish, holds considerable potential for improving feeding efficiency in aquaculture. To identify an optimal fasting-refeeding strategy for juvenile Qihe gibel carp (Carassius gibelio var. Qihe) and to clarify the mechanisms underlying the compensatory growth, we divided two-month-old fish into four groups, namely S0 group (continuous feeding for 28&#xa0;days), S2 group (4&#xa0;cycles of 2-day fasting followed by 5-day refeeding), S4 group (fasting for 4&#xa0;days followed by refeeding for 24&#xa0;days), and S8 group (fasting for 8&#xa0;days followed by refeeding for 20&#xa0;days), then growth performance, muscle tissue morphology, biochemical responses, and muscle transcriptomic profiles under different feeding regimes were investigated. After a 28-day aquaculture experiment, fish in the S4 group exhibited significantly greater body length and weight than those in the S0, S2, and S8 groups, indicating over-compensatory growth. Histological analysis further showed that muscle growth in the S4 group was mainly associated with myofiber hyperplasia. Different feeding regimes also induced distinct changes in hepatic antioxidant and metabolic enzyme activities, as well as intestinal digestive enzyme activities. Transcriptome analysis revealed that the forkhead box O (FoxO) signaling pathway was significantly enriched during compensatory growth. Key genes, including serum/glucocorticoid regulated kinase 1 (sgk1) and insulin receptor substrate 1 (irs1), were predicted to play important roles in this process. Overall, these results indicate that fasting for 4&#xa0;days followed by refeeding for 24&#xa0;days (the S4 regime) is the optimal strategy for inducing compensatory growth in juvenile Qihe gibel carp. This study provides new insights into the morphological, physiological, and molecular basis of compensatory growth and offers a scientific foundation for developing efficient and sustainable feeding strategies for this species.

Animals↗

The effects of ractopamine hydrochloride on lean carcass yields and pork quality characteristics.

One hundred eighty barrows were evaluated to determine the effects of ractopamine hydrochloride (RAC) on lean carcass yields and pork quality. The pens were blocked by weight (six pens per block) with starting block weights of 69.0, 70.7, 73.8, 76.6, 78.4, and 84.3 kg. Pens within a block were assigned randomly to one of three RAC treatments so each treatment in a block was replicated twice. Treatments (as-fed basis) included control diet, 10 ppm of RAC added (R10), and 20 ppm of RAC added (R20) and ranged from 25 to 41 d depending on block. Pigs were slaughtered by blocks when block average live weights were 109 kg. Gain and feed efficiency were improved (P < 0.05) with increasing dietary concentrations of RAC, but feed intake did not differ (P > 0.05). Dressing percentage was higher (P < 0.05) for RAC-treated pigs. Subjective color, firmness, marbling scores, and Minolta L* reflection of the LM were not different (P > 0.05) among treatments. Carcass weights were heavier (P < 0.05) for pigs treated with RAC compared with control pigs and were higher for R20 than for R10. The RAC-fed pigs had greater (P < 0.05) yields (actual and percentage of HCW) of the following Institutional Meat Purchase Specification (IMPS) cuts than control pigs: trimmed, boneless ham (IMPS-402C and IMPS-402G), loin (IMPS-414), sirloin, and Boston butt (IMPS-406A). Pigs treated with RAC had a greater (P < 0.05) percentage of fat-free lean trimmings (IMPS-418) than did control pigs. Pigs treated with the R20 concentration had increased (P < 0.05) water-holding capacity compared with control pigs. Purge loss decreased linearly (P < 0.05) with increasing RAC compared with control for 14-d aged, non-enhanced loins. Warner-Bratzler shear (WBS) force values measured for nonenhanced chops were greater for RAC-treated pigs than for control pigs with a low dose response (P = 0.001). Enhanced chop (salt and phosphate injection) WBS values did not differ (P > 0.05) among dietary treatments. Trained sensory evaluation panel results for tenderness decreased in a low-dose plateau response fashion for nonenhanced chops (P = 0.004). Tenderness of enhanced chops decreased linearly (P = 0.04) with increasing RAC concentrations. No differences (P > 0.05) were found in juiciness or flavor of enhanced or nonenhanced chops. Feeding RAC to late-finishing swine resulted in faster growing, more efficient animals with increased boneless subprimal yields, and it had little effect on pork juiciness and flavor.

Adrenergic beta-Agonists↗

Pancreatic islet transplantation improves body composition, decreases energy intake and normalizes energy efficiency in previously diabetic female rats.

We investigated the weight gain, body composition, and feed efficiency of female Wistar Furth rats (170 +/- 1 g) made diabetic with streptozotocin (55 mg/kg intravenously), then infused intraportally with 3519 +/- 838 (150 mu equivalent units) syngeneic pancreatic islets of Langerhans. After islet transplants (5-6 wk), nutritional energetics were evaluated in transplanted rats (Transplant), and also in 3- and 9-wk diabetic (Diab-3, 9) and control rats treated with sham infusions and similar surgical manipulations (Sham-3, 9). Diabetic rats demonstrated marked hyperphagia, which was corrected by islet transplantation (577 +/- 53 vs. 266 +/- 19 kJ/d; P < 0.0001) and was not different than sham control rats (285 +/- 24 kJ/d; P > 0.05). Three weeks of diabetes resulted in a lower protein (Diab-3, 24.8 +/- 2.6 g vs. Sham-3, 30.9 +/- 1.0 g) and fat content (1.9 +/- 0.8 g vs. 11.6 +/- 1.7 g) in the rats' carcasses. However, 6 wk after islet transplantation, rats receiving islets (Transplant) were not different than control rats (Sham-9) (31.9 +/- 1.7 g vs. 33.3 +/- 1.9 g protein and 15.4 +/- 3.0 g vs. 15.1 +/- 3.2 g fat). Three weeks of diabetes resulted in a lesser energy efficiency compared with Sham rats (2.7 +/- 2.0 vs. 7.1 +/- 1.9 kJ gained/100 kJ ingested); islet-transplanted rats were not different than Sham-9 rats (4.9 +/- 2.3 vs. 4.7 +/- 1.4 kJ gained/100 kJ ingested). These data illustrate that islet transplantation in previously diabetic female rats improves growth with proportional gains in body protein and fat mass. This is modulated in part by a reduced food intake and an energy efficiency that is improved relative to controls. These studies offer an optimistic outlook for the continued development of more physiological insulin delivery strategies that preclude the nutritional complications associated with exogenous insulin administration.

Animals↗

Growth performance and intestinal microbial populations of growing pigs fed diets containing sucrose thermal oligosaccharide caramel.

Four experiments were conducted to determine growth performance and changes in intestinal microbial populations of growing pigs fed diets containing sucrose thermal oligosaccharide caramel (STOC). Ninety-six barrows and 96 gilts were group-fed experimental nursery diets for 32 d after weaning in both Exp. 1 and 2. For each experiment, pigs were divided into four groups of 48 pigs and were fed either control, antibiotic (Apramycin sulfate, 34 mg/kg), 1% STOC, or 2% STOC diets for 32 d after weaning. Each diet was replicated six times with eight pigs per replication. Pigs were either orally gavaged (Exp 1) with water of STOC (2 g per pig) or pigs were creep-fed (Exp 2) either a control diet or a 2% STOC diet for 5 d before weaning (33 d). At the end of Exp 1 and 2, cecal material was collected for enumeration of total aerobes, total anaerobes, coliforms, lactobacilli, and bifidobacteria. Gilts (96 per experiment) used in Exp. 3 and 4 were weaned at 26 d and fed experimental nursery diets for 32 d. They were fed either a control or 1% STOC diet and were otherwise treated as previously described. There were no significant effects of STOC or antibiotic on ADG, ADFI, feed efficiency, or cecal microbial populations in pigs in this study. Feeding diets containing either antibiotic of STOC did not improve animal performance or change intestinal bacterial populations in the present study.

Animals↗

Cyclic watering of broiler cockerels.

Two trials were designed to compare the performance of broilers receiving free access to water with those receiving cyclic access to water. Birds that received water in cyclic pattern were presented water by the activation of waterers for 15 min in each 3-h cycle (Trial 1) or 30 min in each 4-h cycle (Trial 2). In each trial, the control group received water ad libitum. Feed and water consumption and body weight were reduced in the cyclic-watered birds after 21 days of age in Trial 1 and were not different in the cyclic-watered birds in Trial 2 when compared with values for controls. Water:feed ratio and feed conversion values of the cyclic-watered birds were not altered by the cyclic watering regimens used in Trials 1 and 2. Observations of drinking patterns in Trial 2 demonstrate that the cyclic presentation of water can induce meal-drinking in cyclic-watered birds, but the feeding pattern of these birds was not altered. These data demonstrate that alteration of drinking activity can be accomplished without affecting growth and feed efficiency, and that altered drinking activity does not necessarily alter feeding activity.

Animals↗

Nutrition of the broiler chicken around the period of compensatory growth.

Three experiments were conducted with cage-reared broilers to 21 d following nutrient restriction from 6 to 12 d age. In Experiment 1, birds were full-fed from 6 to 11 or given 50% of ad libitum intake on a daily basis, or 100% of ad libitum intake on a daily basis when the diet was diluted 50% with oat hulls. Birds were not able to fully recover body weight depression by 21 d, although birds previously restricted, by whatever method, were more efficient (P < 0.01) in overall energy intake:body weight gain. Prior feed restriction had no effect on ability to metabolize diet energy (P > 0.05), although these birds did exhibit increased nitrogen retention compared to birds full-fed from 6 to 11 d. In a second experiment, birds were fed diets with 1.25, 1.38, 1.51, 1.63, 1.76, or 1.88% lysine in the realimentation diet from 12 to 21 d. Lysine level had no effect on growth rate or feed efficiency (P > 0.05) for full-fed birds; however there was a linear (P < 0.05) decline in growth rate from 12 to 21 d in response to extra dietary lysine for the birds previously feed restricted from 6 to 12 d. In a third experiment, birds were fed diets varying in energy (3,000 to 3,300 kcal/kg) or protein (22 to 29% CP) from 12 to 21 d following ad libitum vs 50% feed restriction from 6 to 11 d age. Protein level of the diet had little effect on performance traits to 21 d, although there was an indication of improved growth in response to the higher energy concentration. Birds full-fed from 6 to 11 d showed increased liver size at 21 d when fed more protein, although the converse was true for the restricted birds (P < 0.05). The growth response to diet energy was associated with increased carcass fatness. In general, there does not seem to be any advantage to manipulating diet formulation during realimentation of birds previously nutrient-restricted.

Abdomen↗

Effect of substitution of sugarbeet pulp for barley in diets for finishing rabbits on growth performance and on energy and nitrogen efficiency.

One hundred forty New Zealand White x California weanling rabbits were used to study the influence of increasing dietary contents of digestible fiber replacing nonstructural carbohydrates on feed efficiency and growth performance. Four diets, formulated by replacing sugarbeet pulp (SBP) for barley grain, and two slaughter weights (2 or 2.5 kg) were used in a 4 x 2 factorial arrangement. Inclusion of 15% SBP decreased dietary energy and CP digestibilities by 6% (P < .001), but nonsignificant effects were found on growth performance, empty body composition, and DE and digestible CP efficiencies for growth. Higher levels of SBP (35 and 50%) led to leaner animals and did not affect DE intake but greatly impaired (P < .001) DE and nitrogen efficiencies, NEg intake, growth rate, and dressing percentage in relation to the control diet. Inclusion of SBP increased the weight of gut contents (P < .001) and decreased cecal pH (P < .001), with no significant effect on mortality. Slaughter weight did not affect growth rate or energy efficiency but impaired (by 13%, P < .001) feed conversion rate. Higher (P < .001) energy content in live weight gain (12.5%) and dressing percentage (3.2%) were observed for rabbits slaughtered at 2.5 kg than for those slaughtered at 2 kg. Our data indicate that SBP can replace 15% of barley grain without decreasing growth performance, although energy and nitrogen efficiencies were impaired by 5%.

Animal Feed↗