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[Status of the sympathetic-adrenal system in children with suppurative peritonitis].

An increased excretion of catecholamines with the day urine was found in 166 children with diffuse and local peritonitis in acute period. A continuous suppurative process in the abdominal cavity and reoperations inevitably resulted in marked exhaustion of the sympatho-adrenal system and disturbed balance of its sympathetic and adrenal links. It is necessary to make up the catecholamine pool by the introduction of precursors, e.g. L-DOPA which will promote compensatory, regulatory and trophic influences upon processes of regulation and metabolism in the organism.

Adolescent↗

[Immunologic criteria of severity of suppurative infections in patients on programmed hemodialysis].

Certain parameters of the immune system were studied in patients under programmed hemodialysis with and without pyo-inflammatory complications. It was found that patients without pyo-inflammatory diseases are characterized by the state of immune deficiency while in patients with purulent infection the degree of inhibition of immune response of the organism correlates with spread of the suppurative process.

Humans↗

[Experience with and the prospects of using a single polypropylene thread in surgery of suppurative wounds].

A polypropylene monofilament in placing secondary sutures causes minimal damages in the tissues. The absence in a monofilament of the capillary-filtrative properties prevents the development of infiltrate, suppuration, dehiscence of the wound edges. In using a modified suture of the granulating wound, suggested by the authors, a good cosmetic and functional effect was noted.

Adolescent↗

[Comparative characteristics of the exudate elements of suppurative wounds in their treatment and stimulation of the reparative process with a powder-like composition with collagen base].

In use of a powdery composition containing the dry pharmaceutical collagen (20 component parts), ampicillin (20), methyluracil (1), dioxidine (1) for the treatment of suppurative wounds after different operative interventions on the abdominal organs, the wound cleaning of purulent-necrotic masses occurred in average 9 days, the onset of granulation formation--7.7, epithelization--8.4 days earlier than in patients treated by the conventional preparations. The mean duration of hospital stay reduced by 12.1 days.

Adolescent↗

[Acute diffuse peritonitis, a rare complication of perianorectal suppuration].

The paper reports on two peculiar clinical observations of diffuse acute peritonitis in which the abdominal cavity was contaminated by perianorectal suppurative acute processes, insufficiently solved surgically. The diagnosis difficulties, peculiarities of the surgical treatment, and their special seriousness are revealed.

Abscess↗

[Rehabilitation of patients with suppurative osseous complications of gunshot wounds of the shoulder in Ethiopia].

The authors have analysed the results of the treatment of 68 patients with pyo-osseous complications of the gunshot wounds of the shoulder which had been repeatedly operated at previous stages. The failures were connected with suppurations of the wounds, faults of the surgical technique and the postoperative management of the patient. All the patients were operated repeatedly at two stages: radical necrosequestrotomy, epidermatoplasty and tendoplasty were performed at stage I and bone autografting with immobilization with an plaster bandage were performed at stage II. The results of the treatment were good in 31 patients, satisfactory in 18 patients and not satisfactory in 6 patients. After tendoplasty the results were good in 12 patients and satisfactory in in 6 patients.

Bone Transplantation↗

[The suppuration of surgical wounds].

An analysis of wound complications in 699 patients after operation has been made. Microbiological examinations of the wound exudate have shown that the content of "seromas" and "hematomas" is infected with aerobic and anaerobic nonsporulating microflora in 80% of the cases. "Seromas" and "hematomas" were proved to be typical cases of suppuration of operative wounds.

Abdomen↗

[Prognostic criteria of suppurative-destructive complications in patients with a severe course of acute pneumonia].

54 patients with acute pneumonia were examined. There were 36 men and 18 women aged 16 to 72 years. Use was made of the clinico-roentgenological, bronchological and laboratory methods including biochemistry and immunoassays to assess the gravity of the patients' condition. The system protease inhibitors, the concentration of immunoglobulins in blood serum, circulating immune complexes, functional activity of neutrophils and monocytes of peripheral blood were under study. The major part of the patients (45 persons) did not develop destructive lesions, in 9 patients, pneumonia was complicated by suppurative-destructive lesions. In both patients' groups, the disease (in 90.3% of cases) ran its course with the signs of active virus infection. The risk factor for the destruction development was the rise of the laboratory gravity index to over 5-6 marks, a tendency towards the decrease of the phagocytic activity of monocytes and immunoglobulin M, the presence of unbalance in the system protease inhibitors at the expense of inadequate reduction of the antiproteolytic potential.

Acute Disease↗

[Suppurative pseudo-lithiasic canaliculitis].

The affection is often undiagnosed at the first stage. The second stage is characterized by a chronic suppurative canaliculitis with intra-canalicular concretions involving in many cases the lower canaliculus. Our 6 cases have been treated by a posterior canaliculotomy, a microsurgical evacuation of the concretions and a lacrimal tubing. It is not a fungal infection but a bacterial disease due to Actinomyces. Surgical treatment is very effective.

Actinomycosis↗

[Study of proteolytic enzymes and their inhibitors in maxillary sinus exudates in patients with chronic suppurative maxillary sinusitis].

Specific proteolytic and antitryptic activities were measured in the sinus exudate of 27 patients with chronic suppurative maxillary sinusitis. Most patients showed a shift in the proteinase-inhibitor system with proteolytic activity being predominant. In the course of treatment antitryptic activity in the exudate increased. It was found that biochemical data were correlated with clinical manifestations. It is concluded that patients with the above pathology should be prescribed proteolytic enzymes on an individual basis and that natural proteinase inhibitors should be included into the combined therapy.

Adolescent↗

[The role of ultrasonic diagnosis in selecting the surgical tactics in suppurative-inflammatory diseases of soft tissues].

Ultrasonography was conducted in 66 patients with postinjection infiltrations, abscesses, postoperative scar suppurations, mastitis and other inflammatory conditions. Ultrasonography detected abscesses at different sites in 32 patients. Accurate topical diagnosis and the assessment of the size of the cavity, the number of chambers and the state of the adjacent tissues determined the choice of surgical strategy for each individual case, a radical abscessectomy being preferred in most cases. Ultrasonographic diagnosis of soft-tissue phlegmons at different sites of the body also made possible an urgent choice of a radical surgical procedure.

Abscess↗

[Chronic suppurative bronchopathy and motility defect of neutrophils: evaluation of an immunomodulating treatment].

Five patients with recurrent infections of the lower respiratory tract, chronic bronchial suppuration and significant defect of polymorphonuclear granulocyte (PMN) motility were studied. Clinical evaluation and in vitro studies of PMN motility were performed before, during and after the treatment with levamisole chlorhydrate (2.5 mg/Kg twice a week). Clinical improvement was obtained in all the patients, together with a significant increase in the chemotactic response of PMN. No side effects were reported. After a follow-up of 7-18 months PMN chemotaxis remained normal in all the patients and a reappearance of respiratory symptoms was observed only in one subject.

Adolescent↗

[Differential correction of disorders of colloid-oncotic blood pressure in pregnant women and puerperants with suppurative-septic diseases].

The measurement of colloid-oncotic pressure (COP) in 160 women with pyoseptic disease (pyodermia, soft-tissue abscesses, suppurative mastitis, endometritis, sepsis) has demonstrated a regular pattern of change, depending on the clinical condition. A classification of COP disorders has been proposed, identifying the hyperoncotic state (COP above 3.29 kPa), normoncotic state (COP between 2.84 and 3.29 kPa) and hypo-oncotic state (COP below 2.84 kPa), on which a differential remedial therapy is based. A reliable assessment of COP values during the infusion therapy can only be made by means of oncometry, since estimations of any kind lead to considerable error.

Abscess↗