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At least 811 records · Page 45Linked to original sources

Retrobulbar anesthesia in strabismus surgery.

Forty-nine patients, ranging in age from 12 to 77 years, underwent strabismus surgery under local anesthesia. With standard preoperative medication and a retrobulbar injection of 2% mepivacaine hydrochloride (hyaluronidase added in 12 patients), effective anesthesia was obtained. Twenty-four patients were observed during the immediate postoperative period, and return of extraocular muscle function and visual acuity was found to be complete an average of 3.8 hours after the injection. The addition of hyaluronidase significantly altered the duration of the anesthetic. Local anesthesia may be a preferable technique in terms of decreased morbidity, especially in the older patient. The short duration of anesthesia and lack of side effects also enable the surgeon to use adjustable sutures and make the final adjustment relatively early in the postoperative period.

Adjuvants, Anesthesia↗

Retrobulbar anesthesia in strabismus surgery. II. Use of a short-acting anesthetic agent.

Forty-two patients underwent strabismus surgery with a retrobulbar injection of 3% chloroprocaine hydrochloride. In the 18 patients who were followed up in the immediate postoperative period, the average duration of action of 3% chloroprocaine was found to be 2.13 hours. In addition to the advantages of local anesthesia, this short-acting anesthetic permits earlier modifications of adjustable sutures and the earlier discharge of patients on the same day as surgery.

Adolescent↗

Variability of strabismus surgery for acquired esotropia.

We developed a mathematical model to predict the probable success rate of the first surgery to correct acquired esotropia with normal accommodative convergence-accommodation ratio in children. A computer-averaged dose-response curve of the effect of 68 bilateral medial rectus recessions was combined with various assumptions regarding likely errors in surgical performance and likely errors in measurement of the preoperative deviation. Fifteen different sets of reasonable assumptions were tested, giving a range of theoretical success rates from 72% to 96%. The results of this study clearly indicate that a certain proportion of failures is to be expected when this or other forms of strabismus are treated surgically by a fully competent ophthalmic surgeon performing as accurately as is practically possible.

Child↗

Botulinum treatment of strabismus following retinal detachment surgery.

Twenty patients with strabismus and diplopia following surgery for retinal detachment were treated by botulinum toxin injection of the eye muscles. Twelve patients had regained fusion with elimination of diplopia in the primary position at the time of examination, 5 to 96 months after treatment (mean, 24 months). Three patients had partial diplopia elimination, and five patients continued to have diplopia.

Adult↗

Vascular microdissection in strabismus surgery.

Microdissection of the muscular vessels allows recessions, resections, or transpositions of the recti muscles without interrupting the blood flow to the corresponding anterior ciliary arteries. This avoids postoperative impaired blood flow to the anterior segment and may play a role in preventing anterior segment ischemia syndrome. The use of a fine-hooked cannula and microscissors, in addition to the usual strabismus surgery instruments, is described.

Dissection↗

Conjunctival retraction suture for fornix adjustable strabismus surgery.

The fornix approach to strabismus surgery is advantageous because the incision is made under the eyelid, there is no need for conjunctival sutures, it is comfortable for the patient, and there is minimal postoperative scarring. The major disadvantage of the fornix approach for the adjustable suture technique has been poor exposure to the muscle-suture apparatus and poor postoperative knot exposure. We describe herein the use of a subconjunctival retraction suture for adjustable suture surgery with the fornix approach. This suture retracts the conjunctiva, exposing the adjustable muscle-suture apparatus while simultaneously fixating the globe. A novel way of tying the noose around the pole sutures and preventing noose slippage is also presented. This technique provides excellent exposure, fixation of the globe, and complete coverage of the knot with conjunctiva after adjustment.

Conjunctiva↗

Subconjunctival cysts as a complication of strabismus surgery.

Six patients were operated on for large subconjunctival cysts that developed up to 35 years after strabismus surgery. In four of these patients the cyst was found to arise between the anterior edge of the muscle and the site to which the muscle had been sutured during previous surgery. The muscle was attached to the posterior wall of the cyst and not to the sclera. A pseudotendon was found running between the point on the sclera to which the muscle had been sutured and the undersurface of the muscle far posteriorly. In the other two patients a sudoriferous cyst was found that the referring ophthalmologist had mistakenly thought to represent an abscess when excision was attempted.

Child, Preschool↗

Overgrowth, congenital hypotonia, nystagmus, strabismus, and mental retardation: variant of dominantly inherited Sotos sequence?

We report on 2 patients with macrocephaly, strabismus, esotropia, nystagmus, hypotonia, developmental delay, excessive size, unusual facial appearance, and improvement with age. Many of these abnormalities are present in Sotos sequence. The mothers of both patients share some characteristics with their children. These patients may represent an autosomal dominant form of Sotos sequence.

Female↗

Effects of experimental strabismus on the architecture of macaque monkey striate cortex.

Strabismus, a misalignment of the eyes, results in a loss of binocular visual function in humans. The effects are similar in monkeys, where a loss of binocular convergence onto single cortical neurons is always found. Changes in the anatomical organization of primary visual cortex (V1) may be associated with these physiological deficits, yet few have been reported. We examined the distributions of several anatomical markers in V1 of two experimentally strabismic Macaca nemestrina monkeys. Staining patterns in tangential sections were related to the ocular dominance (OD) column structure as deduced from cytochrome oxidase (CO) staining. CO staining appears roughly normal in the superficial layers, but in layer 4C, one eye's columns were pale. Thin, dark stripes falling near OD column borders are evident in Nissl-stained sections in all layers and in immunoreactivity for calbindin, especially in layers 3 and 4B. The monoclonal antibody SMI32, which labels a neurofilament protein found in pyramidal cells, is reduced in one eye's columns and absent at OD column borders. The pale SMI32 columns are those that are dark with CO in layer 4. Gallyas staining for myelin reveals thin stripes through layers 2-5; the dark stripes fall at OD column centers. All these changes appear to be related to the loss of binocularity in cortical neurons, which has its most profound effects near OD column borders.

Animals↗

Effects of strabismus and monocular deprivation on the eye preference of neurons in the visual claustrum of the cat.

Visual response properties of neurons in the dorsocaudal claustrum were studied in two cats reared with convergent strabismus and three cats reared with monocular lid-suture. In the normal claustrum, most cells respond about equally well to stimulation of either eye (Sherk and LeVay, '81). In the strabismic animals, there was a partial breakdown of binocularity: most cells remained binocular but were influenced more strongly by one eye (usually the contralateral eye) than the other. The loss of binocularity was less extreme in the claustrum than in area 17 of the same animals. In the monocularly deprived cats, claustral cells responded exclusively to the experienced eye. We interpret the changes observed in the claustrum as reflecting changes in the ocular dominance of cortical inputs to the claustrum, rather than as evidence for plasticity within the claustrum itself. Autoradiography was used to study the return projection from claustrum to cortex in monocular deprivation. The cortical labeling pattern resembled that seen in normal cats. To examine whether this return projection might be involved in reducing cortical responsiveness to the deprived eye, recordings were made from area 17 of a monocularly deprived cat before and after ablation of the ipsilateral claustrum by injection of kainic acid. Following ablation, there was no unmasking of cortical responses to the deprived eye. Thus the cortico-claustral loop does not appear to suppress cortical responses to the deprived eye.

Animals↗

Further evidence for the fusional nature of the compensation (or 'eating up') of prisms in concomitant strabismus.

The fusional nature of the phenomenon of prism compensation in strabismus was studied. At first a general survey was performed on the characteristics of anomalous fusional movements (a.f.m.). The influence of different kinds of stimuli (foveal and peripheral fusionable targets, non-fusionable targets) on a.f.m. was considered, and finally the effect of a sensorial obstacle to fusion was investiaged. It is concluded that 'eating up' the prisms is definitely a phenomenon of fusional nature, although it has special features which are interpreted as a consequence of the initial pathological condition. In this way the puzzling prism compensation also in subjects with normal retinal correspondence may be explained.

Child↗

Sensorio-motorial anomalies in strabismus: (anomalous movements).

The attempts at treating anomalous correspondence by prisms in esotropia have led to the observation that frequently the angle of deviation increases with prismatic correction. The convergent movements induced by base-out prisms in esotropic patients resemble normal fusional movements in some aspects; they are provisorily called 'anomalous movements' and the objective differences between anomalous movements and normal fusional movements are reported. The strength of 'anomalous movements' are investigated with prisms. This with the aim of better understanding this sensorio-motorial sequela of strabismus and possibly selecting those patients who are more apt for prismatic therapy. The main criteria adopted today for eliminating anomalous movements and the residual postoperative deviation related with them are listed. Finally, the way anomalous movements may interfere with surgery is discussed.

Color Perception Tests↗

Convergent strabismus fixus in high myopic patients.

Patients with high myopia may develop a myopathy which frequently results in a sort of convergent strabismus fixus. Echographic and CT scan findings give evidence that a myopathic paralysis of the lateral rectus is supported by a slow pressure on this muscle squeezed between the lateral orbital wall and the enlarged eyeball.

Adult↗

Non-fusable stimuli and the role of binocular inhibition in normal and pathologic vision, especially strabismus.

Stimuli on corresponding points of both retinae that cannot be fused may cause binocular rivalry: the stimuli suppress each other alternately. This effect was used to study the influence of image sharpness upon binocular inhibition. Blurring an image means decreasing its contrast and attenuating its high spatial frequencies. Both factors diminish the time that a stimulus is perceived during rivalry. This fact has implications both for normal vision--as objects off the horopter are normally blurred--and for disturbed vision when the image of one or both eyes is (locally) deteriorated. In both cases, the binocular field of view can be combined from the 'good' parts of both eyes. Hence, the field of view may consist, in a piece-meal fashion, of parts stemming from the right or the left eye exclusively and others where both images are superimposed. We present evidence for the hypothesis that there is a common neural mechanism causing both binocular rivalry and functional amblyopia in anisometropia and strabismus. Consequences of the results on rivalry suppression for the pathophysiology and therapy of strabismic amblyopia are discussed.

Adolescent↗

Surgical correction of convergent strabismus: its relationship to prism compensation.

Esotropic patients whose angle of strabismus has been corrected by prisms frequently increase their angle deviation to compensate for the prismatic correction. This sensorio-motorial reaction to prism correction has been given the name of anomalous movements (a.m.). Quantification of a.m. has been made according to the amount of prisms that an esotropic patient is capable of compensating for (progressive prism compensation test--p.p. test). Some esodeviation does not compensate for any prisms at all since a.m. have not yet developed. Other cases compensate for as much as 40 or 60 prism diopters and more of over-correction of the angle deviation and they therefore have powerful a.m. The interference of these innervational forces acting on the medial recti to corrective surgery has been studied in 126 operated esotropic patients. A significant decrease from the expected surgical result (p less than 0.001) has been found in patients having powerful a.m., as can be judged by the p.p. test. It is believed that a.m. are an important drawback contributing to vitiate any formula on the amount of muscle surgery to be performed in patients having no possibilities of restoring normal binocular vision. Practical advice on how to eliminate this drawback and theoretical reasoning on the significance of a.m. are offered.

Adaptation, Physiological↗

Natural strabismus in non-Siamese cats: lack of binocularity in the striate cortex.

Cats with a natural convergent squint were discovered within a colony of normal Mill Hill cats. In two of them single unit recording was undertaken in area 17. The ocular dominance distribution showed a clear disruption of binocularity in both hemispheres. This lack of binocular units was comparable to cats with artificial, surgically-induced strabismus and differed significantly from the ocular dominance distribution of a normal control group. The existence of these natural, non-albino squinters strengthens the use of cats as an animal model for strabismic amblyopia.

Animals↗